Click here to switch to the map view.

The map label for this gene is uxuA

Identifier: 29346842

GI number: 29346842

Start: 1762678

End: 1763847

Strand: Reverse

Name: uxuA

Synonym: BT_1432

Alternate gene names: 29346842

Gene position: 1763847-1762678 (Counterclockwise)

Preceding gene: 29346843

Following gene: 29346840

Centisome position: 28.17

GC content: 43.59

Gene sequence:

>1170_bases
ATGTATCTATGTGAACAAACTTGGCGCTGGTATGGTCCGAATGACCCAGTAAGCTTGTGGGATATCAAACAGGCAGGCGC
TACCGGTATAGTAAACGCACTTCATCACATTCCGAATGGTGAAGTGTGGACAGTAGAAGAAATCATGAAGCGTAAGCAAA
TGATTGAAGAAGTGGGTCTGACCTGGTCCGTTGTAGAAAGTGTACCTGTGCACGAACATATCAAAACGCAGACCGGTGAA
TATCTGAAATATATTGAAAACTATAAGGAAAGCATCCGTAATCTGGCTAAATGTGGTGTAATGGTAGTTACTTATAACTT
CATGCCTGTATTAGACTGGACACGTACGGACCTTGCCTATACAATGCCTGACGGTTCTAAAGCTCTTCGCTTTGAGAAAG
CGGCTTTCCTTGCTTTCGACCTCTTTATTCTGAAACGTCCGAATGCGGAGAAAGACTATACTCCGGAAGAAATAGCCAAA
GCAAAAGCCCGTTTCGAACAAATGAGTGAAGACGATAAGAAATTGTTGGTTCGTAATATGATTGCTGGACTTCCGGGATC
GGAAGAAAGTTTCACTGTAGAACAGTTCCAGGAAGCATTGGATCGTTATAATGATATCGATGCTGAGAAACTTCGTTCTA
ACTTGATCTTCTTCCTGAAAGAAATTGCACCTGTGGCTGATGAGGTAGGAGTGAAGCTGGTGATCCATCCGGACGATCCT
CCTTATACAATTTTAGGTTTACCGCGTATTCTAAGTACGGAAGAGGACTTTAAAAAACTGATTGAAGCCGTTCCTAACGA
ATCTAACGGTCTTTGCTTGTGTACAGGTTCTTTCGGTGTACGTGCTGACAATGACCTTGCAGGTATGATGGAGCGTTTTG
GCGATCGTGTCAACTTTGTACACTTGCGTAGTACGCAGCGTGACGAAGAAGGAAACTTCTATGAAGCTAACCACCTGGAA
GGAAATGTAGATATGTACAACGTAATGAAGAGCCTGATTCTTCTGCAACAACGTCGTAAATGTTCTATCGCTATGCGTCC
GGACCACGGTCATCAGATGATTGATGATCTGAAGAAGAAGACAAATCCGGGATATTCCTGCTTAGGCCGCCTGCGTGGAT
TGGCAGAACTTCGCGGTTTGGAAATGGGTATTGCAAAGTCTATTCTATAA

Upstream 100 bases:

>100_bases
ACAGGTACAGTAGCTGTTATCGACGGAGGTTTCGACGCATTCTCCATTTAATACCTATTACTTATTACCTATTACTTATT
ACTTAATACTTATCATAATT

Downstream 100 bases:

>100_bases
GCAGAATTCATAATTAGCAATCTATTTTAAAGACACTACGGCTATTATTGACAGTAATAATAGTGGTAGTGTCTTTTATA
TTGCTCATTTACGGAGCTTT

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MYLCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKQMIEEVGLTWSVVESVPVHEHIKTQTGE
YLKYIENYKESIRNLAKCGVMVVTYNFMPVLDWTRTDLAYTMPDGSKALRFEKAAFLAFDLFILKRPNAEKDYTPEEIAK
AKARFEQMSEDDKKLLVRNMIAGLPGSEESFTVEQFQEALDRYNDIDAEKLRSNLIFFLKEIAPVADEVGVKLVIHPDDP
PYTILGLPRILSTEEDFKKLIEAVPNESNGLCLCTGSFGVRADNDLAGMMERFGDRVNFVHLRSTQRDEEGNFYEANHLE
GNVDMYNVMKSLILLQQRRKCSIAMRPDHGHQMIDDLKKKTNPGYSCLGRLRGLAELRGLEMGIAKSIL

Sequences:

>Translated_389_residues
MYLCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKQMIEEVGLTWSVVESVPVHEHIKTQTGE
YLKYIENYKESIRNLAKCGVMVVTYNFMPVLDWTRTDLAYTMPDGSKALRFEKAAFLAFDLFILKRPNAEKDYTPEEIAK
AKARFEQMSEDDKKLLVRNMIAGLPGSEESFTVEQFQEALDRYNDIDAEKLRSNLIFFLKEIAPVADEVGVKLVIHPDDP
PYTILGLPRILSTEEDFKKLIEAVPNESNGLCLCTGSFGVRADNDLAGMMERFGDRVNFVHLRSTQRDEEGNFYEANHLE
GNVDMYNVMKSLILLQQRRKCSIAMRPDHGHQMIDDLKKKTNPGYSCLGRLRGLAELRGLEMGIAKSIL
>Mature_389_residues
MYLCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKQMIEEVGLTWSVVESVPVHEHIKTQTGE
YLKYIENYKESIRNLAKCGVMVVTYNFMPVLDWTRTDLAYTMPDGSKALRFEKAAFLAFDLFILKRPNAEKDYTPEEIAK
AKARFEQMSEDDKKLLVRNMIAGLPGSEESFTVEQFQEALDRYNDIDAEKLRSNLIFFLKEIAPVADEVGVKLVIHPDDP
PYTILGLPRILSTEEDFKKLIEAVPNESNGLCLCTGSFGVRADNDLAGMMERFGDRVNFVHLRSTQRDEEGNFYEANHLE
GNVDMYNVMKSLILLQQRRKCSIAMRPDHGHQMIDDLKKKTNPGYSCLGRLRGLAELRGLEMGIAKSIL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family

Homologues:

Organism=Escherichia coli, GI1790778, Length=391, Percent_Identity=62.6598465473146, Blast_Score=534, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXUA_BACTN (Q8A7U2)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_810345.1
- ProteinModelPortal:   Q8A7U2
- SMR:   Q8A7U2
- GeneID:   1071708
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_1432
- NMPDR:   fig|226186.1.peg.1432
- HOGENOM:   HBG585927
- OMA:   VHEEIKT
- PhylomeDB:   Q8A7U2
- ProtClustDB:   PRK03906
- BioCyc:   BTHE226186:BT_1432-MONOMER
- BRENDA:   4.2.1.8
- HAMAP:   MF_00106
- InterPro:   IPR004628
- InterPro:   IPR013022
- Gene3D:   G3DSA:3.20.20.150
- PIRSF:   PIRSF016049
- TIGRFAMs:   TIGR00695

Pfam domain/function: PF03786 UxuA; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =4.2.1.8

Molecular weight: Translated: 44461; Mature: 44461

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKQMIEEVGL
CCCCCCCCCCCCCCCCCEEEEHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCC
TWSVVESVPVHEHIKTQTGEYLKYIENYKESIRNLAKCGVMVVTYNFMPVLDWTRTDLAY
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCCCCCCEEE
TMPDGSKALRFEKAAFLAFDLFILKRPNAEKDYTPEEIAKAKARFEQMSEDDKKLLVRNM
ECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
IAGLPGSEESFTVEQFQEALDRYNDIDAEKLRSNLIFFLKEIAPVADEVGVKLVIHPDDP
HHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
PYTILGLPRILSTEEDFKKLIEAVPNESNGLCLCTGSFGVRADNDLAGMMERFGDRVNFV
CEEEEECCHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEE
HLRSTQRDEEGNFYEANHLEGNVDMYNVMKSLILLQQRRKCSIAMRPDHGHQMIDDLKKK
EEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
TNPGYSCLGRLRGLAELRGLEMGIAKSIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYLCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKQMIEEVGL
CCCCCCCCCCCCCCCCCEEEEHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCC
TWSVVESVPVHEHIKTQTGEYLKYIENYKESIRNLAKCGVMVVTYNFMPVLDWTRTDLAY
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCCCCCCEEE
TMPDGSKALRFEKAAFLAFDLFILKRPNAEKDYTPEEIAKAKARFEQMSEDDKKLLVRNM
ECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
IAGLPGSEESFTVEQFQEALDRYNDIDAEKLRSNLIFFLKEIAPVADEVGVKLVIHPDDP
HHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
PYTILGLPRILSTEEDFKKLIEAVPNESNGLCLCTGSFGVRADNDLAGMMERFGDRVNFV
CEEEEECCHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEE
HLRSTQRDEEGNFYEANHLEGNVDMYNVMKSLILLQQRRKCSIAMRPDHGHQMIDDLKKK
EEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
TNPGYSCLGRLRGLAELRGLEMGIAKSIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928