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The map label for this gene is isaA [H]

Identifier: 28379443

GI number: 28379443

Start: 2683135

End: 2683797

Strand: Direct

Name: isaA [H]

Synonym: lp_3015

Alternate gene names: 28379443

Gene position: 2683135-2683797 (Clockwise)

Preceding gene: 28379442

Following gene: 28379445

Centisome position: 81.1

GC content: 49.62

Gene sequence:

>663_bases
TTGAAAAAATTATTAACCACAATCTTAACAACATCCGCTGCAACGGTTGGCCTACTATTGGCCGGAACTGTTTCTGCACA
CGCCGACGCAACTTACACCGTTAAGAAGGGTGACTGTGTCTGGGCAATTTCACAAGAATATAAGACGACGATCGAATCAA
TCGAAACAGCCAACAACATTCACGGCCATTTAATTTTACCAGGCCAACAATTACGGATTCCAGGGGTGAACGCCCAGGAC
CTTACTAGTCAAGCACCAGCGACACCGGTCGTTTCAGCGCCAGTTCAGCAGGCACCGGTCACCACACCAACCCAGCCAGC
TGAAACACAGGCCGCAACTACGACTCAAACAACACCAGCACAAACTAACGAGACGGTTGCTTCGGCACCAGCAACTACCC
CGGCAACTGAAAGCTATTCGGGTGATAACCTACAAAGTTACGTGCTCGGTCAAATGCAAGCACGGACTGGTGTTGACGCC
GGAACTTGGAATCACATCATCAATCGTGAATCTAACTGGCAGCCACACGTCGTTAACGGCGCAAGCGGTGCATACGGTTT
ATTCCAAAACATCCATATTAGTGGTGGTTCCGTTCAACAACAAATCGACGCCGCAGTTAACTTGTACCACGCACAAGGCA
TGCAAGCCTGGGCCCTCTATTAA

Upstream 100 bases:

>100_bases
TTAGCGACACATGCGAGTAATAAGTCGCCGCTATACTAATTTTTGTTGATCAACAATTGTACGACACGCTGATTGCTTAC
AAAAAATGGGAGAGTATAAC

Downstream 100 bases:

>100_bases
AAAGACACTAAAAAAGGCTGGAATTTTCCAGCCTTTTTTGCCGTTCAACGATTGTTAACAACGCTTCAACTAACCACGAT
TAACGTGACTTGTGCCACTC

Product: extracellular protein

Products: NA

Alternate protein names: Immunodominant staphylococcal antigen A [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKKLLTTILTTSAATVGLLLAGTVSAHADATYTVKKGDCVWAISQEYKTTIESIETANNIHGHLILPGQQLRIPGVNAQD
LTSQAPATPVVSAPVQQAPVTTPTQPAETQAATTTQTTPAQTNETVASAPATTPATESYSGDNLQSYVLGQMQARTGVDA
GTWNHIINRESNWQPHVVNGASGAYGLFQNIHISGGSVQQQIDAAVNLYHAQGMQAWALY

Sequences:

>Translated_220_residues
MKKLLTTILTTSAATVGLLLAGTVSAHADATYTVKKGDCVWAISQEYKTTIESIETANNIHGHLILPGQQLRIPGVNAQD
LTSQAPATPVVSAPVQQAPVTTPTQPAETQAATTTQTTPAQTNETVASAPATTPATESYSGDNLQSYVLGQMQARTGVDA
GTWNHIINRESNWQPHVVNGASGAYGLFQNIHISGGSVQQQIDAAVNLYHAQGMQAWALY
>Mature_220_residues
MKKLLTTILTTSAATVGLLLAGTVSAHADATYTVKKGDCVWAISQEYKTTIESIETANNIHGHLILPGQQLRIPGVNAQD
LTSQAPATPVVSAPVQQAPVTTPTQPAETQAATTTQTTPAQTNETVASAPATTPATESYSGDNLQSYVLGQMQARTGVDA
GTWNHIINRESNWQPHVVNGASGAYGLFQNIHISGGSVQQQIDAAVNLYHAQGMQAWALY

Specific function: Is able to cleave peptidoglycan [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase family. IsaA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010618 [H]

Pfam domain/function: PF06737 Transglycosylas [H]

EC number: NA

Molecular weight: Translated: 23162; Mature: 23162

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLTTILTTSAATVGLLLAGTVSAHADATYTVKKGDCVWAISQEYKTTIESIETANNI
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECHHHHHHHHHHHHHCCC
HGHLILPGQQLRIPGVNAQDLTSQAPATPVVSAPVQQAPVTTPTQPAETQAATTTQTTPA
CEEEEECCCEEECCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
QTNETVASAPATTPATESYSGDNLQSYVLGQMQARTGVDAGTWNHIINRESNWQPHVVNG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCEEECC
ASGAYGLFQNIHISGGSVQQQIDAAVNLYHAQGMQAWALY
CCCCCHHHEEEEECCCHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MKKLLTTILTTSAATVGLLLAGTVSAHADATYTVKKGDCVWAISQEYKTTIESIETANNI
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECHHHHHHHHHHHHHCCC
HGHLILPGQQLRIPGVNAQDLTSQAPATPVVSAPVQQAPVTTPTQPAETQAATTTQTTPA
CEEEEECCCEEECCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
QTNETVASAPATTPATESYSGDNLQSYVLGQMQARTGVDAGTWNHIINRESNWQPHVVNG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCEEECC
ASGAYGLFQNIHISGGSVQQQIDAAVNLYHAQGMQAWALY
CCCCCHHHEEEEECCCHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA