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The map label for this gene is rprX [H]

Identifier: 29347576

GI number: 29347576

Start: 2723807

End: 2725354

Strand: Reverse

Name: rprX [H]

Synonym: BT_2166

Alternate gene names: 29347576

Gene position: 2725354-2723807 (Counterclockwise)

Preceding gene: 29347577

Following gene: 29347575

Centisome position: 43.53

GC content: 40.89

Gene sequence:

>1548_bases
ATGAAGAAGTCAACAATTTGGATATTAAGTATTGTAATGGGGCTTTCTTTCCTTAGTCTGTTGTATTTGCAGGTCAGTTA
TATAGAGGAAATGATGAAAACCCGGAAGGAGCAATTTGATTCGGCTGTGCGCAACAGTCTGGATCAGGTTTCCAAGGATG
TAGAATATGCAGAAACTATGCGCTGGTTGGTTGAGGATATTTCGGATGCTGAAAGAAAAGCGCTGACTGAAAACAATACT
TCATTAGGGCAGAATAATGTAGTTCGGGGGACACAGCGATTTCAAGTGAAGTCACGGGATGGCAAGATTATTTCTGACTT
TGAATTGAGGGTGATGAAGATCAAACCGTCTGAACTTCCTAAAGCGATGGTACGTGGACGAAACACGATTCCTCAGACTT
CTAATTCGATGTTGGAAGCTATCAAGAATCGCTATATGTATCAGCGGGCACTGTTGGATGAAGTAGTGTTGGACATGATT
AGACGTGCGAGTGACAAGTCGATTGGTGATAGAGTACGGTTCAGGGACCTTGACGATTATCTGAAATCGAACTTATATAA
TAATGGTATAGACTTGCCTTATCATTTTGCAGTGATTGACAAGGATGGACGTGAAGTATACCGTTGTGCAGATTATGAAG
CAAAAGGAAGTGAAGAATCCTATCAGCAGGCATTGTTTAAAAACGACCCCCCTGCAAAGATGAGTATTCTGAAAGTGCAT
TTCCCGGGAAAGAAGGACTATATTTTTGATTCGATCAGTTTCATGATTCCGTCACTGATATTTACGTTGGTGTTGTTGGT
GACATTCATCTTTACGATTTATATCGTATTCCGTCAGAAGAAGTTGACGGAAATGAAGAATGACTTTGTCAATAACATGA
CGCATGAGTTCAAGACGCCGATATCAACTATCTCGCTGGCAGCACAGATGTTGAAGGACCCCGCGGTAGCAAAATCACCG
CAAATGTTCCAGCATATATCGGGAGTCATAAATGATGAGACCAAGCGCTTGCGCTTTCAAGTGGAAAAGGTGCTGCAGAT
GTCAATGTTCGACCGGCAGAAGGCAACACTGAAGATGAAGGAGATTGATGCGAATGAACTGATTTCGGGAGTGATCAATA
CCTTTGCACTGAAAGTGGAACGATATAATGGTAAGATAACATCGAACCTTGAGGCAGCCGATCCTGTTATATTTGCAGAT
GAAATGCATCTTACCAATGTGATCTTCAATCTGATGGATAATGCGGTGAAATATAAGAAAGCGGAAGAGGATCTGGAACT
GAAAGTGAAAACGTGGAATGAATCGGGTAAACTGATGATTTCGATACAGGATAACGGTATCGGTATCAAAAAGGAAAACC
TGAAAAAGATATTTGAAAAGTTCTATCGTGTGCATACGGGTAATCTGCACGATGTGAAGGGCTTTGGACTGGGACTGGCT
TATGTGAAGAAAATTATTACCGATCATAAGGGAACCATTAGAGCAGAAAGCGACCTGAACGTAGGAACTAAATTTATTAT
TGCATTACCTTTATTAAAAAATAATTGA

Upstream 100 bases:

>100_bases
TACAACCTAAATAGCTCTTTACGGTTAATTTCCGGGAACTTCCGGTTAAATCAAGTTAATGTGTTAGGAGTGTTAATTAG
GGAGTGTTAATTTTGTTGCT

Downstream 100 bases:

>100_bases
TATGGACGAGAAACTGCGTATTTTATTATGCGAGGATGACGAAAATCTTGGCATGCTTTTAAGAGAATATTTACAGGCAA
AAGGTTATTCTGCTGAGTTA

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MKKSTIWILSIVMGLSFLSLLYLQVSYIEEMMKTRKEQFDSAVRNSLDQVSKDVEYAETMRWLVEDISDAERKALTENNT
SLGQNNVVRGTQRFQVKSRDGKIISDFELRVMKIKPSELPKAMVRGRNTIPQTSNSMLEAIKNRYMYQRALLDEVVLDMI
RRASDKSIGDRVRFRDLDDYLKSNLYNNGIDLPYHFAVIDKDGREVYRCADYEAKGSEESYQQALFKNDPPAKMSILKVH
FPGKKDYIFDSISFMIPSLIFTLVLLVTFIFTIYIVFRQKKLTEMKNDFVNNMTHEFKTPISTISLAAQMLKDPAVAKSP
QMFQHISGVINDETKRLRFQVEKVLQMSMFDRQKATLKMKEIDANELISGVINTFALKVERYNGKITSNLEAADPVIFAD
EMHLTNVIFNLMDNAVKYKKAEEDLELKVKTWNESGKLMISIQDNGIGIKKENLKKIFEKFYRVHTGNLHDVKGFGLGLA
YVKKIITDHKGTIRAESDLNVGTKFIIALPLLKNN

Sequences:

