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The map label for this gene is nuoG [C]

Identifier: 29345534

GI number: 29345534

Start: 113201

End: 114967

Strand: Reverse

Name: nuoG [C]

Synonym: BT_0124

Alternate gene names: 29345534

Gene position: 114967-113201 (Counterclockwise)

Preceding gene: 29345535

Following gene: 29345533

Centisome position: 1.84

GC content: 54.44

Gene sequence:

>1767_bases
ATGGAAGAAAAACAAATTACCCTCCAGATAGACGGTCACTTTATCACCGTACCCGAAGGAAGCACGATCCTCGAAGCCGC
CTGCAAAATCGGCATCAACATACCTACGCTGTGTCACATCGACCTGAAAGGAACCTGTATCAAGAACAATCCCGCTTCCT
GCCGCATCTGTGTAGTCGAAGTGGCAGGACGCCGCAATCTGGCTCCCGCCTGCGCTACCCGTTGCACGGAAGGGATGGTG
GTGAAAACCAGTACCCTACGCGTGATGAACGCCCGGAAAGTGGTAGCCGAACTGATCCTGTCCGATCATCCCAACGACTG
TCTCACCTGTCCCAAATGCGGCAACTGTGAACTCCAGACACTGGCACTGCGTTTCAACATCCGTGAAATGCCGTTCAACG
GCGGCGAACTTTCTCCCCGCAAACGGGAAGTGACCTCCTCCATTGTGCGCAACATGGACAAGTGTATCTTCTGCCGCCGA
TGCGAAAGCGTCTGCAACGATGTACAGACAGTCGGCGCACTGGGAGCCATCCGCCGCGGATTCAACACAACGATAGCCCC
TGCCTTCGACAGAATGATGAAAGACAGCGAATGTACCTACTGCGGTCAATGCGTAGCCGTATGTCCGGTAGGCGCACTGA
CCGAACGGGATTACACCAACCGCCTTCTGGACGATTTGGCCGACCCCGATAAGATCGTAATTGTCCAGACTGCCCCCGCC
GTACGTGCCGCCCTGGGAGAAGAATTCGGCTTGCCTCCCGGCACACTGGTAACCGGAAAAATGGTTTACGCCCTCCGCGA
ACTGGGTTTCGACTATGTATTCGATACCGACTTTGCCGCCGACCTCACCATCATGGAAGAAGGTTCCGAAATCCTGAACC
GACTGACACGCTATCTGGACGGAGATAAATCCGTCCGGCTTCCGATCCTGACTTCCTGCTGCCCGGCTTGGGTAAACTTC
TTCGAGCACCACTTCCCGGATATGCTGGATATCCCTTCTACCGCCCGTTCTCCGCAACAGATGTTCGGCTCCATCGCCAA
GTCTTACTGGGCAGAGAAAATGGGAATTCCCCGCGAAAAGCTGGTAGTCGTCTCCATCATGCCCTGCCTAGCCAAGAAAT
ATGAATGTGACCGCGACGAGTTCAAAGTAAACGGTGTCCCCGACGTCGATTACTCCATCTCCACCCGCGAACTGGCACGC
CTGATAAAGCGAGCCAACATCGGCTTTACCCTCGTGCTGGACAGCCCGTTCGACAACCCTATGGGAGAATCGACCGGCGC
CGGTGTCATCTTCGGTACGACGGGTGGTGTCATGGAAGCCGCCCTGCGCTCCGTTTATGAAATCTACACCGGACAGCCGC
TGAAGAATGTCAACTTTGAACAGGTACGCGGACTGAGCGGTGTCCGGCGCGCCACCATCGACCTGAACGGATTTGAACTG
AAAGTAGGCATCGCACACGGACTAGGCAACGCAAGGCACTTACTAGAAGATATACGAAACGGACATAATGAATATCATGT
CATCGAAATCATGGCATGCCCCGGCGGCTGCATCGGAGGTGGCGGGCAACCGTTGCATCACGGCAACTCGGACGTTCTCT
ACGCCCGTGCCAACGCCCTTTACCGGGAAGATGCCAACAAACCTTTGCGCAAATCTCACGACAACCCGTATATTCAGAAA
CTGTATGAAGAATACCTCGGCAAACCGCTGGGTGAGAAATCGGAAATGCTCTTGCACACGCATTATTTCAACAAATCGAT
TGATTAA

Upstream 100 bases:

>100_bases
GCAAACCTCATGTCATCCACCCCGAGAAATGTATCAAGTGCGGCATGTGTATGGCACGCTGTAAATTCAAAGCTATTCTT
GTCTGTTAAAATCTACTGCT

Downstream 100 bases:

>100_bases
CTTTAAACAAGTACTATTATGTCAGATATCAAACTAGCCTGCGATGTGGTGGAACAAGTCAAGACGATTTGCGACAAGCA
CGGGAACAATGCGGGCGAAT

Product: NADH:ubiquinone oxidoreductase subunit

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MEEKQITLQIDGHFITVPEGSTILEAACKIGINIPTLCHIDLKGTCIKNNPASCRICVVEVAGRRNLAPACATRCTEGMV
VKTSTLRVMNARKVVAELILSDHPNDCLTCPKCGNCELQTLALRFNIREMPFNGGELSPRKREVTSSIVRNMDKCIFCRR
CESVCNDVQTVGALGAIRRGFNTTIAPAFDRMMKDSECTYCGQCVAVCPVGALTERDYTNRLLDDLADPDKIVIVQTAPA
VRAALGEEFGLPPGTLVTGKMVYALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLDGDKSVRLPILTSCCPAWVNF
FEHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECDRDEFKVNGVPDVDYSISTRELAR
LIKRANIGFTLVLDSPFDNPMGESTGAGVIFGTTGGVMEAALRSVYEIYTGQPLKNVNFEQVRGLSGVRRATIDLNGFEL
KVGIAHGLGNARHLLEDIRNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSDVLYARANALYREDANKPLRKSHDNPYIQK
LYEEYLGKPLGEKSEMLLHTHYFNKSID

Sequences:

>Translated_588_residues
MEEKQITLQIDGHFITVPEGSTILEAACKIGINIPTLCHIDLKGTCIKNNPASCRICVVEVAGRRNLAPACATRCTEGMV
VKTSTLRVMNARKVVAELILSDHPNDCLTCPKCGNCELQTLALRFNIREMPFNGGELSPRKREVTSSIVRNMDKCIFCRR
CESVCNDVQTVGALGAIRRGFNTTIAPAFDRMMKDSECTYCGQCVAVCPVGALTERDYTNRLLDDLADPDKIVIVQTAPA
VRAALGEEFGLPPGTLVTGKMVYALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLDGDKSVRLPILTSCCPAWVNF
FEHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECDRDEFKVNGVPDVDYSISTRELAR
LIKRANIGFTLVLDSPFDNPMGESTGAGVIFGTTGGVMEAALRSVYEIYTGQPLKNVNFEQVRGLSGVRRATIDLNGFEL
KVGIAHGLGNARHLLEDIRNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSDVLYARANALYREDANKPLRKSHDNPYIQK
LYEEYLGKPLGEKSEMLLHTHYFNKSID
>Mature_588_residues
MEEKQITLQIDGHFITVPEGSTILEAACKIGINIPTLCHIDLKGTCIKNNPASCRICVVEVAGRRNLAPACATRCTEGMV
VKTSTLRVMNARKVVAELILSDHPNDCLTCPKCGNCELQTLALRFNIREMPFNGGELSPRKREVTSSIVRNMDKCIFCRR
CESVCNDVQTVGALGAIRRGFNTTIAPAFDRMMKDSECTYCGQCVAVCPVGALTERDYTNRLLDDLADPDKIVIVQTAPA
VRAALGEEFGLPPGTLVTGKMVYALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLDGDKSVRLPILTSCCPAWVNF
FEHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECDRDEFKVNGVPDVDYSISTRELAR
LIKRANIGFTLVLDSPFDNPMGESTGAGVIFGTTGGVMEAALRSVYEIYTGQPLKNVNFEQVRGLSGVRRATIDLNGFEL
KVGIAHGLGNARHLLEDIRNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSDVLYARANALYREDANKPLRKSHDNPYIQK
LYEEYLGKPLGEKSEMLLHTHYFNKSID

