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The map label for this gene is resE [H]

Identifier: 29348380

GI number: 29348380

Start: 3747864

End: 3751904

Strand: Reverse

Name: resE [H]

Synonym: BT_2971

Alternate gene names: 29348380

Gene position: 3751904-3747864 (Counterclockwise)

Preceding gene: 29348384

Following gene: 29348379

Centisome position: 59.93

GC content: 40.26

Gene sequence:

>4041_bases
ATGTGGCGAAGAACAATAACCTTTCTCTTAAGTCTTTTATCTATGGTGATGGCGGAAGCCACTAATCATTATTTTAAGCA
TTTGGGAGTATCTGATGGATTATCTCAGGTGTGTATCCCATCAATTTATCAGGATGAGTTAGGGGCAGTCTGGCTGGGAA
CTACTGAGGGACTGAATAGATACAACGGTAAGGATGTAAAAGTATTCCAGCCTTCGGAAAGTAATCATGGACTGACTAAT
AATGAGATTAACGAATTATGTGGAGATAAAAACGGAAGAATGTATATTCGTTCGGGAAACGATCTGATTAAACTGGATAT
TTATACGGAGCAATTCACTTGTTTGCGACAGAAAGGTGTGTATGGACTGTTTTGTAAGAAAGATACACTTTGGGTGAGTT
GTGCAGACGGCATTTATTATTATACGGGACAGGGTACAGAGCTGACATTCTTTGCTCGTGTGCAGAAAGGTTTTGTGGGG
AGAGCACTCTATGTAGACAAAGAGACTGTATGGGTGGTTACCAGAAAATACTTGGTCGCAATATCACGTGAAGACCCTCT
TCGGCAAGAGATTTTACTTACCCTTGATAAGGGCAATTGTATTTTAGGCGATAGTTCCGGAAATATATGGGTGGGAGCTT
GGAACGGCTTGTACCGTATTTCTCCCAATCGGGAGACAACCGCTTATGTTAGTCATTCGGGAATGGGTGAATTATCCGAT
AATCAGGTCCGATGCGTGCTGGAAGATGATTTTAAGCATATTTGGGTAGGTACGTTCAAGGGAATCGATTGTTACGATCC
GGTTACTGATACGTGGAGTCATTATACGCGTTATGGAAGTTCTTCAAATTCTTTAAGCCATACTTCTATTCTCTCTCTTC
ATAAAGATATGCAAGGTAATATTTGGGTCGGGACTTATTATGGAGGAGTGAATGTATTCAATCCCGATAAGAATAATCAT
AGCTTTTATTGTGCCGAACCTTTACGTGAAGACTGTCTCAGCTTTCCGGTAGTCGGTAAAATGACTGAAGATAGTGCAGG
AAATGTGTGGATCTGTACTGAAGGTGGAGGGCTGAATTGTTATCATGGGGATACTGGCGTTTTCTCCCGATATATGTATC
ATAAAGGAGATCAGGGGACATTAGGGAGTAATAATGTCAAGTCGATCTTTTATAGAAAGGAGAATAATCGATTGTATGCG
GGGACTCATTTAGGAGGATTGTTCGTTCTGGATTTAAAATCGAACAAGGGACACACTCTCCATCATGTTACCGGTGACCC
TGCTTCGTTGCCTCATGAGATTGTGAACGATATTCAGGAGTATAAGGATGGCATTGCGATGTTGACACAAGGTGGTCCGG
TGTTTTTTGATCCGGTGACCGAGAAATTCTCACCGCTTACGGATGATCCGTCTGTCCAGAAATTGATCAGTCGGGAATAT
GCTTTTGAAACGTTTCTGATCGATAGCCGGCATCGTATGTGGCTTGCTGTTGGTGGCGGAGGGATAGTGTGCGTCAATTT
ATCTTCTTCAAAAGTGACTCAATATATGGCGGATAGTGAGAAAGACACGTTGACGGTAGGAAGATACAAAACCGTGCATA
TTTTTGAAGATAATAAAGGAGATATTTATTTTAGTACGATTGGCGCGGGGATATTCAAGTATCAGGAGAAACAGGATACT
TTCAAGTCTTACGGAACTACCAATGGAGTACTTCCGAGTAATTATTGTTATTATATCTGCGAGTCTGCCCGGGATAATTG
TCTGCTTGTTTTGCATGGGAAAGGGCTTTCTATCTTTGATCGTGAAAAAGAGGTTACAGAAGAGACTTATCACTTGTTTC
GTCAGACTTATAATTTGGGGTCCGCTTTATATCGAAGCAAAAATGGGATTATTTATATCAGTGGTACCAATGGATTGGCT
ATGTTTCAAGAGCGGTCCTTTTATGAATCTCAGGTCAAAAGCTTCTTGAATTTTGATAAATTGTTTATTTTCAATGACGA
AATAGCTCCTGGTGATGAGTCCGGCATCCTGACTGAGATATTGGCGAAAACGTCGGATATCTTTTTAAGCTATCAACAGA
ATAACGTAACAGTGGAATTTGCTACTTTTAATTATAATAGTGACCGTAATCGTTTGTTTGAATATTATCTGGATGGCTTC
GATAAGGTGTGGACCCAGACTTCGGGCACTACGGTTACTTACACCAATCTGCCTCCTGGAGACTATACGCTCAAAGTTCG
TTCGATGGAAAATAAGGAGAGTTTGAAAGATGCAATCTGCTTGAATATACATGTTTCCGCTCCTTTTTATGCTACCATAT
GGGCATATCTGTTTTATGTCCTTTGTCTGACTGCATTGATGGTCGCATTTGTTCGTTTTAAAACACGGCAGGCGGCTCTG
AGGTCTTCATTGGAGTTTGAGCGAAAAGAAAAAGAGAGGATTGAAGAACTCAATCAAGTAAAATTGCGCTTCTTTACTAA
TATTTCTCATGAATTTCGTACTCCATTAACGCTTATTCTGGGGCAAATTGAAGTATTGATGCAAATGGATTTGGGCACAA
CCGTTTATAATCGTATTCAGCGTATATATAAAAACGCCTGGCATATGCGGAATTTGATCTCCGAGTTGCTCGATTTTCGC
AAACAGGAGCAGGGTTATTTGAAACTCAGAGTTGAAGAACAGAATTTGGTTACTTTTACTCGTCAGATTTATATGTGTTT
TTATGAATATGCACAAAAAAAGGAGATCACATATCGCTTTGATTCTGTAGAGGAAACGATTTCTGTCTGGTTTGATCCAA
TACAGTTACAGAAAGTGATTTTTAATTTATTGTCGAATGCTTTTAAGTATACATCCAATAAGGGAAATATAACTGTAGAA
GTAAGGAAAGTTGCTTCACAGGCCGTAGTTTCAGTGTGTGATACGGGTATTGGGATTCCGGTTGAACATATTTCGAAGAT
ATTCGACCGGTTCTATCAGACGGATAATGCCTCTTCTTCCTCTTCTTTTACTTTGGGGACAGGCATCGGATTGGCGTTGG
CAAAAGGAATTATGAATATGCATCATGGAAAGATTGAGGTAGAAAGTACTGTTGGTGAGGGTACTAAGTTTATCTTGTCT
CTACCTTTAGGAAACCGACATTTCAGTGATGAAGAGATGGCTGTGACGGAAGGTCGGGAGTCACTGATTATTCCGGAAGC
TTCTGTATCTTCTTATGGACAGTTGATGGCGGAAGAGATAAAAGAACCTGAATCGCAGAAAAATATGGATGAAGAAGATA
AGCCTACGATTCTTTTGGTAGATGATAATACCGAACTATTGTCCATGCTGGAAGATATATTCTTACCGATGTATAATGTA
TATACTGCGTGTAATGGACGCGAAGGACTGGAGATGGCGCAACAAATACAACCGGATCTGATAGTAAGTGATGTGATTAT
GCCTGAGATGTCAGGTAAGGACTTGTGCTATAAAATCAAGACCAATGTAGAACTTTCTCATATTTCTGTCGTTCTGTTGA
CAGCACAGACTTCTGTGGAATATGTTGTAGAAGGTTTGATGTTCGGAGCGGATGATTATATAACGAAGCCGTTTAATATA
AAGGTATTGGTGGCCCGTTGCAATAACTTGATAAAAAACAAGAAACGTCTGATTGCACATTATGCGGGTAAGGTCATTAC
GGAATCTCCTGTAGCGGAAGCTATTAATGAGAAAGATAAAGAACTGCTGACGAAATGTGTAAATATTGTCAGAGAGAATT
TTGAGAACCCTGATTTTGATGTTACTGCGCTTGCTTCAGAATTATGTATGGGACGTAGCAAATTATATATGCAGTTTAAA
CAAATGACCGGGTTGACTCCGAATGAGTTCATCTTGAAAGTGAAGCTGGATGAAGCTATGTCTTTGCTGACAGAGCATCC
GGAACTAAATATAACAGAGATTTCCGTTCGGCTCGGCTTTTCTTCTCCCCGTTATTTCAGCAAATCCTTTAAAGCCTTCT
TCGGGATTGCTCCGCAAGGAGTCAGGAGTAGGAAGGAGTAG

Upstream 100 bases:

>100_bases
AAACTGCATTTCGGCTGGAAGGGTATAAATTAAAGAGATTCTTAACCAATAATTATGTTTTTTTTGTATTTTTGCTACCC
GCAATATAATTATGTGTAAA

Downstream 100 bases:

>100_bases
TTGTTTCATTACCTGACTTCTCAAGTATTAATATCCGGCATATCAGCTATTAATATCCGACAATTCAGTTGTTAATACCT
GATATATCAGCTGTTAATAC

Product: two-component system sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1346; Mature: 1346

Protein sequence:

>1346_residues
MWRRTITFLLSLLSMVMAEATNHYFKHLGVSDGLSQVCIPSIYQDELGAVWLGTTEGLNRYNGKDVKVFQPSESNHGLTN
NEINELCGDKNGRMYIRSGNDLIKLDIYTEQFTCLRQKGVYGLFCKKDTLWVSCADGIYYYTGQGTELTFFARVQKGFVG
RALYVDKETVWVVTRKYLVAISREDPLRQEILLTLDKGNCILGDSSGNIWVGAWNGLYRISPNRETTAYVSHSGMGELSD
NQVRCVLEDDFKHIWVGTFKGIDCYDPVTDTWSHYTRYGSSSNSLSHTSILSLHKDMQGNIWVGTYYGGVNVFNPDKNNH
SFYCAEPLREDCLSFPVVGKMTEDSAGNVWICTEGGGLNCYHGDTGVFSRYMYHKGDQGTLGSNNVKSIFYRKENNRLYA
GTHLGGLFVLDLKSNKGHTLHHVTGDPASLPHEIVNDIQEYKDGIAMLTQGGPVFFDPVTEKFSPLTDDPSVQKLISREY
AFETFLIDSRHRMWLAVGGGGIVCVNLSSSKVTQYMADSEKDTLTVGRYKTVHIFEDNKGDIYFSTIGAGIFKYQEKQDT
FKSYGTTNGVLPSNYCYYICESARDNCLLVLHGKGLSIFDREKEVTEETYHLFRQTYNLGSALYRSKNGIIYISGTNGLA
MFQERSFYESQVKSFLNFDKLFIFNDEIAPGDESGILTEILAKTSDIFLSYQQNNVTVEFATFNYNSDRNRLFEYYLDGF
DKVWTQTSGTTVTYTNLPPGDYTLKVRSMENKESLKDAICLNIHVSAPFYATIWAYLFYVLCLTALMVAFVRFKTRQAAL
RSSLEFERKEKERIEELNQVKLRFFTNISHEFRTPLTLILGQIEVLMQMDLGTTVYNRIQRIYKNAWHMRNLISELLDFR
KQEQGYLKLRVEEQNLVTFTRQIYMCFYEYAQKKEITYRFDSVEETISVWFDPIQLQKVIFNLLSNAFKYTSNKGNITVE
VRKVASQAVVSVCDTGIGIPVEHISKIFDRFYQTDNASSSSSFTLGTGIGLALAKGIMNMHHGKIEVESTVGEGTKFILS
LPLGNRHFSDEEMAVTEGRESLIIPEASVSSYGQLMAEEIKEPESQKNMDEEDKPTILLVDDNTELLSMLEDIFLPMYNV
YTACNGREGLEMAQQIQPDLIVSDVIMPEMSGKDLCYKIKTNVELSHISVVLLTAQTSVEYVVEGLMFGADDYITKPFNI
KVLVARCNNLIKNKKRLIAHYAGKVITESPVAEAINEKDKELLTKCVNIVRENFENPDFDVTALASELCMGRSKLYMQFK
QMTGLTPNEFILKVKLDEAMSLLTEHPELNITEISVRLGFSSPRYFSKSFKAFFGIAPQGVRSRKE

Sequences:

>Translated_1346_residues
MWRRTITFLLSLLSMVMAEATNHYFKHLGVSDGLSQVCIPSIYQDELGAVWLGTTEGLNRYNGKDVKVFQPSESNHGLTN
NEINELCGDKNGRMYIRSGNDLIKLDIYTEQFTCLRQKGVYGLFCKKDTLWVSCADGIYYYTGQGTELTFFARVQKGFVG
RALYVDKETVWVVTRKYLVAISREDPLRQEILLTLDKGNCILGDSSGNIWVGAWNGLYRISPNRETTAYVSHSGMGELSD
NQVRCVLEDDFKHIWVGTFKGIDCYDPVTDTWSHYTRYGSSSNSLSHTSILSLHKDMQGNIWVGTYYGGVNVFNPDKNNH
SFYCAEPLREDCLSFPVVGKMTEDSAGNVWICTEGGGLNCYHGDTGVFSRYMYHKGDQGTLGSNNVKSIFYRKENNRLYA
GTHLGGLFVLDLKSNKGHTLHHVTGDPASLPHEIVNDIQEYKDGIAMLTQGGPVFFDPVTEKFSPLTDDPSVQKLISREY
AFETFLIDSRHRMWLAVGGGGIVCVNLSSSKVTQYMADSEKDTLTVGRYKTVHIFEDNKGDIYFSTIGAGIFKYQEKQDT
FKSYGTTNGVLPSNYCYYICESARDNCLLVLHGKGLSIFDREKEVTEETYHLFRQTYNLGSALYRSKNGIIYISGTNGLA
MFQERSFYESQVKSFLNFDKLFIFNDEIAPGDESGILTEILAKTSDIFLSYQQNNVTVEFATFNYNSDRNRLFEYYLDGF
DKVWTQTSGTTVTYTNLPPGDYTLKVRSMENKESLKDAICLNIHVSAPFYATIWAYLFYVLCLTALMVAFVRFKTRQAAL
RSSLEFERKEKERIEELNQVKLRFFTNISHEFRTPLTLILGQIEVLMQMDLGTTVYNRIQRIYKNAWHMRNLISELLDFR
KQEQGYLKLRVEEQNLVTFTRQIYMCFYEYAQKKEITYRFDSVEETISVWFDPIQLQKVIFNLLSNAFKYTSNKGNITVE
VRKVASQAVVSVCDTGIGIPVEHISKIFDRFYQTDNASSSSSFTLGTGIGLALAKGIMNMHHGKIEVESTVGEGTKFILS
LPLGNRHFSDEEMAVTEGRESLIIPEASVSSYGQLMAEEIKEPESQKNMDEEDKPTILLVDDNTELLSMLEDIFLPMYNV
YTACNGREGLEMAQQIQPDLIVSDVIMPEMSGKDLCYKIKTNVELSHISVVLLTAQTSVEYVVEGLMFGADDYITKPFNI
KVLVARCNNLIKNKKRLIAHYAGKVITESPVAEAINEKDKELLTKCVNIVRENFENPDFDVTALASELCMGRSKLYMQFK
QMTGLTPNEFILKVKLDEAMSLLTEHPELNITEISVRLGFSSPRYFSKSFKAFFGIAPQGVRSRKE
>Mature_1346_residues
MWRRTITFLLSLLSMVMAEATNHYFKHLGVSDGLSQVCIPSIYQDELGAVWLGTTEGLNRYNGKDVKVFQPSESNHGLTN
NEINELCGDKNGRMYIRSGNDLIKLDIYTEQFTCLRQKGVYGLFCKKDTLWVSCADGIYYYTGQGTELTFFARVQKGFVG
RALYVDKETVWVVTRKYLVAISREDPLRQEILLTLDKGNCILGDSSGNIWVGAWNGLYRISPNRETTAYVSHSGMGELSD
NQVRCVLEDDFKHIWVGTFKGIDCYDPVTDTWSHYTRYGSSSNSLSHTSILSLHKDMQGNIWVGTYYGGVNVFNPDKNNH
SFYCAEPLREDCLSFPVVGKMTEDSAGNVWICTEGGGLNCYHGDTGVFSRYMYHKGDQGTLGSNNVKSIFYRKENNRLYA
GTHLGGLFVLDLKSNKGHTLHHVTGDPASLPHEIVNDIQEYKDGIAMLTQGGPVFFDPVTEKFSPLTDDPSVQKLISREY
AFETFLIDSRHRMWLAVGGGGIVCVNLSSSKVTQYMADSEKDTLTVGRYKTVHIFEDNKGDIYFSTIGAGIFKYQEKQDT
FKSYGTTNGVLPSNYCYYICESARDNCLLVLHGKGLSIFDREKEVTEETYHLFRQTYNLGSALYRSKNGIIYISGTNGLA
MFQERSFYESQVKSFLNFDKLFIFNDEIAPGDESGILTEILAKTSDIFLSYQQNNVTVEFATFNYNSDRNRLFEYYLDGF
DKVWTQTSGTTVTYTNLPPGDYTLKVRSMENKESLKDAICLNIHVSAPFYATIWAYLFYVLCLTALMVAFVRFKTRQAAL
RSSLEFERKEKERIEELNQVKLRFFTNISHEFRTPLTLILGQIEVLMQMDLGTTVYNRIQRIYKNAWHMRNLISELLDFR
KQEQGYLKLRVEEQNLVTFTRQIYMCFYEYAQKKEITYRFDSVEETISVWFDPIQLQKVIFNLLSNAFKYTSNKGNITVE
VRKVASQAVVSVCDTGIGIPVEHISKIFDRFYQTDNASSSSSFTLGTGIGLALAKGIMNMHHGKIEVESTVGEGTKFILS
LPLGNRHFSDEEMAVTEGRESLIIPEASVSSYGQLMAEEIKEPESQKNMDEEDKPTILLVDDNTELLSMLEDIFLPMYNV
YTACNGREGLEMAQQIQPDLIVSDVIMPEMSGKDLCYKIKTNVELSHISVVLLTAQTSVEYVVEGLMFGADDYITKPFNI
KVLVARCNNLIKNKKRLIAHYAGKVITESPVAEAINEKDKELLTKCVNIVRENFENPDFDVTALASELCMGRSKLYMQFK
QMTGLTPNEFILKVKLDEAMSLLTEHPELNITEISVRLGFSSPRYFSKSFKAFFGIAPQGVRSRKE

