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The map label for this gene is oxaA

Identifier: 29345999

GI number: 29345999

Start: 727714

End: 729570

Strand: Reverse

Name: oxaA

Synonym: BT_0589

Alternate gene names: 29345999

Gene position: 729570-727714 (Counterclockwise)

Preceding gene: 29346000

Following gene: 29345998

Centisome position: 11.65

GC content: 45.88

Gene sequence:

>1857_bases
ATGGATAAAAACACCATTACAGGTCTCGTTTTAATAGGTATATTATTGGTAGGATTCAGTTATCTGAGCCGTCCAAGCGA
GGAGCAGATAGCTGCGCAGAAGAAATACTACGATTCTATTGCCGTGGTGCAACAGCAGCAGGAAGCGCTGAAAGCAAAAA
CAGAAGCCGCACTCGCCAATGAAAACAAAGGTGCAGCGGCGGCAGCAGATTCTTCTGCCCTGTTTTTCAACGCGATGCAT
GGAACTGATTCCAAAGTAAGCATCCAGAACAGCGTAGCGGAAATCACTTTCACTACGAAAGGCGGACGGGTATATTCGGC
TATGCTGAAAGAATACAAAGGACAGGACAAGACAAACCCTGTCGTACTGTTCGACGGTGATGATGCTACCATGAGTTTCA
ACTTCTACAACAAGCAAGGAGCCATCCAGACAAAGGACTATTACTTCGAAGCTGTCAATAAGACAGACAGCAGCGTAACT
ATGCGTCTGGCTGCGGACAACGCCAGCTACATCGATTTTATCTATACGCTGAAACCGAACAGCTACCTGATGAACTTTGA
AATCAAAGCAACAGGCATGGAAGGCAAACTGGCCAGTACGGAGTATGTAGACATCGACTGGACACAGCGTGCACGCCAGC
TGGAAAAGGGATTCACTTACGAAAACCGCCTCTCAGAGCTGACTTATAAGGTAAAAGGTGACAATGTAGATAATCTGTCG
GCTGCCAAGGATGACGAAAAGGATCTGGGCAATACAGCGATAGACTGGGTAGCATTCAAAAACCAGTTCTTCTCTTCTGT
ATTCATTGCAGACCAGGACTTCAACAAGGTTTCTGTGAAGTCAAGAATGGAACAACAAGGAAGCGGATATATCAAGGATT
ATTCTGCAGAAATGAGTACCTTCTTCGATCCGAGCGGAAAACAACCGACAGAAATGTACTTCTACTTTGGCCCGAACCAC
TTCAAGACCTTGAAGGCACTGGACAAAGGACGTACAGAGAAATGGGAACTTAACAGACTGGTATATCTGGGCTGGCCGTT
AATCCGCTGGATCAACCAGTTTATCACGATCAACGTATTCGACTGGCTGTCGGGCTGGGGCTTGAGCATGGGTATCGTAC
TGTTGATTCTGACAATTATGGTGAAGGTGGTAGTTTACCCTGCTACCTGGAAAACATACATGTCTTCTGCCAAGATGCGT
GTATTGAAACCGAAAATCGACGAGATCAACAAGAAGTATCCGAAGCAGGAAGATGCGATGAAGAAACAGCAGGAGGTGAT
GAGCCTTTACAGCCAGTATGGCGTGAGCCCGATGGGCGGTTGTCTGCCAATGTTATTGCAGTTCCCGATCTTGATGGCAT
TGTTCATGTTCGTACCGAGCGCTATCGAGTTACGTCAGCAGAGCTTCTTGTGGGCGGACGACTTGTCCACTTACGACGCG
TTCATCACATTCCCGTTCCATATCCCGTTCCTGGGCAACCATCTCAGCTTGTTCTGCTTGCTGATGACGGTAACCAACAT
CCTGAACACAAAGTATACAATGACGATGCAGGATACAGGAGCACAACCGCAAATGGCTGCGATGAAATGGATGATGTATC
TGATGCCGATTATGTTCCTGTTCGTACTGAACGACTATCCTTCGGGATTGAACTATTATTATTTCGTGTCAACACTGATT
AGTGTAGGAACCATGATTTTGTTGCGTAAAACTACAGACGAAACAAAATTACTGGCTATTCTGGAAGCTAAGAAAAAAGA
CCCGAAACAAATGAAAAAGACCGGATTTGCTGCACGCCTGGAAGCTATGCAAAAGCAACAGGAACAGTTACAGCAGCAAA
AACAGAATAAACGATAA

Upstream 100 bases:

>100_bases
CTTTCGTGAAGGCAGCCATCGAGAACGAGAAGAATTGACAATTGACAGTTGACAATTGACAATTTATTATTCAAAAATTT
ATAATTCATAATTAATAGGA

Downstream 100 bases:

>100_bases
GAAATTATCCGAAGATATATTCTGAGAAAGCCGGGCAACCGAAAGGGGTTTGTCCGGCTTTCTTTCTCTAAAAAACAAAC
TTAATATGAAGACAAAATAT

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MDKNTITGLVLIGILLVGFSYLSRPSEEQIAAQKKYYDSIAVVQQQQEALKAKTEAALANENKGAAAAADSSALFFNAMH
GTDSKVSIQNSVAEITFTTKGGRVYSAMLKEYKGQDKTNPVVLFDGDDATMSFNFYNKQGAIQTKDYYFEAVNKTDSSVT
MRLAADNASYIDFIYTLKPNSYLMNFEIKATGMEGKLASTEYVDIDWTQRARQLEKGFTYENRLSELTYKVKGDNVDNLS
AAKDDEKDLGNTAIDWVAFKNQFFSSVFIADQDFNKVSVKSRMEQQGSGYIKDYSAEMSTFFDPSGKQPTEMYFYFGPNH
FKTLKALDKGRTEKWELNRLVYLGWPLIRWINQFITINVFDWLSGWGLSMGIVLLILTIMVKVVVYPATWKTYMSSAKMR
VLKPKIDEINKKYPKQEDAMKKQQEVMSLYSQYGVSPMGGCLPMLLQFPILMALFMFVPSAIELRQQSFLWADDLSTYDA
FITFPFHIPFLGNHLSLFCLLMTVTNILNTKYTMTMQDTGAQPQMAAMKWMMYLMPIMFLFVLNDYPSGLNYYYFVSTLI
SVGTMILLRKTTDETKLLAILEAKKKDPKQMKKTGFAARLEAMQKQQEQLQQQKQNKR

Sequences:

>Translated_618_residues
MDKNTITGLVLIGILLVGFSYLSRPSEEQIAAQKKYYDSIAVVQQQQEALKAKTEAALANENKGAAAAADSSALFFNAMH
GTDSKVSIQNSVAEITFTTKGGRVYSAMLKEYKGQDKTNPVVLFDGDDATMSFNFYNKQGAIQTKDYYFEAVNKTDSSVT
MRLAADNASYIDFIYTLKPNSYLMNFEIKATGMEGKLASTEYVDIDWTQRARQLEKGFTYENRLSELTYKVKGDNVDNLS
AAKDDEKDLGNTAIDWVAFKNQFFSSVFIADQDFNKVSVKSRMEQQGSGYIKDYSAEMSTFFDPSGKQPTEMYFYFGPNH
FKTLKALDKGRTEKWELNRLVYLGWPLIRWINQFITINVFDWLSGWGLSMGIVLLILTIMVKVVVYPATWKTYMSSAKMR
VLKPKIDEINKKYPKQEDAMKKQQEVMSLYSQYGVSPMGGCLPMLLQFPILMALFMFVPSAIELRQQSFLWADDLSTYDA
FITFPFHIPFLGNHLSLFCLLMTVTNILNTKYTMTMQDTGAQPQMAAMKWMMYLMPIMFLFVLNDYPSGLNYYYFVSTLI
SVGTMILLRKTTDETKLLAILEAKKKDPKQMKKTGFAARLEAMQKQQEQLQQQKQNKR
>Mature_618_residues
MDKNTITGLVLIGILLVGFSYLSRPSEEQIAAQKKYYDSIAVVQQQQEALKAKTEAALANENKGAAAAADSSALFFNAMH
GTDSKVSIQNSVAEITFTTKGGRVYSAMLKEYKGQDKTNPVVLFDGDDATMSFNFYNKQGAIQTKDYYFEAVNKTDSSVT
MRLAADNASYIDFIYTLKPNSYLMNFEIKATGMEGKLASTEYVDIDWTQRARQLEKGFTYENRLSELTYKVKGDNVDNLS
AAKDDEKDLGNTAIDWVAFKNQFFSSVFIADQDFNKVSVKSRMEQQGSGYIKDYSAEMSTFFDPSGKQPTEMYFYFGPNH
FKTLKALDKGRTEKWELNRLVYLGWPLIRWINQFITINVFDWLSGWGLSMGIVLLILTIMVKVVVYPATWKTYMSSAKMR
VLKPKIDEINKKYPKQEDAMKKQQEVMSLYSQYGVSPMGGCLPMLLQFPILMALFMFVPSAIELRQQSFLWADDLSTYDA
FITFPFHIPFLGNHLSLFCLLMTVTNILNTKYTMTMQDTGAQPQMAAMKWMMYLMPIMFLFVLNDYPSGLNYYYFVSTLI
SVGTMILLRKTTDETKLLAILEAKKKDPKQMKKTGFAARLEAMQKQQEQLQQQKQNKR

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=519, Percent_Identity=25.4335260115607, Blast_Score=133, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_BACTN (Q8AA76)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_809502.1
- GeneID:   1072196
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_0589
- NMPDR:   fig|226186.1.peg.589
- HOGENOM:   HBG307913
- OMA:   YVFRSSI
- PhylomeDB:   Q8AA76
- ProtClustDB:   PRK01318
- BioCyc:   BTHE226186:BT_0589-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 70525; Mature: 70525

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91fcc48)-; HASH(0xce7d18c)-; HASH(0xb3c4ce4)-; HASH(0xd049cb8)-; HASH(0xd679404)-; HASH(0xcd2f500)-; HASH(0xcc4587c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNTITGLVLIGILLVGFSYLSRPSEEQIAAQKKYYDSIAVVQQQQEALKAKTEAALAN
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ENKGAAAAADSSALFFNAMHGTDSKVSIQNSVAEITFTTKGGRVYSAMLKEYKGQDKTNP
CCCCCCCCCCCCEEEEEEECCCCCCEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCC
VVLFDGDDATMSFNFYNKQGAIQTKDYYFEAVNKTDSSVTMRLAADNASYIDFIYTLKPN
EEEECCCCCEEEEEEECCCCCEEEHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEECCC
SYLMNFEIKATGMEGKLASTEYVDIDWTQRARQLEKGFTYENRLSELTYKVKGDNVDNLS
CEEEEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHCEEEECCCCCCCCC
AAKDDEKDLGNTAIDWVAFKNQFFSSVFIADQDFNKVSVKSRMEQQGSGYIKDYSAEMST
CCCCCHHHCCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCEEHHHHHHHH
FFDPSGKQPTEMYFYFGPNHFKTLKALDKGRTEKWELNRLVYLGWPLIRWINQFITINVF
CCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEECCEEEEECCHHHHHHHHHEEEEHH
DWLSGWGLSMGIVLLILTIMVKVVVYPATWKTYMSSAKMRVLKPKIDEINKKYPKQEDAM
HHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHEEECCCHHHHHHHCCCHHHHH
KKQQEVMSLYSQYGVSPMGGCLPMLLQFPILMALFMFVPSAIELRQQSFLWADDLSTYDA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCEECCCCCCCCE
FITFPFHIPFLGNHLSLFCLLMTVTNILNTKYTMTMQDTGAQPQMAAMKWMMYLMPIMFL
EEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
FVLNDYPSGLNYYYFVSTLISVGTMILLRKTTDETKLLAILEAKKKDPKQMKKTGFAARL
HHHHCCCCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
EAMQKQQEQLQQQKQNKR
HHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MDKNTITGLVLIGILLVGFSYLSRPSEEQIAAQKKYYDSIAVVQQQQEALKAKTEAALAN
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ENKGAAAAADSSALFFNAMHGTDSKVSIQNSVAEITFTTKGGRVYSAMLKEYKGQDKTNP
CCCCCCCCCCCCEEEEEEECCCCCCEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCC
VVLFDGDDATMSFNFYNKQGAIQTKDYYFEAVNKTDSSVTMRLAADNASYIDFIYTLKPN
EEEECCCCCEEEEEEECCCCCEEEHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEECCC
SYLMNFEIKATGMEGKLASTEYVDIDWTQRARQLEKGFTYENRLSELTYKVKGDNVDNLS
CEEEEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHCEEEECCCCCCCCC
AAKDDEKDLGNTAIDWVAFKNQFFSSVFIADQDFNKVSVKSRMEQQGSGYIKDYSAEMST
CCCCCHHHCCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCEEHHHHHHHH
FFDPSGKQPTEMYFYFGPNHFKTLKALDKGRTEKWELNRLVYLGWPLIRWINQFITINVF
CCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEECCEEEEECCHHHHHHHHHEEEEHH
DWLSGWGLSMGIVLLILTIMVKVVVYPATWKTYMSSAKMRVLKPKIDEINKKYPKQEDAM
HHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHEEECCCHHHHHHHCCCHHHHH
KKQQEVMSLYSQYGVSPMGGCLPMLLQFPILMALFMFVPSAIELRQQSFLWADDLSTYDA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCEECCCCCCCCE
FITFPFHIPFLGNHLSLFCLLMTVTNILNTKYTMTMQDTGAQPQMAAMKWMMYLMPIMFL
EEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
FVLNDYPSGLNYYYFVSTLISVGTMILLRKTTDETKLLAILEAKKKDPKQMKKTGFAARL
HHHHCCCCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
EAMQKQQEQLQQQKQNKR
HHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12663928