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The map label for this gene is hutH [H]

Identifier: 29348099

GI number: 29348099

Start: 3352437

End: 3353936

Strand: Reverse

Name: hutH [H]

Synonym: BT_2690

Alternate gene names: 29348099

Gene position: 3353936-3352437 (Counterclockwise)

Preceding gene: 29348100

Following gene: 29348098

Centisome position: 53.57

GC content: 49.8

Gene sequence:

>1500_bases
ATGAGCAAGAATGTGTATCAAATAGGTTCCGGAGAACTGACCTTCGAAATCATCGAACGGATCATCAACGAGAATCTGAA
GCTGGAACTGGCTCCCGAAGCCAAGCTCCGCATTCAGAAATGCCGTGATTATCTCGACCATAAAATAGCTTCTTCCGAAG
AACCTCTTTATGGCATCACCACCGGCTTCGGCTCGTTATGCACTAAAAATATATCTCCCGGCGAATTGGGAACCTTGCAG
GAAAACCTGATAAAGAGCCATGCCTGCAGTGTAGGCGAAGAAATCCGTCCTGTCATCATCAAACTGATGATGTTGCTCAA
AGCCCACGCCCTCTCGTTGGGACATAGCGGCGTGCAACTAATCACTGTGCAGCGTATCCTCGACTTTTTCAATAACGACG
TACTGCCCATCGTCTATGATCGCGGTTCTTTGGGAGCTTCCGGCGATCTCGCCCCATTAGCCAATCTGTTCCTTCCTTTG
ATCGGTGTGGGCGACGTCAACTATAAAGGAAAGAAATGCGAAGCCATCAGCGTGCTCGACGAATTTGGCTGGGAACCCGT
CCGGCTCATGAGCAAGGAAGGGCTTGCACTGCTCAACGGTACCCAGTTCATGAGTGCCAACGGTGTATTTGCCATTCTCA
AAGCCTTCCGCCTCTCCAAGAAAGCCGACCTGATAGCCGCCCTTTCTCTCGAAGCCTTCGACGGACGCATCGACCCGTTT
ATGGATTGCATCCAGCAGATACGCCCTCATCCCGGACAGATCGAGACGGGAGAGGCTTTCCGTAAACTGCTGGCAGGCAG
CGAACTGATCGAACGTCCCAAGGCGCACGTACAGGATCCTTACTCTTTCCGTTGCATTCCGCAAGTGCATGGTGCTACGA
AAGACGCTATCCGCTATGTTTCCTCCGTACTGCTGACCGAAATCAATTCCGTCACGGACAATCCAACGATCTTCCCTGAC
GAAGACAGAATCATTTCCGGTGGAAATTTCCACGGTCAGCCGTTGGCTATCTCCTATGACTTTCTAGCCATTGCCTTGGC
AGAACTGGGAAACATTTCCGAACGCCGTGTCTCTCAATTGATTATGGGACTTCGCGAACTTCCGGAGTTTTTGGTAGCCA
ATCCGGGACTGAATTCCGGTTTTATGATTCCCCAATATGCTGCTGCGTCTATGGTCAGCCAGAACAAAATGTACTGTTAT
GCCGCATCGAGCGATTCCATCGTTTCGTCCAACGGGCAGGAAGACCACGTAAGTATGGGGGCCAATGCCGCAACCAAACT
TTATAAAGTGATGGACAACCTTGAACATATCCTTGCCATCGAACTGATGAATGCTGCGCAGGGCATCGATTTCCGCCGTC
CGCTGAAAACGTCTCCGCTGCTGGAGAGTTTCCTGCATGCCTACCGGAAAGAAGTGCCTTTTGTGAAAGATGACATCGTG
ATGTATAAAGAAATACATAAAACAGTCGCTTTTTTAAAAAGGACTAAGTTAGAGTACTAA

Upstream 100 bases:

>100_bases
AATTTGTCCAAGAATTGCAAGCCGAAGCGGACCGGATAGAGCAAACCGCTTGCCGGAAAGAGAAAGAATTACTGGATGCC
GTCAACCAAGACTTACGCGT

Downstream 100 bases:

>100_bases
ACCTCCTTTTTCGCTTTTCGTTAATAATGGTGACTGTTATTGCCGGATAAACGATCGATTCTTATCGGTATTTATCCGGC
ATTTGCCGATTATTCTCCCT

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MSKNVYQIGSGELTFEIIERIINENLKLELAPEAKLRIQKCRDYLDHKIASSEEPLYGITTGFGSLCTKNISPGELGTLQ
ENLIKSHACSVGEEIRPVIIKLMMLLKAHALSLGHSGVQLITVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPL
IGVGDVNYKGKKCEAISVLDEFGWEPVRLMSKEGLALLNGTQFMSANGVFAILKAFRLSKKADLIAALSLEAFDGRIDPF
MDCIQQIRPHPGQIETGEAFRKLLAGSELIERPKAHVQDPYSFRCIPQVHGATKDAIRYVSSVLLTEINSVTDNPTIFPD
EDRIISGGNFHGQPLAISYDFLAIALAELGNISERRVSQLIMGLRELPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCY
AASSDSIVSSNGQEDHVSMGANAATKLYKVMDNLEHILAIELMNAAQGIDFRRPLKTSPLLESFLHAYRKEVPFVKDDIV
MYKEIHKTVAFLKRTKLEY

Sequences:

>Translated_499_residues
MSKNVYQIGSGELTFEIIERIINENLKLELAPEAKLRIQKCRDYLDHKIASSEEPLYGITTGFGSLCTKNISPGELGTLQ
ENLIKSHACSVGEEIRPVIIKLMMLLKAHALSLGHSGVQLITVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPL
IGVGDVNYKGKKCEAISVLDEFGWEPVRLMSKEGLALLNGTQFMSANGVFAILKAFRLSKKADLIAALSLEAFDGRIDPF
MDCIQQIRPHPGQIETGEAFRKLLAGSELIERPKAHVQDPYSFRCIPQVHGATKDAIRYVSSVLLTEINSVTDNPTIFPD
EDRIISGGNFHGQPLAISYDFLAIALAELGNISERRVSQLIMGLRELPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCY
AASSDSIVSSNGQEDHVSMGANAATKLYKVMDNLEHILAIELMNAAQGIDFRRPLKTSPLLESFLHAYRKEVPFVKDDIV
MYKEIHKTVAFLKRTKLEY
>Mature_498_residues
SKNVYQIGSGELTFEIIERIINENLKLELAPEAKLRIQKCRDYLDHKIASSEEPLYGITTGFGSLCTKNISPGELGTLQE
NLIKSHACSVGEEIRPVIIKLMMLLKAHALSLGHSGVQLITVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPLI
GVGDVNYKGKKCEAISVLDEFGWEPVRLMSKEGLALLNGTQFMSANGVFAILKAFRLSKKADLIAALSLEAFDGRIDPFM
DCIQQIRPHPGQIETGEAFRKLLAGSELIERPKAHVQDPYSFRCIPQVHGATKDAIRYVSSVLLTEINSVTDNPTIFPDE
DRIISGGNFHGQPLAISYDFLAIALAELGNISERRVSQLIMGLRELPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCYA
ASSDSIVSSNGQEDHVSMGANAATKLYKVMDNLEHILAIELMNAAQGIDFRRPLKTSPLLESFLHAYRKEVPFVKDDIVM
YKEIHKTVAFLKRTKLEY

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=480, Percent_Identity=43.5416666666667, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17567831, Length=481, Percent_Identity=41.5800415800416, Blast_Score=343, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 55179; Mature: 55047

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNVYQIGSGELTFEIIERIINENLKLELAPEAKLRIQKCRDYLDHKIASSEEPLYGIT
CCCCEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEC
TGFGSLCTKNISPGELGTLQENLIKSHACSVGEEIRPVIIKLMMLLKAHALSLGHSGVQL
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ITVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPLIGVGDVNYKGKKCEAISVLD
HHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
EFGWEPVRLMSKEGLALLNGTQFMSANGVFAILKAFRLSKKADLIAALSLEAFDGRIDPF
HHCCCHHHHHHHCCCEEECCCCEECCCCHHHHHHHHHHCHHHHHHHHEEHHHHCCCCCHH
MDCIQQIRPHPGQIETGEAFRKLLAGSELIERPKAHVQDPYSFRCIPQVHGATKDAIRYV
HHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHCCHHHCCCCCCEEEEHHHCCCCHHHHHHH
SSVLLTEINSVTDNPTIFPDEDRIISGGNFHGQPLAISYDFLAIALAELGNISERRVSQL
HHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHH
IMGLRELPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCYAASSDSIVSSNGQEDHVSMG
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEECCCCCHHHHHCC
ANAATKLYKVMDNLEHILAIELMNAAQGIDFRRPLKTSPLLESFLHAYRKEVPFVKDDIV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
MYKEIHKTVAFLKRTKLEY
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKNVYQIGSGELTFEIIERIINENLKLELAPEAKLRIQKCRDYLDHKIASSEEPLYGIT
CCCEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEC
TGFGSLCTKNISPGELGTLQENLIKSHACSVGEEIRPVIIKLMMLLKAHALSLGHSGVQL
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ITVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPLIGVGDVNYKGKKCEAISVLD
HHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
EFGWEPVRLMSKEGLALLNGTQFMSANGVFAILKAFRLSKKADLIAALSLEAFDGRIDPF
HHCCCHHHHHHHCCCEEECCCCEECCCCHHHHHHHHHHCHHHHHHHHEEHHHHCCCCCHH
MDCIQQIRPHPGQIETGEAFRKLLAGSELIERPKAHVQDPYSFRCIPQVHGATKDAIRYV
HHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHCCHHHCCCCCCEEEEHHHCCCCHHHHHHH
SSVLLTEINSVTDNPTIFPDEDRIISGGNFHGQPLAISYDFLAIALAELGNISERRVSQL
HHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHH
IMGLRELPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCYAASSDSIVSSNGQEDHVSMG
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEECCCCCHHHHHCC
ANAATKLYKVMDNLEHILAIELMNAAQGIDFRRPLKTSPLLESFLHAYRKEVPFVKDDIV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
MYKEIHKTVAFLKRTKLEY
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]