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=410, Percent_Identity=26.3414634146341, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=31.25, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=6e-29,
Organism=Escherichia coli, GI1788713, Length=424, Percent_Identity=26.8867924528302, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=30.5084745762712, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=263, Percent_Identity=28.1368821292776, Blast_Score=97, Evalue=8e-21,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=24.3478260869565, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=28.3464566929134, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=27.5193798449612, Blast_Score=87, Evalue=9e-18,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=24.8979591836735, Blast_Score=84, Evalue=6e-17,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=26.9709543568465, Blast_Score=81, Evalue=4e-16,
Organism=Escherichia coli, GI1790861, Length=253, Percent_Identity=26.4822134387352, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=25.1063829787234, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1788550, Length=147, Percent_Identity=34.0136054421769, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1788394, Length=126, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=205, Percent_Identity=25.3658536585366, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1790863, Length=118, Percent_Identity=32.2033898305085, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1789808, Length=232, Percent_Identity=25, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 152866; Mature: 152866

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRRTITFLLSLLSMVMAEATNHYFKHLGVSDGLSQVCIPSIYQDELGAVWLGTTEGLNR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHCCCEEEEECCCCCCC
YNGKDVKVFQPSESNHGLTNNEINELCGDKNGRMYIRSGNDLIKLDIYTEQFTCLRQKGV
CCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHHHHHHCCC
YGLFCKKDTLWVSCADGIYYYTGQGTELTFFARVQKGFVGRALYVDKETVWVVTRKYLVA
EEEEEECCEEEEEECCCEEEEECCCCEEEEEEEHHHCCCCEEEEECCCEEEEEEEEEEEE
ISREDPLRQEILLTLDKGNCILGDSSGNIWVGAWNGLYRISPNRETTAYVSHSGMGELSD
ECCCCCCCEEEEEEEECCCEEEECCCCCEEEEECCCEEEECCCCCEEEEEECCCCCCCCC
NQVRCVLEDDFKHIWVGTFKGIDCYDPVTDTWSHYTRYGSSSNSLSHTSILSLHKDMQGN
CCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
IWVGTYYGGVNVFNPDKNNHSFYCAEPLREDCLSFPVVGKMTEDSAGNVWICTEGGGLNC
EEEEEEECCEEEECCCCCCCCEEECCHHHHHHHCCCCCCEECCCCCCCEEEEECCCCEEE
YHGDTGVFSRYMYHKGDQGTLGSNNVKSIFYRKENNRLYAGTHLGGLFVLDLKSNKGHTL
EECCHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCEEEEEEEECCCCCEE
HHVTGDPASLPHEIVNDIQEYKDGIAMLTQGGPVFFDPVTEKFSPLTDDPSVQKLISREY
EEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEECCHHHHCCCCCCCHHHHHHHHHHH
AFETFLIDSRHRMWLAVGGGGIVCVNLSSSKVTQYMADSEKDTLTVGRYKTVHIFEDNKG
HHEEEEEECCCEEEEEECCCCEEEEECCHHHHHHHHHCCCCCEEEECCEEEEEEEECCCC
DIYFSTIGAGIFKYQEKQDTFKSYGTTNGVLPSNYCYYICESARDNCLLVLHGKGLSIFD
CEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCEEC
REKEVTEETYHLFRQTYNLGSALYRSKNGIIYISGTNGLAMFQERSFYESQVKSFLNFDK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCCE
LFIFNDEIAPGDESGILTEILAKTSDIFLSYQQNNVTVEFATFNYNSDRNRLFEYYLDGF
EEEEECCCCCCCCCCHHHHHHHCCCEEEEEEECCCEEEEEEEEECCCCHHHHHHHHHCCH
DKVWTQTSGTTVTYTNLPPGDYTLKVRSMENKESLKDAICLNIHVSAPFYATIWAYLFYV
HHHHCCCCCCEEEECCCCCCCEEEEEECCCCHHHHCCEEEEEEEECCCHHHHHHHHHHHH
LCLTALMVAFVRFKTRQAALRSSLEFERKEKERIEELNQVKLRFFTNISHEFRTPLTLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHH
GQIEVLMQMDLGTTVYNRIQRIYKNAWHMRNLISELLDFRKQEQGYLKLRVEEQNLVTFT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHH
RQIYMCFYEYAQKKEITYRFDSVEETISVWFDPIQLQKVIFNLLSNAFKYTSNKGNITVE
HHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VRKVASQAVVSVCDTGIGIPVEHISKIFDRFYQTDNASSSSSFTLGTGIGLALAKGIMNM
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHH
HHGKIEVESTVGEGTKFILSLPLGNRHFSDEEMAVTEGRESLIIPEASVSSYGQLMAEEI
CCCEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHCCCCEEEECCCCHHHHHHHHHHHH
KEPESQKNMDEEDKPTILLVDDNTELLSMLEDIFLPMYNVYTACNGREGLEMAQQIQPDL
CCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
IVSDVIMPEMSGKDLCYKIKTNVELSHISVVLLTAQTSVEYVVEGLMFGADDYITKPFNI
EEHHHHCCCCCCCCEEEEEECCEEEEEEEEEEEEECCHHHHHHHHHHCCCCHHCCCCCCE
KVLVARCNNLIKNKKRLIAHYAGKVITESPVAEAINEKDKELLTKCVNIVRENFENPDFD
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCH
VTALASELCMGRSKLYMQFKQMTGLTPNEFILKVKLDEAMSLLTEHPELNITEISVRLGF
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCCCEEEEEEEECC
SSPRYFSKSFKAFFGIAPQGVRSRKE
CCCHHHHHHHHHHHCCCCCHHCCCCC
>Mature Secondary Structure
MWRRTITFLLSLLSMVMAEATNHYFKHLGVSDGLSQVCIPSIYQDELGAVWLGTTEGLNR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHCCCEEEEECCCCCCC
YNGKDVKVFQPSESNHGLTNNEINELCGDKNGRMYIRSGNDLIKLDIYTEQFTCLRQKGV
CCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHHHHHHCCC
YGLFCKKDTLWVSCADGIYYYTGQGTELTFFARVQKGFVGRALYVDKETVWVVTRKYLVA
EEEEEECCEEEEEECCCEEEEECCCCEEEEEEEHHHCCCCEEEEECCCEEEEEEEEEEEE
ISREDPLRQEILLTLDKGNCILGDSSGNIWVGAWNGLYRISPNRETTAYVSHSGMGELSD
ECCCCCCCEEEEEEEECCCEEEECCCCCEEEEECCCEEEECCCCCEEEEEECCCCCCCCC
NQVRCVLEDDFKHIWVGTFKGIDCYDPVTDTWSHYTRYGSSSNSLSHTSILSLHKDMQGN
CCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
IWVGTYYGGVNVFNPDKNNHSFYCAEPLREDCLSFPVVGKMTEDSAGNVWICTEGGGLNC
EEEEEEECCEEEECCCCCCCCEEECCHHHHHHHCCCCCCEECCCCCCCEEEEECCCCEEE
YHGDTGVFSRYMYHKGDQGTLGSNNVKSIFYRKENNRLYAGTHLGGLFVLDLKSNKGHTL
EECCHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCEEEEEEEECCCCCEE
HHVTGDPASLPHEIVNDIQEYKDGIAMLTQGGPVFFDPVTEKFSPLTDDPSVQKLISREY
EEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEECCHHHHCCCCCCCHHHHHHHHHHH
AFETFLIDSRHRMWLAVGGGGIVCVNLSSSKVTQYMADSEKDTLTVGRYKTVHIFEDNKG
HHEEEEEECCCEEEEEECCCCEEEEECCHHHHHHHHHCCCCCEEEECCEEEEEEEECCCC
DIYFSTIGAGIFKYQEKQDTFKSYGTTNGVLPSNYCYYICESARDNCLLVLHGKGLSIFD
CEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCEEC
REKEVTEETYHLFRQTYNLGSALYRSKNGIIYISGTNGLAMFQERSFYESQVKSFLNFDK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCCE
LFIFNDEIAPGDESGILTEILAKTSDIFLSYQQNNVTVEFATFNYNSDRNRLFEYYLDGF
EEEEECCCCCCCCCCHHHHHHHCCCEEEEEEECCCEEEEEEEEECCCCHHHHHHHHHCCH
DKVWTQTSGTTVTYTNLPPGDYTLKVRSMENKESLKDAICLNIHVSAPFYATIWAYLFYV
HHHHCCCCCCEEEECCCCCCCEEEEEECCCCHHHHCCEEEEEEEECCCHHHHHHHHHHHH
LCLTALMVAFVRFKTRQAALRSSLEFERKEKERIEELNQVKLRFFTNISHEFRTPLTLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHH
GQIEVLMQMDLGTTVYNRIQRIYKNAWHMRNLISELLDFRKQEQGYLKLRVEEQNLVTFT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHH
RQIYMCFYEYAQKKEITYRFDSVEETISVWFDPIQLQKVIFNLLSNAFKYTSNKGNITVE
HHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VRKVASQAVVSVCDTGIGIPVEHISKIFDRFYQTDNASSSSSFTLGTGIGLALAKGIMNM
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHH
HHGKIEVESTVGEGTKFILSLPLGNRHFSDEEMAVTEGRESLIIPEASVSSYGQLMAEEI
CCCEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHCCCCEEEECCCCHHHHHHHHHHHH
KEPESQKNMDEEDKPTILLVDDNTELLSMLEDIFLPMYNVYTACNGREGLEMAQQIQPDL
CCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
IVSDVIMPEMSGKDLCYKIKTNVELSHISVVLLTAQTSVEYVVEGLMFGADDYITKPFNI
EEHHHHCCCCCCCCEEEEEECCEEEEEEEEEEEEECCHHHHHHHHHHCCCCHHCCCCCCE
KVLVARCNNLIKNKKRLIAHYAGKVITESPVAEAINEKDKELLTKCVNIVRENFENPDFD
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCH
VTALASELCMGRSKLYMQFKQMTGLTPNEFILKVKLDEAMSLLTEHPELNITEISVRLGF
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCCCEEEEEEEECC
SSPRYFSKSFKAFFGIAPQGVRSRKE
CCCHHHHHHHHHHHCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]