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The map label for this gene is atsA [H]

Identifier: 29348515

GI number: 29348515

Start: 3950514

End: 3952166

Strand: Reverse

Name: atsA [H]

Synonym: BT_3106

Alternate gene names: 29348515

Gene position: 3952166-3950514 (Counterclockwise)

Preceding gene: 29348516

Following gene: 29348514

Centisome position: 63.13

GC content: 40.59

Gene sequence:

>1653_bases
ATGAAAAGAATAGATTATACTTTTATGTTGACCCTTGGTGCGTCAATAGGTGCTTGTCCTGTATTGGCCCAGCAGAATGT
ATCAAAACCTAATATTGTCCTTATATTATTGGATGATGTCGGATATTCCGATTTCGGATGTTATGGTTCGGAAATAAATA
CTCCTAATATAGATCGGCTTGCTGAAAATGGTATTAGACTACGTCATTTTTATAACCAGGCTCGGAGTGCGCCAACCAGG
GCTTCGTTGATTACTGGTTTATATCCTCATCAAGTTGGGAATGGTGCTTTAGGGAAAGTTCCGGGTTATCCGGCATATCA
GGGATATCCAAATGAGAATAATGTTTTCTTGCCTGAAGCATTGAAAACAGCTGGATATTTTAATGTCATGACAGGTAAAT
GGCATTTAGGATATTTTCAAGGTGTTACTCCAATAAGCAGAGGATTTGACCGTTCACTGAACGCTCCGTTTGGCGGCTAT
TATTTTTCTTCTGACAAATCATTGAAGAAGAATAAAAAAGAAAGAACCAACCAACGAAATCTTTATTTGAATGATGAAGA
AATTGGATTCGATGATGATCGTTTACCTGAAAATTGGTATTCTACTCATTTGTGGACAGATTTTGGATTAAAGTTTATTG
ATGAAGCTATTGAAGAAAAACAGCCCTTCTTTTGGTATCTGGCACATAATGCTGCACATTTTCCCTTGCAGGCTCCTGTA
GAAACCATCAATAAATATAAGGGAAAATATATGAAGGGATGGGAAGATGTGCGTAATGCACGATTCAAAAAGCAATTAGA
ATTAGGGTTATTCGAGCGTCCTGACCAGTTAACACCTCGTAATCCCAAGGTTCCGGAATGGGATTCACTGACTCAGGAAG
AAAAGGAGCGCTATGACATGCAGATGGCTATTTATGCAGCTGTTATTGAGGAAGTAGATCGGAGTATCGGGCGTGTGGTA
GAACATTTAAAAGAAAAAGGTGTGCTGGATAATACCCTGATTATCCTCCTTTCGGACAATGGTGGAAATGGAGAACCGGG
CATAGAAGGACGCTTTGCTGGAAAGAATCCCGGTTCAGCGGGGAGTACAGTTTTTCTGGGTGCTGCCTGGGCAGACGTTG
CTAATGCACCATTCTTCTTGTACAAACATCACGGTCATGAAGGAGGTTGCAACACACCGTTTATTGTTTCCTATCCGAAT
GGAATTGATAAAAGTCTGAACGGCACTATTCAAAAAGACAATTACGGACATATAGTAGATATCATGCCTACTTTGGTGAA
ACTTACAGGCGCTACTTATCCCTCTTCGCGTGGCGGCCATAAAGTACCTCCAATGGAAGGTATATCCTTACTGCCTTTAT
TAAAGGGAGAACCGGTAAAGCAAACCAAACCGACCATTGTGGAACACGAAGGCAACAAAATGCTGCGTGACGGAGAATGG
AAAATAGTGCAGGAATATAAAGAGCCGAAATGGAGGCTATACAACTTGAAGAATGATCCTACTGAAATGCGGAATCTCGC
AGATAGGGAGCCTGAAATACTGAACCGAATGATTCATGATTACCAAAAAATGGCAGATCATATCGGAGTAGAAAGTGAGA
TCGAATTCAAGGTTGGCAAATGGTATACTCCTGTAGAAGAATATCTCAAATAA

Upstream 100 bases:

>100_bases
TCCGGATATCCTTAAACAGTTATCGGACAAATGGGCCGTATGGGCAGCTGAGACAAAAGTTTTAATTCCATTTCCTAATA
ATAAAAAATAATATATAGCC

Downstream 100 bases:

>100_bases
GAAGTATCGGAATTATAATCTTTAATTTATAACATATGAAAAATAAGTATCGTAAACTAGCCGTCATCATGCTGACTGCT
GTATGTTTCGCGGGGTGTCA

Product: arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MKRIDYTFMLTLGASIGACPVLAQQNVSKPNIVLILLDDVGYSDFGCYGSEINTPNIDRLAENGIRLRHFYNQARSAPTR
ASLITGLYPHQVGNGALGKVPGYPAYQGYPNENNVFLPEALKTAGYFNVMTGKWHLGYFQGVTPISRGFDRSLNAPFGGY
YFSSDKSLKKNKKERTNQRNLYLNDEEIGFDDDRLPENWYSTHLWTDFGLKFIDEAIEEKQPFFWYLAHNAAHFPLQAPV
ETINKYKGKYMKGWEDVRNARFKKQLELGLFERPDQLTPRNPKVPEWDSLTQEEKERYDMQMAIYAAVIEEVDRSIGRVV
EHLKEKGVLDNTLIILLSDNGGNGEPGIEGRFAGKNPGSAGSTVFLGAAWADVANAPFFLYKHHGHEGGCNTPFIVSYPN
GIDKSLNGTIQKDNYGHIVDIMPTLVKLTGATYPSSRGGHKVPPMEGISLLPLLKGEPVKQTKPTIVEHEGNKMLRDGEW
KIVQEYKEPKWRLYNLKNDPTEMRNLADREPEILNRMIHDYQKMADHIGVESEIEFKVGKWYTPVEEYLK

Sequences:

>Translated_550_residues
MKRIDYTFMLTLGASIGACPVLAQQNVSKPNIVLILLDDVGYSDFGCYGSEINTPNIDRLAENGIRLRHFYNQARSAPTR
ASLITGLYPHQVGNGALGKVPGYPAYQGYPNENNVFLPEALKTAGYFNVMTGKWHLGYFQGVTPISRGFDRSLNAPFGGY
YFSSDKSLKKNKKERTNQRNLYLNDEEIGFDDDRLPENWYSTHLWTDFGLKFIDEAIEEKQPFFWYLAHNAAHFPLQAPV
ETINKYKGKYMKGWEDVRNARFKKQLELGLFERPDQLTPRNPKVPEWDSLTQEEKERYDMQMAIYAAVIEEVDRSIGRVV
EHLKEKGVLDNTLIILLSDNGGNGEPGIEGRFAGKNPGSAGSTVFLGAAWADVANAPFFLYKHHGHEGGCNTPFIVSYPN
GIDKSLNGTIQKDNYGHIVDIMPTLVKLTGATYPSSRGGHKVPPMEGISLLPLLKGEPVKQTKPTIVEHEGNKMLRDGEW
KIVQEYKEPKWRLYNLKNDPTEMRNLADREPEILNRMIHDYQKMADHIGVESEIEFKVGKWYTPVEEYLK
>Mature_550_residues
MKRIDYTFMLTLGASIGACPVLAQQNVSKPNIVLILLDDVGYSDFGCYGSEINTPNIDRLAENGIRLRHFYNQARSAPTR
ASLITGLYPHQVGNGALGKVPGYPAYQGYPNENNVFLPEALKTAGYFNVMTGKWHLGYFQGVTPISRGFDRSLNAPFGGY
YFSSDKSLKKNKKERTNQRNLYLNDEEIGFDDDRLPENWYSTHLWTDFGLKFIDEAIEEKQPFFWYLAHNAAHFPLQAPV
ETINKYKGKYMKGWEDVRNARFKKQLELGLFERPDQLTPRNPKVPEWDSLTQEEKERYDMQMAIYAAVIEEVDRSIGRVV
EHLKEKGVLDNTLIILLSDNGGNGEPGIEGRFAGKNPGSAGSTVFLGAAWADVANAPFFLYKHHGHEGGCNTPFIVSYPN
GIDKSLNGTIQKDNYGHIVDIMPTLVKLTGATYPSSRGGHKVPPMEGISLLPLLKGEPVKQTKPTIVEHEGNKMLRDGEW
KIVQEYKEPKWRLYNLKNDPTEMRNLADREPEILNRMIHDYQKMADHIGVESEIEFKVGKWYTPVEEYLK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI109389362, Length=408, Percent_Identity=28.6764705882353, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI38569407, Length=402, Percent_Identity=28.3582089552239, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI38569405, Length=402, Percent_Identity=28.3582089552239, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI4503899, Length=444, Percent_Identity=27.7027027027027, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI59797060, Length=539, Percent_Identity=24.6753246753247, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI53831991, Length=479, Percent_Identity=26.3048016701461, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI31742482, Length=499, Percent_Identity=24.6492985971944, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI146229331, Length=447, Percent_Identity=25.0559284116331, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI146229329, Length=447, Percent_Identity=25.0559284116331, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI6005990, Length=447, Percent_Identity=25.0559284116331, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI146229324, Length=447, Percent_Identity=25.0559284116331, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI58743319, Length=342, Percent_Identity=25.1461988304094, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI45430057, Length=428, Percent_Identity=25.2336448598131, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI157266309, Length=146, Percent_Identity=38.3561643835616, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI71852586, Length=131, Percent_Identity=41.9847328244275, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI71852584, Length=146, Percent_Identity=40.4109589041096, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI5360208, Length=331, Percent_Identity=25.3776435045317, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4557659, Length=356, Percent_Identity=24.7191011235955, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081924, Length=492, Percent_Identity=23.1707317073171, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790233, Length=443, Percent_Identity=24.8306997742664, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790112, Length=510, Percent_Identity=25.0980392156863, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115533416, Length=521, Percent_Identity=26.8714011516315, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI115533418, Length=502, Percent_Identity=26.4940239043825, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17559078, Length=215, Percent_Identity=28.3720930232558, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281363223, Length=465, Percent_Identity=27.5268817204301, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24666175, Length=451, Percent_Identity=29.0465631929047, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24666109, Length=474, Percent_Identity=27.6371308016878, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI281366397, Length=346, Percent_Identity=30.0578034682081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281366395, Length=346, Percent_Identity=30.0578034682081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24666163, Length=346, Percent_Identity=30.0578034682081, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 62410; Mature: 62410

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIDYTFMLTLGASIGACPVLAQQNVSKPNIVLILLDDVGYSDFGCYGSEINTPNIDRL
CCCCCEEEEEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHH
AENGIRLRHFYNQARSAPTRASLITGLYPHQVGNGALGKVPGYPAYQGYPNENNVFLPEA
HHCCCHHHHHHHHHHCCCCHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEECHHH
LKTAGYFNVMTGKWHLGYFQGVTPISRGFDRSLNAPFGGYYFSSDKSLKKNKKERTNQRN
HHHCCCEEEEECCEECHHHCCCCHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCC
LYLNDEEIGFDDDRLPENWYSTHLWTDFGLKFIDEAIEEKQPFFWYLAHNAAHFPLQAPV
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHH
ETINKYKGKYMKGWEDVRNARFKKQLELGLFERPDQLTPRNPKVPEWDSLTQEEKERYDM
HHHHHHCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
QMAIYAAVIEEVDRSIGRVVEHLKEKGVLDNTLIILLSDNGGNGEPGIEGRFAGKNPGSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCEECCCCCCCC
GSTVFLGAAWADVANAPFFLYKHHGHEGGCNTPFIVSYPNGIDKSLNGTIQKDNYGHIVD
CCEEEEEEHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCEECCCCCCHHH
IMPTLVKLTGATYPSSRGGHKVPPMEGISLLPLLKGEPVKQTKPTIVEHEGNKMLRDGEW
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCEECCCH
KIVQEYKEPKWRLYNLKNDPTEMRNLADREPEILNRMIHDYQKMADHIGVESEIEFKVGK
HHHHHHCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
WYTPVEEYLK
EECCHHHHCC
>Mature Secondary Structure
MKRIDYTFMLTLGASIGACPVLAQQNVSKPNIVLILLDDVGYSDFGCYGSEINTPNIDRL
CCCCCEEEEEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHH
AENGIRLRHFYNQARSAPTRASLITGLYPHQVGNGALGKVPGYPAYQGYPNENNVFLPEA
HHCCCHHHHHHHHHHCCCCHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEECHHH
LKTAGYFNVMTGKWHLGYFQGVTPISRGFDRSLNAPFGGYYFSSDKSLKKNKKERTNQRN
HHHCCCEEEEECCEECHHHCCCCHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCC
LYLNDEEIGFDDDRLPENWYSTHLWTDFGLKFIDEAIEEKQPFFWYLAHNAAHFPLQAPV
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHH
ETINKYKGKYMKGWEDVRNARFKKQLELGLFERPDQLTPRNPKVPEWDSLTQEEKERYDM
HHHHHHCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
QMAIYAAVIEEVDRSIGRVVEHLKEKGVLDNTLIILLSDNGGNGEPGIEGRFAGKNPGSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCEECCCCCCCC
GSTVFLGAAWADVANAPFFLYKHHGHEGGCNTPFIVSYPNGIDKSLNGTIQKDNYGHIVD
CCEEEEEEHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCEECCCCCCHHH
IMPTLVKLTGATYPSSRGGHKVPPMEGISLLPLLKGEPVKQTKPTIVEHEGNKMLRDGEW
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCEECCCH
KIVQEYKEPKWRLYNLKNDPTEMRNLADREPEILNRMIHDYQKMADHIGVESEIEFKVGK
HHHHHHCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
WYTPVEEYLK
EECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]