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The map label for this gene is ahpC [C]

Identifier: 29142849

GI number: 29142849

Start: 2530220

End: 2530822

Strand: Direct

Name: ahpC [C]

Synonym: t2461

Alternate gene names: 29142849

Gene position: 2530220-2530822 (Clockwise)

Preceding gene: 29142848

Following gene: 29142856

Centisome position: 52.8

GC content: 53.4

Gene sequence:

>603_bases
ATGGTACTGGTTACTCGTCAGGCCCCGGATTTCACCGCTGCGGCGGTACTGGGTAGCGGTGAGATTGTTGATAAATTCAA
CTTCAAACAGCACACCAATGGTAAAACGACCGTTCTGTTCTTCTGGCCGATGGACTTCACTTTTGTTTGCCCGTCTGAGC
TGATCGCCTTCGATAAACGTTATGAAGAATTCCAGAAGCGCGGCGTTGAAGTGGTCGGCGTTTCTTTCGACTCTGAGTTC
GTCCACAACGCATGGCGTAACACCCCTGTCGATAAAGGCGGCATTGGCCCGGTGAAATACGCAATGGTCGCTGACGTGAA
GCGTGAAATTCAGAAAGCTTACGGTATCGAACATCCGGACGAAGGCGTTGCGCTGCGCGGCTCTTTCCTGATTGACGCAA
ACGGTATTGTTCGCCACCAGGTCGTAAACGATCTGCCGCTGGGTCGTAACATCGACGAAATGCTGCGTATGGTCGACGCG
CTGCAGTTCCACGAAGAGCACGGCGATGTCTGCCCGGCGCAGTGGGAAAAAGGCAAAGAAGGCATGAACGCCTCTCCGGA
CGGCGTGGCTAAATACCTGGCTGAGAATATTTCCAGCCTGTAA

Upstream 100 bases:

>100_bases
CTGTCTCATTGATTGTCAAGACCGCATTGTTTTGTCGCTTCGCCCTCCCTATACTGCCCGCGTTGCGTTCTAAAACCCTT
AATATTGCAGGAGAATTATT

Downstream 100 bases:

>100_bases
GTCAGTGCATTGATAAAAGGCTCGCGAATGCGAGCCTTTTTTATGCGTGAGGTATTATGAACCACCTCGCCTCAACGATT
CATCCATACCGTCGCGGAAA

Product: peroxidase

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MVLVTRQAPDFTAAAVLGSGEIVDKFNFKQHTNGKTTVLFFWPMDFTFVCPSELIAFDKRYEEFQKRGVEVVGVSFDSEF
VHNAWRNTPVDKGGIGPVKYAMVADVKREIQKAYGIEHPDEGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDA
LQFHEEHGDVCPAQWEKGKEGMNASPDGVAKYLAENISSL

Sequences:

>Translated_200_residues
MVLVTRQAPDFTAAAVLGSGEIVDKFNFKQHTNGKTTVLFFWPMDFTFVCPSELIAFDKRYEEFQKRGVEVVGVSFDSEF
VHNAWRNTPVDKGGIGPVKYAMVADVKREIQKAYGIEHPDEGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDA
LQFHEEHGDVCPAQWEKGKEGMNASPDGVAKYLAENISSL
>Mature_200_residues
MVLVTRQAPDFTAAAVLGSGEIVDKFNFKQHTNGKTTVLFFWPMDFTFVCPSELIAFDKRYEEFQKRGVEVVGVSFDSEF
VHNAWRNTPVDKGGIGPVKYAMVADVKREIQKAYGIEHPDEGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDA
LQFHEEHGDVCPAQWEKGKEGMNASPDGVAKYLAENISSL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=47.9381443298969, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI4505591, Length=189, Percent_Identity=46.5608465608466, Blast_Score=190, Evalue=7e-49,
Organism=Homo sapiens, GI32455266, Length=189, Percent_Identity=46.5608465608466, Blast_Score=190, Evalue=7e-49,
Organism=Homo sapiens, GI32455264, Length=189, Percent_Identity=46.5608465608466, Blast_Score=190, Evalue=7e-49,
Organism=Homo sapiens, GI5453549, Length=190, Percent_Identity=45.2631578947368, Blast_Score=180, Evalue=8e-46,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=45.8333333333333, Blast_Score=180, Evalue=8e-46,
Organism=Homo sapiens, GI32483377, Length=191, Percent_Identity=45.5497382198953, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=53.0120481927711, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI4758638, Length=195, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1786822, Length=164, Percent_Identity=39.0243902439024, Blast_Score=126, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17554494, Length=170, Percent_Identity=45.2941176470588, Blast_Score=166, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI193204376, Length=181, Percent_Identity=45.3038674033149, Blast_Score=166, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI32565831, Length=181, Percent_Identity=45.3038674033149, Blast_Score=166, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI25153706, Length=179, Percent_Identity=30.1675977653631, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323613, Length=190, Percent_Identity=40, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6320661, Length=175, Percent_Identity=41.1428571428571, Blast_Score=151, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6319407, Length=181, Percent_Identity=30.3867403314917, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=46.3917525773196, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=46.3917525773196, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17738015, Length=186, Percent_Identity=44.6236559139785, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI17157991, Length=194, Percent_Identity=41.2371134020619, Blast_Score=166, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24641739, Length=194, Percent_Identity=41.2371134020619, Blast_Score=166, Evalue=7e-42,
Organism=Drosophila melanogaster, GI21357347, Length=198, Percent_Identity=41.9191919191919, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24581278, Length=182, Percent_Identity=32.4175824175824, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17975518, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24652436, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24652434, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22318; Mature: 22318

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLVTRQAPDFTAAAVLGSGEIVDKFNFKQHTNGKTTVLFFWPMDFTFVCPSELIAFDKR
CEEEECCCCCCHHHEEECCCCEEECCCCCCCCCCCEEEEEEECCCEEEECHHHHHHHHHH
YEEFQKRGVEVVGVSFDSEFVHNAWRNTPVDKGGIGPVKYAMVADVKREIQKAYGIEHPD
HHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
EGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDALQFHEEHGDVCPAQWEKGKE
CCEEEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
GMNASPDGVAKYLAENISSL
CCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVLVTRQAPDFTAAAVLGSGEIVDKFNFKQHTNGKTTVLFFWPMDFTFVCPSELIAFDKR
CEEEECCCCCCHHHEEECCCCEEECCCCCCCCCCCEEEEEEECCCEEEECHHHHHHHHHH
YEEFQKRGVEVVGVSFDSEFVHNAWRNTPVDKGGIGPVKYAMVADVKREIQKAYGIEHPD
HHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
EGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDALQFHEEHGDVCPAQWEKGKE
CCEEEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
GMNASPDGVAKYLAENISSL
CCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]