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The map label for this gene is ptp [H]

Identifier: 29347846

GI number: 29347846

Start: 3050620

End: 3051984

Strand: Reverse

Name: ptp [H]

Synonym: BT_2436

Alternate gene names: 29347846

Gene position: 3051984-3050620 (Counterclockwise)

Preceding gene: 29347849

Following gene: 29347843

Centisome position: 48.75

GC content: 46.15

Gene sequence:

>1365_bases
ATGTGTAAAAAGGTTCGTGCAAATGATTATCTTTGCGAGAAAATTAACACTCAAATGCTTATGAAACACATTCGGATACC
TCTTTTCGTATGGTTCTCAATCGTGCTGCTGATCGCAGTTGCGCCCGTCTCATTGTCGGCGCAGGAATCGTTTATTCAGA
AGATCGAAAAAAATAAGTCCGTCAGCGGAATAAAGTTGCTCGACACCAGCCGCTTCCCGGAAAAGTATGTAATGTACCTG
ACTCAGCCGCTGGATCATCGACATCCCGAAAAGGGAAGTTTCCGCCAGCGGGTGATTGTGGGACACGTCGGTTATGACCG
TCCCACAGTGATTGTCACTGAAGGATATGGGGCAGGGTATGCTTTGCGCCCCACTTATCGGGAAGAACTTTCTGAATTGT
TCGATGCCAATATGATCTTTGTGGAGCATCGCTACTTTCTCGAATCCACTCCCGAACCGTGCGACTGGCAATACCTGACC
GCAGAGAATTCTGCCGAGGATTTGCATGCCGTGACAACCGCTTTCAAGACTTTATATCCTGGCAAATGGATCAGTACGGG
GATCAGCAAGGGTGGGCAGACCTCCTTATTATACCGTGTTTTCTTCCCCGACGATGTGGATGTTTCCGTGCCTTATGTTG
CTCCTCTTTGTTATGCGCGTGAAGACGGTCGGCACGAACCTTTCCTCCGCCGGGTAGGTACGGAAGCCGATAGGAAAAAA
ATAGAAGATTTCCAGTTGGAAGTATTGAAGCGAAAGGCTCGTTTGTTGCCCCGTTTTGAAAAAATGTGTACTGAAAAGAA
CTATACATTCCGCGCTCCTCTGGAAGAAATATACGATTTCTGTGTGCTGGAATACTCTTTCTCTATCTGGCAATGGGGAA
CGGATATCCGTAGTATACCGGAAACCTCGGCTTCTGACGATACACTGCTGGATCATTTGCTGGCAATCAGCGGACCTTCT
TATTTTATAGTAGACAGCCCGACTCTTTCTTTCTTCGTGCAGGCTGCCCGCGAATTGGGGTATTATGGATACGATATCGC
TCCTTTTAAACCTTACCTTTCTATAAAGACCAGCAAGGATTATCTGAGAAGACTGATGTTGCCGGAAGATATGCGGAAGA
TGAAATTCGATAAGACATTGAGCAATAAGATTGTGCGGTTCTTGAAGAAGAACGATCCGAAGATGATTTTTATCTATGGT
CAGAATGATCCCTGGACAGCTGCCGGAGTAACATGGCTGAAGAATAAAAAGAATATTCATGTTTTTGTAGAGCCGGGAGG
CAGTCATCTTGCACGCATCGGTACAATGTCCGAAGATCAGAAGCAGAAAGTGATGTCTCTTCTTAGAGGGTGGCTTGAAG
AATGA

Upstream 100 bases:

>100_bases
CAATAAAATAGGAATTAATTTCTTCATATCTTTTATAATGTTTAGGTTATATAAAAATCACGCCCTGGTACCTTGGGGCT
TTTGTTACAAACAACAAGAA

Downstream 100 bases:

>100_bases
CGAAACGAGAAACGGTGAACAACCTGTAATATATGAACAGGCGGTTCACCGTTTTATTCTTCTGCAAGCCGATATTACAT
GTATCGGGCTGCTTGATTTA

Product: putative secreted tripeptidyl aminopeptidase

Products: NA

Alternate protein names: PTP-SM; Tripeptidyl aminopeptidase; SM-TAP [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MCKKVRANDYLCEKINTQMLMKHIRIPLFVWFSIVLLIAVAPVSLSAQESFIQKIEKNKSVSGIKLLDTSRFPEKYVMYL
TQPLDHRHPEKGSFRQRVIVGHVGYDRPTVIVTEGYGAGYALRPTYREELSELFDANMIFVEHRYFLESTPEPCDWQYLT
AENSAEDLHAVTTAFKTLYPGKWISTGISKGGQTSLLYRVFFPDDVDVSVPYVAPLCYAREDGRHEPFLRRVGTEADRKK
IEDFQLEVLKRKARLLPRFEKMCTEKNYTFRAPLEEIYDFCVLEYSFSIWQWGTDIRSIPETSASDDTLLDHLLAISGPS
YFIVDSPTLSFFVQAARELGYYGYDIAPFKPYLSIKTSKDYLRRLMLPEDMRKMKFDKTLSNKIVRFLKKNDPKMIFIYG
QNDPWTAAGVTWLKNKKNIHVFVEPGGSHLARIGTMSEDQKQKVMSLLRGWLEE

Sequences:

>Translated_454_residues
MCKKVRANDYLCEKINTQMLMKHIRIPLFVWFSIVLLIAVAPVSLSAQESFIQKIEKNKSVSGIKLLDTSRFPEKYVMYL
TQPLDHRHPEKGSFRQRVIVGHVGYDRPTVIVTEGYGAGYALRPTYREELSELFDANMIFVEHRYFLESTPEPCDWQYLT
AENSAEDLHAVTTAFKTLYPGKWISTGISKGGQTSLLYRVFFPDDVDVSVPYVAPLCYAREDGRHEPFLRRVGTEADRKK
IEDFQLEVLKRKARLLPRFEKMCTEKNYTFRAPLEEIYDFCVLEYSFSIWQWGTDIRSIPETSASDDTLLDHLLAISGPS
YFIVDSPTLSFFVQAARELGYYGYDIAPFKPYLSIKTSKDYLRRLMLPEDMRKMKFDKTLSNKIVRFLKKNDPKMIFIYG
QNDPWTAAGVTWLKNKKNIHVFVEPGGSHLARIGTMSEDQKQKVMSLLRGWLEE
>Mature_454_residues
MCKKVRANDYLCEKINTQMLMKHIRIPLFVWFSIVLLIAVAPVSLSAQESFIQKIEKNKSVSGIKLLDTSRFPEKYVMYL
TQPLDHRHPEKGSFRQRVIVGHVGYDRPTVIVTEGYGAGYALRPTYREELSELFDANMIFVEHRYFLESTPEPCDWQYLT
AENSAEDLHAVTTAFKTLYPGKWISTGISKGGQTSLLYRVFFPDDVDVSVPYVAPLCYAREDGRHEPFLRRVGTEADRKK
IEDFQLEVLKRKARLLPRFEKMCTEKNYTFRAPLEEIYDFCVLEYSFSIWQWGTDIRSIPETSASDDTLLDHLLAISGPS
YFIVDSPTLSFFVQAARELGYYGYDIAPFKPYLSIKTSKDYLRRLMLPEDMRKMKFDKTLSNKIVRFLKKNDPKMIFIYG
QNDPWTAAGVTWLKNKKNIHVFVEPGGSHLARIGTMSEDQKQKVMSLLRGWLEE

Specific function: Has proline-specific tripeptidyl aminopeptidase and tetrapeptidyl aminopeptidase activity. Activity is highest against tripeptides containing an Ala-Pro motif. Involved in the final processing of transglutaminase, by removing either the tetrapeptide Phe-A

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted (PubMed:14519127). Cell surface (PubMed:15598885) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S37 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008761 [H]

Pfam domain/function: PF05576 Peptidase_S37 [H]

EC number: NA

Molecular weight: Translated: 52647; Mature: 52647

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKKVRANDYLCEKINTQMLMKHIRIPLFVWFSIVLLIAVAPVSLSAQESFIQKIEKNKS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
VSGIKLLDTSRFPEKYVMYLTQPLDHRHPEKGSFRQRVIVGHVGYDRPTVIVTEGYGAGY
CCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCE
ALRPTYREELSELFDANMIFVEHRYFLESTPEPCDWQYLTAENSAEDLHAVTTAFKTLYP
EECCHHHHHHHHHHCCCEEEEEEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
GKWISTGISKGGQTSLLYRVFFPDDVDVSVPYVAPLCYAREDGRHEPFLRRVGTEADRKK
CCHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHCCHHHHHH
IEDFQLEVLKRKARLLPRFEKMCTEKNYTFRAPLEEIYDFCVLEYSFSIWQWGTDIRSIP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHCCC
ETSASDDTLLDHLLAISGPSYFIVDSPTLSFFVQAARELGYYGYDIAPFKPYLSIKTSKD
CCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHH
YLRRLMLPEDMRKMKFDKTLSNKIVRFLKKNDPKMIFIYGQNDPWTAAGVTWLKNKKNIH
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCEEECCCCEE
VFVEPGGSHLARIGTMSEDQKQKVMSLLRGWLEE
EEECCCCCCCEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCKKVRANDYLCEKINTQMLMKHIRIPLFVWFSIVLLIAVAPVSLSAQESFIQKIEKNKS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
VSGIKLLDTSRFPEKYVMYLTQPLDHRHPEKGSFRQRVIVGHVGYDRPTVIVTEGYGAGY
CCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCE
ALRPTYREELSELFDANMIFVEHRYFLESTPEPCDWQYLTAENSAEDLHAVTTAFKTLYP
EECCHHHHHHHHHHCCCEEEEEEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
GKWISTGISKGGQTSLLYRVFFPDDVDVSVPYVAPLCYAREDGRHEPFLRRVGTEADRKK
CCHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHCCHHHHHH
IEDFQLEVLKRKARLLPRFEKMCTEKNYTFRAPLEEIYDFCVLEYSFSIWQWGTDIRSIP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHCCC
ETSASDDTLLDHLLAISGPSYFIVDSPTLSFFVQAARELGYYGYDIAPFKPYLSIKTSKD
CCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHH
YLRRLMLPEDMRKMKFDKTLSNKIVRFLKKNDPKMIFIYGQNDPWTAAGVTWLKNKKNIH
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCEEECCCCEE
VFVEPGGSHLARIGTMSEDQKQKVMSLLRGWLEE
EEECCCCCCCEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA