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The map label for this gene is tkt [H]

Identifier: 29345757

GI number: 29345757

Start: 415536

End: 417545

Strand: Reverse

Name: tkt [H]

Synonym: BT_0347

Alternate gene names: 29345757

Gene position: 417545-415536 (Counterclockwise)

Preceding gene: 29345758

Following gene: 29345756

Centisome position: 6.67

GC content: 47.41

Gene sequence:

>2010_bases
ATGAACGATAATAAACTTATGAATCGTGCAGCGGATAACATCCGTATTCTTGCTGCTTCAATGGTTGAGAAAGCCAATTC
CGGTCACCCGGGTGGCGCCATGGGTGGTGCTGACTTTGTAAATGTACTCTTCTCTGAGTTTCTAGTATACGATCCTGAAA
ATCCGCGTTGGGAAGGTCGTGACCGTTTCTTCCTTGATCCGGGTCATATGTCTCCGATGCTCTATTCTACATTGGCATTG
ACAGGTAAGTTCACTTTGGACGAACTAAAAGAATTTCGCCAATGGGGAAGCCCTACTCCGGGACATCCGGAAGTAGACAT
CATGCGTGGTATCGAAAATACTTCCGGTCCGCTGGGACAGGGACATACTTTCGCTGTAGGTGCCGCTATCGCAGCTAAAT
TCCTGAAAGCACGCTTCAATGAAGTAATGAATCAGACTATTTACGCATACATTTCCGATGGTGGTATTCAGGAAGAAATC
TCTCAGGGTGCCGGACGCATTGCCGGTGCATTGGGACTGGACAACCTGATCATGTTCTACGACTCCAACGATATTCAGCT
TTCTACAGAAACGAAAGATGTAACCGTTGAAGACACTGCCATGAAATATGAAGCATGGGGATGGAACGTACTCAGCATCA
ATGGTAATGATCCTGACGAAATCCGTGCAGCTATCAAAGAAGCTCAGACAGAAAAAGAGCGCCCGACTCTGATTATCGGT
AAAACCGTTATGGGTAAAGGCGCACGCAAAGCAGACGGTAGCAGCTACGAAGCCAACTGTGCTACACACGGCGCTCCACT
CGGTGGCGACGCCTATGTAAATACAATCAAGAATTTGGGTGGCGATCCTGTCAATCCGTTCGTGATTTTCCCGGAAGTAG
CCGAACTGTATGCAAAGAGAGCAGCAGAATTAAAGAAAATCGTAGCTGAAAGATATGCAAAGAAGGCCAAATGGACCAAA
GCCAATCCGGAACTGGCAGCTAAACTGGAAGCATTCTTCTCCGGCAAAGCTCCTAAAGTAGACTGGGCTGCCATCGAACA
AAAAGCAGGTACTGCCACTCGTGCCGCTTCTGCAACTGTTCTGGGTGCTCTTGCAATGCAGGTAGAAAATATGATCGTTG
CTTCTGCCGACCTTTCTAACTCTGACAAGACTGACGGTTTCCTGAAGAAAACTCATTCTTTCAAGAAGGGCGATTTCAGC
GGTGCATTCTTCCAGGCCGGTGTATCTGAATTATCAATGGCTTGTATCTGTATCGGTATGTCACTTCACGGTGGTGTGAT
CGCTGCTTGCGGTACCTTCTTCGTATTCTCCGACTATATGAAACCTGCCGTACGTATGGCTGCTCTGATGGAACAGCCTG
TGAAGTTCATCTGGACTCATGATGCATTCCGCGTAGGTGAAGACGGTCCTACTCATGAACCGGTAGAACAGGAAGCTCAA
ATCCGCCTGATGGAGAAACTGAAAAACCACAAGGGACACAACTCTATGTTGGTACTTCGTCCGGCTGATGCGGAAGAAAC
GACTATCGCATGGAAACTTGCCATGGAAAATATGTCTACTCCGACAGGTCTGATCTTCTCCCGTCAGAATATCGCTAACC
TGCCTGCCGGAACTGATTACGAACAAGCAGCCAAGGGTGCTTATATCGTAGCCGGTTCAGACGAAAATCCGGATGTAATC
CTGGTAGCTTCAGGTTCCGAAGTGTCTACTTTGGTAGCCGGTACAGAGTTGCTTCGCAAGGATGGCGTAAAAGTTCGTAT
CGTATCTGCACCATCAGAAGGTCTGTTCCGCAGCCAGTCTAAGGAATATCAGGAATCAGTTCTTCCGGCTGATGCCAAGA
TATTCGGTCTTACTGCCGGTTTGCCTGTCACTCTTCAAGGTCTGGTAGGTTGCCACGGCAAAGTATGGGGATTGGAATCT
TTCGGTTTCTCTGCTCCTTACACAGTATTGGATGAAAAACTTGGATTTACTGCCGAGAACGTATATAATCAGGTAAAAGC
AATGATTTAA

Upstream 100 bases:

>100_bases
GGTTAATTACACATAAAGAGCTATCTTTGCCAACATTATGAGAAATATGCCAAGTAATTGGCACATTGACAGACTAGCAA
ATCTATTAATTATTAAAGAT

Downstream 100 bases:

>100_bases
TGAAAACAATTGGATTAGCATGCGACCACGCCGGTTTTGAACTAAAAGAATATGTTCGCGGCTGGCTGGAAGTAAAAGGC
TGGGCTTACAAAGATTTCGG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MNDNKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGRDRFFLDPGHMSPMLYSTLAL
TGKFTLDELKEFRQWGSPTPGHPEVDIMRGIENTSGPLGQGHTFAVGAAIAAKFLKARFNEVMNQTIYAYISDGGIQEEI
SQGAGRIAGALGLDNLIMFYDSNDIQLSTETKDVTVEDTAMKYEAWGWNVLSINGNDPDEIRAAIKEAQTEKERPTLIIG
KTVMGKGARKADGSSYEANCATHGAPLGGDAYVNTIKNLGGDPVNPFVIFPEVAELYAKRAAELKKIVAERYAKKAKWTK
ANPELAAKLEAFFSGKAPKVDWAAIEQKAGTATRAASATVLGALAMQVENMIVASADLSNSDKTDGFLKKTHSFKKGDFS
GAFFQAGVSELSMACICIGMSLHGGVIAACGTFFVFSDYMKPAVRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
IRLMEKLKNHKGHNSMLVLRPADAEETTIAWKLAMENMSTPTGLIFSRQNIANLPAGTDYEQAAKGAYIVAGSDENPDVI
LVASGSEVSTLVAGTELLRKDGVKVRIVSAPSEGLFRSQSKEYQESVLPADAKIFGLTAGLPVTLQGLVGCHGKVWGLES
FGFSAPYTVLDEKLGFTAENVYNQVKAMI

Sequences:

>Translated_669_residues
MNDNKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGRDRFFLDPGHMSPMLYSTLAL
TGKFTLDELKEFRQWGSPTPGHPEVDIMRGIENTSGPLGQGHTFAVGAAIAAKFLKARFNEVMNQTIYAYISDGGIQEEI
SQGAGRIAGALGLDNLIMFYDSNDIQLSTETKDVTVEDTAMKYEAWGWNVLSINGNDPDEIRAAIKEAQTEKERPTLIIG
KTVMGKGARKADGSSYEANCATHGAPLGGDAYVNTIKNLGGDPVNPFVIFPEVAELYAKRAAELKKIVAERYAKKAKWTK
ANPELAAKLEAFFSGKAPKVDWAAIEQKAGTATRAASATVLGALAMQVENMIVASADLSNSDKTDGFLKKTHSFKKGDFS
GAFFQAGVSELSMACICIGMSLHGGVIAACGTFFVFSDYMKPAVRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
IRLMEKLKNHKGHNSMLVLRPADAEETTIAWKLAMENMSTPTGLIFSRQNIANLPAGTDYEQAAKGAYIVAGSDENPDVI
LVASGSEVSTLVAGTELLRKDGVKVRIVSAPSEGLFRSQSKEYQESVLPADAKIFGLTAGLPVTLQGLVGCHGKVWGLES
FGFSAPYTVLDEKLGFTAENVYNQVKAMI
>Mature_669_residues
MNDNKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGRDRFFLDPGHMSPMLYSTLAL
TGKFTLDELKEFRQWGSPTPGHPEVDIMRGIENTSGPLGQGHTFAVGAAIAAKFLKARFNEVMNQTIYAYISDGGIQEEI
SQGAGRIAGALGLDNLIMFYDSNDIQLSTETKDVTVEDTAMKYEAWGWNVLSINGNDPDEIRAAIKEAQTEKERPTLIIG
KTVMGKGARKADGSSYEANCATHGAPLGGDAYVNTIKNLGGDPVNPFVIFPEVAELYAKRAAELKKIVAERYAKKAKWTK
ANPELAAKLEAFFSGKAPKVDWAAIEQKAGTATRAASATVLGALAMQVENMIVASADLSNSDKTDGFLKKTHSFKKGDFS
GAFFQAGVSELSMACICIGMSLHGGVIAACGTFFVFSDYMKPAVRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
IRLMEKLKNHKGHNSMLVLRPADAEETTIAWKLAMENMSTPTGLIFSRQNIANLPAGTDYEQAAKGAYIVAGSDENPDVI
LVASGSEVSTLVAGTELLRKDGVKVRIVSAPSEGLFRSQSKEYQESVLPADAKIFGLTAGLPVTLQGLVGCHGKVWGLES
FGFSAPYTVLDEKLGFTAENVYNQVKAMI

