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The map label for this gene is fba [H]

Identifier: 29347101

GI number: 29347101

Start: 2086631

End: 2087635

Strand: Reverse

Name: fba [H]

Synonym: BT_1691

Alternate gene names: 29347101

Gene position: 2087635-2086631 (Counterclockwise)

Preceding gene: 29347106

Following gene: 29347093

Centisome position: 33.35

GC content: 43.68

Gene sequence:

>1005_bases
ATGGTTAATTACAAAGACTTAGGATTGGTAAACACAAGAGACATGTTTGCTAAGGCTATTAAGGGTGGATACGCTATCCC
AGCATTCAACTTCAACAATATGGAACAGATGCAGGCTATCATCAAGGCTGCAGTAGAAACAAAATCTCCGGTGATTCTTC
AGGTTTCTAAAGGTGCTCGTCAGTATGCTAACGCTACTTTGTTGCGTTACATGGCTCAGGGTGCTGTAGAGTACGCAAAA
GAATTAGGTTGCGCACATCCTGAAATCGTTCTTCACCTTGACCACGGAGATACTTTTGAAACTTGCAAATCTTGCATCGA
TTCAGGTTTCTCTTCAGTTATGATCGATGGTTCTCATCTTCCTTACGAAGAAAACGTTGCTTTGACTAAGAAGGTGGTTG
AATACGCTCATCAGTTCGACGTAACAGTTGAAGGTGAACTTGGTGTATTGGCAGGTGTAGAAGATGAAGTTTCTTCTGAC
CACCACACATACACTGACCCTGAAGAAGTAATCGATTTCGCTACTCGTACAGGTTGTGACTCATTGGCTATCTCTATCGG
TACTTCTCACGGTGCTTACAAGTTTACTCCGGAACAGTGCCACATCGATCCGGCTACCGGTCGTATGGTTCCTCCTCCAT
TGGCTTTCGAAGTATTGGATGCTGTAATGGAAAAACTTCCGGGATTCCCTATCGTACTTCACGGATCATCTTCAGTTCCT
GAAGAAGAAGTTGAAACAATCAACAAGTTTGGTGGTGCTCTGAAAGCTGCTATCGGTATTCCTGAAGAAGAATTGCGTAA
AGCTGCCAAGTCTGCTGTTTGCAAAATCAACATCGACTCAGACTCTCGTCTGGCTATGACTGCTGCTATCCGTAAGACTT
TCGCTGAAAAACCTGCTGAATTCGACCCACGTAAGTATCTTGGTCCGGCTCGTGACAACATGGAAAAACTGTACAAGCAC
AAAATCCTTAATGTGCTGGGTTCAGACAACAAATTGGCTGAATAA

Upstream 100 bases:

>100_bases
CCTTTTTCTATTATATTTTTCTTTCCGATGCTCGTTATTCGGTGGATAATGCTTACTTTTGCGTAGAATTTTAATTCACT
AACAATAAACTTTAAACAAA

Downstream 100 bases:

>100_bases
TCACAGATTATCCTATTATATAGAAAGGCTGCAATCGTTTGACGGTTGCAGCCTTTTTTACGTAATATCCTTTATCTGCT
TATTCCGGTTTCTGAGCGGG

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGARQYANATLLRYMAQGAVEYAK
ELGCAHPEIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSD
HHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGRMVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVP
EEEVETINKFGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKH
KILNVLGSDNKLAE

Sequences:

>Translated_334_residues
MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGARQYANATLLRYMAQGAVEYAK
ELGCAHPEIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSD
HHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGRMVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVP
EEEVETINKFGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKH
KILNVLGSDNKLAE
>Mature_334_residues
MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGARQYANATLLRYMAQGAVEYAK
ELGCAHPEIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSD
HHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGRMVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVP
EEEVETINKFGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKH
KILNVLGSDNKLAE

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=334, Percent_Identity=34.4311377245509, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87082041, Length=312, Percent_Identity=33.6538461538462, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1788072, Length=294, Percent_Identity=34.3537414965986, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789293, Length=359, Percent_Identity=23.9554317548747, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 36467; Mature: 36467

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGAR
CCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHH
QYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCC
PYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCD
CCCCCHHHHHHHHHHHHHCCCEECCCCCEEECCCHHHCCCCCCCCCHHHHHHHHHHCCCC
SLAISIGTSHGAYKFTPEQCHIDPATGRMVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVP
CEEEEECCCCCCEEECHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
EEEVETINKFGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRLAMTAAIRKTFAEKPAE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
FDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAE
CCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGAR
CCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHH
QYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCC
PYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCD
CCCCCHHHHHHHHHHHHHCCCEECCCCCEEECCCHHHCCCCCCCCCHHHHHHHHHHCCCC
SLAISIGTSHGAYKFTPEQCHIDPATGRMVPPPLAFEVLDAVMEKLPGFPIVLHGSSSVP
CEEEEECCCCCCEEECHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
EEEVETINKFGGALKAAIGIPEEELRKAAKSAVCKINIDSDSRLAMTAAIRKTFAEKPAE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
FDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAE
CCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]