>Translated_515_residues
MKKSTIWILSIVMGLSFLSLLYLQVSYIEEMMKTRKEQFDSAVRNSLDQVSKDVEYAETMRWLVEDISDAERKALTENNT
SLGQNNVVRGTQRFQVKSRDGKIISDFELRVMKIKPSELPKAMVRGRNTIPQTSNSMLEAIKNRYMYQRALLDEVVLDMI
RRASDKSIGDRVRFRDLDDYLKSNLYNNGIDLPYHFAVIDKDGREVYRCADYEAKGSEESYQQALFKNDPPAKMSILKVH
FPGKKDYIFDSISFMIPSLIFTLVLLVTFIFTIYIVFRQKKLTEMKNDFVNNMTHEFKTPISTISLAAQMLKDPAVAKSP
QMFQHISGVINDETKRLRFQVEKVLQMSMFDRQKATLKMKEIDANELISGVINTFALKVERYNGKITSNLEAADPVIFAD
EMHLTNVIFNLMDNAVKYKKAEEDLELKVKTWNESGKLMISIQDNGIGIKKENLKKIFEKFYRVHTGNLHDVKGFGLGLA
YVKKIITDHKGTIRAESDLNVGTKFIIALPLLKNN
>Mature_515_residues
MKKSTIWILSIVMGLSFLSLLYLQVSYIEEMMKTRKEQFDSAVRNSLDQVSKDVEYAETMRWLVEDISDAERKALTENNT
SLGQNNVVRGTQRFQVKSRDGKIISDFELRVMKIKPSELPKAMVRGRNTIPQTSNSMLEAIKNRYMYQRALLDEVVLDMI
RRASDKSIGDRVRFRDLDDYLKSNLYNNGIDLPYHFAVIDKDGREVYRCADYEAKGSEESYQQALFKNDPPAKMSILKVH
FPGKKDYIFDSISFMIPSLIFTLVLLVTFIFTIYIVFRQKKLTEMKNDFVNNMTHEFKTPISTISLAAQMLKDPAVAKSP
QMFQHISGVINDETKRLRFQVEKVLQMSMFDRQKATLKMKEIDANELISGVINTFALKVERYNGKITSNLEAADPVIFAD
EMHLTNVIFNLMDNAVKYKKAEEDLELKVKTWNESGKLMISIQDNGIGIKKENLKKIFEKFYRVHTGNLHDVKGFGLGLA
YVKKIITDHKGTIRAESDLNVGTKFIIALPLLKNN

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=26.8722466960352, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=24.8927038626609, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=24.3697478991597, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=25.3218884120172, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=23.4042553191489, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786783, Length=243, Percent_Identity=25.1028806584362, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790436, Length=274, Percent_Identity=28.4671532846715, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=275, Percent_Identity=22.1818181818182, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=277, Percent_Identity=27.7978339350181, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=26.5486725663717, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=23.175965665236, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=239, Percent_Identity=24.2677824267782, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=24.1379310344828, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=234, Percent_Identity=22.6495726495727, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59287; Mature: 59287

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSTIWILSIVMGLSFLSLLYLQVSYIEEMMKTRKEQFDSAVRNSLDQVSKDVEYAETM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWLVEDISDAERKALTENNTSLGQNNVVRGTQRFQVKSRDGKIISDFELRVMKIKPSELP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEEECCCCCEEECCEEEEEEECHHHHH
KAMVRGRNTIPQTSNSMLEAIKNRYMYQRALLDEVVLDMIRRASDKSIGDRVRFRDLDDY
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHCCHHHH
LKSNLYNNGIDLPYHFAVIDKDGREVYRCADYEAKGSEESYQQALFKNDPPAKMSILKVH
HHHCCCCCCCCCCEEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEE
FPGKKDYIFDSISFMIPSLIFTLVLLVTFIFTIYIVFRQKKLTEMKNDFVNNMTHEFKTP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
ISTISLAAQMLKDPAVAKSPQMFQHISGVINDETKRLRFQVEKVLQMSMFDRQKATLKMK
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEHH
EIDANELISGVINTFALKVERYNGKITSNLEAADPVIFADEMHLTNVIFNLMDNAVKYKK
HCCHHHHHHHHHHHHHHEEECCCCCEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHC
AEEDLELKVKTWNESGKLMISIQDNGIGIKKENLKKIFEKFYRVHTGNLHDVKGFGLGLA
CCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
YVKKIITDHKGTIRAESDLNVGTKFIIALPLLKNN
HHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MKKSTIWILSIVMGLSFLSLLYLQVSYIEEMMKTRKEQFDSAVRNSLDQVSKDVEYAETM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWLVEDISDAERKALTENNTSLGQNNVVRGTQRFQVKSRDGKIISDFELRVMKIKPSELP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEEECCCCCEEECCEEEEEEECHHHHH
KAMVRGRNTIPQTSNSMLEAIKNRYMYQRALLDEVVLDMIRRASDKSIGDRVRFRDLDDY
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHCCHHHH
LKSNLYNNGIDLPYHFAVIDKDGREVYRCADYEAKGSEESYQQALFKNDPPAKMSILKVH
HHHCCCCCCCCCCEEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEE
FPGKKDYIFDSISFMIPSLIFTLVLLVTFIFTIYIVFRQKKLTEMKNDFVNNMTHEFKTP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
ISTISLAAQMLKDPAVAKSPQMFQHISGVINDETKRLRFQVEKVLQMSMFDRQKATLKMK
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEHH
EIDANELISGVINTFALKVERYNGKITSNLEAADPVIFADEMHLTNVIFNLMDNAVKYKK
HCCHHHHHHHHHHHHHHEEECCCCCEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHC
AEEDLELKVKTWNESGKLMISIQDNGIGIKKENLKKIFEKFYRVHTGNLHDVKGFGLGLA
CCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
YVKKIITDHKGTIRAESDLNVGTKFIIALPLLKNN
HHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]