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The map label for this gene is accB2 [H]

Identifier: 28378366

GI number: 28378366

Start: 1527443

End: 1527904

Strand: Direct

Name: accB2 [H]

Synonym: lp_1676

Alternate gene names: 28378366

Gene position: 1527443-1527904 (Clockwise)

Preceding gene: 28378365

Following gene: 28378367

Centisome position: 46.17

GC content: 48.48

Gene sequence:

>462_bases
ATGAGTATGACGGATACGGAAGCGATGACCGCCCTGATCAATCAGTTTAATCAATCCAGCGCTCAAGTCATGGACGTCAA
GACGACAACCTTTGAACTGCATTTGAATAAACAAGCTGAAACTGCTGAGACAAATTCAGCGCGTTCACAGCCGGCAGTGA
CCGACTCCGCGGTACCAGTGGTCAAACCGACGACTGAAGTGGCGACTCAATCGGGAACAACGATGGTCACGGCGCCCCTA
GTTGGGGTGGCTTACTTAGCTGCCGACCCGAAACAGGCGCCGTTTGTTCAGGTGGGTGATCGTGTCAAGTCAGGGGAAAC
CTTGTGTGTAATCGAAGCGATGAAAATGATCAACGAAGTCCCTAGCCCAGTTAGTGGGATCGTTAAAGAAGTTTTAATTA
AGAATGCAACTATGGTTGAATTTGATGAACCATTGTTTGCAATTGAGGAGACGACCGTTTAA

Upstream 100 bases:

>100_bases
CGCCAGCAACTCAACATCAAGCCGCAACCTATGCTTTGAGTAATTCATTTGGTTTTGGGGGCCATAATGCCGTGGTTGCC
TTTAAGAAGTGGGTGAATGT

Downstream 100 bases:

>100_bases
TGGAAGTTACGGATTTAATTCCCCAACGGTTTCCGCTGCAATTATTAGACCGTATCGTAGCGGTCCAACCAGGTGTCAGC
GCAACAGCGGAAAAATTAGT

Product: acetyl-CoA carboxylase, biotin carboxyl carrier protein

Products: ADP; phosphate; malonyl-CoA

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MSMTDTEAMTALINQFNQSSAQVMDVKTTTFELHLNKQAETAETNSARSQPAVTDSAVPVVKPTTEVATQSGTTMVTAPL
VGVAYLAADPKQAPFVQVGDRVKSGETLCVIEAMKMINEVPSPVSGIVKEVLIKNATMVEFDEPLFAIEETTV

Sequences:

>Translated_153_residues
MSMTDTEAMTALINQFNQSSAQVMDVKTTTFELHLNKQAETAETNSARSQPAVTDSAVPVVKPTTEVATQSGTTMVTAPL
VGVAYLAADPKQAPFVQVGDRVKSGETLCVIEAMKMINEVPSPVSGIVKEVLIKNATMVEFDEPLFAIEETTV
>Mature_152_residues
SMTDTEAMTALINQFNQSSAQVMDVKTTTFELHLNKQAETAETNSARSQPAVTDSAVPVVKPTTEVATQSGTTMVTAPLV
GVAYLAADPKQAPFVQVGDRVKSGETLCVIEAMKMINEVPSPVSGIVKEVLIKNATMVEFDEPLFAIEETTV

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=102, Percent_Identity=41.1764705882353, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: 6.4.1.2

Molecular weight: Translated: 16350; Mature: 16219

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTDTEAMTALINQFNQSSAQVMDVKTTTFELHLNKQAETAETNSARSQPAVTDSAVPV
CCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
VKPTTEVATQSGTTMVTAPLVGVAYLAADPKQAPFVQVGDRVKSGETLCVIEAMKMINEV
CCCCHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEHHHHHHHHHHHC
PSPVSGIVKEVLIKNATMVEFDEPLFAIEETTV
CCCHHHHHHHHHHCCCCEEEECCCEEEEECCCC
>Mature Secondary Structure 
SMTDTEAMTALINQFNQSSAQVMDVKTTTFELHLNKQAETAETNSARSQPAVTDSAVPV
CCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
VKPTTEVATQSGTTMVTAPLVGVAYLAADPKQAPFVQVGDRVKSGETLCVIEAMKMINEV
CCCCHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEHHHHHHHHHHHC
PSPVSGIVKEVLIKNATMVEFDEPLFAIEETTV
CCCHHHHHHHHHHCCCCEEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; acetyl-CoA; HCO3-

Specific reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA