Click here to switch to the map view.

The map label for this gene is fusA [H]

Identifier: 29347577

GI number: 29347577

Start: 2725620

End: 2727776

Strand: Reverse

Name: fusA [H]

Synonym: BT_2167

Alternate gene names: 29347577

Gene position: 2727776-2725620 (Counterclockwise)

Preceding gene: 29347584

Following gene: 29347576

Centisome position: 43.57

GC content: 43.63

Gene sequence:

>2157_bases
ATGAAAGTATATCAGACTAATGAAATTAAGAACATTGCCTTGTTGGGAAGTTCTGGCTCTGGGAAAACCACTCTCGTGGA
AGCGATGCTTTTCGAGAGTGGTGTTATAAAACGTCGCGGATCTGTTGCCGCAAAAAACACAGTTAGCGATTATTTCCCTG
TTGAACAAGAGTATGGTTACTCCGTTTTCTCTACCGTTCTCCACGTAGAATGGAACAATAAAAAGCTTAATATTATAGAC
TGTCCGGGTTCGGACGACTTCGTTGGCAGTACGGTAACTGCACTTAATGTGACCGACACAGCAATTATTCTTCTCAATGG
CCAATACGGCGTCGAAGTCGGTACACAAAATCACTTCCGATACACTGAAAAATTGAATAAGCCAGTTATTTTTCTAGTCA
ACCAGCTTGATAATGAAAAATGCGACTATGATAATATCCTCGAACAACTGAAAGAAGCGTATGGATCTAAGGTGGTTCCC
ATCCAGTATCCTATTGCTACCGGTCCGGGCTTTAATGCCTTGATTGACGTATTGTTGATGAAAAAATATTCGTGGAAACC
CGAAGGCGGTGCTCCTGTGATTGAAGATATTCCGGCAGAAGAAATGGATAAGGCTATGGAAATGCATAAAGCATTGGTAG
AAGCTGCTGCCGAAAATGACGAAGGACTGATGGAGAAATTTTTTGAACAAGATTCTCTGACAGAAGATGAAATGCGTGAA
GGTATCCGTAAGGGATTGATCGCCAGAGGTATGTTCCCAGTATTCTGTGTTTGCGGTGGTAAGGACATGGGCGTTCGCCG
TCTGATGGAATTCCTTGGCAACGTAGTTCCTTTCGTGTCTGAAATGCCGAAAGTGGAAAACACAGATGGTAAGGAAGTAG
CTCCGGACGTAAACGGTCCCGAATCTTTGTATTTCTTCAAAACGAGTGTCGAGCCGCATATCGGTGAAGTATCTTACTTT
AAAGTAATGAGCGGCAAGGTTCGTGAAGGTGATGACTTGCTGAATGCCGACCGTGGTTCGAAAGAACGTATCGCTCAGAT
TTATGTCGTAGCTGGTGGTAACCGTGTGAAAGTGGAAGAACTTCAGGCGGGTGATATCGGTGCTGCCGTAAAACTGAAAG
ATGTGAAGACAGGCAATACACTCAACGGTAAAGACTGCGATTATAAATTCAACTTTATCAAATATCCGAATTCTAAATAT
TCCCGTGCTATTAAACCGGTGAACGAAGCGGACGTGGAAAAGATGATGACCATCCTGAACCGTATGCGTGAAGAAGATCC
GACATGGGTGATCGAGCAATCGAAAGAATTGAAGCAAACGCTGGTACACGGACAGGGAGAATTCCATCTGCGTACGTTGA
AGTGGCGTCTGGAAAATAATGAAAAACTTCAGGTTAAATTTGAGGAACCGAAGATTCCGTATCGTGAAACGATTACGAAG
GCTGCCCGTGCCGATTATCGTCATAAGAAACAATCCGGTGGTGCTGGTCAGTTCGGTGAAGTTCACCTGATCGTTGAACC
TTATAAAGAAGGTATGCCTGTGCCCGATACTTACAAATTCAATGGACAGGAATTTAAGATTACCGTGAGAGGTACTGAAG
AAATTCCATTGGAATGGGGCGGTAAACTGGTATTTATTAACAGTATCGTAGGTGGTTCTATCGATGCCCGTTTCTTGCCT
GCTATTATGAAAGGTATCATGTCACGCCTGGAACAAGGCCCGTTGACAGGTTCGTATGCCCGTGACGTACGTGTAATCGT
ATATGATGGTAAGATGCACCCGGTAGACTCAAATGAAATCTCCTTTATGCTTGCCGGACGTAACGCATTCAGTGAAGCCT
TCAAGAATGCCGGTCCGAAGATTTTGGAACCGATTTATGATGTGGAAGTATTTGTTCCGTCCGACAGAATGGGTGATGTG
ATGGGAGATCTTCAAGGACGCCGTGCCATGATTATGGGTATGAGCAGCGAAAAAGGTTTCGAGAAACTTGTTGCTAAAGT
ACCTTTGAAGGAAATGTCTTCATATTCGACAGCACTTAGCTCACTTACCGGCGGACGTGCTTCATTTATCATGAAGTTTG
CTAGTTATGAACTTGTTCCGACAGATGTTCAGGATAAGTTGATTAAGGATTTTGAAGCTAAACAAACAGAGGAATAA

