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The map label for this gene is zraR [H]

Identifier: 29348028

GI number: 29348028

Start: 3258569

End: 3259849

Strand: Reverse

Name: zraR [H]

Synonym: BT_2618

Alternate gene names: 29348028

Gene position: 3259849-3258569 (Counterclockwise)

Preceding gene: 29348029

Following gene: 29348027

Centisome position: 52.07

GC content: 53.79

Gene sequence:

>1281_bases
ATGAAAAATATACTGATTATAGAGGATGATGTTGTCTTCAGCCGCAGTATCAGTAACTGGCTGAAGAAAAAGGGTATGGC
AACCGGTCATGTGTCTACACTCTCGGCAGCCCGTAAGGAACTTCAGGTTAAGAAGTTCGACCTTGTCCTGGCAGACCTGC
GTCTGCCGGACGGCAGCAGTATGGAGCTGCTGAAGTGGATGAAAGGAAAATATTATTCCATCCCGTTCCTTATTATGACC
AGTTACGGCCAGGTGGAGAATGCGGTGGAAGCCATGCAGCTTGGGGCCTCCAATTACCTTTGCAAGCCGGTACAGCCGGA
CCGGCTTTGGGAAGTTATAGAAAAAGAGTTCAGCCGTCCGCAGCATGGCAGCACGGAATTCTACCGTGGTGAAAGTGAAA
AGGCCCGTGAAATGTACCGGCTGATAGGCCCTGTGGCCCGTTCTGACATGTCCGTCCTGCTTCGTGGAGCATCGGGTACG
GGTAAGGAACATATTGCCGCTGAGATTCATGAGTGGAGCCTGCGCAGGCACAAGCCTTTTGTAGCCGTGGACTGCGGTGC
CGTTTCCGACGACCTTGTCAGATCCGAATTCTTCGGGTACTGCAAAGGGGCGTTCACCGGTGCGGACAGTGACAAGGCGG
GACTTTTCCAGGCTGCTGAAGGTGGTACGTTGTTCCTTGATGAAATCGGTAACCTTGCTCCCGTAAATCAGATGAAACTG
CTTCGCGCCCTGCAAGAAAAGCGTTACCTGCCGGTCGGGACAGTCAGGGAACGTCCCTTTGACATCCGCCTTATCGCCGC
CACCAATGCAGATTTGGAGAAGGCCATTGCGGAAGGGAGTTTCCGTGAGGACTTGTACCACCGTCTGAACGAGTTCACTA
TCCGGGTTCCCCTGCTCTCCGAATGCGGGGAGGATATCCTTCCGTTGGCTGAATTCTTTCTGAAGCAGTTTTCCGCAAGA
TACGGGAAACCGGTTCAGGGCTTCGACCGGGAAGCGGCTGCCGTGTTACGGCAATACGGCTGGCCGGGGAATATCCGTGA
ACTGAAGAATACTGTCCGGCGTGCCGTCGTGTTTGCCGGGGAGGGGCGGATATCCGCACAGGAACTGAATCTGGATCAGG
GCATGAAATTGGGAAACATGATTGTCTGTCCGGAAAAGGAGGAGCAGCAGATACTTCGGATACTTGGGCAGACCGGTAAC
AACCGCACCCTTACCGCCCGTGTACTCGGCATCAGCCGGACTGCCCTGTATTACAAGTTGAGGAAATACGGTATTGTGTG
A

Upstream 100 bases:

>100_bases
TGGACGGAAGAACAGATAAGGTGTATCTATAAAGTAGGAGAAGCAGCGTGGAAACTAATTGTCTGTGCTGAAAATATGAA
GAAGAATATAAAATAAGCAA

Downstream 100 bases:

>100_bases
ATAAGGGAATATAGGACAGCCCCCGGAAAACGGGGGCTATTTCAGTATGCTCGGCATGGTTATTAGCTACCGGGTGCAAG
TCCCCAATGAGCCCTAATAG

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKNILIIEDDVVFSRSISNWLKKKGMATGHVSTLSAARKELQVKKFDLVLADLRLPDGSSMELLKWMKGKYYSIPFLIMT
SYGQVENAVEAMQLGASNYLCKPVQPDRLWEVIEKEFSRPQHGSTEFYRGESEKAREMYRLIGPVARSDMSVLLRGASGT
GKEHIAAEIHEWSLRRHKPFVAVDCGAVSDDLVRSEFFGYCKGAFTGADSDKAGLFQAAEGGTLFLDEIGNLAPVNQMKL
LRALQEKRYLPVGTVRERPFDIRLIAATNADLEKAIAEGSFREDLYHRLNEFTIRVPLLSECGEDILPLAEFFLKQFSAR
YGKPVQGFDREAAAVLRQYGWPGNIRELKNTVRRAVVFAGEGRISAQELNLDQGMKLGNMIVCPEKEEQQILRILGQTGN
NRTLTARVLGISRTALYYKLRKYGIV

Sequences:

>Translated_426_residues
MKNILIIEDDVVFSRSISNWLKKKGMATGHVSTLSAARKELQVKKFDLVLADLRLPDGSSMELLKWMKGKYYSIPFLIMT
SYGQVENAVEAMQLGASNYLCKPVQPDRLWEVIEKEFSRPQHGSTEFYRGESEKAREMYRLIGPVARSDMSVLLRGASGT
GKEHIAAEIHEWSLRRHKPFVAVDCGAVSDDLVRSEFFGYCKGAFTGADSDKAGLFQAAEGGTLFLDEIGNLAPVNQMKL
LRALQEKRYLPVGTVRERPFDIRLIAATNADLEKAIAEGSFREDLYHRLNEFTIRVPLLSECGEDILPLAEFFLKQFSAR
YGKPVQGFDREAAAVLRQYGWPGNIRELKNTVRRAVVFAGEGRISAQELNLDQGMKLGNMIVCPEKEEQQILRILGQTGN
NRTLTARVLGISRTALYYKLRKYGIV
>Mature_426_residues
MKNILIIEDDVVFSRSISNWLKKKGMATGHVSTLSAARKELQVKKFDLVLADLRLPDGSSMELLKWMKGKYYSIPFLIMT
SYGQVENAVEAMQLGASNYLCKPVQPDRLWEVIEKEFSRPQHGSTEFYRGESEKAREMYRLIGPVARSDMSVLLRGASGT
GKEHIAAEIHEWSLRRHKPFVAVDCGAVSDDLVRSEFFGYCKGAFTGADSDKAGLFQAAEGGTLFLDEIGNLAPVNQMKL
LRALQEKRYLPVGTVRERPFDIRLIAATNADLEKAIAEGSFREDLYHRLNEFTIRVPLLSECGEDILPLAEFFLKQFSAR
YGKPVQGFDREAAAVLRQYGWPGNIRELKNTVRRAVVFAGEGRISAQELNLDQGMKLGNMIVCPEKEEQQILRILGQTGN
NRTLTARVLGISRTALYYKLRKYGIV

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=435, Percent_Identity=41.3793103448276, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1788905, Length=430, Percent_Identity=38.1395348837209, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=37.9690949227373, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI1790299, Length=463, Percent_Identity=33.4773218142549, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1789233, Length=331, Percent_Identity=40.785498489426, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI87082117, Length=316, Percent_Identity=37.6582278481013, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1789087, Length=314, Percent_Identity=37.8980891719745, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1786524, Length=315, Percent_Identity=38.0952380952381, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI87082152, Length=234, Percent_Identity=44.4444444444444, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1787583, Length=304, Percent_Identity=34.8684210526316, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=34.4936708860759, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789828, Length=228, Percent_Identity=41.2280701754386, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87081858, Length=336, Percent_Identity=27.6785714285714, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1790552, Length=130, Percent_Identity=30, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786911, Length=103, Percent_Identity=30.0970873786408, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 47955; Mature: 47955

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNILIIEDDVVFSRSISNWLKKKGMATGHVSTLSAARKELQVKKFDLVLADLRLPDGSS
CCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCH
MELLKWMKGKYYSIPFLIMTSYGQVENAVEAMQLGASNYLCKPVQPDRLWEVIEKEFSRP
HHHHHHHCCCCEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
QHGSTEFYRGESEKAREMYRLIGPVARSDMSVLLRGASGTGKEHIAAEIHEWSLRRHKPF
CCCCCHHCCCCCHHHHHHHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHHCCCE
VAVDCGAVSDDLVRSEFFGYCKGAFTGADSDKAGLFQAAEGGTLFLDEIGNLAPVNQMKL
EEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEHHHCCCCCCHHHHHH
LRALQEKRYLPVGTVRERPFDIRLIAATNADLEKAIAEGSFREDLYHRLNEFTIRVPLLS
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHEEEEECCHH
ECGEDILPLAEFFLKQFSARYGKPVQGFDREAAAVLRQYGWPGNIRELKNTVRRAVVFAG
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEC
EGRISAQELNLDQGMKLGNMIVCPEKEEQQILRILGQTGNNRTLTARVLGISRTALYYKL
CCCCCHHHCCHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHH
RKYGIV
HHHCCC
>Mature Secondary Structure
MKNILIIEDDVVFSRSISNWLKKKGMATGHVSTLSAARKELQVKKFDLVLADLRLPDGSS
CCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCH
MELLKWMKGKYYSIPFLIMTSYGQVENAVEAMQLGASNYLCKPVQPDRLWEVIEKEFSRP
HHHHHHHCCCCEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
QHGSTEFYRGESEKAREMYRLIGPVARSDMSVLLRGASGTGKEHIAAEIHEWSLRRHKPF
CCCCCHHCCCCCHHHHHHHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHHCCCE
VAVDCGAVSDDLVRSEFFGYCKGAFTGADSDKAGLFQAAEGGTLFLDEIGNLAPVNQMKL
EEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEHHHCCCCCCHHHHHH
LRALQEKRYLPVGTVRERPFDIRLIAATNADLEKAIAEGSFREDLYHRLNEFTIRVPLLS
HHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHEEEEECCHH
ECGEDILPLAEFFLKQFSARYGKPVQGFDREAAAVLRQYGWPGNIRELKNTVRRAVVFAG
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEC
EGRISAQELNLDQGMKLGNMIVCPEKEEQQILRILGQTGNNRTLTARVLGISRTALYYKL
CCCCCHHHCCHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHH
RKYGIV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]