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The map label for this gene is murA [H]

Identifier: 29347415

GI number: 29347415

Start: 2521264

End: 2522568

Strand: Reverse

Name: murA [H]

Synonym: BT_2005

Alternate gene names: 29347415

Gene position: 2522568-2521264 (Counterclockwise)

Preceding gene: 29347416

Following gene: 29347414

Centisome position: 40.29

GC content: 53.33

Gene sequence:

>1305_bases
ATGGCTTCATTTGTAATTGAAGGAGGACATCGGCTTAGCGGGGAGATTCATCCGCAAGGGGCCAAAAACGAAGTTTTGCA
GATTATCTGTGCCACGTTGCTGACTGCTGAGGAAGTGACGGTGAACAATATACCTGACATTCTGGATGTCAACAATCTGA
TTCAGCTTATGCGGGAGATGGGAGTGACGGTTGCAAAGGAAGGCATTGATACTTACAGTTTTAAGGCGGAGAACGTCGAT
CTGGCTTATTTGGAGAGTGATAAGTTCTTGAAGAAGTGTTCGAGCCTTCGGGGGTCGGTGATGCTGATCGGTCCGATGGT
GGCACGTTTCGGGAAGGCGTTGATCTCGAAGCCGGGCGGAGATAAGATTGGTCGCCGTCGTCTGGACACCCACTTTGTGG
GGATTCAGAATTTGGGAGCTGACTTCCGTTATGACGAGTCGCGGGGCATCTATGAGATAACGGCCGACAGGCTTCAAGGC
AGCTATATGCTGCTTGATGAAGCGTCCGTGACCGGTACAGCCAACATTCTGATGGCTGCCGTACTGGCAAAAGGCACTAC
CACCATTTACAATGCCGCCTGCGAACCCTACTTGCAGCAGCTCTGCCGTATGCTCAACCGGATGGGAGCAAAGATCAGCG
GCATCGCTTCCAATCTGCTCACCATCGAGGGCGTGGAAGAACTGCACGGCACACAGCATACCGTATTGCCCGACATGATT
GAAGTCGGGAGCTTCATCGGCATGGCTGCCATGACCAAAAGCGAAATAACCATTAAAAACGTTTCCTACGAGAACCTCGG
CATCATCCCCGAAAGTTTCCGCCGGTTGGGCATCAAACTGGAGCAGAGGGGAGACGATATCTACGTCCCCGCACAGGAAA
CATACGAAATAGAATCATTCATCGACGGCTCCATCATGACCATTGCCGACGCCCCCTGGCCGGGACTGACACCCGACTTG
CTGAGCGTGATGCTTGTAGTGGCCACCCAAGCCAAAGGAAGCGTACTGATCCATCAGAAGATGTTCGAAAGCCGCCTGTT
CTTTGTAGACAAGCTCATCGACATGGGGGCTCAGATCATCCTTTGCGACCCTCACCGTGCCGTAGTAATCGGACATAACC
ACGGCTTCAAGCTGCGCGGCGCCCGACTGACTTCGCCCGATATCCGTGCGGGGATCGCCCTTCTCATCGCCGCCATGAGC
GCCGAAGGAACCAGCACGATCAGCAATATCGAACAGATAGACCGTGGCTACCAGAACATCGAAGGACGACTTAACGCCAT
CGGCGCCAGAATCACTCGAATATGA

Upstream 100 bases:

>100_bases
CGCGGCGATGTTGTTTGCTGTATGAGATTTTGCACTTGCGGTCTAATACCTAATACTTAATACCTAATACCTAATACTTA
TTACTTAATACTTAAAATAA

Downstream 100 bases:

>100_bases
TAAAGAAAGAAGAAGTATATAAAATCGGACTATTCAACAAGCCGCACGGCATTCACGGCGAGTTGCAGTTTACCTTCACG
GACGATATCTTCGACCGTGT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MASFVIEGGHRLSGEIHPQGAKNEVLQIICATLLTAEEVTVNNIPDILDVNNLIQLMREMGVTVAKEGIDTYSFKAENVD
LAYLESDKFLKKCSSLRGSVMLIGPMVARFGKALISKPGGDKIGRRRLDTHFVGIQNLGADFRYDESRGIYEITADRLQG
SYMLLDEASVTGTANILMAAVLAKGTTTIYNAACEPYLQQLCRMLNRMGAKISGIASNLLTIEGVEELHGTQHTVLPDMI
EVGSFIGMAAMTKSEITIKNVSYENLGIIPESFRRLGIKLEQRGDDIYVPAQETYEIESFIDGSIMTIADAPWPGLTPDL
LSVMLVVATQAKGSVLIHQKMFESRLFFVDKLIDMGAQIILCDPHRAVVIGHNHGFKLRGARLTSPDIRAGIALLIAAMS
AEGTSTISNIEQIDRGYQNIEGRLNAIGARITRI

Sequences:

>Translated_434_residues
MASFVIEGGHRLSGEIHPQGAKNEVLQIICATLLTAEEVTVNNIPDILDVNNLIQLMREMGVTVAKEGIDTYSFKAENVD
LAYLESDKFLKKCSSLRGSVMLIGPMVARFGKALISKPGGDKIGRRRLDTHFVGIQNLGADFRYDESRGIYEITADRLQG
SYMLLDEASVTGTANILMAAVLAKGTTTIYNAACEPYLQQLCRMLNRMGAKISGIASNLLTIEGVEELHGTQHTVLPDMI
EVGSFIGMAAMTKSEITIKNVSYENLGIIPESFRRLGIKLEQRGDDIYVPAQETYEIESFIDGSIMTIADAPWPGLTPDL
LSVMLVVATQAKGSVLIHQKMFESRLFFVDKLIDMGAQIILCDPHRAVVIGHNHGFKLRGARLTSPDIRAGIALLIAAMS
AEGTSTISNIEQIDRGYQNIEGRLNAIGARITRI
>Mature_433_residues
ASFVIEGGHRLSGEIHPQGAKNEVLQIICATLLTAEEVTVNNIPDILDVNNLIQLMREMGVTVAKEGIDTYSFKAENVDL
AYLESDKFLKKCSSLRGSVMLIGPMVARFGKALISKPGGDKIGRRRLDTHFVGIQNLGADFRYDESRGIYEITADRLQGS
YMLLDEASVTGTANILMAAVLAKGTTTIYNAACEPYLQQLCRMLNRMGAKISGIASNLLTIEGVEELHGTQHTVLPDMIE
VGSFIGMAAMTKSEITIKNVSYENLGIIPESFRRLGIKLEQRGDDIYVPAQETYEIESFIDGSIMTIADAPWPGLTPDLL
SVMLVVATQAKGSVLIHQKMFESRLFFVDKLIDMGAQIILCDPHRAVVIGHNHGFKLRGARLTSPDIRAGIALLIAAMSA
EGTSTISNIEQIDRGYQNIEGRLNAIGARITRI

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=442, Percent_Identity=34.1628959276018, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47417; Mature: 47285

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFVIEGGHRLSGEIHPQGAKNEVLQIICATLLTAEEVTVNNIPDILDVNNLIQLMREM
CCCEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
GVTVAKEGIDTYSFKAENVDLAYLESDKFLKKCSSLRGSVMLIGPMVARFGKALISKPGG
CCHHHHCCCCCEEEEECCEEEEEECCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCC
DKIGRRRLDTHFVGIQNLGADFRYDESRGIYEITADRLQGSYMLLDEASVTGTANILMAA
CHHHHHHHHHHEEEHHHCCCCCCCCCCCCEEEEEHHHHCCCEEEEECCCCCCHHHHHHHH
VLAKGTTTIYNAACEPYLQQLCRMLNRMGAKISGIASNLLTIEGVEELHGTQHTVLPDMI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEECHHHHCCCCCCCCHHHH
EVGSFIGMAAMTKSEITIKNVSYENLGIIPESFRRLGIKLEQRGDDIYVPAQETYEIESF
HHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCEEECCCCEEEECCHHHEEHHHH
IDGSIMTIADAPWPGLTPDLLSVMLVVATQAKGSVLIHQKMFESRLFFVDKLIDMGAQII
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEE
LCDPHRAVVIGHNHGFKLRGARLTSPDIRAGIALLIAAMSAEGTSTISNIEQIDRGYQNI
EECCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EGRLNAIGARITRI
HHHHHHHHHHHCCC
>Mature Secondary Structure 
ASFVIEGGHRLSGEIHPQGAKNEVLQIICATLLTAEEVTVNNIPDILDVNNLIQLMREM
CCEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
GVTVAKEGIDTYSFKAENVDLAYLESDKFLKKCSSLRGSVMLIGPMVARFGKALISKPGG
CCHHHHCCCCCEEEEECCEEEEEECCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCC
DKIGRRRLDTHFVGIQNLGADFRYDESRGIYEITADRLQGSYMLLDEASVTGTANILMAA
CHHHHHHHHHHEEEHHHCCCCCCCCCCCCEEEEEHHHHCCCEEEEECCCCCCHHHHHHHH
VLAKGTTTIYNAACEPYLQQLCRMLNRMGAKISGIASNLLTIEGVEELHGTQHTVLPDMI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEECHHHHCCCCCCCCHHHH
EVGSFIGMAAMTKSEITIKNVSYENLGIIPESFRRLGIKLEQRGDDIYVPAQETYEIESF
HHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCEEECCCCEEEECCHHHEEHHHH
IDGSIMTIADAPWPGLTPDLLSVMLVVATQAKGSVLIHQKMFESRLFFVDKLIDMGAQII
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEE
LCDPHRAVVIGHNHGFKLRGARLTSPDIRAGIALLIAAMSAEGTSTISNIEQIDRGYQNI
EECCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EGRLNAIGARITRI
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA