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The map label for this gene is isaA [H]

Identifier: 28379442

GI number: 28379442

Start: 2682080

End: 2682694

Strand: Direct

Name: isaA [H]

Synonym: lp_3014

Alternate gene names: 28379442

Gene position: 2682080-2682694 (Clockwise)

Preceding gene: 28379441

Following gene: 28379443

Centisome position: 81.07

GC content: 44.23

Gene sequence:

>615_bases
TTGAAAAAACTTGTAAGTACAATCGTAACTACCTCAGCTGCAGCCGCTGGTTTATTATTCGCCGGTGTCCTCAATGCTAA
CGCCGACTCAACTTACACCGTTAAGAGCGGTGATTCCGTTTGGGCCATCGCACAAAAATTCAACACAACTATCAATCATG
TTGAAACGACTAATAACATCAAGGGTCACTACATCTTACCTGGTCAAAAACTATCTATTAAGACGAGTTCAACCAGTTCT
GATAACAACACCTCATCAACGACTTCAAACACAACGAGTTCAAGTGCTTCAACGACTAGTTCTAGTTCAACTAGCAACAC
AACCGCGACGACCACTTCAACGAGTTCAACTGACTCCACGACTTCAAGCTACACTGGTAGCAATTTGAAGAGTTACGTTT
TAAGTCAGATGCAATCACGGACTGGTGTCTCAGCTTCGACTTGGAACACGATTATTACGCGTGAATCCAACTGGCAACCA
TACGTCCGCAACAGTTCTAGTGGTGCCTACGGGTTATTCCAGAACATGCACATCAGCAGTGGTTCTGTTGAAGAACAAGT
TAACGCTGCCGTTGCTTTATATGAAGCACAAGGTATGGCTGCTTGGGCCCTTTAA

Upstream 100 bases:

>100_bases
CGTTAGACTGGGTTCTGTTGATTGCGAATGACATCGCAGTTAAGATTTTTGTCAGTAACTTATTTAATCGATAATCACAA
AATTTATAGGAGTGTCTAAT

Downstream 100 bases:

>100_bases
TCTAAAACTATTAAGACAAAGTCGGGATTCCTTCCCGACTTTTTTTGTTGCGTTAAATTACTTTCTATAATCAACATCCT
TTTAAACTTATAAGAACAAT

Product: extracellular protein

Products: NA

Alternate protein names: Immunodominant staphylococcal antigen A [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKKLVSTIVTTSAAAAGLLFAGVLNANADSTYTVKSGDSVWAIAQKFNTTINHVETTNNIKGHYILPGQKLSIKTSSTSS
DNNTSSTTSNTTSSSASTTSSSSTSNTTATTTSTSSTDSTTSSYTGSNLKSYVLSQMQSRTGVSASTWNTIITRESNWQP
YVRNSSSGAYGLFQNMHISSGSVEEQVNAAVALYEAQGMAAWAL

Sequences:

>Translated_204_residues
MKKLVSTIVTTSAAAAGLLFAGVLNANADSTYTVKSGDSVWAIAQKFNTTINHVETTNNIKGHYILPGQKLSIKTSSTSS
DNNTSSTTSNTTSSSASTTSSSSTSNTTATTTSTSSTDSTTSSYTGSNLKSYVLSQMQSRTGVSASTWNTIITRESNWQP
YVRNSSSGAYGLFQNMHISSGSVEEQVNAAVALYEAQGMAAWAL
>Mature_204_residues
MKKLVSTIVTTSAAAAGLLFAGVLNANADSTYTVKSGDSVWAIAQKFNTTINHVETTNNIKGHYILPGQKLSIKTSSTSS
DNNTSSTTSNTTSSSASTTSSSSTSNTTATTTSTSSTDSTTSSYTGSNLKSYVLSQMQSRTGVSASTWNTIITRESNWQP
YVRNSSSGAYGLFQNMHISSGSVEEQVNAAVALYEAQGMAAWAL

Specific function: Is able to cleave peptidoglycan [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase family. IsaA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010618 [H]

Pfam domain/function: PF06737 Transglycosylas [H]

EC number: NA

Molecular weight: Translated: 21336; Mature: 21336

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVSTIVTTSAAAAGLLFAGVLNANADSTYTVKSGDSVWAIAQKFNTTINHVETTNNI
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHCCHHHEEECCCCC
KGHYILPGQKLSIKTSSTSSDNNTSSTTSNTTSSSASTTSSSSTSNTTATTTSTSSTDST
CEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
TSSYTGSNLKSYVLSQMQSRTGVSASTWNTIITRESNWQPYVRNSSSGAYGLFQNMHISS
CCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEECCCCCCEEHEEEEECCC
GSVEEQVNAAVALYEAQGMAAWAL
CCHHHHHHHEEEEEECCCEEEECC
>Mature Secondary Structure
MKKLVSTIVTTSAAAAGLLFAGVLNANADSTYTVKSGDSVWAIAQKFNTTINHVETTNNI
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHCCHHHEEECCCCC
KGHYILPGQKLSIKTSSTSSDNNTSSTTSNTTSSSASTTSSSSTSNTTATTTSTSSTDST
CEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
TSSYTGSNLKSYVLSQMQSRTGVSASTWNTIITRESNWQPYVRNSSSGAYGLFQNMHISS
CCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEECCCCCCEEHEEEEECCC
GSVEEQVNAAVALYEAQGMAAWAL
CCHHHHHHHEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA