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The map label for this gene is fur [H]

Identifier: 29347254

GI number: 29347254

Start: 2316050

End: 2316541

Strand: Reverse

Name: fur [H]

Synonym: BT_1844

Alternate gene names: 29347254

Gene position: 2316541-2316050 (Counterclockwise)

Preceding gene: 29347255

Following gene: 29347253

Centisome position: 37.0

GC content: 41.26

Gene sequence:

>492_bases
ATGATGGAAACTCAAAATGTGAAAGATACAGTAAGGCAGATATTCACAGAATATCTCACGGCGAACGGGCATCGGAAGAC
TCCCGAACGTTACGCCATACTCGAAACTATCTATTCCATCGACGGACACTTCGATATCGATATGCTCTATTCACGGATGA
TGGATCAGGAGAATTTCCGGGTGAGCCGGGCGACTCTTTATAATACTATCATTCTGCTGATCAATGCACGGCTGATCATC
AAGCATCAGTTCGGCACTTCCTCCCAATACGAAAAATCATACAATCGCGAGACGCATCATCATCAGATATGTACTCAATG
TGGTAAAGTGACTGAGTTTCAGAACGAGGAATTGCAGCATGCCATCGAAAATACAAAATTAAGCCGCTTTCAACTTTCGC
ATTACTCCTTATATATATATGGATTGTGCAGCAAGTGCGACAGAGCTAATAAACGGAAAAAAGTCAGTAACAACAATAAA
AAAGAAAAATGA

Upstream 100 bases:

>100_bases
ACGGTTATTACCTATTACCTATTACTTATTACTTATTTCTCAGAAATTCTTTTGCTTTCCACAAAAAAGGCTTAACTTTG
TTCGCGCTAATTTTGTGCTG

Downstream 100 bases:

>100_bases
AAGTAGATGTTCTATTAGGATTACAATGGGGCGACGAAGGTAAAGGCAAAGTAGTCGACGTATTAACACCTAAGTACGAT
GTGGTCGCTCGTTTTCAGGG

Product: iron uptake transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MMETQNVKDTVRQIFTEYLTANGHRKTPERYAILETIYSIDGHFDIDMLYSRMMDQENFRVSRATLYNTIILLINARLII
KHQFGTSSQYEKSYNRETHHHQICTQCGKVTEFQNEELQHAIENTKLSRFQLSHYSLYIYGLCSKCDRANKRKKVSNNNK
KEK

Sequences:

>Translated_163_residues
MMETQNVKDTVRQIFTEYLTANGHRKTPERYAILETIYSIDGHFDIDMLYSRMMDQENFRVSRATLYNTIILLINARLII
KHQFGTSSQYEKSYNRETHHHQICTQCGKVTEFQNEELQHAIENTKLSRFQLSHYSLYIYGLCSKCDRANKRKKVSNNNK
KEK
>Mature_163_residues
MMETQNVKDTVRQIFTEYLTANGHRKTPERYAILETIYSIDGHFDIDMLYSRMMDQENFRVSRATLYNTIILLINARLII
KHQFGTSSQYEKSYNRETHHHQICTQCGKVTEFQNEELQHAIENTKLSRFQLSHYSLYIYGLCSKCDRANKRKKVSNNNK
KEK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 19379; Mature: 19379

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMETQNVKDTVRQIFTEYLTANGHRKTPERYAILETIYSIDGHFDIDMLYSRMMDQENFR
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCH
VSRATLYNTIILLINARLIIKHQFGTSSQYEKSYNRETHHHQICTQCGKVTEFQNEELQH
HHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHH
AIENTKLSRFQLSHYSLYIYGLCSKCDRANKRKKVSNNNKKEK
HHHHCHHHHEEHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMETQNVKDTVRQIFTEYLTANGHRKTPERYAILETIYSIDGHFDIDMLYSRMMDQENFR
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCH
VSRATLYNTIILLINARLIIKHQFGTSSQYEKSYNRETHHHQICTQCGKVTEFQNEELQH
HHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHH
AIENTKLSRFQLSHYSLYIYGLCSKCDRANKRKKVSNNNKKEK
HHHHCHHHHEEHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]