Upstream 100 bases:

>100_bases
CATAAATATTGCTTTTCCCCCAATAAATCCCTAATTTGCGCATCACTAAATTAATGGTATGCGAGAAACATACTGAGTAA
TTACTAAAATCTTATATATT

Downstream 100 bases:

>100_bases
ACAATAATTCTCTCAAAACTGTTAAAACCGTTGTCTTTTTTAAGTAAAAGACAGCGGTTTTTGTTTAACTATGATTAATA
AAGATGGAAAATCGCAAGGA

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MKVYQTNEIKNIALLGSSGSGKTTLVEAMLFESGVIKRRGSVAAKNTVSDYFPVEQEYGYSVFSTVLHVEWNNKKLNIID
CPGSDDFVGSTVTALNVTDTAIILLNGQYGVEVGTQNHFRYTEKLNKPVIFLVNQLDNEKCDYDNILEQLKEAYGSKVVP
IQYPIATGPGFNALIDVLLMKKYSWKPEGGAPVIEDIPAEEMDKAMEMHKALVEAAAENDEGLMEKFFEQDSLTEDEMRE
GIRKGLIARGMFPVFCVCGGKDMGVRRLMEFLGNVVPFVSEMPKVENTDGKEVAPDVNGPESLYFFKTSVEPHIGEVSYF
KVMSGKVREGDDLLNADRGSKERIAQIYVVAGGNRVKVEELQAGDIGAAVKLKDVKTGNTLNGKDCDYKFNFIKYPNSKY
SRAIKPVNEADVEKMMTILNRMREEDPTWVIEQSKELKQTLVHGQGEFHLRTLKWRLENNEKLQVKFEEPKIPYRETITK
AARADYRHKKQSGGAGQFGEVHLIVEPYKEGMPVPDTYKFNGQEFKITVRGTEEIPLEWGGKLVFINSIVGGSIDARFLP
AIMKGIMSRLEQGPLTGSYARDVRVIVYDGKMHPVDSNEISFMLAGRNAFSEAFKNAGPKILEPIYDVEVFVPSDRMGDV
MGDLQGRRAMIMGMSSEKGFEKLVAKVPLKEMSSYSTALSSLTGGRASFIMKFASYELVPTDVQDKLIKDFEAKQTEE

Sequences:

