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The map label for this gene is narL [H]

Identifier: 29345566

GI number: 29345566

Start: 161746

End: 162408

Strand: Reverse

Name: narL [H]

Synonym: BT_0156

Alternate gene names: 29345566

Gene position: 162408-161746 (Counterclockwise)

Preceding gene: 29345567

Following gene: 29345564

Centisome position: 2.59

GC content: 46.46

Gene sequence:

>663_bases
ATGAGGGAATATATCATCGCAGATAATCAGGATATCAGCAAGGCAGGAATGATGTTTCTGCTAAGCCGGCAAAAGGATGT
ATCCGTTCTTTTAGAAGCTGACAACAAGGCCGAACTGATTCAGCAGCTGCGCCTGTATCCGCAAGCAGTGGTTATTCTGG
ATTATACCTTATTCGATTTTGCCGGAGCGGACGAACTGATCGTCCTGCAGGAGCGGTTTAAAGAGGCCGACTGGATTCTG
TTCTCCGATGAGTTAAGTATCAATTTTCTCCGGCAGGTATTATTCAGCAGTATGGCTTTCGGAGTAGTGATGAAAGATAA
CTCAAAAGAGGAAATCATGTCCGCCCTGCAATGCGCTTCACGCAAACAACGGTATATCTGCAATCATGTCAGCAATCTGC
TGCTTTCGGGAACGGCTTCTTCCGCCGCATCCCCTGCAACGGTGGATGATCATCTGCTGACGCAGACAGAAAAGAATATC
CTCAAAGAAATTGCACTGGGGAAGACGACAAAAGAAATAGCGGCAGAAAAGAACCTCAGCTTTCATACAATCAACAGCCA
CCGAAAGAATATCTTCCGGAAGCTGGGAGTCAACAATGTGCACGAAGCTACCAAGTACGCGATGCGTGCAGGGATTGTGG
ATTTAGCGGAATACTATATTTGA

Upstream 100 bases:

>100_bases
GGACGTGCCTGGTAATCCGAACAGAAGAATATAAGAATAACTCCGCTACAAATCGCGCAAAATGCGTACATTTGTAGCGG
AGTTTTTTTAATTGATCATT

Downstream 100 bases:

>100_bases
CAGCCGGTTCAGTTCTGAAAGGGAACAGCCTATCGGGTTATCTCACCACTTCCGACACATATCCCCGCTTCTTCATCATA
AATCACCCCGAACTGACCGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MREYIIADNQDISKAGMMFLLSRQKDVSVLLEADNKAELIQQLRLYPQAVVILDYTLFDFAGADELIVLQERFKEADWIL
FSDELSINFLRQVLFSSMAFGVVMKDNSKEEIMSALQCASRKQRYICNHVSNLLLSGTASSAASPATVDDHLLTQTEKNI
LKEIALGKTTKEIAAEKNLSFHTINSHRKNIFRKLGVNNVHEATKYAMRAGIVDLAEYYI

Sequences:

>Translated_220_residues
MREYIIADNQDISKAGMMFLLSRQKDVSVLLEADNKAELIQQLRLYPQAVVILDYTLFDFAGADELIVLQERFKEADWIL
FSDELSINFLRQVLFSSMAFGVVMKDNSKEEIMSALQCASRKQRYICNHVSNLLLSGTASSAASPATVDDHLLTQTEKNI
LKEIALGKTTKEIAAEKNLSFHTINSHRKNIFRKLGVNNVHEATKYAMRAGIVDLAEYYI
>Mature_220_residues
MREYIIADNQDISKAGMMFLLSRQKDVSVLLEADNKAELIQQLRLYPQAVVILDYTLFDFAGADELIVLQERFKEADWIL
FSDELSINFLRQVLFSSMAFGVVMKDNSKEEIMSALQCASRKQRYICNHVSNLLLSGTASSAASPATVDDHLLTQTEKNI
LKEIALGKTTKEIAAEKNLSFHTINSHRKNIFRKLGVNNVHEATKYAMRAGIVDLAEYYI

Specific function: Probable member of the two-component regulatory system NarS/NarL [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=27.8048780487805, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1790102, Length=192, Percent_Identity=28.6458333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788222, Length=216, Percent_Identity=24.0740740740741, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24899; Mature: 24899

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREYIIADNQDISKAGMMFLLSRQKDVSVLLEADNKAELIQQLRLYPQAVVILDYTLFDF
CCCEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCHHHEEEHHHHHHH
AGADELIVLQERFKEADWILFSDELSINFLRQVLFSSMAFGVVMKDNSKEEIMSALQCAS
CCCCCEEHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
RKQRYICNHVSNLLLSGTASSAASPATVDDHLLTQTEKNILKEIALGKTTKEIAAEKNLS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
FHTINSHRKNIFRKLGVNNVHEATKYAMRAGIVDLAEYYI
EEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MREYIIADNQDISKAGMMFLLSRQKDVSVLLEADNKAELIQQLRLYPQAVVILDYTLFDF
CCCEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCHHHEEEHHHHHHH
AGADELIVLQERFKEADWILFSDELSINFLRQVLFSSMAFGVVMKDNSKEEIMSALQCAS
CCCCCEEHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHH
RKQRYICNHVSNLLLSGTASSAASPATVDDHLLTQTEKNILKEIALGKTTKEIAAEKNLS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
FHTINSHRKNIFRKLGVNNVHEATKYAMRAGIVDLAEYYI
EEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]