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The map label for this gene is uxuR [H]

Identifier: 29141909

GI number: 29141909

Start: 1503380

End: 1504171

Strand: Direct

Name: uxuR [H]

Synonym: t1460

Alternate gene names: 29141909

Gene position: 1503380-1504171 (Clockwise)

Preceding gene: 29141908

Following gene: 29141914

Centisome position: 31.37

GC content: 46.72

Gene sequence:

>792_bases
ATGGAGACTACCGGCGGTTGCTTCTCTTTATCATGCACGGTAATTAATTATCACGATCACCAGCGCCAGGATGGTATGCT
AAATCCATTCAAAATCCCCTGGATATGGATTGGAGGGCGCATGGTTATACCTGAGGTCAGGCAGGAGAGGCTCTATCAGA
AGATAGCCAACCTCATCATTAAGCTGATCAATGATAATATTTTTCCACCGGGAACTTTTTTACCGCCAGAACGCGAACTG
GCAAAACAGCTTGGCGTGAGCCGCGCCTCCTTGCGAGAAGCCCTTATTGTACTGGAGATCTCCGGATGGATCGTGATTCA
GTCCGGTAATGGGGTTATCGTTTCAGATAAAAAACACCTTGCCAGTGACTATACCATCGAAGAAATTCTCTCTACTCGCG
AGCTGGTCGATAGCCATTGTGCGCGCTTAGCCGCACAAAACGATAACGTTGACGTCATCAACCAAATAGAGGCGATTTAT
CATCGTATGGATCAAGCCATTAACGATAATAACGTCCACGGCTTTTACTCGCTGGATAAAGAGTTTCACCTTGCGATCTC
TGAGGCCAGCCGTAACCGGGTGTTGTTTGATATGTCCCGTATGTTATGGGAACAACGGATTAATATCCCTTACGCCGGGC
TTGATGAACAGTCTGGAGACAGAAATGTTTTACTTAATCTCAACAAACAACATAAAGCGATAGTGGATGCGATGCGCCAG
TCTGATGCTGACAGCGCTTATGAGGGATCGCTGGAACATTTACGCTATGTGAGAAAGATTGTCGGCGGCTAA

Upstream 100 bases:

>100_bases
TCAGTTTAAGAACGCGACTGCGCCCGTGTTCGAGAAAATCAACGTCAAAGGATAAACCGCTCGTCTCTGTTTAGTTTCCC
CGGTAGTCTCGGCGAAGGTA

Downstream 100 bases:

>100_bases
GTTTGTCGGTAAATAACACCGCATGGCGGATATGCCATGCGGTAGAACTCGCCGTAAATCAATGGAAAACAGCATTAATC
TTTAAGTAACGCTCCGGATA

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
METTGGCFSLSCTVINYHDHQRQDGMLNPFKIPWIWIGGRMVIPEVRQERLYQKIANLIIKLINDNIFPPGTFLPPEREL
AKQLGVSRASLREALIVLEISGWIVIQSGNGVIVSDKKHLASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIY
HRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSRMLWEQRINIPYAGLDEQSGDRNVLLNLNKQHKAIVDAMRQ
SDADSAYEGSLEHLRYVRKIVGG

Sequences:

>Translated_263_residues
METTGGCFSLSCTVINYHDHQRQDGMLNPFKIPWIWIGGRMVIPEVRQERLYQKIANLIIKLINDNIFPPGTFLPPEREL
AKQLGVSRASLREALIVLEISGWIVIQSGNGVIVSDKKHLASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIY
HRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSRMLWEQRINIPYAGLDEQSGDRNVLLNLNKQHKAIVDAMRQ
SDADSAYEGSLEHLRYVRKIVGG
>Mature_263_residues
METTGGCFSLSCTVINYHDHQRQDGMLNPFKIPWIWIGGRMVIPEVRQERLYQKIANLIIKLINDNIFPPGTFLPPEREL
AKQLGVSRASLREALIVLEISGWIVIQSGNGVIVSDKKHLASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIY
HRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSRMLWEQRINIPYAGLDEQSGDRNVLLNLNKQHKAIVDAMRQ
SDADSAYEGSLEHLRYVRKIVGG

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=226, Percent_Identity=30.9734513274336, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082208, Length=230, Percent_Identity=29.1304347826087, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790032, Length=224, Percent_Identity=30.8035714285714, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786303, Length=243, Percent_Identity=27.9835390946502, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789353, Length=219, Percent_Identity=31.0502283105023, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29940; Mature: 29940

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTGGCFSLSCTVINYHDHQRQDGMLNPFKIPWIWIGGRMVIPEVRQERLYQKIANLII
CCCCCCEEEEEEEEEECCCCCCCCCCCCCEECCEEEECCEEECHHHHHHHHHHHHHHHHH
KLINDNIFPPGTFLPPERELAKQLGVSRASLREALIVLEISGWIVIQSGNGVIVSDKKHL
HHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHEEEEEEECCEEEEECCCEEEEECHHHH
ASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIYHRMDQAINDNNVHGFYSLDK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
EFHLAISEASRNRVLFDMSRMLWEQRINIPYAGLDEQSGDRNVLLNLNKQHKAIVDAMRQ
EEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
SDADSAYEGSLEHLRYVRKIVGG
CCCCCHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure
METTGGCFSLSCTVINYHDHQRQDGMLNPFKIPWIWIGGRMVIPEVRQERLYQKIANLII
CCCCCCEEEEEEEEEECCCCCCCCCCCCCEECCEEEECCEEECHHHHHHHHHHHHHHHHH
KLINDNIFPPGTFLPPERELAKQLGVSRASLREALIVLEISGWIVIQSGNGVIVSDKKHL
HHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHEEEEEEECCEEEEECCCEEEEECHHHH
ASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIYHRMDQAINDNNVHGFYSLDK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
EFHLAISEASRNRVLFDMSRMLWEQRINIPYAGLDEQSGDRNVLLNLNKQHKAIVDAMRQ
EEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
SDADSAYEGSLEHLRYVRKIVGG
CCCCCHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]