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The map label for this gene is glaA

Identifier: 29348569

GI number: 29348569

Start: 4028701

End: 4030407

Strand: Reverse

Name: glaA

Synonym: BT_3160

Alternate gene names: 29348569

Gene position: 4030407-4028701 (Counterclockwise)

Preceding gene: 29348573

Following gene: 29348563

Centisome position: 64.38

GC content: 37.02

Gene sequence:

>1707_bases
ATGATGAGCGTTTGGTTCATCCAGTTGGCTATTTTTGCCCAGTCTAGAATAATAGAGGTTTTTCCGGAGCAGGGAAAAGA
TATTGAAAATATAGCGTTAGCTTTAAAAAAAGCTGCTGACTGTAAAGGAAGGCCGGTTACTGTAAAGTTTTCACCGGGAA
TTTATCAGTTAGACCGTGCGAAATCATCACAAGTGTTATATTATATATCAAATACGACTTCTGAGTTGGATGATCCTGAT
CCGACTAAACATATCGGATTGTATCTTAATACATTAAAGAATATCACTATTGATGGTTGTGGGTCAACTTTATTGATGAA
TGGTGAAATGACAAGTTTCGTACTTGATAAATGTGAAGGTATTGTTTTGAAAAATTTTAATATAGATTATAAACATCCTA
CTCAAACAGAGGTTGAAGTATTGGAAGAGGGGAATGATTATTTGATTGTTCAGGTACATCCCACATCCCAATATCGGATT
GTAGACGCACAGTTGGAGTGGTATGGTGATGGTTGGTCTTTTAAGAACGGAATAGCGCAGTCGTATGACCGTATAAGTGA
AATGACTTGGCGTTCTTGGAGTCCGATGGAGAATTTGCTTCGTACAGTAGAACTTCGTCCAAATGTGTTATATCTGCAAT
ATAAAGAAAAACCACAAGTAGGACTACATACTATTTTTCAGATGCGCGATTCTTTCCGTGACGAAGTGAGTGGATTTGTA
AACAGAAGTAAGGGAATACTGTTGGAGAATATCAACTTCTATTATTTAGGAAATTTCGGGGTAGTCTGTCAATACAGTGA
GAATATTACTGTTGATCGTTGTAACTTTGCTCCTCGTCCAGGTTCAGGACGTACTAATGCGGGATTTGCTGATTTTATTC
AGGTTTCTGGTTGCCGTGGTATGATTGATATTAAGAATTCCCGTTTTATAGGTGCACACGATGATCCTATAAATATACAT
GGTACACATTTGCGAGTAATAGAATTTTTGTCGGACAATCGTTTAAAACTTCGTTTTATGCATGACCAGACTTTTGGATT
TGAAGCCTTTTTTAAAGGAGACGATATAGAACTTGTTGATTCACGTTCTCTGTTGGTAGTAGGGAAGTGTAAAGTAAAAG
AGGCAAAATTAGTAACGCCAAGAGAAATGGAACTCACTCTGTCAAGTCCACTCTCTTCGGAGGTAATGCAACAGAAAGAC
CTGGTTATTGAGAACGTGACGTGGACACCGGAAGTGCGGATTACAAACAATTACTTTGCAAGAGTACCAACCAGAGGGAT
TCTTATCACAACACGACGTAAGTCTCTGATAGAAGGAAATACATTCTACGGCATGCAGATGAGTGGAATATTTGTAGCCG
ATGATGGATTAAGCTGGTATGAGTCAGGACCGGTACATGACTTGACTATTCGTCAAAATACGTTTTTAAACTGTGGAGAA
CCGATTATTAGCATTGATCCGGAGAATAGAGAATATAAAGGGGCGGTTCATAAAAATATTACTATTGAAGAAAATTATTT
TTATATGAGAAAAAATAGCTCATGTGCCATTCGAGCGAAGGCTGTTGATGGTCTGATGATACGTCATAATTTGATTTATT
CTCTAGATACTGAAAAAAATAAAGAGTCTGATTTTATTCAGATGTATAATTGTAATGAAGTTACAATAAAAGAAAATCGG
GTACAGTTGCACCACCTATTTAAATAA

Upstream 100 bases:

>100_bases
TTTTGATTGCTTTATATCTATAATAGGGTATAGATAATTTCTATCTTTGTGAAAAAAGTAAAATTTGAAGATCAATATCA
TGAAAAAGTACATTTTATTT

Downstream 100 bases:

>100_bases
ATTCTATTTCAATTTTAAAAGAAATAGATAAATATATAGTAAAAGATTTGATTATAGTAAACCCTGGAAATTTATAATAC
AAACTTCCAGGGTTTATTTT

Product: hypothetical protein

Products: NA

Alternate protein names: BtGal110A; Exo-alpha-galactosidase A

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MMSVWFIQLAIFAQSRIIEVFPEQGKDIENIALALKKAADCKGRPVTVKFSPGIYQLDRAKSSQVLYYISNTTSELDDPD
PTKHIGLYLNTLKNITIDGCGSTLLMNGEMTSFVLDKCEGIVLKNFNIDYKHPTQTEVEVLEEGNDYLIVQVHPTSQYRI
VDAQLEWYGDGWSFKNGIAQSYDRISEMTWRSWSPMENLLRTVELRPNVLYLQYKEKPQVGLHTIFQMRDSFRDEVSGFV
NRSKGILLENINFYYLGNFGVVCQYSENITVDRCNFAPRPGSGRTNAGFADFIQVSGCRGMIDIKNSRFIGAHDDPINIH
GTHLRVIEFLSDNRLKLRFMHDQTFGFEAFFKGDDIELVDSRSLLVVGKCKVKEAKLVTPREMELTLSSPLSSEVMQQKD
LVIENVTWTPEVRITNNYFARVPTRGILITTRRKSLIEGNTFYGMQMSGIFVADDGLSWYESGPVHDLTIRQNTFLNCGE
PIISIDPENREYKGAVHKNITIEENYFYMRKNSSCAIRAKAVDGLMIRHNLIYSLDTEKNKESDFIQMYNCNEVTIKENR
VQLHHLFK

Sequences:

>Translated_568_residues
MMSVWFIQLAIFAQSRIIEVFPEQGKDIENIALALKKAADCKGRPVTVKFSPGIYQLDRAKSSQVLYYISNTTSELDDPD
PTKHIGLYLNTLKNITIDGCGSTLLMNGEMTSFVLDKCEGIVLKNFNIDYKHPTQTEVEVLEEGNDYLIVQVHPTSQYRI
VDAQLEWYGDGWSFKNGIAQSYDRISEMTWRSWSPMENLLRTVELRPNVLYLQYKEKPQVGLHTIFQMRDSFRDEVSGFV
NRSKGILLENINFYYLGNFGVVCQYSENITVDRCNFAPRPGSGRTNAGFADFIQVSGCRGMIDIKNSRFIGAHDDPINIH
GTHLRVIEFLSDNRLKLRFMHDQTFGFEAFFKGDDIELVDSRSLLVVGKCKVKEAKLVTPREMELTLSSPLSSEVMQQKD
LVIENVTWTPEVRITNNYFARVPTRGILITTRRKSLIEGNTFYGMQMSGIFVADDGLSWYESGPVHDLTIRQNTFLNCGE
PIISIDPENREYKGAVHKNITIEENYFYMRKNSSCAIRAKAVDGLMIRHNLIYSLDTEKNKESDFIQMYNCNEVTIKENR
VQLHHLFK
>Mature_568_residues
MMSVWFIQLAIFAQSRIIEVFPEQGKDIENIALALKKAADCKGRPVTVKFSPGIYQLDRAKSSQVLYYISNTTSELDDPD
PTKHIGLYLNTLKNITIDGCGSTLLMNGEMTSFVLDKCEGIVLKNFNIDYKHPTQTEVEVLEEGNDYLIVQVHPTSQYRI
VDAQLEWYGDGWSFKNGIAQSYDRISEMTWRSWSPMENLLRTVELRPNVLYLQYKEKPQVGLHTIFQMRDSFRDEVSGFV
NRSKGILLENINFYYLGNFGVVCQYSENITVDRCNFAPRPGSGRTNAGFADFIQVSGCRGMIDIKNSRFIGAHDDPINIH
GTHLRVIEFLSDNRLKLRFMHDQTFGFEAFFKGDDIELVDSRSLLVVGKCKVKEAKLVTPREMELTLSSPLSSEVMQQKD
LVIENVTWTPEVRITNNYFARVPTRGILITTRRKSLIEGNTFYGMQMSGIFVADDGLSWYESGPVHDLTIRQNTFLNCGE
PIISIDPENREYKGAVHKNITIEENYFYMRKNSSCAIRAKAVDGLMIRHNLIYSLDTEKNKESDFIQMYNCNEVTIKENR
VQLHHLFK

Specific function: Alpha-galactosidase that specifically removes branched alpha-1,3-linked galactose residues present in blood group B antigens. Has no activity toward linear alpha-1,3-linked galactose residues

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 PbH1 repeats

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLAA_BACTN (Q8A2Z5)

Other databases:

- EMBL:   AM109956
- EMBL:   AE015928
- RefSeq:   NP_812072.1
- GeneID:   1075907
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_3160
- NMPDR:   fig|226186.1.peg.3159
- OMA:   LKLRFMH
- ProtClustDB:   CLSK823424
- BioCyc:   BTHE226186:BT_3160-MONOMER
- InterPro:   IPR006626
- InterPro:   IPR012334
- InterPro:   IPR011050
- Gene3D:   G3DSA:2.160.20.10
- SMART:   SM00710

