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The map label for this gene is ruvA

Identifier: 29347388

GI number: 29347388

Start: 2488641

End: 2489246

Strand: Reverse

Name: ruvA

Synonym: BT_1978

Alternate gene names: 29347388

Gene position: 2489246-2488641 (Counterclockwise)

Preceding gene: 29347394

Following gene: 29347387

Centisome position: 39.76

GC content: 50.99

Gene sequence:

>606_bases
ATGATAGAATATGTAAGAGGCGAACTTGCCGAACTTAGTCCGGCAACCGCAGTAATCGACTGTAACGGGGTAGGCTATGC
CGCCAATATATCCCTGAATACTTATTCGGCTATTCAGGGGAAGAAAAACTGTAAGTTATATATCTATGAAGCTATTCGGG
AGGACGCGTATGTGCTCTACGGATTTGCCGACAAGCAGGAGCGGGAGATTTTCCTGCTGCTCATTTCCGTGTCGGGCATC
GGAGGCAATACGGCACGTATGATTCTCTCTGCCCTTTCGCCTGCCGAACTGGTGAATGTGATCAGCACCGAAAATGCGAA
TTTGCTGAAAACGGTGAAGGGGATCGGACTGAAAACAGCGCAGCGTGTCATTGTCGACCTGAAAGACAAGATAAAGACGA
TGGGAGCCACCGTGGCAGGAGGAAGCGCTTCTGCCGGAATGCTGCTGCAATCTGCCAGCGTAGAAGTGCAGGAGGAAGCG
GTAGCCGCTCTGACCATGCTTGGCTTTGCCGCCGCGCCTTCGCAGAAAGTGGTACTGGCTATCTTGAAGGAAGAACCGGA
TGCTCCGGTGGAGAAAGTAATAAAACTGGCTTTGAAAAGACTGTAG

Upstream 100 bases:

>100_bases
TGCCTGCATTATTTTTAATTTTTTCACCTCTGACTGCGAGGCGGAAATGTTGCGAAAGTCTTTTCATCTGTGGTGAATTT
GTCTTATCTTTGCAAGGTAT

Downstream 100 bases:

>100_bases
AATAGGTAATAGGTAATAGGTAATAGGTAATAGGGCGTGGAGAAACTAAAACAAGCAACAGAATAATAATGAAACAAGGG
AAAATTTATATGAAAGCATG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIEYVRGELAELSPATAVIDCNGVGYAANISLNTYSAIQGKKNCKLYIYEAIREDAYVLYGFADKQEREIFLLLISVSGI
GGNTARMILSALSPAELVNVISTENANLLKTVKGIGLKTAQRVIVDLKDKIKTMGATVAGGSASAGMLLQSASVEVQEEA
VAALTMLGFAAAPSQKVVLAILKEEPDAPVEKVIKLALKRL

Sequences:

>Translated_201_residues
MIEYVRGELAELSPATAVIDCNGVGYAANISLNTYSAIQGKKNCKLYIYEAIREDAYVLYGFADKQEREIFLLLISVSGI
GGNTARMILSALSPAELVNVISTENANLLKTVKGIGLKTAQRVIVDLKDKIKTMGATVAGGSASAGMLLQSASVEVQEEA
VAALTMLGFAAAPSQKVVLAILKEEPDAPVEKVIKLALKRL
>Mature_201_residues
MIEYVRGELAELSPATAVIDCNGVGYAANISLNTYSAIQGKKNCKLYIYEAIREDAYVLYGFADKQEREIFLLLISVSGI
GGNTARMILSALSPAELVNVISTENANLLKTVKGIGLKTAQRVIVDLKDKIKTMGATVAGGSASAGMLLQSASVEVQEEA
VAALTMLGFAAAPSQKVVLAILKEEPDAPVEKVIKLALKRL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=204, Percent_Identity=34.8039215686275, Blast_Score=116, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_BACTN (Q8A6A7)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_810891.1
- ProteinModelPortal:   Q8A6A7
- SMR:   Q8A6A7
- GeneID:   1076142
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_1978
- NMPDR:   fig|226186.1.peg.1978
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q8A6A7
- ProtClustDB:   PRK00116
- BioCyc:   BTHE226186:BT_1978-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21317; Mature: 21317

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYVRGELAELSPATAVIDCNGVGYAANISLNTYSAIQGKKNCKLYIYEAIREDAYVLY
CCCCCCCHHHHCCCCEEEEEECCCCEEEEEEECCCHHCCCCCCCEEEEEEHHHCCEEEEE
GFADKQEREIFLLLISVSGIGGNTARMILSALSPAELVNVISTENANLLKTVKGIGLKTA
EECCCCCCEEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHCCCHHHH
QRVIVDLKDKIKTMGATVAGGSASAGMLLQSASVEVQEEAVAALTMLGFAAAPSQKVVLA
HHHHHHHHHHHHHHCCEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
ILKEEPDAPVEKVIKLALKRL
EEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIEYVRGELAELSPATAVIDCNGVGYAANISLNTYSAIQGKKNCKLYIYEAIREDAYVLY
CCCCCCCHHHHCCCCEEEEEECCCCEEEEEEECCCHHCCCCCCCEEEEEEHHHCCEEEEE
GFADKQEREIFLLLISVSGIGGNTARMILSALSPAELVNVISTENANLLKTVKGIGLKTA
EECCCCCCEEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHCCCHHHH
QRVIVDLKDKIKTMGATVAGGSASAGMLLQSASVEVQEEAVAALTMLGFAAAPSQKVVLA
HHHHHHHHHHHHHHCCEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
ILKEEPDAPVEKVIKLALKRL
EEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928