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The map label for this gene is dcp [H]

Identifier: 29141884

GI number: 29141884

Start: 1477964

End: 1480006

Strand: Direct

Name: dcp [H]

Synonym: t1433

Alternate gene names: 29141884

Gene position: 1477964-1480006 (Clockwise)

Preceding gene: 29141880

Following gene: 29141885

Centisome position: 30.84

GC content: 53.55

Gene sequence:

>2043_bases
ATGTCGACGAATCCTTTGTTAGACCAGAGTATGTTGCCTTATCAGGCACCGCGTTTTGATCGGATCAAAGATTGCCATTA
TCGTCCTGCTTTTGATGAGGGCGTGCGGCAAAAACGCGTGGAAATCGAGGCCATCGTCAATCATCCGGCGGCCCCTGATT
TTACGAATACGCTTCTGGCGCTGGAGCAAAGCGGGGCGCTTCTGTCACGCGTCACCAGCGTTTTTTTCGCGATGACGGCT
GCGCACACTAACGATGAACTCCAGCGGTTGGATGAGGCCTTTTCTGCCGAGCTGGCGGCGCTCTCCAACGATATTTATCT
GAATAGCGCGTTATTCGCTCGCGTGGATGCCGTCTGGCAACAGCGTCACTCACTGGGGCTGGATGATGAGTCGCTACGGT
TGGTCGATGTTATCCATCAGCGTTTTGTGTTGGCAGGCGCGCAGCTTGCCGAAGAGGATAAAGCGCGACTGAAAGTATTG
AATACTGAATCCGCGACCTTAATGAGTCAGTTTAATCAGCGTCTGCTGGCGGCAAGTAAAGCGGGCGGGCTGGCGGTAGA
TGACGCGCATTGTCTGGAAGGATTAAGCCCGGAAGAAATGACCGTCGCTGCTGAAGCGGCGCGTGAAAAAGGCCTGGAGG
AGCGCTGGTTCATTCCGCTCCTTAATACGACGCAACAGCCTGCGCTTGCTACGCTGCGCGATCGCCAGACTCGCGAAAAT
TTATTCGCAGCGTCATGGACTCGGGCGGAAAAAGGAGATGCCCACGATACCCGCGCTATCGTTCAGCGTCTGGTAGAGAT
TCGCCGCTGTCAGGCAAAACTGCTGGGTTTCCCCAATTATGCCGCATGGAAAATGGCCGATCAGATGGCGAAAACGCCGC
AAGCCGCACTGAGCTTTATGCGTGGCATTGTGCCGCCAGCGCGTCAGCGGGTACTCAATGAACAGGCGGAAATTCAGAAC
GTCATTGATGGTGAGCAGGGCGGCTACACCGTTCAGGCCTGGGACTGGATGTTCTATGCCGAACAGGTACGGCGGGAAAA
ATATGCGTTAGATGAAGCGCAACTGAAGCCCTATTTTGCCTTAAATACGGTGTTGCAAGAGGGGGTTTTCTGGACCGCCA
ACCAGCTATTCGGCATCACCTTCGTCGAGCGTTTTGACATTCCGGTGTACCACCCTGATGTTCGGGTGTGGGAGATTTTC
GACTCCGATGGTGTCGGCATGGCGTTATTTTATGGCGACTTCTTCGCGCGGGACTCGAAAAGCGGCGGCGCGTGGATGGG
GAATTTTGTCGAGCAATCCACACTCAATGAAACCCGGCCCGTTATATACAATGTATGTAACTATCAGAAACCGGTTGATG
GGCAGCCTGCATTGCTGCTTTGGGACGACGTTATTACGCTCTTCCATGAGTTTGGTCATACGTTACATGGTTTGTTTGCC
GTTCAGCGCTATGCCACGCTTTCAGGTACCAATACGCCCCGCGACTTTGTCGAGTTTCCCTCCCAGATTAATGAGCATTG
GGCGAGCCATCCACGTGTGTTCGAACGCTACGCGCGTCATGTCGACAGCGGTGAAAAAATGCCTGCTGATTTACAGGAAA
GAATGCGCAAGGCGAGTTTATTTAATAAAGGTTACGATATGACTGAATTGTTCGGCGCCGCATTGCTGGATATGCGCTGG
CATATGCTGGAGGAGAGCGTAGCAGAGCAGTCTGTCGCTGAGTTCGAGCAGCAGGCGCTGGCCGCCGAGCATCTTGATTT
ACCGGCAGTGCCGCCCCGCTATCGCAGCAGTTATTTTGCCCATATCTTCGGCGGCGGCTACGCAGCGGGATACTACGCCT
ACCTGTGGACGCAAATGTTAGCGGATGACGGTTATCAATGGTTTGTAGAGCAGGGCGGCCTGACGCGTGAAAACGGGCAG
CGTTTTCGTGATGCTATCCTTTCCCGGGGGAATAGTACTGATTTAGAAACGCTTTATTCAGCCTGGCGTGGACATGAACC
GCATATTGACACCATATTGCAATATCGTGGGCTCGATCACTAA

Upstream 100 bases:

>100_bases
AGCACGCGGCGTTTATGAAAGGGTAATCCTGGTTAACACGGTTGCGGTCAGCATAGGGGGAAGCTTACTCTTATGATCAA
CCTATTTTCAGGAGTGAAAA

Downstream 100 bases:

>100_bases
GCTGATACGGTTGTTCGGCACTGTCGAACAACCGCCTGAAAATGAATCCTGCACTTCTGATGACAGCCAGTTAAATTTAT
GGGGTTAAGTTGTCTGAATA

Product: dipeptidyl carboxypeptidase II

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 680; Mature: 679

Protein sequence:

>680_residues
MSTNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLALEQSGALLSRVTSVFFAMTA
AHTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQQRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVL
NTESATLMSQFNQRLLAASKAGGLAVDDAHCLEGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTREN
LFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFMRGIVPPARQRVLNEQAEIQN
VIDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFALNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIF
DSDGVGMALFYGDFFARDSKSGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFA
VQRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELFGAALLDMRW
HMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQ
RFRDAILSRGNSTDLETLYSAWRGHEPHIDTILQYRGLDH

Sequences:

>Translated_680_residues
MSTNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLALEQSGALLSRVTSVFFAMTA
AHTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQQRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVL
NTESATLMSQFNQRLLAASKAGGLAVDDAHCLEGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTREN
LFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFMRGIVPPARQRVLNEQAEIQN
VIDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFALNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIF
DSDGVGMALFYGDFFARDSKSGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFA
VQRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELFGAALLDMRW
HMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQ
RFRDAILSRGNSTDLETLYSAWRGHEPHIDTILQYRGLDH
>Mature_679_residues
STNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLALEQSGALLSRVTSVFFAMTAA
HTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQQRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVLN
TESATLMSQFNQRLLAASKAGGLAVDDAHCLEGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTRENL
FAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFMRGIVPPARQRVLNEQAEIQNV
IDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFALNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIFD
SDGVGMALFYGDFFARDSKSGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFAV
QRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELFGAALLDMRWH
MLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQR
FRDAILSRGNSTDLETLYSAWRGHEPHIDTILQYRGLDH

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=603, Percent_Identity=26.865671641791, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI14149738, Length=554, Percent_Identity=27.6173285198556, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI156105687, Length=650, Percent_Identity=22.6153846153846, Blast_Score=143, Evalue=4e-34,
Organism=Escherichia coli, GI1787819, Length=678, Percent_Identity=78.4660766961652, Blast_Score=1083, Evalue=0.0,
Organism=Escherichia coli, GI1789913, Length=685, Percent_Identity=32.1167883211679, Blast_Score=334, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6319793, Length=660, Percent_Identity=24.6969696969697, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6322715, Length=421, Percent_Identity=23.0403800475059, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI21356111, Length=571, Percent_Identity=24.1681260945709, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI20129717, Length=397, Percent_Identity=25.9445843828715, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 77337; Mature: 77206

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLA
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LEQSGALLSRVTSVFFAMTAAHTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQ
HHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
QRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVLNTESATLMSQFNQRLLAASK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHC
AGGLAVDDAHCLEGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTREN
CCCCEECCHHHHCCCCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHHHH
LFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFM
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHH
RGIVPPARQRVLNEQAEIQNVIDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFA
HHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHCCHHHH
LNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIFDSDGVGMALFYGDFFARDSK
HHHHHHCCCEEEHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCEEEEEHHHHHHCCCC
SGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFA
CCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VQRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASL
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FNKGYDMTELFGAALLDMRWHMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEE
HIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQRFRDAILSRGNSTDLETLYS
HHHCCCHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
AWRGHEPHIDTILQYRGLDH
HHCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
STNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLA
CCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LEQSGALLSRVTSVFFAMTAAHTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQ
HHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
QRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVLNTESATLMSQFNQRLLAASK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHC
AGGLAVDDAHCLEGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTREN
CCCCEECCHHHHCCCCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHHHH
LFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFM
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHH
RGIVPPARQRVLNEQAEIQNVIDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFA
HHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHCCHHHH
LNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIFDSDGVGMALFYGDFFARDSK
HHHHHHCCCEEEHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCEEEEEHHHHHHCCCC
SGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFA
CCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VQRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASL
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FNKGYDMTELFGAALLDMRWHMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEE
HIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQRFRDAILSRGNSTDLETLYS
HHHCCCHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
AWRGHEPHIDTILQYRGLDH
HHCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537804; 11677609 [H]