Click here to switch to the map view.

The map label for this gene is evgS [H]

Identifier: 29348029

GI number: 29348029

Start: 3259854

End: 3262226

Strand: Reverse

Name: evgS [H]

Synonym: BT_2619

Alternate gene names: 29348029

Gene position: 3262226-3259854 (Counterclockwise)

Preceding gene: 29348030

Following gene: 29348028

Centisome position: 52.11

GC content: 48.38

Gene sequence:

>2373_bases
ATGTGGCTGAGATTTAAAATATTTATAGGATATATTACTCTGATTGCCCTGCTCTCTTTTACTATTTATTTCTTCCGTAA
GGAACAGATGAAGCGCAACTGTTTGCAACAGCATGAACAGGAACTGCTTCATTTTTGGCATTTGACCGGAGAAGCCTACG
CCGGCCTGTTGGATCTGGGCACTTATGGAGAGACGGTCAGTGTGTGGGACGAGGACGACCGGAGTACTTATCAGAAAAAG
AGAAACGAGGTATGCGGCACATTACAGTTCTTGAAGCAATATGTCCATGCATCCGGACAACGGGTACGTATAGATTCGCT
GTGCCTGCTTCTGGAGAGAAAGGAACAGTTGCTTGACACGGTAATACATACGTTCAGCCGTTTTCGTGAAGCCGGTGAAA
TCATAAACCGGAAAATCCCGATGATTGCATCCCGTGTCCACGATGAGAAAGCGCCTATTGAAGTCAAAGAGGAAGTTCCG
AAGAAAAGTTTCTGGTCCTTCCTTAAACGCAAGAAGAGAAAATCCGTTTATTCGGAACAGAAGGAAAAACGGGAACGGCT
GCAACCTGCGGAAAAAGACCGGAAGGTCTCAACTGCAAGTATACTTCATTCTTTAAACAGGGAACTGACCGGCCGGCAGG
AGACTGAGCGTGAACGTCTGCCGGTACAAATGGAGCGTCTGTTCAATAACAATATGGCATTAAACTGCAGATTGTACGGT
ATCATCAGAGATTTTGAATTTGAGACTGACCGACGCCTTGAGGAACGTTACATGCAGTTCCTCAAGGCACGGGAACGGTC
CTTTTATACGGTTTCTACCTTTGCTGTTTTTATTTCATTGCTGACTATTTTACTTTATATCATTATACATCGGGAGTTGA
ACCGGCGAAACCGATACCGGCGTCAGCTGGAAGCTTCCAACTTGGAAAACACGGAACTCCTCCAATCCAGGAAGCGTATG
ATGCTGACTATCGCCCATGACCTGCGCTCTCCCCTTGCCATTATCAGAGCAACGGCGGAGCTGCTGCCCGGCGAACAGGA
AAGGGCTATGCAGGAGGAATACGCCGGAAATATCCGACATGCGTCAGACTATATGCTTTCGCTGGTGGACACATTGATGA
ATTTCTATCTGCTTGATACAGGACAGGCACGGGAGAATATTTCCGTCTTTTGTCTGGAAACCCTGTTCAGGGAGATTACC
AACAATTACATGCCGCTCGTTCAAAAGAAAGGATTGCAACTGTTGACCCGGTATTCCGGCATGAACGCTGCTGTCAGTTG
TGACAAGGGACATTTACAGCAGATTGTGAATAATCTGCTTTCCAACGCTCTGAAATTTACCGGGAAAGGATATGTCCGGC
TGGAAGCGACATTCAACGTCGGCGAACTGTGTATCAAAGTGCAGGATACAGGAGCGGGAATGAATGATGAGGAGCAGAAA
CGGATATTCGATGCGTTCGAAAGGCTTGATAATGCCCGCGGCGTTTCCGGTTTCGGACTTGGCCTTGCCATTGTTTCCCG
GCTTGTTTCACAGCTGGGCGGTTCCATCGGGGTGGAGAGTCACCCGGGGAAAGGAAGTTGTTTTAGGGTATCTCTTCCCC
TTTTCCCTGCCGACAGTAGTTCCTTGAAGGAGGAGTTACAATCTCCGTCTGACTATCAAATAGAAGGACTGCGTATTCTC
CTTCTTGACGATGACCCGAGACAGCTTTCCGTAACACGTGAGATGTTCAGGCGAAACCGGGTTGAATGTGACTGTTATAC
CGATTTCCGGCAGGTGGTTGCAAAATTGCGGGATGAGGATTATGACGCGTTGCTGACGGATATCCGCATGCCTGACATGG
ACGGGTTCGGGCTGCTGGAGTTGTTGCGTTCATCCAATATGGAAAGGGCCGGAACAATTCCGGTCATAGCCATGACTGCC
GATATTGATCCGGAAGAGGAGTACCTTTCCCGGGGATTTGCCGGATGTATCCGTAAACCCTTCCGGATGAATGAGCTGCT
GGAAACCGTTTCCCGAATTGTCAGAGGGAATAGGCGGACGGCATGGCAACCGGATTTTTCCCTGATTCTGACCGGGGAGG
ACAATAAGGGGGAGATGCTCGGTATCTTCATCCGGGAAAGCCGCAAGGACCTTGACAGGTTGCACGGGGCGTTGGAAAGG
GATGATCGTCAGACAGTCCGTGAGATTCTGCACAAGAACCTTCCCCTGTGGACAAGTGTCCGCCTTGATTATCCGATAGA
GGAACTGCAGGCTATTGTACTGTCCGATCCGGAACTCTGGACGGAAGAACAGATAAGGTGTATCTATAAAGTAGGAGAAG
CAGCGTGGAAACTAATTGTCTGTGCTGAAAATATGAAGAAGAATATAAAATAA

Upstream 100 bases:

>100_bases
ATAGGCGGGTAATGGTCTGTGTATGTTCACTGCTATTATCTGCCTGTTATTTTCCTGAGTCGTTAGGACAAGAAAAGGAT
AAAGAATAACAAAACGAATC

Downstream 100 bases:

>100_bases
GCAAATGAAAAATATACTGATTATAGAGGATGATGTTGTCTTCAGCCGCAGTATCAGTAACTGGCTGAAGAAAAAGGGTA
TGGCAACCGGTCATGTGTCT

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 790; Mature: 790

Protein sequence:

>790_residues
MWLRFKIFIGYITLIALLSFTIYFFRKEQMKRNCLQQHEQELLHFWHLTGEAYAGLLDLGTYGETVSVWDEDDRSTYQKK
RNEVCGTLQFLKQYVHASGQRVRIDSLCLLLERKEQLLDTVIHTFSRFREAGEIINRKIPMIASRVHDEKAPIEVKEEVP
KKSFWSFLKRKKRKSVYSEQKEKRERLQPAEKDRKVSTASILHSLNRELTGRQETERERLPVQMERLFNNNMALNCRLYG
IIRDFEFETDRRLEERYMQFLKARERSFYTVSTFAVFISLLTILLYIIIHRELNRRNRYRRQLEASNLENTELLQSRKRM
MLTIAHDLRSPLAIIRATAELLPGEQERAMQEEYAGNIRHASDYMLSLVDTLMNFYLLDTGQARENISVFCLETLFREIT
NNYMPLVQKKGLQLLTRYSGMNAAVSCDKGHLQQIVNNLLSNALKFTGKGYVRLEATFNVGELCIKVQDTGAGMNDEEQK
RIFDAFERLDNARGVSGFGLGLAIVSRLVSQLGGSIGVESHPGKGSCFRVSLPLFPADSSSLKEELQSPSDYQIEGLRIL
LLDDDPRQLSVTREMFRRNRVECDCYTDFRQVVAKLRDEDYDALLTDIRMPDMDGFGLLELLRSSNMERAGTIPVIAMTA
DIDPEEEYLSRGFAGCIRKPFRMNELLETVSRIVRGNRRTAWQPDFSLILTGEDNKGEMLGIFIRESRKDLDRLHGALER
DDRQTVREILHKNLPLWTSVRLDYPIEELQAIVLSDPELWTEEQIRCIYKVGEAAWKLIVCAENMKKNIK

Sequences:

>Translated_790_residues
MWLRFKIFIGYITLIALLSFTIYFFRKEQMKRNCLQQHEQELLHFWHLTGEAYAGLLDLGTYGETVSVWDEDDRSTYQKK
RNEVCGTLQFLKQYVHASGQRVRIDSLCLLLERKEQLLDTVIHTFSRFREAGEIINRKIPMIASRVHDEKAPIEVKEEVP
KKSFWSFLKRKKRKSVYSEQKEKRERLQPAEKDRKVSTASILHSLNRELTGRQETERERLPVQMERLFNNNMALNCRLYG
IIRDFEFETDRRLEERYMQFLKARERSFYTVSTFAVFISLLTILLYIIIHRELNRRNRYRRQLEASNLENTELLQSRKRM
MLTIAHDLRSPLAIIRATAELLPGEQERAMQEEYAGNIRHASDYMLSLVDTLMNFYLLDTGQARENISVFCLETLFREIT
NNYMPLVQKKGLQLLTRYSGMNAAVSCDKGHLQQIVNNLLSNALKFTGKGYVRLEATFNVGELCIKVQDTGAGMNDEEQK
RIFDAFERLDNARGVSGFGLGLAIVSRLVSQLGGSIGVESHPGKGSCFRVSLPLFPADSSSLKEELQSPSDYQIEGLRIL
LLDDDPRQLSVTREMFRRNRVECDCYTDFRQVVAKLRDEDYDALLTDIRMPDMDGFGLLELLRSSNMERAGTIPVIAMTA
DIDPEEEYLSRGFAGCIRKPFRMNELLETVSRIVRGNRRTAWQPDFSLILTGEDNKGEMLGIFIRESRKDLDRLHGALER
DDRQTVREILHKNLPLWTSVRLDYPIEELQAIVLSDPELWTEEQIRCIYKVGEAAWKLIVCAENMKKNIK
>Mature_790_residues
MWLRFKIFIGYITLIALLSFTIYFFRKEQMKRNCLQQHEQELLHFWHLTGEAYAGLLDLGTYGETVSVWDEDDRSTYQKK
RNEVCGTLQFLKQYVHASGQRVRIDSLCLLLERKEQLLDTVIHTFSRFREAGEIINRKIPMIASRVHDEKAPIEVKEEVP
KKSFWSFLKRKKRKSVYSEQKEKRERLQPAEKDRKVSTASILHSLNRELTGRQETERERLPVQMERLFNNNMALNCRLYG
IIRDFEFETDRRLEERYMQFLKARERSFYTVSTFAVFISLLTILLYIIIHRELNRRNRYRRQLEASNLENTELLQSRKRM
MLTIAHDLRSPLAIIRATAELLPGEQERAMQEEYAGNIRHASDYMLSLVDTLMNFYLLDTGQARENISVFCLETLFREIT
NNYMPLVQKKGLQLLTRYSGMNAAVSCDKGHLQQIVNNLLSNALKFTGKGYVRLEATFNVGELCIKVQDTGAGMNDEEQK
RIFDAFERLDNARGVSGFGLGLAIVSRLVSQLGGSIGVESHPGKGSCFRVSLPLFPADSSSLKEELQSPSDYQIEGLRIL
LLDDDPRQLSVTREMFRRNRVECDCYTDFRQVVAKLRDEDYDALLTDIRMPDMDGFGLLELLRSSNMERAGTIPVIAMTA
DIDPEEEYLSRGFAGCIRKPFRMNELLETVSRIVRGNRRTAWQPDFSLILTGEDNKGEMLGIFIRESRKDLDRLHGALER
DDRQTVREILHKNLPLWTSVRLDYPIEELQAIVLSDPELWTEEQIRCIYKVGEAAWKLIVCAENMKKNIK

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=437, Percent_Identity=26.7734553775744, Blast_Score=162, Evalue=8e-41,
Organism=Escherichia coli, GI87081816, Length=431, Percent_Identity=26.4501160092807, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI48994928, Length=391, Percent_Identity=26.0869565217391, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1789149, Length=451, Percent_Identity=24.390243902439, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788549, Length=263, Percent_Identity=25.4752851711027, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790861, Length=195, Percent_Identity=31.2820512820513, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=26.7543859649123, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=287, Percent_Identity=26.4808362369338, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=26.8722466960352, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=270, Percent_Identity=27.4074074074074, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=24.8908296943231, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786783, Length=215, Percent_Identity=26.5116279069767, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=24.7787610619469, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91956; Mature: 91956

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLRFKIFIGYITLIALLSFTIYFFRKEQMKRNCLQQHEQELLHFWHLTGEAYAGLLDLG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TYGETVSVWDEDDRSTYQKKRNEVCGTLQFLKQYVHASGQRVRIDSLCLLLERKEQLLDT
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHH
VIHTFSRFREAGEIINRKIPMIASRVHDEKAPIEVKEEVPKKSFWSFLKRKKRKSVYSEQ
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
KEKRERLQPAEKDRKVSTASILHSLNRELTGRQETERERLPVQMERLFNNNMALNCRLYG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCEEEEEEEE
IIRDFEFETDRRLEERYMQFLKARERSFYTVSTFAVFISLLTILLYIIIHRELNRRNRYR
EEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLEASNLENTELLQSRKRMMLTIAHDLRSPLAIIRATAELLPGEQERAMQEEYAGNIRH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
ASDYMLSLVDTLMNFYLLDTGQARENISVFCLETLFREITNNYMPLVQKKGLQLLTRYSG
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
MNAAVSCDKGHLQQIVNNLLSNALKFTGKGYVRLEATFNVGELCIKVQDTGAGMNDEEQK
CCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHH
RIFDAFERLDNARGVSGFGLGLAIVSRLVSQLGGSIGVESHPGKGSCFRVSLPLFPADSS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCH
SLKEELQSPSDYQIEGLRILLLDDDPRQLSVTREMFRRNRVECDCYTDFRQVVAKLRDED
HHHHHHCCCCCCEECCEEEEEECCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCC
YDALLTDIRMPDMDGFGLLELLRSSNMERAGTIPVIAMTADIDPEEEYLSRGFAGCIRKP
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
FRMNELLETVSRIVRGNRRTAWQPDFSLILTGEDNKGEMLGIFIRESRKDLDRLHGALER
CHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHCC
DDRQTVREILHKNLPLWTSVRLDYPIEELQAIVLSDPELWTEEQIRCIYKVGEAAWKLIV
CHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHE
CAENMKKNIK
EHHHHHCCCC
>Mature Secondary Structure
MWLRFKIFIGYITLIALLSFTIYFFRKEQMKRNCLQQHEQELLHFWHLTGEAYAGLLDLG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TYGETVSVWDEDDRSTYQKKRNEVCGTLQFLKQYVHASGQRVRIDSLCLLLERKEQLLDT
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHH
VIHTFSRFREAGEIINRKIPMIASRVHDEKAPIEVKEEVPKKSFWSFLKRKKRKSVYSEQ
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
KEKRERLQPAEKDRKVSTASILHSLNRELTGRQETERERLPVQMERLFNNNMALNCRLYG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCEEEEEEEE
IIRDFEFETDRRLEERYMQFLKARERSFYTVSTFAVFISLLTILLYIIIHRELNRRNRYR
EEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLEASNLENTELLQSRKRMMLTIAHDLRSPLAIIRATAELLPGEQERAMQEEYAGNIRH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
ASDYMLSLVDTLMNFYLLDTGQARENISVFCLETLFREITNNYMPLVQKKGLQLLTRYSG
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
MNAAVSCDKGHLQQIVNNLLSNALKFTGKGYVRLEATFNVGELCIKVQDTGAGMNDEEQK
CCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHH
RIFDAFERLDNARGVSGFGLGLAIVSRLVSQLGGSIGVESHPGKGSCFRVSLPLFPADSS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCH
SLKEELQSPSDYQIEGLRILLLDDDPRQLSVTREMFRRNRVECDCYTDFRQVVAKLRDED
HHHHHHCCCCCCEECCEEEEEECCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCC
YDALLTDIRMPDMDGFGLLELLRSSNMERAGTIPVIAMTADIDPEEEYLSRGFAGCIRKP
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
FRMNELLETVSRIVRGNRRTAWQPDFSLILTGEDNKGEMLGIFIRESRKDLDRLHGALER
CHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHCC
DDRQTVREILHKNLPLWTSVRLDYPIEELQAIVLSDPELWTEEQIRCIYKVGEAAWKLIV
CHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHE
CAENMKKNIK
EHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]