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=418, Percent_Identity=29.4258373205742, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI6912524, Length=407, Percent_Identity=26.5356265356265, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI134284357, Length=366, Percent_Identity=27.3224043715847, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI84452151, Length=374, Percent_Identity=27.807486631016, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI14165461, Length=453, Percent_Identity=24.0618101545254, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI33519475, Length=213, Percent_Identity=29.5774647887324, Blast_Score=109, Evalue=9e-24,
Organism=Escherichia coli, GI145693161, Length=220, Percent_Identity=25, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71995015, Length=409, Percent_Identity=26.6503667481663, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17565758, Length=219, Percent_Identity=32.4200913242009, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566231, Length=219, Percent_Identity=32.4200913242009, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193209088, Length=218, Percent_Identity=31.651376146789, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324089, Length=401, Percent_Identity=23.6907730673317, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI116007464, Length=332, Percent_Identity=32.2289156626506, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI116007468, Length=332, Percent_Identity=32.2289156626506, Blast_Score=145, Evalue=9e-35,
Organism=Drosophila melanogaster, GI116007470, Length=330, Percent_Identity=32.4242424242424, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI116007466, Length=330, Percent_Identity=32.4242424242424, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI116007462, Length=286, Percent_Identity=32.5174825174825, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24640559, Length=220, Percent_Identity=29.0909090909091, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24640557, Length=220, Percent_Identity=29.0909090909091, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 64977; Mature: 64977

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKQITLQIDGHFITVPEGSTILEAACKIGINIPTLCHIDLKGTCIKNNPASCRICVVE
CCCCEEEEEECCEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCEEEEEEE
VAGRRNLAPACATRCTEGMVVKTSTLRVMNARKVVAELILSDHPNDCLTCPKCGNCELQT
ECCCCCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
LALRFNIREMPFNGGELSPRKREVTSSIVRNMDKCIFCRRCESVCNDVQTVGALGAIRRG
EEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FNTTIAPAFDRMMKDSECTYCGQCVAVCPVGALTERDYTNRLLDDLADPDKIVIVQTAPA
CCCCHHHHHHHHHCCCCCCHHCCHHHHCCCCHHHCCHHHHHHHHHHCCCCCEEEEECCHH
VRAALGEEFGLPPGTLVTGKMVYALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLD
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEEEHHHHHHHHHHHHHHHC
GDKSVRLPILTSCCPAWVNFFEHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREK
CCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
LVVVSIMPCLAKKYECDRDEFKVNGVPDVDYSISTRELARLIKRANIGFTLVLDSPFDNP
EEEEHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
MGESTGAGVIFGTTGGVMEAALRSVYEIYTGQPLKNVNFEQVRGLSGVRRATIDLNGFEL
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEECCCEEE
KVGIAHGLGNARHLLEDIRNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSDVLYARANAL
EEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHH
YREDANKPLRKSHDNPYIQKLYEEYLGKPLGEKSEMLLHTHYFNKSID
HHHCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCC
>Mature Secondary Structure
MEEKQITLQIDGHFITVPEGSTILEAACKIGINIPTLCHIDLKGTCIKNNPASCRICVVE
CCCCEEEEEECCEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCEEEEEEE
VAGRRNLAPACATRCTEGMVVKTSTLRVMNARKVVAELILSDHPNDCLTCPKCGNCELQT
ECCCCCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
LALRFNIREMPFNGGELSPRKREVTSSIVRNMDKCIFCRRCESVCNDVQTVGALGAIRRG
EEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FNTTIAPAFDRMMKDSECTYCGQCVAVCPVGALTERDYTNRLLDDLADPDKIVIVQTAPA
CCCCHHHHHHHHHCCCCCCHHCCHHHHCCCCHHHCCHHHHHHHHHHCCCCCEEEEECCHH
VRAALGEEFGLPPGTLVTGKMVYALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLD
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEEEHHHHHHHHHHHHHHHC
GDKSVRLPILTSCCPAWVNFFEHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREK
CCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
LVVVSIMPCLAKKYECDRDEFKVNGVPDVDYSISTRELARLIKRANIGFTLVLDSPFDNP
EEEEHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
MGESTGAGVIFGTTGGVMEAALRSVYEIYTGQPLKNVNFEQVRGLSGVRRATIDLNGFEL
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEECCCEEE
KVGIAHGLGNARHLLEDIRNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSDVLYARANAL
EEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHH
YREDANKPLRKSHDNPYIQKLYEEYLGKPLGEKSEMLLHTHYFNKSID
HHHCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]