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The map label for this gene is sip2 [H]

Identifier: 28379330

GI number: 28379330

Start: 2552544

End: 2553167

Strand: Direct

Name: sip2 [H]

Synonym: lp_2863

Alternate gene names: 28379330

Gene position: 2552544-2553167 (Clockwise)

Preceding gene: 28379329

Following gene: 28379344

Centisome position: 77.16

GC content: 45.83

Gene sequence:

>624_bases
ATGACCACCAAAGTAAAAGTTGTCCTTAGTTGGCTACTCCCCATCATAATTGGTCTGATTATCGCACTTTTGATTCGCCA
ATTCTGGTTCACAGTAGTAAAAGTGGATGGTAATTCCATGCAACCAAACTTGCAAAACAATCAACACGTGGTCGCCGTCA
AAACTAGTACCATCAAACGTGGTAGTGTCATCGTCTTCCACGCATACGGCGTCGATGCCACCCAAGCTGACCACAACGCC
GTTTACGTCAAGCGAGTCGTAGCAGTTGGTGGCGATAAAGTCCGTTATACACATGCTGGTAAACTATACGTCAACAATAA
GCTAGTCAAGCAAACTTATCAGCCTAATCATTATCAACTCACAACTGGGTCTTATATGGCCAACGCCCACAGCCAATTTA
CCGGCTGGACATTAACCAGTTTGAGCCATAATCAGCCAGCTTGGCAGGTCACCGTTACCAACAACCGGGTCCCTAAAGGC
AGTTACTTTGTCCTTGGTGGTCACCGGAGCGTCTCTAATGATAGCCGTAATTGGGGATTTGTCTCCCAAAACAAAGTCAT
TGGCGTTGTTAAGGCTTGGCCGTGGCAGAACCGGCAACAATACATCAATCATTTTCAAAACTAA

Upstream 100 bases:

>100_bases
TACCAACCTTAAGATTTGAACACCTTATCAGCAAGTCGTTAACTGCGACTTGCTTTTTGTTATACTGAAAATATTATTTA
AATAATAAGGAGCCTAATCA

Downstream 100 bases:

>100_bases
CAAATAAACGAATCAACAAAGTTATGAACAACTTGTTGATTCGTTTATTTGTTAACCAGACTTTTATCCACAGTTAATAA
CTTAATGCCGTTATCCACAG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase IB; Leader peptidase IB [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MTTKVKVVLSWLLPIIIGLIIALLIRQFWFTVVKVDGNSMQPNLQNNQHVVAVKTSTIKRGSVIVFHAYGVDATQADHNA
VYVKRVVAVGGDKVRYTHAGKLYVNNKLVKQTYQPNHYQLTTGSYMANAHSQFTGWTLTSLSHNQPAWQVTVTNNRVPKG
SYFVLGGHRSVSNDSRNWGFVSQNKVIGVVKAWPWQNRQQYINHFQN

Sequences:

>Translated_207_residues
MTTKVKVVLSWLLPIIIGLIIALLIRQFWFTVVKVDGNSMQPNLQNNQHVVAVKTSTIKRGSVIVFHAYGVDATQADHNA
VYVKRVVAVGGDKVRYTHAGKLYVNNKLVKQTYQPNHYQLTTGSYMANAHSQFTGWTLTSLSHNQPAWQVTVTNNRVPKG
SYFVLGGHRSVSNDSRNWGFVSQNKVIGVVKAWPWQNRQQYINHFQN
>Mature_206_residues
TTKVKVVLSWLLPIIIGLIIALLIRQFWFTVVKVDGNSMQPNLQNNQHVVAVKTSTIKRGSVIVFHAYGVDATQADHNAV
YVKRVVAVGGDKVRYTHAGKLYVNNKLVKQTYQPNHYQLTTGSYMANAHSQFTGWTLTSLSHNQPAWQVTVTNNRVPKGS
YFVLGGHRSVSNDSRNWGFVSQNKVIGVVKAWPWQNRQQYINHFQN

Specific function: Essential for cell viability [H]

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23404; Mature: 23273

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKVKVVLSWLLPIIIGLIIALLIRQFWFTVVKVDGNSMQPNLQNNQHVVAVKTSTIKR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEEEEECEECC
GSVIVFHAYGVDATQADHNAVYVKRVVAVGGDKVRYTHAGKLYVNNKLVKQTYQPNHYQL
CCEEEEEEECCCCCCCCCCEEEEEEEEECCCCEEEEEECCEEEECCCEEECCCCCCCEEE
TTGSYMANAHSQFTGWTLTSLSHNQPAWQVTVTNNRVPKGSYFVLGGHRSVSNDSRNWGF
ECCCEEECCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCE
VSQNKVIGVVKAWPWQNRQQYINHFQN
EECCCEEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
TTKVKVVLSWLLPIIIGLIIALLIRQFWFTVVKVDGNSMQPNLQNNQHVVAVKTSTIKR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEEEEECEECC
GSVIVFHAYGVDATQADHNAVYVKRVVAVGGDKVRYTHAGKLYVNNKLVKQTYQPNHYQL
CCEEEEEEECCCCCCCCCCEEEEEEEEECCCCEEEEEECCEEEECCCEEECCCCCCCEEE
TTGSYMANAHSQFTGWTLTSLSHNQPAWQVTVTNNRVPKGSYFVLGGHRSVSNDSRNWGF
ECCCEEECCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCE
VSQNKVIGVVKAWPWQNRQQYINHFQN
EECCCEEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA