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The map label for this gene is kdpD [H]

Identifier: 29347831

GI number: 29347831

Start: 3023900

End: 3025033

Strand: Reverse

Name: kdpD [H]

Synonym: BT_2421

Alternate gene names: 29347831

Gene position: 3025033-3023900 (Counterclockwise)

Preceding gene: 29347832

Following gene: 29347830

Centisome position: 48.32

GC content: 46.56

Gene sequence:

>1134_bases
ATGGATATGGATAGAGAACAGAGTGTACAACATTTTTTGGATCTGATCAAGAAGTCTCATCGAGGCAAGTTTAAAATCTA
TATCGGCATGATAGCCGGTGTAGGGAAGTCTTACCGTATGCTTCAGGAGGCTCATGAACTGCTGGAGAATGGGGTGGATG
TACAAATCGGCTATATTGAAACTCACGGACGTGCCGGAACGGAGGCTCTGATGCAGGGACTGCCTGTGATCCCCCGACGT
AAAATTTTCTATAAAGGAAAAGAGTTGGAGGAAATGGATGTGGACGCCATTATCCGCCTTCATCCCGAGATTGTGATTGT
GGACGAACTGGCACACACCAATGTGGAAGGCAGTTTGAACGAGAAACGTTGGCAGGATGTGATGACTCTGTTGGATGAGG
GGATTAATGTGATTTCCGCAATCAATATCCAGCATATCGAGAGTGTGAATGAAGAAGTGCAGGAGATTACAGGGATCGAG
GTGAAAGAACGGGTGCCGGACAGTGTGCTTCAGGAAGCGGATGAAGTGGTGAATATCGACTTGACAGCGGAAGAACTGAT
CTCGCGTCTGAAAGCAGGAAAGATATACCGTCCGGAAAAGATTCAGACAGCACTGGATAATTTCTTCCGGACCGAGAATA
TCCTTCAACTGCGGGAACTGGCTCTGAAGGAAGTGGCGCTCCGGGTGGAGAAGAAGGTGGAGAATGAGGTTGTGATGGGT
GTTTCGGTCGGAATCAGGCATGAGAAGTTCATGGCTTGTATCAGTAGTCATGAGAAAACACCCAGGAGGATTATCCGGAA
GGCGGCACGTCTGGCAACACGATATAATACAACTTTTGTTGCTCTCTATGTGCAGACTCCGAGGGAGAGTATGGACCGGA
TTGATCTGGCCAGTCAGCGTTATTTGCTGAATCATTTTAAGCTGGTAGCAGAACTGGGCGGAGAGGTCATCCAGGTGCAG
TCGAAGGATATTCTGGGGAGTATTGTCAAAGTTTGTCGGGACAAGCAAATATCTTCTGTCTGCATGGGAACTCCTAATCT
GAGATTTCCTCATGCCATTTGCTCCATACTCGGATATCGAAAGTTTTTGAATAATTTGTCACAAGCTAATGTAGATTTGA
TTATACTTGCATAA

Upstream 100 bases:

>100_bases
GACCATAGATATAAACTCATGAATTTTTATTATGCAGAAACCCGTGGTGATCGTGATGATTACTACGGGTTGAAATAGTT
TATAAACAGCAATTAATGAA

Downstream 100 bases:

>100_bases
TATTAACCGTATGAACGATATGAATATTAAAACAAAACTGATTCTCGGCATCGGGATGCTGGCGGGAATGATTATTTTGC
TGGTAACACTTTCTGTTGTG

Product: FrrC, osmosensitive K+ channel histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MDMDREQSVQHFLDLIKKSHRGKFKIYIGMIAGVGKSYRMLQEAHELLENGVDVQIGYIETHGRAGTEALMQGLPVIPRR
KIFYKGKELEEMDVDAIIRLHPEIVIVDELAHTNVEGSLNEKRWQDVMTLLDEGINVISAINIQHIESVNEEVQEITGIE
VKERVPDSVLQEADEVVNIDLTAEELISRLKAGKIYRPEKIQTALDNFFRTENILQLRELALKEVALRVEKKVENEVVMG
VSVGIRHEKFMACISSHEKTPRRIIRKAARLATRYNTTFVALYVQTPRESMDRIDLASQRYLLNHFKLVAELGGEVIQVQ
SKDILGSIVKVCRDKQISSVCMGTPNLRFPHAICSILGYRKFLNNLSQANVDLIILA

Sequences:

>Translated_377_residues
MDMDREQSVQHFLDLIKKSHRGKFKIYIGMIAGVGKSYRMLQEAHELLENGVDVQIGYIETHGRAGTEALMQGLPVIPRR
KIFYKGKELEEMDVDAIIRLHPEIVIVDELAHTNVEGSLNEKRWQDVMTLLDEGINVISAINIQHIESVNEEVQEITGIE
VKERVPDSVLQEADEVVNIDLTAEELISRLKAGKIYRPEKIQTALDNFFRTENILQLRELALKEVALRVEKKVENEVVMG
VSVGIRHEKFMACISSHEKTPRRIIRKAARLATRYNTTFVALYVQTPRESMDRIDLASQRYLLNHFKLVAELGGEVIQVQ
SKDILGSIVKVCRDKQISSVCMGTPNLRFPHAICSILGYRKFLNNLSQANVDLIILA
>Mature_377_residues
MDMDREQSVQHFLDLIKKSHRGKFKIYIGMIAGVGKSYRMLQEAHELLENGVDVQIGYIETHGRAGTEALMQGLPVIPRR
KIFYKGKELEEMDVDAIIRLHPEIVIVDELAHTNVEGSLNEKRWQDVMTLLDEGINVISAINIQHIESVNEEVQEITGIE
VKERVPDSVLQEADEVVNIDLTAEELISRLKAGKIYRPEKIQTALDNFFRTENILQLRELALKEVALRVEKKVENEVVMG
VSVGIRHEKFMACISSHEKTPRRIIRKAARLATRYNTTFVALYVQTPRESMDRIDLASQRYLLNHFKLVAELGGEVIQVQ
SKDILGSIVKVCRDKQISSVCMGTPNLRFPHAICSILGYRKFLNNLSQANVDLIILA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=339, Percent_Identity=37.4631268436578, Blast_Score=258, Evalue=5e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42891; Mature: 42891

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMDREQSVQHFLDLIKKSHRGKFKIYIGMIAGVGKSYRMLQEAHELLENGVDVQIGYIE
CCCCHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCHHHHHHHHHHHHHHCCCCEEEEEEE
THGRAGTEALMQGLPVIPRRKIFYKGKELEEMDVDAIIRLHPEIVIVDELAHTNVEGSLN
CCCCCCHHHHHCCCCCCCCCHHEECCCCCCHHCHHHHHEECCCEEEEECHHHCCCCCCCC
EKRWQDVMTLLDEGINVISAINIQHIESVNEEVQEITGIEVKERVPDSVLQEADEVVNID
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHEEEC
LTAEELISRLKAGKIYRPEKIQTALDNFFRTENILQLRELALKEVALRVEKKVENEVVMG
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VSVGIRHEKFMACISSHEKTPRRIIRKAARLATRYNTTFVALYVQTPRESMDRIDLASQR
EEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHH
YLLNHFKLVAELGGEVIQVQSKDILGSIVKVCRDKQISSVCMGTPNLRFPHAICSILGYR
HHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHH
KFLNNLSQANVDLIILA
HHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MDMDREQSVQHFLDLIKKSHRGKFKIYIGMIAGVGKSYRMLQEAHELLENGVDVQIGYIE
CCCCHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCHHHHHHHHHHHHHHCCCCEEEEEEE
THGRAGTEALMQGLPVIPRRKIFYKGKELEEMDVDAIIRLHPEIVIVDELAHTNVEGSLN
CCCCCCHHHHHCCCCCCCCCHHEECCCCCCHHCHHHHHEECCCEEEEECHHHCCCCCCCC
EKRWQDVMTLLDEGINVISAINIQHIESVNEEVQEITGIEVKERVPDSVLQEADEVVNID
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHEEEC
LTAEELISRLKAGKIYRPEKIQTALDNFFRTENILQLRELALKEVALRVEKKVENEVVMG
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VSVGIRHEKFMACISSHEKTPRRIIRKAARLATRYNTTFVALYVQTPRESMDRIDLASQR
EEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHH
YLLNHFKLVAELGGEVIQVQSKDILGSIVKVCRDKQISSVCMGTPNLRFPHAICSILGYR
HHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHH
KFLNNLSQANVDLIILA
HHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9226259; 11466286 [H]