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=595, Percent_Identity=26.3865546218487, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI4507521, Length=595, Percent_Identity=26.3865546218487, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI133778974, Length=601, Percent_Identity=24.9584026622296, Blast_Score=119, Evalue=8e-27,
Organism=Escherichia coli, GI1788808, Length=669, Percent_Identity=40.50822122571, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI48994911, Length=676, Percent_Identity=39.3491124260355, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1786304, Length=204, Percent_Identity=27.9411764705882, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17539652, Length=587, Percent_Identity=26.9165247018739, Blast_Score=162, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6325331, Length=681, Percent_Identity=38.0323054331865, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6319593, Length=678, Percent_Identity=35.3982300884956, Blast_Score=347, Evalue=4e-96,
Organism=Drosophila melanogaster, GI45551847, Length=588, Percent_Identity=26.3605442176871, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI45550715, Length=588, Percent_Identity=26.3605442176871, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24666278, Length=595, Percent_Identity=25.3781512605042, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24645119, Length=559, Percent_Identity=26.2969588550984, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72259; Mature: 72259

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGR
CCCHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCC
DRFFLDPGHMSPMLYSTLALTGKFTLDELKEFRQWGSPTPGHPEVDIMRGIENTSGPLGQ
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCC
GHTFAVGAAIAAKFLKARFNEVMNQTIYAYISDGGIQEEISQGAGRIAGALGLDNLIMFY
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHCHHHHHHHCCCCCEEEEE
DSNDIQLSTETKDVTVEDTAMKYEAWGWNVLSINGNDPDEIRAAIKEAQTEKERPTLIIG
ECCCEEEEECCCCEEEEHHHEEEEECCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEE
KTVMGKGARKADGSSYEANCATHGAPLGGDAYVNTIKNLGGDPVNPFVIFPEVAELYAKR
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECHHHHHHHHHH
AAELKKIVAERYAKKAKWTKANPELAAKLEAFFSGKAPKVDWAAIEQKAGTATRAASATV
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHH
LGALAMQVENMIVASADLSNSDKTDGFLKKTHSFKKGDFSGAFFQAGVSELSMACICIGM
HHHHHHHHHHHEEEECCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHCHHHHHHHHHHEEH
SLHGGVIAACGTFFVFSDYMKPAVRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCEECCCCCCCCCCHHHHHH
IRLMEKLKNHKGHNSMLVLRPADAEETTIAWKLAMENMSTPTGLIFSRQNIANLPAGTDY
HHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEHHCCCCCCCEEEECCCCCCCCCCCCH
EQAAKGAYIVAGSDENPDVILVASGSEVSTLVAGTELLRKDGVKVRIVSAPSEGLFRSQS
HHHHCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
KEYQESVLPADAKIFGLTAGLPVTLQGLVGCHGKVWGLESFGFSAPYTVLDEKLGFTAEN
HHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCEEECCHHCCCCCCHHHHHHHCCCCHHH
VYNQVKAMI
HHHHHHHCC
>Mature Secondary Structure
MNDNKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPRWEGR
CCCHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCC
DRFFLDPGHMSPMLYSTLALTGKFTLDELKEFRQWGSPTPGHPEVDIMRGIENTSGPLGQ
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCC
GHTFAVGAAIAAKFLKARFNEVMNQTIYAYISDGGIQEEISQGAGRIAGALGLDNLIMFY
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHCHHHHHHHCCCCCEEEEE
DSNDIQLSTETKDVTVEDTAMKYEAWGWNVLSINGNDPDEIRAAIKEAQTEKERPTLIIG
ECCCEEEEECCCCEEEEHHHEEEEECCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEE
KTVMGKGARKADGSSYEANCATHGAPLGGDAYVNTIKNLGGDPVNPFVIFPEVAELYAKR
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECHHHHHHHHHH
AAELKKIVAERYAKKAKWTKANPELAAKLEAFFSGKAPKVDWAAIEQKAGTATRAASATV
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHH
LGALAMQVENMIVASADLSNSDKTDGFLKKTHSFKKGDFSGAFFQAGVSELSMACICIGM
HHHHHHHHHHHEEEECCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHCHHHHHHHHHHEEH
SLHGGVIAACGTFFVFSDYMKPAVRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCEECCCCCCCCCCHHHHHH
IRLMEKLKNHKGHNSMLVLRPADAEETTIAWKLAMENMSTPTGLIFSRQNIANLPAGTDY
HHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEHHCCCCCCCEEEECCCCCCCCCCCCH
EQAAKGAYIVAGSDENPDVILVASGSEVSTLVAGTELLRKDGVKVRIVSAPSEGLFRSQS
HHHHCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
KEYQESVLPADAKIFGLTAGLPVTLQGLVGCHGKVWGLESFGFSAPYTVLDEKLGFTAEN
HHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCEEECCHHCCCCCCHHHHHHHCCCCHHH
VYNQVKAMI
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]