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The map label for this gene is allB [H]

Identifier: 29345660

GI number: 29345660

Start: 275479

End: 276816

Strand: Reverse

Name: allB [H]

Synonym: BT_0250

Alternate gene names: 29345660

Gene position: 276816-275479 (Counterclockwise)

Preceding gene: 29345661

Following gene: 29345659

Centisome position: 4.42

GC content: 46.94

Gene sequence:

>1338_bases
ATGAAACGTATACTGATAAAAAACGCCGTAATTGTCAACGAAGGAAGAAAAGTTCCGGGATCTGTTGTTATTGAAGGTGA
GAAGATTGCTGAGATCTTAGTTGACGGACAAGAGGCTGCCATGCCTTGTGACGAAACGATTGACGCATCCGGCTGTTATC
TTTTGCCGGGGGCTATTGACGAGCACGTACATTTCCGCGATCCGGGGCTGACTCATAAAGCAGATATCACAACGGAAAGC
CATGCCGCGGCAGCCGGAGGAGTTACCTCGATTATGGATATGCCGAACACAAATCCTCAGACCACAACTTTGGAGGCACT
GAATGACAAACTGGCTTTGCTGGCGGAAAAATCATCTGTCAACTTCTCCTGTTATTTCGGAGCGACTAACAATAATTATC
CGTTATTCAGTCAGCTGGACAAAAACCGGGTATGTGGAGTGAAGTTATTTATGGGTTCCAGTACGGGAAATATGCTGGTA
GACCGGATGGCAAGTCTGCGCAACATCTTTGGAGGTACGGATTTACTGATTGCAGCACACTGTGAAGATCAGGGAATCAT
CAAAGAGAATACGGATAAATATAAAAAAGAATATGGTGACGATGTACCTTTGGCACTTCATCCGGTCATCCGCTCGGAAG
AGGCTTGCTACCGTTCTTCCGCTTTGGCGGTACAATTGGCACGCGAGACCAATGCGCGTCTGCATATTATGCATATTTCT
ACTGCCAAAGAACTGAGTTTATTCTCCAAAGCACCTTTGGCAGAGAAGCGTATTACCGCCGAAGCGTGTGTGTCTCATCT
AATTTTTACCGAAGAAGATTATCAGACCTTAGGAGCGCGCATCAAATGTAATCCTGCCATCAAAACGGCAGAAGACCGGA
AGGCTTTGCAGGAGGCAGTCAACAGCGGTCTGATCGACGCTATTGCGACCGACCATGCTCCGCACTCCTTGAGCGAAAAA
GAAGGGGGCGCATTAAAAGTCATGTCCGGCATGCCGACCATACAATTCTCTTTGGTCAGTATGCTCGAATTGGCAGACAA
GGGTGCTTTCAGCATCGAAAAGGTAGTAGAGAAGATGTCCCATGCCCCTGCACAAATGTACGAGATACGCAATCGCGGAT
TTATCCGGAAAGGATATCAAGCGGATCTGGTTCTGGTTCGCCCCGACAGTGAGTGGACTGTTACCACAGACTGCATCCTG
AGCAAATGTAAATGGAGCCCGCTGGAAGGTCATACTTTCCACTGGAAGGTAGAAAAAACATTTGTGAACGGTCATCTGTT
ATATAACAACGGAACCATTGACGAGAATTATCGTGGACAGGAGTTAAGATTCAGATAA

Upstream 100 bases:

>100_bases
TGGGAACCTCCAAGATGAACAGCAGTATCTTTGGAGAAGCCATATTCGGAGTGATCAAGTTAAAAATAAATAGTTGGTTC
CATAAATTCCCGCAAAAGAA

Downstream 100 bases:

>100_bases
ACAGCAACTCGTCACTTATAAACATATGATTTTATCTTATAAGATACATAACGTCGCCCCCTACATCAATTGGATTTACT
TTTTCCATGCATGGGGATTC

Product: dihydroorotase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKRILIKNAVIVNEGRKVPGSVVIEGEKIAEILVDGQEAAMPCDETIDASGCYLLPGAIDEHVHFRDPGLTHKADITTES
HAAAAGGVTSIMDMPNTNPQTTTLEALNDKLALLAEKSSVNFSCYFGATNNNYPLFSQLDKNRVCGVKLFMGSSTGNMLV
DRMASLRNIFGGTDLLIAAHCEDQGIIKENTDKYKKEYGDDVPLALHPVIRSEEACYRSSALAVQLARETNARLHIMHIS
TAKELSLFSKAPLAEKRITAEACVSHLIFTEEDYQTLGARIKCNPAIKTAEDRKALQEAVNSGLIDAIATDHAPHSLSEK
EGGALKVMSGMPTIQFSLVSMLELADKGAFSIEKVVEKMSHAPAQMYEIRNRGFIRKGYQADLVLVRPDSEWTVTTDCIL
SKCKWSPLEGHTFHWKVEKTFVNGHLLYNNGTIDENYRGQELRFR

Sequences:

>Translated_445_residues
MKRILIKNAVIVNEGRKVPGSVVIEGEKIAEILVDGQEAAMPCDETIDASGCYLLPGAIDEHVHFRDPGLTHKADITTES
HAAAAGGVTSIMDMPNTNPQTTTLEALNDKLALLAEKSSVNFSCYFGATNNNYPLFSQLDKNRVCGVKLFMGSSTGNMLV
DRMASLRNIFGGTDLLIAAHCEDQGIIKENTDKYKKEYGDDVPLALHPVIRSEEACYRSSALAVQLARETNARLHIMHIS
TAKELSLFSKAPLAEKRITAEACVSHLIFTEEDYQTLGARIKCNPAIKTAEDRKALQEAVNSGLIDAIATDHAPHSLSEK
EGGALKVMSGMPTIQFSLVSMLELADKGAFSIEKVVEKMSHAPAQMYEIRNRGFIRKGYQADLVLVRPDSEWTVTTDCIL
SKCKWSPLEGHTFHWKVEKTFVNGHLLYNNGTIDENYRGQELRFR
>Mature_445_residues
MKRILIKNAVIVNEGRKVPGSVVIEGEKIAEILVDGQEAAMPCDETIDASGCYLLPGAIDEHVHFRDPGLTHKADITTES
HAAAAGGVTSIMDMPNTNPQTTTLEALNDKLALLAEKSSVNFSCYFGATNNNYPLFSQLDKNRVCGVKLFMGSSTGNMLV
DRMASLRNIFGGTDLLIAAHCEDQGIIKENTDKYKKEYGDDVPLALHPVIRSEEACYRSSALAVQLARETNARLHIMHIS
TAKELSLFSKAPLAEKRITAEACVSHLIFTEEDYQTLGARIKCNPAIKTAEDRKALQEAVNSGLIDAIATDHAPHSLSEK
EGGALKVMSGMPTIQFSLVSMLELADKGAFSIEKVVEKMSHAPAQMYEIRNRGFIRKGYQADLVLVRPDSEWTVTTDCIL
SKCKWSPLEGHTFHWKVEKTFVNGHLLYNNGTIDENYRGQELRFR

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=394, Percent_Identity=26.6497461928934, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI4503379, Length=451, Percent_Identity=22.8381374722838, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4503377, Length=449, Percent_Identity=21.380846325167, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786722, Length=442, Percent_Identity=28.0542986425339, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI87082175, Length=456, Percent_Identity=24.780701754386, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI193204318, Length=381, Percent_Identity=29.1338582677165, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322218, Length=443, Percent_Identity=25.2821670428894, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24642586, Length=380, Percent_Identity=27.3684210526316, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI18859883, Length=466, Percent_Identity=23.3905579399142, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221377917, Length=460, Percent_Identity=24.1304347826087, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17137462, Length=451, Percent_Identity=24.1685144124169, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644287, Length=304, Percent_Identity=25.6578947368421, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49044; Mature: 49044

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00483 DIHYDROOROTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILIKNAVIVNEGRKVPGSVVIEGEKIAEILVDGQEAAMPCDETIDASGCYLLPGAID
CCEEEEECEEEEECCCCCCCCEEEECHHHEEHHCCCHHHCCCCCCCCCCCCCEEECCCCC
EHVHFRDPGLTHKADITTESHAAAAGGVTSIMDMPNTNPQTTTLEALNDKLALLAEKSSV
CCEEECCCCCCCEECCCCCCCHHHCCCHHHHHCCCCCCCCCEEHHHHCCCEEEEEECCCC
NFSCYFGATNNNYPLFSQLDKNRVCGVKLFMGSSTGNMLVDRMASLRNIFGGTDLLIAAH
EEEEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEE
CEDQGIIKENTDKYKKEYGDDVPLALHPVIRSEEACYRSSALAVQLARETNARLHIMHIS
CCCCCCCCCCHHHHHHHCCCCCCEEEEHHHCCCHHHHHCCHHEEEEECCCCCEEEEEEEC
TAKELSLFSKAPLAEKRITAEACVSHLIFTEEDYQTLGARIKCNPAIKTAEDRKALQEAV
CHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCCCCCHHHHHHHHHHH
NSGLIDAIATDHAPHSLSEKEGGALKVMSGMPTIQFSLVSMLELADKGAFSIEKVVEKMS
CCCCEEHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HAPAQMYEIRNRGFIRKGYQADLVLVRPDSEWTVTTDCILSKCKWSPLEGHTFHWKVEKT
CCHHHHHHHHCCCCEECCCCCCEEEECCCCCEEEEHHHHHHHCCCCCCCCCEEEEEEEEE
FVNGHLLYNNGTIDENYRGQELRFR
EECCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRILIKNAVIVNEGRKVPGSVVIEGEKIAEILVDGQEAAMPCDETIDASGCYLLPGAID
CCEEEEECEEEEECCCCCCCCEEEECHHHEEHHCCCHHHCCCCCCCCCCCCCEEECCCCC
EHVHFRDPGLTHKADITTESHAAAAGGVTSIMDMPNTNPQTTTLEALNDKLALLAEKSSV
CCEEECCCCCCCEECCCCCCCHHHCCCHHHHHCCCCCCCCCEEHHHHCCCEEEEEECCCC
NFSCYFGATNNNYPLFSQLDKNRVCGVKLFMGSSTGNMLVDRMASLRNIFGGTDLLIAAH
EEEEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEE
CEDQGIIKENTDKYKKEYGDDVPLALHPVIRSEEACYRSSALAVQLARETNARLHIMHIS
CCCCCCCCCCHHHHHHHCCCCCCEEEEHHHCCCHHHHHCCHHEEEEECCCCCEEEEEEEC
TAKELSLFSKAPLAEKRITAEACVSHLIFTEEDYQTLGARIKCNPAIKTAEDRKALQEAV
CHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCCCCCHHHHHHHHHHH
NSGLIDAIATDHAPHSLSEKEGGALKVMSGMPTIQFSLVSMLELADKGAFSIEKVVEKMS
CCCCEEHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HAPAQMYEIRNRGFIRKGYQADLVLVRPDSEWTVTTDCILSKCKWSPLEGHTFHWKVEKT
CCHHHHHHHHCCCCEECCCCCCEEEECCCCCEEEEHHHHHHHCCCCCCCCCEEEEEEEEE
FVNGHLLYNNGTIDENYRGQELRFR
EECCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA