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The map label for this gene is atsA [H]

Identifier: 29348516

GI number: 29348516

Start: 3952176

End: 3953795

Strand: Reverse

Name: atsA [H]

Synonym: BT_3107

Alternate gene names: 29348516

Gene position: 3953795-3952176 (Counterclockwise)

Preceding gene: 29348517

Following gene: 29348515

Centisome position: 63.16

GC content: 41.05

Gene sequence:

>1620_bases
ATGATGGATGGTAATTTTATATCTCGAAAAAGAATAGGAGGCATAGTTGCTTTATCCTTTTTACAGTTTGGAAATCTCTC
GGGACAAGAGCGTCCGAACATAGTTATGATATTGGCAGATGATATGGGTTATTCCGATATCGGATGTTATGGTAGCGAGA
TAGAAACCCCGCATATTGATAGTTTGGCGTTACAGGGAATCCGGCTGACTCAATTTTATAATACTTCTCGTTCCTGCCCA
ACCCGGGCAAGTCTTATGACTGGTTTGTATCAACATCAAGCTGGGATAGGATGGATGTCAGAAGATCCTTTTAAAAATGT
CGATAAAGATCCGAAAGACTGGGGTGTTGCTGAATATAGGGGGGCTTTGAACCGTAATTGTGTGACTATTGCCGAAGTTC
TTAAAAGTTCAGGTTACCATACCTATATGACGGGCAAATGGCATTTAGGGATGCATGGCATGGAAAAATGGCCTTTGCAG
CGTGGTTTTGAACGTTTTTATGGTATATTGGCAGGGGCTTGCAGTTATCTGAGGCCAGAAGGTGAAAGAGGATTGGTCCT
AGACAACGAAAAGTTACCTGCACCCGAGGCACCTTATTATACTACCGATGCGTTTACAGACTATGCCGTTAATTTTATAA
ATGAACAAAAAGATAATACTCCCTTTTTCTTATATTTAGCATATAATGCTCCGCATTGGCCTTTACAAGCTAAAGAAGCA
GATATAGAGAAATATTATGAACTGTATCGTACGAAAGGCTGGGACCAGATTCGTAAAGAACGCCATAAACGTATGGCCGA
TTTAGGAATAATCGACTCAGAGATCGGTTTTGCTGAATGGGAGAATCGTCAGTGGGAAGAGCTCTCTGAAGCAGAAAAAG
ATCATACAGCTTATAGAATGGCTGTTTATGCTGCACAAGTGCATTGTATGGATTATAACATAGGAAAACTGATTGAGAGC
CTGAAAAAGAGTGGAAAGTTGGATAATACTTTGATCTTTTTCATGTCTGATAACGGGGCATGTGCCGAACCGCATAATGA
ACTTGGTGGTGGCAAGCAAAAAGATATCAATAATCCGGCGGTAAGCGGCCATCCTTCGTATGGCAAAGCTTGGGCTCAGA
CCTCAAATACTCCATTCAGAAAGTACAAACAACGTGCATACGAAGGGGGAATATCTACTCCGTTGATAATTACATGGAAA
AATCGTTTGAAAGGTTTTGAAAATACATGGTGCCACGTTCCCGGATATCTTCCGGATATCATGCCGACCATACTGAATGT
AACTGGTGCCACATATCCTTCTACCTTTCACAATGGTAATAAGATACATCCTTTAGTGGGCACTGATCTTATGCCGGCTA
TAAAAGGAAAAGTTTCTTCCATTCATGAATATATGTATTGGGAACATCAGGGTAATAGAGCTGTCCGTTGGAAAAACTGG
AAAGCGGTATGGGATCAGGAAGGAAAAGTTTGGGAATTATATGATATCGGGAAAGACCGCGTGGAGGCTTGTGATTTGTC
AGCCGTTCATCCGGATATCCTTAAACAGTTATCGGACAAATGGGCCGTATGGGCAGCTGAGACAAAAGTTTTAATTCCAT
TTCCTAATAATAAAAAATAA

Upstream 100 bases:

>100_bases
TCTTAAAAAAGGAAAATGACGTATATAGTATAACGATTGATAAAGAAAATGTTATCAAGCCAATGTGGAAATAATAGAAG
TATATAAAACAATATGTATT

Downstream 100 bases:

>100_bases
TATATAGCCATGAAAAGAATAGATTATACTTTTATGTTGACCCTTGGTGCGTCAATAGGTGCTTGTCCTGTATTGGCCCA
GCAGAATGTATCAAAACCTA

Product: arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MMDGNFISRKRIGGIVALSFLQFGNLSGQERPNIVMILADDMGYSDIGCYGSEIETPHIDSLALQGIRLTQFYNTSRSCP
TRASLMTGLYQHQAGIGWMSEDPFKNVDKDPKDWGVAEYRGALNRNCVTIAEVLKSSGYHTYMTGKWHLGMHGMEKWPLQ
RGFERFYGILAGACSYLRPEGERGLVLDNEKLPAPEAPYYTTDAFTDYAVNFINEQKDNTPFFLYLAYNAPHWPLQAKEA
DIEKYYELYRTKGWDQIRKERHKRMADLGIIDSEIGFAEWENRQWEELSEAEKDHTAYRMAVYAAQVHCMDYNIGKLIES
LKKSGKLDNTLIFFMSDNGACAEPHNELGGGKQKDINNPAVSGHPSYGKAWAQTSNTPFRKYKQRAYEGGISTPLIITWK
NRLKGFENTWCHVPGYLPDIMPTILNVTGATYPSTFHNGNKIHPLVGTDLMPAIKGKVSSIHEYMYWEHQGNRAVRWKNW
KAVWDQEGKVWELYDIGKDRVEACDLSAVHPDILKQLSDKWAVWAAETKVLIPFPNNKK

Sequences:

>Translated_539_residues
MMDGNFISRKRIGGIVALSFLQFGNLSGQERPNIVMILADDMGYSDIGCYGSEIETPHIDSLALQGIRLTQFYNTSRSCP
TRASLMTGLYQHQAGIGWMSEDPFKNVDKDPKDWGVAEYRGALNRNCVTIAEVLKSSGYHTYMTGKWHLGMHGMEKWPLQ
RGFERFYGILAGACSYLRPEGERGLVLDNEKLPAPEAPYYTTDAFTDYAVNFINEQKDNTPFFLYLAYNAPHWPLQAKEA
DIEKYYELYRTKGWDQIRKERHKRMADLGIIDSEIGFAEWENRQWEELSEAEKDHTAYRMAVYAAQVHCMDYNIGKLIES
LKKSGKLDNTLIFFMSDNGACAEPHNELGGGKQKDINNPAVSGHPSYGKAWAQTSNTPFRKYKQRAYEGGISTPLIITWK
NRLKGFENTWCHVPGYLPDIMPTILNVTGATYPSTFHNGNKIHPLVGTDLMPAIKGKVSSIHEYMYWEHQGNRAVRWKNW
KAVWDQEGKVWELYDIGKDRVEACDLSAVHPDILKQLSDKWAVWAAETKVLIPFPNNKK
>Mature_539_residues
MMDGNFISRKRIGGIVALSFLQFGNLSGQERPNIVMILADDMGYSDIGCYGSEIETPHIDSLALQGIRLTQFYNTSRSCP
TRASLMTGLYQHQAGIGWMSEDPFKNVDKDPKDWGVAEYRGALNRNCVTIAEVLKSSGYHTYMTGKWHLGMHGMEKWPLQ
RGFERFYGILAGACSYLRPEGERGLVLDNEKLPAPEAPYYTTDAFTDYAVNFINEQKDNTPFFLYLAYNAPHWPLQAKEA
DIEKYYELYRTKGWDQIRKERHKRMADLGIIDSEIGFAEWENRQWEELSEAEKDHTAYRMAVYAAQVHCMDYNIGKLIES
LKKSGKLDNTLIFFMSDNGACAEPHNELGGGKQKDINNPAVSGHPSYGKAWAQTSNTPFRKYKQRAYEGGISTPLIITWK
NRLKGFENTWCHVPGYLPDIMPTILNVTGATYPSTFHNGNKIHPLVGTDLMPAIKGKVSSIHEYMYWEHQGNRAVRWKNW
KAVWDQEGKVWELYDIGKDRVEACDLSAVHPDILKQLSDKWAVWAAETKVLIPFPNNKK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI38569405, Length=567, Percent_Identity=26.4550264550265, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI38569407, Length=436, Percent_Identity=27.5229357798165, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI59797060, Length=558, Percent_Identity=25.9856630824373, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI53831991, Length=505, Percent_Identity=27.1287128712871, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI109389362, Length=562, Percent_Identity=25.4448398576512, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI146229331, Length=516, Percent_Identity=25.968992248062, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI146229329, Length=516, Percent_Identity=25.968992248062, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI6005990, Length=516, Percent_Identity=25.968992248062, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI146229324, Length=516, Percent_Identity=25.968992248062, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI31742482, Length=491, Percent_Identity=25.4582484725051, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4503899, Length=521, Percent_Identity=24.7600767754319, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI58743319, Length=535, Percent_Identity=25.0467289719626, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI45430057, Length=539, Percent_Identity=25.0463821892393, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI157266309, Length=156, Percent_Identity=38.4615384615385, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI71852586, Length=159, Percent_Identity=35.8490566037736, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI71852584, Length=159, Percent_Identity=35.8490566037736, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI87081924, Length=594, Percent_Identity=22.5589225589226, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790233, Length=451, Percent_Identity=26.6075388026608, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790112, Length=340, Percent_Identity=26.7647058823529, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533416, Length=534, Percent_Identity=24.5318352059925, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI115533418, Length=523, Percent_Identity=24.4741873804971, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17559078, Length=142, Percent_Identity=35.9154929577465, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666175, Length=460, Percent_Identity=27.8260869565217, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281366397, Length=466, Percent_Identity=25.9656652360515, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281366395, Length=466, Percent_Identity=25.9656652360515, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24666163, Length=466, Percent_Identity=25.9656652360515, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24666109, Length=451, Percent_Identity=26.8292682926829, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281363223, Length=411, Percent_Identity=27.9805352798054, Blast_Score=129, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 61504; Mature: 61504

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDGNFISRKRIGGIVALSFLQFGNLSGQERPNIVMILADDMGYSDIGCYGSEIETPHID
CCCCCCCCHHHHCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
SLALQGIRLTQFYNTSRSCPTRASLMTGLYQHQAGIGWMSEDPFKNVDKDPKDWGVAEYR
HHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
GALNRNCVTIAEVLKSSGYHTYMTGKWHLGMHGMEKWPLQRGFERFYGILAGACSYLRPE
HHCCCCHHHHHHHHHCCCCEEEEECEEEECCCCCHHCHHHHHHHHHHHHHHHHHHHHCCC
GERGLVLDNEKLPAPEAPYYTTDAFTDYAVNFINEQKDNTPFFLYLAYNAPHWPLQAKEA
CCCCEEECCCCCCCCCCCCEECCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHH
DIEKYYELYRTKGWDQIRKERHKRMADLGIIDSEIGFAEWENRQWEELSEAEKDHTAYRM
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
AVYAAQVHCMDYNIGKLIESLKKSGKLDNTLIFFMSDNGACAEPHNELGGGKQKDINNPA
HEEEEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCCCCCC
VSGHPSYGKAWAQTSNTPFRKYKQRAYEGGISTPLIITWKNRLKGFENTWCHVPGYLPDI
CCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCEEECCCCCHHH
MPTILNVTGATYPSTFHNGNKIHPLVGTDLMPAIKGKVSSIHEYMYWEHQGNRAVRWKNW
HHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCEEEEECCC
KAVWDQEGKVWELYDIGKDRVEACDLSAVHPDILKQLSDKWAVWAAETKVLIPFPNNKK
CEEECCCCCEEEEEECCCHHHHHCCCCCCCHHHHHHHHHCEEEEEECCEEEEECCCCCC
>Mature Secondary Structure
MMDGNFISRKRIGGIVALSFLQFGNLSGQERPNIVMILADDMGYSDIGCYGSEIETPHID
CCCCCCCCHHHHCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
SLALQGIRLTQFYNTSRSCPTRASLMTGLYQHQAGIGWMSEDPFKNVDKDPKDWGVAEYR
HHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
GALNRNCVTIAEVLKSSGYHTYMTGKWHLGMHGMEKWPLQRGFERFYGILAGACSYLRPE
HHCCCCHHHHHHHHHCCCCEEEEECEEEECCCCCHHCHHHHHHHHHHHHHHHHHHHHCCC
GERGLVLDNEKLPAPEAPYYTTDAFTDYAVNFINEQKDNTPFFLYLAYNAPHWPLQAKEA
CCCCEEECCCCCCCCCCCCEECCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHH
DIEKYYELYRTKGWDQIRKERHKRMADLGIIDSEIGFAEWENRQWEELSEAEKDHTAYRM
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
AVYAAQVHCMDYNIGKLIESLKKSGKLDNTLIFFMSDNGACAEPHNELGGGKQKDINNPA
HEEEEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCCCCCC
VSGHPSYGKAWAQTSNTPFRKYKQRAYEGGISTPLIITWKNRLKGFENTWCHVPGYLPDI
CCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCEEECCCCCHHH
MPTILNVTGATYPSTFHNGNKIHPLVGTDLMPAIKGKVSSIHEYMYWEHQGNRAVRWKNW
HHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCEEEEECCC
KAVWDQEGKVWELYDIGKDRVEACDLSAVHPDILKQLSDKWAVWAAETKVLIPFPNNKK
CEEECCCCCEEEEEECCCHHHHHCCCCCCCHHHHHHHHHCEEEEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]