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The map label for this gene is fchA [H]

Identifier: 29348100

GI number: 29348100

Start: 3353933

End: 3354562

Strand: Reverse

Name: fchA [H]

Synonym: BT_2691

Alternate gene names: 29348100

Gene position: 3354562-3353933 (Counterclockwise)

Preceding gene: 29348101

Following gene: 29348099

Centisome position: 53.58

GC content: 50.16

Gene sequence:

>630_bases
ATGTTAGCAGATTTAACCGTAAAAGATTTCTTAGATAAGGTAGCCGGCAATGATCCGGTACCCGGCGGTGGCAGTATTGC
CGCTTTAGGTGGAGCGCTGGCTTCCGCTTTGGCCACGATGGTGACAGGACTCACCATCGGCAAGAAAGGATATGAAGCCA
GCGAAGAAGTAATGCAGCACGCACAGACGCTTACCACCCGATTCCAAAAAGAATTCATCGCCTTGATTGATAAAGACTCC
GAAGCCTATGATGAAGTTTTTGCCTGTTTTAAACTTCCCAAAGCTACCGATGAAGAAAAAGCTGTCCGTAGCGCTGCCAT
TCAGGAAGCCACCAGGCATGCCGCCCTCATTCCGATGGAAGTTGCCCGAAAAGCACTTGAAGTGATGCCCGTCATAGCAG
ACATCGCCCGTCTGGGAAACCGGAACGCTATTACAGACGCCTGTGTAGCCATGATGGCAGCACGATCCGCCGTATTGGGG
GCATTGCTGAATGTCCGCATTAATCTGGGGGTACTTAAAGACAAAGAATTTGTCCAAGAATTGCAAGCCGAAGCGGACCG
GATAGAGCAAACCGCTTGCCGGAAAGAGAAAGAATTACTGGATGCCGTCAACCAAGACTTACGCGTATGA

Upstream 100 bases:

>100_bases
TCACATTCTGCCATACTACGTAGGCATGAACTGTGTCATCATGACTATTAAAGGCGGTATGCTATACCCCGTCAATTGAT
AACTAAAAGCATAAAATACC

Downstream 100 bases:

>100_bases
GCAAGAATGTGTATCAAATAGGTTCCGGAGAACTGACCTTCGAAATCATCGAACGGATCATCAACGAGAATCTGAAGCTG
GAACTGGCTCCCGAAGCCAA

Product: methenyltetrahydrofolate cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MLADLTVKDFLDKVAGNDPVPGGGSIAALGGALASALATMVTGLTIGKKGYEASEEVMQHAQTLTTRFQKEFIALIDKDS
EAYDEVFACFKLPKATDEEKAVRSAAIQEATRHAALIPMEVARKALEVMPVIADIARLGNRNAITDACVAMMAARSAVLG
ALLNVRINLGVLKDKEFVQELQAEADRIEQTACRKEKELLDAVNQDLRV

Sequences:

>Translated_209_residues
MLADLTVKDFLDKVAGNDPVPGGGSIAALGGALASALATMVTGLTIGKKGYEASEEVMQHAQTLTTRFQKEFIALIDKDS
EAYDEVFACFKLPKATDEEKAVRSAAIQEATRHAALIPMEVARKALEVMPVIADIARLGNRNAITDACVAMMAARSAVLG
ALLNVRINLGVLKDKEFVQELQAEADRIEQTACRKEKELLDAVNQDLRV
>Mature_209_residues
MLADLTVKDFLDKVAGNDPVPGGGSIAALGGALASALATMVTGLTIGKKGYEASEEVMQHAQTLTTRFQKEFIALIDKDS
EAYDEVFACFKLPKATDEEKAVRSAAIQEATRHAALIPMEVARKALEVMPVIADIARLGNRNAITDACVAMMAARSAVLG
ALLNVRINLGVLKDKEFVQELQAEADRIEQTACRKEKELLDAVNQDLRV

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=165, Percent_Identity=29.6969696969697, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI11140815, Length=165, Percent_Identity=29.6969696969697, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 22470; Mature: 22470

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLADLTVKDFLDKVAGNDPVPGGGSIAALGGALASALATMVTGLTIGKKGYEASEEVMQH
CCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AQTLTTRFQKEFIALIDKDSEAYDEVFACFKLPKATDEEKAVRSAAIQEATRHAALIPME
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
VARKALEVMPVIADIARLGNRNAITDACVAMMAARSAVLGALLNVRINLGVLKDKEFVQE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LQAEADRIEQTACRKEKELLDAVNQDLRV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLADLTVKDFLDKVAGNDPVPGGGSIAALGGALASALATMVTGLTIGKKGYEASEEVMQH
CCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AQTLTTRFQKEFIALIDKDSEAYDEVFACFKLPKATDEEKAVRSAAIQEATRHAALIPME
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
VARKALEVMPVIADIARLGNRNAITDACVAMMAARSAVLGALLNVRINLGVLKDKEFVQE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LQAEADRIEQTACRKEKELLDAVNQDLRV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]