Pfam domain/function: SSF51126 Pectin_lyas_like

EC number: =3.2.1.22

Molecular weight: Translated: 65148; Mature: 65148

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSVWFIQLAIFAQSRIIEVFPEQGKDIENIALALKKAADCKGRPVTVKFSPGIYQLDRA
CCEEEEEEEEHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCC
KSSQVLYYISNTTSELDDPDPTKHIGLYLNTLKNITIDGCGSTLLMNGEMTSFVLDKCEG
CCCEEEEEEECCCCCCCCCCCCHHHHEEEECCCCEEEECCCCEEEECCCHHHHHHHCCCE
IVLKNFNIDYKHPTQTEVEVLEEGNDYLIVQVHPTSQYRIVDAQLEWYGDGWSFKNGIAQ
EEEEECCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCCCHHHH
SYDRISEMTWRSWSPMENLLRTVELRPNVLYLQYKEKPQVGLHTIFQMRDSFRDEVSGFV
HHHHHHHHCCCCCCHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NRSKGILLENINFYYLGNFGVVCQYSENITVDRCNFAPRPGSGRTNAGFADFIQVSGCRG
CCCCCEEEECCCEEEEECCCEEEEECCCCEEEECCCCCCCCCCCCCCCCHHEEEECCCCE
MIDIKNSRFIGAHDDPINIHGTHLRVIEFLSDNRLKLRFMHDQTFGFEAFFKGDDIELVD
EEEECCCEEECCCCCCCEEECCEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCEEEEC
SRSLLVVGKCKVKEAKLVTPREMELTLSSPLSSEVMQQKDLVIENVTWTPEVRITNNYFA
CCCEEEEEECCCCCCEECCCCEEEEEECCCCHHHHHHHCCCEEECCCCCCEEEECCCEEE
RVPTRGILITTRRKSLIEGNTFYGMQMSGIFVADDGLSWYESGPVHDLTIRQNTFLNCGE
ECCCCCEEEEECCCHHCCCCEEEEEEEEEEEEECCCCCHHCCCCEEEEEEECCCCCCCCC
PIISIDPENREYKGAVHKNITIEENYFYMRKNSSCAIRAKAVDGLMIRHNLIYSLDTEKN
CEEEECCCCCCCCCEEECCEEEECCEEEEEECCCEEEEEECCCCEEEEEEEEEEECCCCC
KESDFIQMYNCNEVTIKENRVQLHHLFK
CCCCEEEEEECCEEEEECCEEEEEECCC
>Mature Secondary Structure
MMSVWFIQLAIFAQSRIIEVFPEQGKDIENIALALKKAADCKGRPVTVKFSPGIYQLDRA
CCEEEEEEEEHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCC
KSSQVLYYISNTTSELDDPDPTKHIGLYLNTLKNITIDGCGSTLLMNGEMTSFVLDKCEG
CCCEEEEEEECCCCCCCCCCCCHHHHEEEECCCCEEEECCCCEEEECCCHHHHHHHCCCE
IVLKNFNIDYKHPTQTEVEVLEEGNDYLIVQVHPTSQYRIVDAQLEWYGDGWSFKNGIAQ
EEEEECCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCCCHHHH
SYDRISEMTWRSWSPMENLLRTVELRPNVLYLQYKEKPQVGLHTIFQMRDSFRDEVSGFV
HHHHHHHHCCCCCCHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NRSKGILLENINFYYLGNFGVVCQYSENITVDRCNFAPRPGSGRTNAGFADFIQVSGCRG
CCCCCEEEECCCEEEEECCCEEEEECCCCEEEECCCCCCCCCCCCCCCCHHEEEECCCCE
MIDIKNSRFIGAHDDPINIHGTHLRVIEFLSDNRLKLRFMHDQTFGFEAFFKGDDIELVD
EEEECCCEEECCCCCCCEEECCEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCEEEEC
SRSLLVVGKCKVKEAKLVTPREMELTLSSPLSSEVMQQKDLVIENVTWTPEVRITNNYFA
CCCEEEEEECCCCCCEECCCCEEEEEECCCCHHHHHHHCCCEEECCCCCCEEEECCCEEE
RVPTRGILITTRRKSLIEGNTFYGMQMSGIFVADDGLSWYESGPVHDLTIRQNTFLNCGE
ECCCCCEEEEECCCHHCCCCEEEEEEEEEEEEECCCCCHHCCCCEEEEEEECCCCCCCCC
PIISIDPENREYKGAVHKNITIEENYFYMRKNSSCAIRAKAVDGLMIRHNLIYSLDTEKN
CEEEECCCCCCCCCEEECCEEEECCEEEEEECCCEEEEEECCCCEEEEEEEEEEECCCCC
KESDFIQMYNCNEVTIKENRVQLHHLFK
CCCCEEEEEECCEEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928