>Translated_718_residues
MKVYQTNEIKNIALLGSSGSGKTTLVEAMLFESGVIKRRGSVAAKNTVSDYFPVEQEYGYSVFSTVLHVEWNNKKLNIID
CPGSDDFVGSTVTALNVTDTAIILLNGQYGVEVGTQNHFRYTEKLNKPVIFLVNQLDNEKCDYDNILEQLKEAYGSKVVP
IQYPIATGPGFNALIDVLLMKKYSWKPEGGAPVIEDIPAEEMDKAMEMHKALVEAAAENDEGLMEKFFEQDSLTEDEMRE
GIRKGLIARGMFPVFCVCGGKDMGVRRLMEFLGNVVPFVSEMPKVENTDGKEVAPDVNGPESLYFFKTSVEPHIGEVSYF
KVMSGKVREGDDLLNADRGSKERIAQIYVVAGGNRVKVEELQAGDIGAAVKLKDVKTGNTLNGKDCDYKFNFIKYPNSKY
SRAIKPVNEADVEKMMTILNRMREEDPTWVIEQSKELKQTLVHGQGEFHLRTLKWRLENNEKLQVKFEEPKIPYRETITK
AARADYRHKKQSGGAGQFGEVHLIVEPYKEGMPVPDTYKFNGQEFKITVRGTEEIPLEWGGKLVFINSIVGGSIDARFLP
AIMKGIMSRLEQGPLTGSYARDVRVIVYDGKMHPVDSNEISFMLAGRNAFSEAFKNAGPKILEPIYDVEVFVPSDRMGDV
MGDLQGRRAMIMGMSSEKGFEKLVAKVPLKEMSSYSTALSSLTGGRASFIMKFASYELVPTDVQDKLIKDFEAKQTEE
>Mature_718_residues
MKVYQTNEIKNIALLGSSGSGKTTLVEAMLFESGVIKRRGSVAAKNTVSDYFPVEQEYGYSVFSTVLHVEWNNKKLNIID
CPGSDDFVGSTVTALNVTDTAIILLNGQYGVEVGTQNHFRYTEKLNKPVIFLVNQLDNEKCDYDNILEQLKEAYGSKVVP
IQYPIATGPGFNALIDVLLMKKYSWKPEGGAPVIEDIPAEEMDKAMEMHKALVEAAAENDEGLMEKFFEQDSLTEDEMRE
GIRKGLIARGMFPVFCVCGGKDMGVRRLMEFLGNVVPFVSEMPKVENTDGKEVAPDVNGPESLYFFKTSVEPHIGEVSYF
KVMSGKVREGDDLLNADRGSKERIAQIYVVAGGNRVKVEELQAGDIGAAVKLKDVKTGNTLNGKDCDYKFNFIKYPNSKY
SRAIKPVNEADVEKMMTILNRMREEDPTWVIEQSKELKQTLVHGQGEFHLRTLKWRLENNEKLQVKFEEPKIPYRETITK
AARADYRHKKQSGGAGQFGEVHLIVEPYKEGMPVPDTYKFNGQEFKITVRGTEEIPLEWGGKLVFINSIVGGSIDARFLP
AIMKGIMSRLEQGPLTGSYARDVRVIVYDGKMHPVDSNEISFMLAGRNAFSEAFKNAGPKILEPIYDVEVFVPSDRMGDV
MGDLQGRRAMIMGMSSEKGFEKLVAKVPLKEMSSYSTALSSLTGGRASFIMKFASYELVPTDVQDKLIKDFEAKQTEE

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=728, Percent_Identity=30.9065934065934, Blast_Score=325, Evalue=7e-89,
Organism=Homo sapiens, GI19923640, Length=740, Percent_Identity=24.8648648648649, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI25306283, Length=386, Percent_Identity=25.9067357512953, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI25306287, Length=394, Percent_Identity=24.8730964467005, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI217272892, Length=553, Percent_Identity=21.1573236889693, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI217272894, Length=553, Percent_Identity=21.1573236889693, Blast_Score=77, Evalue=8e-14,
Organism=Escherichia coli, GI1789738, Length=719, Percent_Identity=33.7969401947149, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1790835, Length=380, Percent_Identity=22.6315789473684, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI48994988, Length=174, Percent_Identity=24.1379310344828, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17533571, Length=713, Percent_Identity=29.0322580645161, Blast_Score=315, Evalue=7e-86,
Organism=Caenorhabditis elegans, GI17556745, Length=735, Percent_Identity=22.4489795918367, Blast_Score=176, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6323098, Length=730, Percent_Identity=30, Blast_Score=315, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6322359, Length=797, Percent_Identity=24.3412797992472, Blast_Score=228, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24582462, Length=721, Percent_Identity=30.374479889043, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI221458488, Length=748, Percent_Identity=24.1978609625668, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI21357743, Length=562, Percent_Identity=20.6405693950178, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 80255; Mature: 80255

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYQTNEIKNIALLGSSGSGKTTLVEAMLFESGVIKRRGSVAAKNTVSDYFPVEQEYGY
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHCCCCCHHHCCHHHCCCCHHHCCH
SVFSTVLHVEWNNKKLNIIDCPGSDDFVGSTVTALNVTDTAIILLNGQYGVEVGTQNHFR
HEEEEEEEEEECCCEEEEEECCCCCCCCCCEEEEEEECCEEEEEEECCCCEEECCCCCEE
YTEKLNKPVIFLVNQLDNEKCDYDNILEQLKEAYGSKVVPIQYPIATGPGFNALIDVLLM
HHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHH
KKYSWKPEGGAPVIEDIPAEEMDKAMEMHKALVEAAAENDEGLMEKFFEQDSLTEDEMRE
HHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHH
GIRKGLIARGMFPVFCVCGGKDMGVRRLMEFLGNVVPFVSEMPKVENTDGKEVAPDVNGP
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ESLYFFKTSVEPHIGEVSYFKVMSGKVREGDDLLNADRGSKERIAQIYVVAGGNRVKVEE
CEEEEEEECCCCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEEEECCCEEEEEE
LQAGDIGAAVKLKDVKTGNTLNGKDCDYKFNFIKYPNSKYSRAIKPVNEADVEKMMTILN
ECCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCCHHHHHHHHHHHH
RMREEDPTWVIEQSKELKQTLVHGQGEFHLRTLKWRLENNEKLQVKFEEPKIPYRETITK
HHHCCCCCEEECCHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHH
AARADYRHKKQSGGAGQFGEVHLIVEPYKEGMPVPDTYKFNGQEFKITVRGTEEIPLEWG
HHHHHHHHHHCCCCCCCCCEEEEEEECHHCCCCCCCCEEECCCEEEEEEECCCCCCHHHC
GKLVFINSIVGGSIDARFLPAIMKGIMSRLEQGPLTGSYARDVRVIVYDGKMHPVDSNEI
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEECCCCCCCE
SFMLAGRNAFSEAFKNAGPKILEPIYDVEVFVPSDRMGDVMGDLQGRRAMIMGMSSEKGF
EEEEECCHHHHHHHHCCCCHHHCHHHCEEEEECCCHHHHHHHHCCCCEEEEEECCCCHHH
EKLVAKVPLKEMSSYSTALSSLTGGRASFIMKFASYELVPTDVQDKLIKDFEAKQTEE
HHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVYQTNEIKNIALLGSSGSGKTTLVEAMLFESGVIKRRGSVAAKNTVSDYFPVEQEYGY
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHCCCCCHHHCCHHHCCCCHHHCCH
SVFSTVLHVEWNNKKLNIIDCPGSDDFVGSTVTALNVTDTAIILLNGQYGVEVGTQNHFR
HEEEEEEEEEECCCEEEEEECCCCCCCCCCEEEEEEECCEEEEEEECCCCEEECCCCCEE
YTEKLNKPVIFLVNQLDNEKCDYDNILEQLKEAYGSKVVPIQYPIATGPGFNALIDVLLM
HHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHH
KKYSWKPEGGAPVIEDIPAEEMDKAMEMHKALVEAAAENDEGLMEKFFEQDSLTEDEMRE
HHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHH
GIRKGLIARGMFPVFCVCGGKDMGVRRLMEFLGNVVPFVSEMPKVENTDGKEVAPDVNGP
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ESLYFFKTSVEPHIGEVSYFKVMSGKVREGDDLLNADRGSKERIAQIYVVAGGNRVKVEE
CEEEEEEECCCCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEEEECCCEEEEEE
LQAGDIGAAVKLKDVKTGNTLNGKDCDYKFNFIKYPNSKYSRAIKPVNEADVEKMMTILN
ECCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCCHHHHHHHHHHHH
RMREEDPTWVIEQSKELKQTLVHGQGEFHLRTLKWRLENNEKLQVKFEEPKIPYRETITK
HHHCCCCCEEECCHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHH
AARADYRHKKQSGGAGQFGEVHLIVEPYKEGMPVPDTYKFNGQEFKITVRGTEEIPLEWG
HHHHHHHHHHCCCCCCCCCEEEEEEECHHCCCCCCCCEEECCCEEEEEEECCCCCCHHHC
GKLVFINSIVGGSIDARFLPAIMKGIMSRLEQGPLTGSYARDVRVIVYDGKMHPVDSNEI
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEECCCCCCCE
SFMLAGRNAFSEAFKNAGPKILEPIYDVEVFVPSDRMGDVMGDLQGRRAMIMGMSSEKGF
EEEEECCHHHHHHHHCCCCHHHCHHHCEEEEECCCHHHHHHHHCCCCEEEEEECCCCHHH
EKLVAKVPLKEMSSYSTALSSLTGGRASFIMKFASYELVPTDVQDKLIKDFEAKQTEE
HHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA