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The map label for this gene is trxA [C]

Identifier: 29348478

GI number: 29348478

Start: 3892910

End: 3894160

Strand: Reverse

Name: trxA [C]

Synonym: BT_3069

Alternate gene names: 29348478

Gene position: 3894160-3892910 (Counterclockwise)

Preceding gene: 29348479

Following gene: 29348474

Centisome position: 62.2

GC content: 45.88

Gene sequence:

>1251_bases
ATGAAACGACATTTTTGGGCATTCATGGCAATAGTATGCCTGTTAGCCGTCCAGAACACACAAGGACAACAAATGGTTCC
TGCACAGAAAATCTCCGCAACACCTGCCGCCGGCGCACAAATGACTCTTGCGCAAGCTGATGGGATTGCTTTTCGTGAAC
TTTCTTTTCCGGAGGCTTTAAAAAGAGCGGAGGTGGAAGACAAACTTCTTTTTGTCGACTGCTTCACGACTTGGTGCGGT
CCTTGCAAGAGGTTATCCAAAGTGGTTTTTAAAGATTCCTTGGTTGCCGATTATTTTAACCGTCATTTTGTGAATCTGAA
GATGGACATGGAGAAAGGTGAAGGAGTGGAACTCAGAAAGAAATATGGGGTACACGCATATCCTACCCTTCTTTTCATTA
ATTCAAGCGGTGAGGTCGTATACCGACTGGTAGGTGCTGAGGATGCTCCTGAATTGCTGAAGAAAGTGAAACTGGGTGTA
GAGTCCGGTGGACTTTCGGGACTTAAGAAACGTTATGAAGCTGGTGACCGTGATTTGGCTTTTATCTGCGGATATATCAA
TGCGCTTTCTGCTGCCAACCGTGAACAGGAGGCAGGAAAGGTGGCAGCTGATTTCTTGCAGGGAAGTGAGCAGAAAATGC
TGGAAGATGAAGATTACTTCTTGGTATTCTATTACTATGTGCATGATGTCAACTCTTCCGCATTTCAGTATGCGGTAAAC
CATAAGAAAGAAATTACTGATAAATTTCCCCGTCAGGCCGCTTCTCTCGACCGCAGACTGCTCGAAGACTGGATAGCCGG
TTCATATGCCTACCTGAAAGTGGACGAGTCCAATCACTGTACATTTGATGAGCAGGGACTGGATGCCTACGTGGCGAAGA
TGAAACAGATGAATGTGGCGGAAGCTGACATGATAGGCGAGAGTCTGCGCCTCAGCAGAGACGGTATAATGAAGCAATGG
GATTCATTTGTGAAACGTGGCGATAAGATACTTGCTTCGCACACCATTTTGGGTGACGAAGGGCATTTATTGCAATGGGT
GAACTGGCTCAATAAGGAATGTGCAGATATGTCATTGCGTGAGAAAGCTGCTCAGTGGTGTGATAAAGCCTGCGAAGAAT
TGATAAAGAAGAATGAGGAGATCAAAAAGAACTTGCCTCCCGGAGCTATTCCGGCCATCTCCATGGTAGACCATAAAGGG
CAGTTACTACAAGTGGCAGAGAAGCTGAGAAAACTGATGCAACAAAGTTGA

Upstream 100 bases:

>100_bases
CAATTCTCTTTGAACTGGAAATGAAGGGAGCCGTACGGGTATTGGCAGGAGGAGTTTATCAATTATTATAAATCTAATAA
CCAACCTAAAACAATTTGAA

Downstream 100 bases:

>100_bases
GACCCTGTAGGGATTCATAAATAAGAGTGTGAATTCTAAGTCCTCTCCAAACAATATCTATAAAATCTTACCCAAGTTTA
CGAACATTAACGTATCCTTG

Product: putative disulphide-isomerase

Products: NA

Alternate protein names: Thioredoxin DomaiN-Containing Protein; Disulfide-Isomerase; Disulphide-Isomerase; Thioredoxin Domain; Thiol-Disulfide Interchange Like Protein; Thiol-Disulfide Interchange Protein DsbD-Like Protein; ThiolDisulfide Interchange Protein; Thioredoxin; Thioredoxin-Related Protein-Like Protein

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKRHFWAFMAIVCLLAVQNTQGQQMVPAQKISATPAAGAQMTLAQADGIAFRELSFPEALKRAEVEDKLLFVDCFTTWCG
PCKRLSKVVFKDSLVADYFNRHFVNLKMDMEKGEGVELRKKYGVHAYPTLLFINSSGEVVYRLVGAEDAPELLKKVKLGV
ESGGLSGLKKRYEAGDRDLAFICGYINALSAANREQEAGKVAADFLQGSEQKMLEDEDYFLVFYYYVHDVNSSAFQYAVN
HKKEITDKFPRQAASLDRRLLEDWIAGSYAYLKVDESNHCTFDEQGLDAYVAKMKQMNVAEADMIGESLRLSRDGIMKQW
DSFVKRGDKILASHTILGDEGHLLQWVNWLNKECADMSLREKAAQWCDKACEELIKKNEEIKKNLPPGAIPAISMVDHKG
QLLQVAEKLRKLMQQS

Sequences:

>Translated_416_residues
MKRHFWAFMAIVCLLAVQNTQGQQMVPAQKISATPAAGAQMTLAQADGIAFRELSFPEALKRAEVEDKLLFVDCFTTWCG
PCKRLSKVVFKDSLVADYFNRHFVNLKMDMEKGEGVELRKKYGVHAYPTLLFINSSGEVVYRLVGAEDAPELLKKVKLGV
ESGGLSGLKKRYEAGDRDLAFICGYINALSAANREQEAGKVAADFLQGSEQKMLEDEDYFLVFYYYVHDVNSSAFQYAVN
HKKEITDKFPRQAASLDRRLLEDWIAGSYAYLKVDESNHCTFDEQGLDAYVAKMKQMNVAEADMIGESLRLSRDGIMKQW
DSFVKRGDKILASHTILGDEGHLLQWVNWLNKECADMSLREKAAQWCDKACEELIKKNEEIKKNLPPGAIPAISMVDHKG
QLLQVAEKLRKLMQQS
>Mature_416_residues
MKRHFWAFMAIVCLLAVQNTQGQQMVPAQKISATPAAGAQMTLAQADGIAFRELSFPEALKRAEVEDKLLFVDCFTTWCG
PCKRLSKVVFKDSLVADYFNRHFVNLKMDMEKGEGVELRKKYGVHAYPTLLFINSSGEVVYRLVGAEDAPELLKKVKLGV
ESGGLSGLKKRYEAGDRDLAFICGYINALSAANREQEAGKVAADFLQGSEQKMLEDEDYFLVFYYYVHDVNSSAFQYAVN
HKKEITDKFPRQAASLDRRLLEDWIAGSYAYLKVDESNHCTFDEQGLDAYVAKMKQMNVAEADMIGESLRLSRDGIMKQW
DSFVKRGDKILASHTILGDEGHLLQWVNWLNKECADMSLREKAAQWCDKACEELIKKNEEIKKNLPPGAIPAISMVDHKG
QLLQVAEKLRKLMQQS

Specific function: Participates In Various Redox Reactions Through The Reversible Oxidation Of Its Active Center Dithiol To A Disulfide And Catalyzes Dithiol-Disulfide Exchange Reactions. [C]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46996; Mature: 46996

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHFWAFMAIVCLLAVQNTQGQQMVPAQKISATPAAGAQMTLAQADGIAFRELSFPEAL
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCEEECCCCHHHH
KRAEVEDKLLFVDCFTTWCGPCKRLSKVVFKDSLVADYFNRHFVNLKMDMEKGEGVELRK
HHCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHH
KYGVHAYPTLLFINSSGEVVYRLVGAEDAPELLKKVKLGVESGGLSGLKKRYEAGDRDLA
HCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHH
FICGYINALSAANREQEAGKVAADFLQGSEQKMLEDEDYFLVFYYYVHDVNSSAFQYAVN
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEEEEECCCCHHHHHHHH
HKKEITDKFPRQAASLDRRLLEDWIAGSYAYLKVDESNHCTFDEQGLDAYVAKMKQMNVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCHH
EADMIGESLRLSRDGIMKQWDSFVKRGDKILASHTILGDEGHLLQWVNWLNKECADMSLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHEEEECCCCHHHHHHHHHHHHHHCHHHH
EKAAQWCDKACEELIKKNEEIKKNLPPGAIPAISMVDHKGQLLQVAEKLRKLMQQS
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRHFWAFMAIVCLLAVQNTQGQQMVPAQKISATPAAGAQMTLAQADGIAFRELSFPEAL
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCEEECCCCHHHH
KRAEVEDKLLFVDCFTTWCGPCKRLSKVVFKDSLVADYFNRHFVNLKMDMEKGEGVELRK
HHCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHH
KYGVHAYPTLLFINSSGEVVYRLVGAEDAPELLKKVKLGVESGGLSGLKKRYEAGDRDLA
HCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHH
FICGYINALSAANREQEAGKVAADFLQGSEQKMLEDEDYFLVFYYYVHDVNSSAFQYAVN
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEEEEECCCCHHHHHHHH
HKKEITDKFPRQAASLDRRLLEDWIAGSYAYLKVDESNHCTFDEQGLDAYVAKMKQMNVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCHH
EADMIGESLRLSRDGIMKQWDSFVKRGDKILASHTILGDEGHLLQWVNWLNKECADMSLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHEEEECCCCHHHHHHHHHHHHHHCHHHH
EKAAQWCDKACEELIKKNEEIKKNLPPGAIPAISMVDHKGQLLQVAEKLRKLMQQS
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA