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The map label for this gene is 28378402

Identifier: 28378402

GI number: 28378402

Start: 1556098

End: 1556874

Strand: Direct

Name: 28378402

Synonym: lp_1716

Alternate gene names: NA

Gene position: 1556098-1556874 (Clockwise)

Preceding gene: 28378401

Following gene: 28378403

Centisome position: 47.04

GC content: 45.17

Gene sequence:

>777_bases
ATGGAAACAGAACAGCGACAGCAACGAAGAATTGCGGTGTATCACTTAATTGTCACACTTTTGACACTCTGGTCAGCAGT
TAACGTGATCCTATTATCGTTTCATATCGGTGATTGGCACGTTGAAACCCGCATCAGTAACGGCTTATTAGTCATGTTTG
CGGTGGACTACTTTGTGCGCCTAATTCGTTCTCGAGATCGGAAGACTTTTCTCATTCATTCAGCGTTCGATTTGATGGGG
ATTATTCCCATGCACCCGGTGTTTGCACTCTTTCGACTTGGGCGTTTGGCACGGATGGTCCAATATCACCATTTGTTCTG
GAAGCTCGGACTGGATGGTAAGTGGACGCACGATTTTCACCGCTTTATCTATAGCACCGGGTTTATCTACCTGTTTTCAA
TTAGTATTGCGATTATTGTTCTTAGTGCGTTGCTCTTTTCCGTTTTCGAGCATCAAAGCCTGTCAGATTCACTGTGGTGG
GCCATCACAACGGCGACTACCGTGGGTTATGGTGACGATACGCCCCATACTGCCGTTGGCAAAGTGATCGCGGTCGGGCT
GATGTTCGGTGGGATTGGTTTTATTGGTTTGTTAACGAGTACGATTACTGACTTCTTCACAACGCAAGCCAGTCAGAATG
TCACGATCGAGGAACCACAGCATGATGACGAGCTGCGACAACTACTGATTAAAATTGACACGTTGACGACGAAGGTCGAT
CATTTACAAAATCAAGTTAAACGTTTAGAAAAATCAGGCTACAAAAAACAACATTGA

Upstream 100 bases:

>100_bases
AACAAATTAGTAAAGCTCACTTAATTTTTCGCACTTATCGTGGTTATTTTTATGAAAGTGGACTATATTATTACCAGTTT
ATAAAATAGGGGTAAGCAGG

Downstream 100 bases:

>100_bases
ATTTTCGGACCGTTGGATGCCCTTAATGGGGCGCAGCGGTCCGTTTTGCTATGCTATAATAACGGTAACAAATTCGAAAC
GGTGGTGGTGAGATGGGACA

Product: potassium transport protein

Products: NA

Alternate protein names: KvAP [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
METEQRQQRRIAVYHLIVTLLTLWSAVNVILLSFHIGDWHVETRISNGLLVMFAVDYFVRLIRSRDRKTFLIHSAFDLMG
IIPMHPVFALFRLGRLARMVQYHHLFWKLGLDGKWTHDFHRFIYSTGFIYLFSISIAIIVLSALLFSVFEHQSLSDSLWW
AITTATTVGYGDDTPHTAVGKVIAVGLMFGGIGFIGLLTSTITDFFTTQASQNVTIEEPQHDDELRQLLIKIDTLTTKVD
HLQNQVKRLEKSGYKKQH

Sequences:

>Translated_258_residues
METEQRQQRRIAVYHLIVTLLTLWSAVNVILLSFHIGDWHVETRISNGLLVMFAVDYFVRLIRSRDRKTFLIHSAFDLMG
IIPMHPVFALFRLGRLARMVQYHHLFWKLGLDGKWTHDFHRFIYSTGFIYLFSISIAIIVLSALLFSVFEHQSLSDSLWW
AITTATTVGYGDDTPHTAVGKVIAVGLMFGGIGFIGLLTSTITDFFTTQASQNVTIEEPQHDDELRQLLIKIDTLTTKVD
HLQNQVKRLEKSGYKKQH
>Mature_258_residues
METEQRQQRRIAVYHLIVTLLTLWSAVNVILLSFHIGDWHVETRISNGLLVMFAVDYFVRLIRSRDRKTFLIHSAFDLMG
IIPMHPVFALFRLGRLARMVQYHHLFWKLGLDGKWTHDFHRFIYSTGFIYLFSISIAIIVLSALLFSVFEHQSLSDSLWW
AITTATTVGYGDDTPHTAVGKVIAVGLMFGGIGFIGLLTSTITDFFTTQASQNVTIEEPQHDDELRQLLIKIDTLTTKVD
HLQNQVKRLEKSGYKKQH

Specific function: Mediates a strong voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassi

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the potassium channel family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17544122, Length=208, Percent_Identity=25, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099 [H]

Pfam domain/function: PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 29691; Mature: 29691

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METEQRQQRRIAVYHLIVTLLTLWSAVNVILLSFHIGDWHVETRISNGLLVMFAVDYFVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHHH
LIRSRDRKTFLIHSAFDLMGIIPMHPVFALFRLGRLARMVQYHHLFWKLGLDGKWTHDFH
HHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHH
RFIYSTGFIYLFSISIAIIVLSALLFSVFEHQSLSDSLWWAITTATTVGYGDDTPHTAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEHHEEECCCCCCCHHHHH
KVIAVGLMFGGIGFIGLLTSTITDFFTTQASQNVTIEEPQHDDELRQLLIKIDTLTTKVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHH
HLQNQVKRLEKSGYKKQH
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
METEQRQQRRIAVYHLIVTLLTLWSAVNVILLSFHIGDWHVETRISNGLLVMFAVDYFVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHHH
LIRSRDRKTFLIHSAFDLMGIIPMHPVFALFRLGRLARMVQYHHLFWKLGLDGKWTHDFH
HHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHH
RFIYSTGFIYLFSISIAIIVLSALLFSVFEHQSLSDSLWWAITTATTVGYGDDTPHTAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEHHEEECCCCCCCHHHHH
KVIAVGLMFGGIGFIGLLTSTITDFFTTQASQNVTIEEPQHDDELRQLLIKIDTLTTKVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHH
HLQNQVKRLEKSGYKKQH
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]