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The map label for this gene is zraR [H]

Identifier: 29346266

GI number: 29346266

Start: 1044639

End: 1046015

Strand: Reverse

Name: zraR [H]

Synonym: BT_0856

Alternate gene names: 29346266

Gene position: 1046015-1044639 (Counterclockwise)

Preceding gene: 29346275

Following gene: 29346265

Centisome position: 16.71

GC content: 43.72

Gene sequence:

>1377_bases
ATGGATGAAGTCAACAAACTAGGAAAGATACTCATTGTAGATGATAACGAAGATGTGCTCTTTGCCCTCAATCTACTACT
CGAACCTTATACAGAAAAGATAAAGGTAGCTACCACTCCCGACCGGATTGAGCATTTTATGACTACCTTTCAGCCCGATC
TTATCTTATTAGATATGAACTTCAGCCGTGATGCAATTAGCGGTCAGGAAGGTTTTGAAAGTCTGAAGCAGATTTTGCAG
ATTGATCCGCAAGCTATTGTCATCTTCATGACTGCATATGCGGATACAGATAAAGCTGTACGGGCCATTAAAGCCGGTGC
AACAGATTTTATCCCCAAACCTTGGGAGAAGGAAAAATTGCTGGCTACTCTCACCTCCGGTATGCGTCTGCGCCAATCTC
AACGGGAGGTAAACATCTTAAAAGAGCAAGTAGAAGCACTCAGCGGACAAAGTTCTCCAGAAGGGGATATTATCGGAGAA
TCTCCGATCATGCAGGAAGTATTTGCAACCATAAACAAACTTAGCAGTACAGATGCCAACATTCTGATTTTGGGAGAAAA
CGGAACGGGAAAAGACGTGATTGCCCGACTGCTATACCGCTACTCCCCCCGATACGGCAAACCTTTTGTTACCATCGACC
TGGGAAGTATCCCCGAACAACTTTTCGAAAGTGAACTGTTCGGCTTTGAAAAGGGAGCATTCACCGATGCAAAAAAGTCA
AAAGCCGGACGGATGGAAGTTGCCACCAATGGTACTTTGTTCCTTGATGAAATCGGTAATCTTTCGCTTCCCATGCAATC
GAAGCTGCTCACTGCGATCGAAAAACGGCAGATCAGCCGTTTAGGAAGCACACAGACCATGCCTATTGATGTTCGTCTGA
TTTGCGCAACGAATGCGGATATCCGCCACATGGTGGATGAAGGAAGTTTCCGTCAGGACTTACTATATCGTATTAATACA
ATTGAAATACATATCCCCCCGCTCCGCGAACGTGGGAATGATATCATTCTGCTTGCTGAATATTTTCTGGACCGTTATGC
ACGCAAATATAAAAAAGAAATGCGTGGCTTGACACGGGAAGCCAAAAATAAGTTGCTGAAATATACGTGGCCAGGTAATG
TACGGGAGTTGCAACATACAATGGAACGTGTCGTAATACTGGGAGACGGTTCTTTATTAAAACCCGAAAACTTCCAGTTC
CACGTCACCCCCAAGCAAAAAAAGGAAGAAGAAATTGTTTTGAACCTTGAACAACTGGAACGGCAAACCATTGAAAAAGC
AATGAAACTTAGTGAAGGGAATATCTCACGTGCTGCTGACTATTTAGGTATTACCCGCTTTGCCTTATATCGCAAACTTG
AAAAACTAGGCTTATGA

Upstream 100 bases:

>100_bases
TTTAGTGCGCAATCGCACATACAACACATGATTATTATCCATATCTTTGCCCTTGCATTAAAACTTTAGGATAAGTAACG
AATCATATACCCCATACCCT

Downstream 100 bases:

>100_bases
AACGATTTGCATTCAGAGTAATTTTACATATTTTACTGATAGTATTGTTTTCTATCGGCAGCTACCTGCTATTTCAAAAG
CAGTTATGGTTCAGTACTAC

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MDEVNKLGKILIVDDNEDVLFALNLLLEPYTEKIKVATTPDRIEHFMTTFQPDLILLDMNFSRDAISGQEGFESLKQILQ
IDPQAIVIFMTAYADTDKAVRAIKAGATDFIPKPWEKEKLLATLTSGMRLRQSQREVNILKEQVEALSGQSSPEGDIIGE
SPIMQEVFATINKLSSTDANILILGENGTGKDVIARLLYRYSPRYGKPFVTIDLGSIPEQLFESELFGFEKGAFTDAKKS
KAGRMEVATNGTLFLDEIGNLSLPMQSKLLTAIEKRQISRLGSTQTMPIDVRLICATNADIRHMVDEGSFRQDLLYRINT
IEIHIPPLRERGNDIILLAEYFLDRYARKYKKEMRGLTREAKNKLLKYTWPGNVRELQHTMERVVILGDGSLLKPENFQF
HVTPKQKKEEEIVLNLEQLERQTIEKAMKLSEGNISRAADYLGITRFALYRKLEKLGL

Sequences:

>Translated_458_residues
MDEVNKLGKILIVDDNEDVLFALNLLLEPYTEKIKVATTPDRIEHFMTTFQPDLILLDMNFSRDAISGQEGFESLKQILQ
IDPQAIVIFMTAYADTDKAVRAIKAGATDFIPKPWEKEKLLATLTSGMRLRQSQREVNILKEQVEALSGQSSPEGDIIGE
SPIMQEVFATINKLSSTDANILILGENGTGKDVIARLLYRYSPRYGKPFVTIDLGSIPEQLFESELFGFEKGAFTDAKKS
KAGRMEVATNGTLFLDEIGNLSLPMQSKLLTAIEKRQISRLGSTQTMPIDVRLICATNADIRHMVDEGSFRQDLLYRINT
IEIHIPPLRERGNDIILLAEYFLDRYARKYKKEMRGLTREAKNKLLKYTWPGNVRELQHTMERVVILGDGSLLKPENFQF
HVTPKQKKEEEIVLNLEQLERQTIEKAMKLSEGNISRAADYLGITRFALYRKLEKLGL
>Mature_458_residues
MDEVNKLGKILIVDDNEDVLFALNLLLEPYTEKIKVATTPDRIEHFMTTFQPDLILLDMNFSRDAISGQEGFESLKQILQ
IDPQAIVIFMTAYADTDKAVRAIKAGATDFIPKPWEKEKLLATLTSGMRLRQSQREVNILKEQVEALSGQSSPEGDIIGE
SPIMQEVFATINKLSSTDANILILGENGTGKDVIARLLYRYSPRYGKPFVTIDLGSIPEQLFESELFGFEKGAFTDAKKS
KAGRMEVATNGTLFLDEIGNLSLPMQSKLLTAIEKRQISRLGSTQTMPIDVRLICATNADIRHMVDEGSFRQDLLYRINT
IEIHIPPLRERGNDIILLAEYFLDRYARKYKKEMRGLTREAKNKLLKYTWPGNVRELQHTMERVVILGDGSLLKPENFQF
HVTPKQKKEEEIVLNLEQLERQTIEKAMKLSEGNISRAADYLGITRFALYRKLEKLGL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=448, Percent_Identity=37.5, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1788550, Length=465, Percent_Identity=35.2688172043011, Blast_Score=294, Evalue=7e-81,
Organism=Escherichia coli, GI1790299, Length=479, Percent_Identity=35.0730688935282, Blast_Score=290, Evalue=9e-80,
Organism=Escherichia coli, GI87082117, Length=344, Percent_Identity=39.8255813953488, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI1788905, Length=409, Percent_Identity=32.2738386308068, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=40.1253918495298, Blast_Score=234, Evalue=6e-63,
Organism=Escherichia coli, GI87082152, Length=339, Percent_Identity=38.9380530973451, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789087, Length=336, Percent_Identity=38.0952380952381, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1786524, Length=317, Percent_Identity=38.1703470031546, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=38.9240506329114, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1787583, Length=336, Percent_Identity=33.0357142857143, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI87081858, Length=284, Percent_Identity=28.169014084507, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789828, Length=242, Percent_Identity=34.297520661157, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52019; Mature: 52019

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEVNKLGKILIVDDNEDVLFALNLLLEPYTEKIKVATTPDRIEHFMTTFQPDLILLDMN
CCCHHCCCEEEEEECCCCHHHHHHHHHCCCHHCEEEECCHHHHHHHHHHCCCCEEEEEEC
FSRDAISGQEGFESLKQILQIDPQAIVIFMTAYADTDKAVRAIKAGATDFIPKPWEKEKL
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHH
LATLTSGMRLRQSQREVNILKEQVEALSGQSSPEGDIIGESPIMQEVFATINKLSSTDAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCE
ILILGENGTGKDVIARLLYRYSPRYGKPFVTIDLGSIPEQLFESELFGFEKGAFTDAKKS
EEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHC
KAGRMEVATNGTLFLDEIGNLSLPMQSKLLTAIEKRQISRLGSTQTMPIDVRLICATNAD
CCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCH
IRHMVDEGSFRQDLLYRINTIEIHIPPLRERGNDIILLAEYFLDRYARKYKKEMRGLTRE
HHHHHCCCCHHHHHHHEEEEEEEECCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
AKNKLLKYTWPGNVRELQHTMERVVILGDGSLLKPENFQFHVTPKQKKEEEIVLNLEQLE
HHCCEEEEECCCCHHHHHHHHHEEEEECCCCEECCCCCEEEECCCCCCCHHHEEEHHHHH
RQTIEKAMKLSEGNISRAADYLGITRFALYRKLEKLGL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDEVNKLGKILIVDDNEDVLFALNLLLEPYTEKIKVATTPDRIEHFMTTFQPDLILLDMN
CCCHHCCCEEEEEECCCCHHHHHHHHHCCCHHCEEEECCHHHHHHHHHHCCCCEEEEEEC
FSRDAISGQEGFESLKQILQIDPQAIVIFMTAYADTDKAVRAIKAGATDFIPKPWEKEKL
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHH
LATLTSGMRLRQSQREVNILKEQVEALSGQSSPEGDIIGESPIMQEVFATINKLSSTDAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCE
ILILGENGTGKDVIARLLYRYSPRYGKPFVTIDLGSIPEQLFESELFGFEKGAFTDAKKS
EEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHC
KAGRMEVATNGTLFLDEIGNLSLPMQSKLLTAIEKRQISRLGSTQTMPIDVRLICATNAD
CCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCH
IRHMVDEGSFRQDLLYRINTIEIHIPPLRERGNDIILLAEYFLDRYARKYKKEMRGLTRE
HHHHHCCCCHHHHHHHEEEEEEEECCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
AKNKLLKYTWPGNVRELQHTMERVVILGDGSLLKPENFQFHVTPKQKKEEEIVLNLEQLE
HHCCEEEEECCCCHHHHHHHHHEEEEECCCCEECCCCCEEEECCCCCCCHHHEEEHHHHH
RQTIEKAMKLSEGNISRAADYLGITRFALYRKLEKLGL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]