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The map label for this gene is chuR

Identifier: 29345648

GI number: 29345648

Start: 262126

End: 263370

Strand: Reverse

Name: chuR

Synonym: BT_0238

Alternate gene names: 29345648

Gene position: 263370-262126 (Counterclockwise)

Preceding gene: 29345653

Following gene: 29345647

Centisome position: 4.21

GC content: 42.97

Gene sequence:

>1245_bases
ATGAAAGCAACAACTTATGCACCTTTTGCCAAACCGCTTTATGTCATGGTAAAGCCCGTGGGAGCCGTATGCAACCTCGC
ATGCGAATACTGCTATTATTTGGAAAAGGCGAATCTATACAAAGAAAACCCGAAACATGTAATGAGCGATGAGCTACTGG
AAAAGTTTATCGACGAGTATATCAACTCTCAAACCATGCCTCAAGTGCTTTTTACCTGGCACGGTGGAGAAACGCTGATG
CGTCCGCTTTCTTTTTATAAAAAGGCGATGGAGCTGCAAAAGAAATACGCCCGCGGACGTACGATTGACAATTGTATCCA
GACGAATGGAACCTTGCTTACAGACGAATGGTGCGAGTTCTTCCGTGAAAACAACTGGCTGGTAGGGGTTTCCATTGATG
GCCCGCAAGAGTTTCATGACGAATATCGCAAAAATAAGATGGGCAAACCTTCTTTCGTCAAAGTGATGCAAGGGATCAAT
CTCCTGAAAAAACATGGAGTAGAATGGAACGCTATGGCTGTTGTGAACGATTTCAATGCCGAATATCCATTAGACTTTTA
TAATTTCTTCAAAGAAATAGATTGCCATTATATTCAGTTCGCTCCGATTGTTGAACGCATTGTTTCACATCAGGACGGTC
GTCATCTTGCCTCTCTGGCAGAAGGTAAAGAAGGGGCATTGGCTGATTTTTCCGTAAGTCCGGAACAATGGGGTAACTTT
CTCTGTACAATTTTTGATGAATGGGTAAAAGAAGATGTGGGCAAATTCTTCATACAGATATTCGATTCCACATTGGCTAA
CTGGATGGGCGAGCAACCGGGCGTATGTACAATGGCGAAGCATTGCGGACATGCCGGCGTTATGGAATTCAACGGAGACG
TATACTCTTGTGACCACTTCGTATTCCCGGAATATAAATTGGGAAATATCTATAGCCAAACTTTGGTGGAAATGATGCAT
AGTGAACGACAGCATAACTTCGGAACAATGAAATACCAATCACTCCCAACCCAATGCAAGGAGTGCGACTTTCTATTTGC
CTGCAACGGAGAATGTCCAAAGAACCGCTTCAGTCGGACAGCGGACGGCGAACCCGGTCTGAACTATCTGTGCAAAGGAT
ATTACCAATACTTTCAGCATGTAGCTCCCTATATGGATTTCATGAAAAAAGAATTAATGAATCAACAGGCTCCTGCCAAC
ATCATGAAAGCACTAAAAGACGGAAGTTTAAAAATAGAATATTAA

Upstream 100 bases:

>100_bases
TTATCAATATTTAAAACTTGTAAGACTCTTTTCTTTAATAATCCTTATAAACAGAGGTGGGAGATCATTTTTTTCATTTA
GTTTATCTAAATTTGCAGTC

Downstream 100 bases:

>100_bases
CATCATAATTTATAATTGTTATCATAAAGTAATGAACAGACTAAGACTTTATTTATTAGCGCTGACAGCGCTGCTGGTAT
GTACCGTAAAAGCGGACGAA

Product: anaerobic sulfatase-maturase

Products: NA

Alternate protein names: AnSME; Chondroitin sulfate/heparin utilization regulation protein; Ser-type sulfatase-activating enzyme

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKATTYAPFAKPLYVMVKPVGAVCNLACEYCYYLEKANLYKENPKHVMSDELLEKFIDEYINSQTMPQVLFTWHGGETLM
RPLSFYKKAMELQKKYARGRTIDNCIQTNGTLLTDEWCEFFRENNWLVGVSIDGPQEFHDEYRKNKMGKPSFVKVMQGIN
LLKKHGVEWNAMAVVNDFNAEYPLDFYNFFKEIDCHYIQFAPIVERIVSHQDGRHLASLAEGKEGALADFSVSPEQWGNF
LCTIFDEWVKEDVGKFFIQIFDSTLANWMGEQPGVCTMAKHCGHAGVMEFNGDVYSCDHFVFPEYKLGNIYSQTLVEMMH
SERQHNFGTMKYQSLPTQCKECDFLFACNGECPKNRFSRTADGEPGLNYLCKGYYQYFQHVAPYMDFMKKELMNQQAPAN
IMKALKDGSLKIEY

Sequences:

>Translated_414_residues
MKATTYAPFAKPLYVMVKPVGAVCNLACEYCYYLEKANLYKENPKHVMSDELLEKFIDEYINSQTMPQVLFTWHGGETLM
RPLSFYKKAMELQKKYARGRTIDNCIQTNGTLLTDEWCEFFRENNWLVGVSIDGPQEFHDEYRKNKMGKPSFVKVMQGIN
LLKKHGVEWNAMAVVNDFNAEYPLDFYNFFKEIDCHYIQFAPIVERIVSHQDGRHLASLAEGKEGALADFSVSPEQWGNF
LCTIFDEWVKEDVGKFFIQIFDSTLANWMGEQPGVCTMAKHCGHAGVMEFNGDVYSCDHFVFPEYKLGNIYSQTLVEMMH
SERQHNFGTMKYQSLPTQCKECDFLFACNGECPKNRFSRTADGEPGLNYLCKGYYQYFQHVAPYMDFMKKELMNQQAPAN
IMKALKDGSLKIEY
>Mature_414_residues
MKATTYAPFAKPLYVMVKPVGAVCNLACEYCYYLEKANLYKENPKHVMSDELLEKFIDEYINSQTMPQVLFTWHGGETLM
RPLSFYKKAMELQKKYARGRTIDNCIQTNGTLLTDEWCEFFRENNWLVGVSIDGPQEFHDEYRKNKMGKPSFVKVMQGIN
LLKKHGVEWNAMAVVNDFNAEYPLDFYNFFKEIDCHYIQFAPIVERIVSHQDGRHLASLAEGKEGALADFSVSPEQWGNF
LCTIFDEWVKEDVGKFFIQIFDSTLANWMGEQPGVCTMAKHCGHAGVMEFNGDVYSCDHFVFPEYKLGNIYSQTLVEMMH
SERQHNFGTMKYQSLPTQCKECDFLFACNGECPKNRFSRTADGEPGLNYLCKGYYQYFQHVAPYMDFMKKELMNQQAPAN
IMKALKDGSLKIEY

Specific function: Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Links the heparin and the chondroitin sulfate utilization pathways which contribute to the colonization of the intestinal tract. May catalyze the activation of chondro-6- sulfatase, i

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family

Homologues:

Organism=Escherichia coli, GI48994973, Length=397, Percent_Identity=45.8438287153652, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI87081923, Length=394, Percent_Identity=38.5786802030457, Blast_Score=298, Evalue=6e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANSME_BACTN (Q02550)

Other databases:

- EMBL:   L00678
- EMBL:   AE015928
- PIR:   A47014
- RefSeq:   NP_809151.1
- ProteinModelPortal:   Q02550
- GeneID:   1075612
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_0238
- NMPDR:   fig|226186.1.peg.238
- HOGENOM:   HBG484795
- OMA:   VTDWSVD
- PhylomeDB:   Q02550
- ProtClustDB:   PRK13745
- BioCyc:   BTHE226186:BT_0238-MONOMER
- InterPro:   IPR007197

Pfam domain/function: PF04055 Radical_SAM

EC number: NA

Molecular weight: Translated: 47949; Mature: 47949

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATTYAPFAKPLYVMVKPVGAVCNLACEYCYYLEKANLYKENPKHVMSDELLEKFIDEY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
INSQTMPQVLFTWHGGETLMRPLSFYKKAMELQKKYARGRTIDNCIQTNGTLLTDEWCEF
HCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECHHHHHH
FRENNWLVGVSIDGPQEFHDEYRKNKMGKPSFVKVMQGINLLKKHGVEWNAMAVVNDFNA
HHCCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
EYPLDFYNFFKEIDCHYIQFAPIVERIVSHQDGRHLASLAEGKEGALADFSVSPEQWGNF
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
LCTIFDEWVKEDVGKFFIQIFDSTLANWMGEQPGVCTMAKHCGHAGVMEFNGDVYSCDHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEECCCEEECCCE
VFPEYKLGNIYSQTLVEMMHSERQHNFGTMKYQSLPTQCKECDFLFACNGECPKNRFSRT
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCCEEEEECCCCCHHHCCCC
ADGEPGLNYLCKGYYQYFQHVAPYMDFMKKELMNQQAPANIMKALKDGSLKIEY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEECC
>Mature Secondary Structure
MKATTYAPFAKPLYVMVKPVGAVCNLACEYCYYLEKANLYKENPKHVMSDELLEKFIDEY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
INSQTMPQVLFTWHGGETLMRPLSFYKKAMELQKKYARGRTIDNCIQTNGTLLTDEWCEF
HCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECHHHHHH
FRENNWLVGVSIDGPQEFHDEYRKNKMGKPSFVKVMQGINLLKKHGVEWNAMAVVNDFNA
HHCCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
EYPLDFYNFFKEIDCHYIQFAPIVERIVSHQDGRHLASLAEGKEGALADFSVSPEQWGNF
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
LCTIFDEWVKEDVGKFFIQIFDSTLANWMGEQPGVCTMAKHCGHAGVMEFNGDVYSCDHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEECCCEEECCCE
VFPEYKLGNIYSQTLVEMMHSERQHNFGTMKYQSLPTQCKECDFLFACNGECPKNRFSRT
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCCEEEEECCCCCHHHCCCC
ADGEPGLNYLCKGYYQYFQHVAPYMDFMKKELMNQQAPANIMKALKDGSLKIEY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1429442; 12663928