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The map label for this gene is fabZ2 [H]

Identifier: 28378367

GI number: 28378367

Start: 1527904

End: 1528317

Strand: Direct

Name: fabZ2 [H]

Synonym: lp_1677

Alternate gene names: 28378367

Gene position: 1527904-1528317 (Clockwise)

Preceding gene: 28378366

Following gene: 28378368

Centisome position: 46.18

GC content: 45.65

Gene sequence:

>414_bases
ATGGAAGTTACGGATTTAATTCCCCAACGGTTTCCGCTGCAATTATTAGACCGTATCGTAGCGGTCCAACCAGGTGTCAG
CGCAACAGCGGAAAAATTAGTCACGATTAATGAATGGTTTTTTCAGAGTCAGACACTGACCGGAAGAACGATGATTCGGC
CAGTATTATTAGAAATTTTGGCTCAAACGGGAGTTGTGGCTTTACTATCGATGCCAGAACATCATGGTAATAACGTCTTT
TTTGGCGGAATTCGGCAGGCTGATTTTAAGACGGATGTGCGCCCAGGTGACCGGTTAGAAGCGATGGTAACGTTAACTAA
GTTGCGTCGTCAAATCGGAACAGGCCATGGCGTGATTACCTGTGCTGGTCGTGAGGTTGTTAGTGCTGATTTAACCTTTG
TAATGCAAGCCTGA

Upstream 100 bases:

>100_bases
CTAGCCCAGTTAGTGGGATCGTTAAAGAAGTTTTAATTAAGAATGCAACTATGGTTGAATTTGATGAACCATTGTTTGCA
ATTGAGGAGACGACCGTTTA

Downstream 100 bases:

>100_bases
AGGAGGTATGGCGATTGTTTAAAAAAGTCTTAGTCGCGAACCGTGGTGAAATTGCGGTCCAAGTTATTCGCGCGCTTCAT
GAGATGGGGATTAAAGCGGT

Product: (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MEVTDLIPQRFPLQLLDRIVAVQPGVSATAEKLVTINEWFFQSQTLTGRTMIRPVLLEILAQTGVVALLSMPEHHGNNVF
FGGIRQADFKTDVRPGDRLEAMVTLTKLRRQIGTGHGVITCAGREVVSADLTFVMQA

Sequences:

>Translated_137_residues
MEVTDLIPQRFPLQLLDRIVAVQPGVSATAEKLVTINEWFFQSQTLTGRTMIRPVLLEILAQTGVVALLSMPEHHGNNVF
FGGIRQADFKTDVRPGDRLEAMVTLTKLRRQIGTGHGVITCAGREVVSADLTFVMQA
>Mature_137_residues
MEVTDLIPQRFPLQLLDRIVAVQPGVSATAEKLVTINEWFFQSQTLTGRTMIRPVLLEILAQTGVVALLSMPEHHGNNVF
FGGIRQADFKTDVRPGDRLEAMVTLTKLRRQIGTGHGVITCAGREVVSADLTFVMQA

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=133, Percent_Identity=37.593984962406, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 15115; Mature: 15115

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTDLIPQRFPLQLLDRIVAVQPGVSATAEKLVTINEWFFQSQTLTGRTMIRPVLLEIL
CCCHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AQTGVVALLSMPEHHGNNVFFGGIRQADFKTDVRPGDRLEAMVTLTKLRRQIGTGHGVIT
HHCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
CAGREVVSADLTFVMQA
ECCCHHHHCCEEEEECC
>Mature Secondary Structure
MEVTDLIPQRFPLQLLDRIVAVQPGVSATAEKLVTINEWFFQSQTLTGRTMIRPVLLEIL
CCCHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AQTGVVALLSMPEHHGNNVFFGGIRQADFKTDVRPGDRLEAMVTLTKLRRQIGTGHGVIT
HHCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
CAGREVVSADLTFVMQA
ECCCHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA