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The map label for this gene is prmA

Identifier: 29345724

GI number: 29345724

Start: 377857

End: 378699

Strand: Reverse

Name: prmA

Synonym: BT_0314

Alternate gene names: 29345724

Gene position: 378699-377857 (Counterclockwise)

Preceding gene: 29345730

Following gene: 29345713

Centisome position: 6.05

GC content: 43.42

Gene sequence:

>843_bases
ATGAAGTATTTTGAGTTCACATTCCATACAAGTCCATGCACAGAAACAGTAAATGACGTACTGGCTGCCGTATTAGGTGA
AGCCGGATTTGAAAGTTTTGTTGAAAGCGAAGGCGGACTGACTGCATACATACAACAGGCATTATGCGATGAAAATACAA
TAAAAAATGCAATAACCGAATTTCCTCTGCCCGATACGGAGATCACTTATACATACGTTGAAGCGGAAGACAAAGACTGG
AACGAAGAATGGGAAAAAAATTTCTTTCAGCCGATTGTGATCGATAACCGATGTGTTATCCATAGTACCTTCCATAAAGA
TGTACCCCAGGCAACTTATGATATCGTTATCAATCCGCAAATGGCTTTCGGCACGGGACATCATGAAACGACAAGCCTCA
TCATCGGGGAGTTACTGGACAATGAGTTGAAAGATAAATCACTTCTGGATATGGGCTGTGGAACTTCGATCTTAGCTATT
CTCGCCCGCATGCGGGGAGCACGCCCATGTATCGCTATTGACATTGACGAATGGTGTGTACGAAACTCTATTGAGAACAT
TGAATTAAACCACGTAGACGACATCGCCGTTTCACAAGGAGATGCCTCATCGCTTGTTGGCAAAGGGCCCTTTGATATCA
TCATCGCTAATATAAACCGGAATATTCTATTGAACGACATGAAGCAATACGTTGCCTGCATGCACCCGGGATCGGAACTT
TATATGAGTGGATTTTATGTGGACGACATTCCTTTCATCCGCCGGGAAGCAGAAAAGAACGGACTGACCTTCGTACATCA
TAAGGAGAAAAACCGCTGGGCAGCAGTGAAGTTCACATATTAA

Upstream 100 bases:

>100_bases
GAAGAGATTCGCCACTCTAGGGAGATTTTCCCCAAAGGATAATAGGGAAATCCCTATTTCTAACTATCTTTGCAAAAGAT
TCACCAAATTAAAAACAACT

Downstream 100 bases:

>100_bases
GCATTAATCTTCCTTATCTGTTTCAAGAAGACACAGACCACGTATCTTTAAAAGACAGCATATATTTGTAGTAGAGATAA
GATGTACGAGATGCTCATCT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKYFEFTFHTSPCTETVNDVLAAVLGEAGFESFVESEGGLTAYIQQALCDENTIKNAITEFPLPDTEITYTYVEAEDKDW
NEEWEKNFFQPIVIDNRCVIHSTFHKDVPQATYDIVINPQMAFGTGHHETTSLIIGELLDNELKDKSLLDMGCGTSILAI
LARMRGARPCIAIDIDEWCVRNSIENIELNHVDDIAVSQGDASSLVGKGPFDIIIANINRNILLNDMKQYVACMHPGSEL
YMSGFYVDDIPFIRREAEKNGLTFVHHKEKNRWAAVKFTY

Sequences:

>Translated_280_residues
MKYFEFTFHTSPCTETVNDVLAAVLGEAGFESFVESEGGLTAYIQQALCDENTIKNAITEFPLPDTEITYTYVEAEDKDW
NEEWEKNFFQPIVIDNRCVIHSTFHKDVPQATYDIVINPQMAFGTGHHETTSLIIGELLDNELKDKSLLDMGCGTSILAI
LARMRGARPCIAIDIDEWCVRNSIENIELNHVDDIAVSQGDASSLVGKGPFDIIIANINRNILLNDMKQYVACMHPGSEL
YMSGFYVDDIPFIRREAEKNGLTFVHHKEKNRWAAVKFTY
>Mature_280_residues
MKYFEFTFHTSPCTETVNDVLAAVLGEAGFESFVESEGGLTAYIQQALCDENTIKNAITEFPLPDTEITYTYVEAEDKDW
NEEWEKNFFQPIVIDNRCVIHSTFHKDVPQATYDIVINPQMAFGTGHHETTSLIIGELLDNELKDKSLLDMGCGTSILAI
LARMRGARPCIAIDIDEWCVRNSIENIELNHVDDIAVSQGDASSLVGKGPFDIIIANINRNILLNDMKQYVACMHPGSEL
YMSGFYVDDIPFIRREAEKNGLTFVHHKEKNRWAAVKFTY

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=149, Percent_Identity=37.5838926174497, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_BACTN (Q8AAZ8)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_809227.1
- ProteinModelPortal:   Q8AAZ8
- SMR:   Q8AAZ8
- GeneID:   1075493
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_0314
- NMPDR:   fig|226186.1.peg.314
- HOGENOM:   HBG405568
- OMA:   AIDIDDW
- ProtClustDB:   PRK00517
- BioCyc:   BTHE226186:BT_0314-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31658; Mature: 31658

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYFEFTFHTSPCTETVNDVLAAVLGEAGFESFVESEGGLTAYIQQALCDENTIKNAITE
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHH
FPLPDTEITYTYVEAEDKDWNEEWEKNFFQPIVIDNRCVIHSTFHKDVPQATYDIVINPQ
CCCCCCEEEEEEEECCCCCCHHHHHHCCCCCEEECCEEEEEECHHCCCCCCEEEEEECCC
MAFGTGHHETTSLIIGELLDNELKDKSLLDMGCGTSILAILARMRGARPCIAIDIDEWCV
EEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHHH
RNSIENIELNHVDDIAVSQGDASSLVGKGPFDIIIANINRNILLNDMKQYVACMHPGSEL
HCCCCCEECCCCCCCEECCCCHHHHCCCCCEEEEEEECCCCEEHHHHHHHHHHCCCCHHH
YMSGFYVDDIPFIRREAEKNGLTFVHHKEKNRWAAVKFTY
EEECEEECCCHHHHHHHHCCCCEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MKYFEFTFHTSPCTETVNDVLAAVLGEAGFESFVESEGGLTAYIQQALCDENTIKNAITE
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHH
FPLPDTEITYTYVEAEDKDWNEEWEKNFFQPIVIDNRCVIHSTFHKDVPQATYDIVINPQ
CCCCCCEEEEEEEECCCCCCHHHHHHCCCCCEEECCEEEEEECHHCCCCCCEEEEEECCC
MAFGTGHHETTSLIIGELLDNELKDKSLLDMGCGTSILAILARMRGARPCIAIDIDEWCV
EEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHHH
RNSIENIELNHVDDIAVSQGDASSLVGKGPFDIIIANINRNILLNDMKQYVACMHPGSEL
HCCCCCEECCCCCCCEECCCCHHHHCCCCCEEEEEEECCCCEEHHHHHHHHHHCCCCHHH
YMSGFYVDDIPFIRREAEKNGLTFVHHKEKNRWAAVKFTY
EEECEEECCCHHHHHHHHCCCCEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928