BacMap

Definition	Lactobacillus plantarum WCFS1, complete genome.
Accession	NC_004567
Length	3,308,274

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The map label for this gene is fabG1 [H]

Identifier: 28378364

GI number: 28378364

Start: 1525467

End: 1526195

Strand: Direct

Name: fabG1 [H]

Synonym: lp_1674

Alternate gene names: 28378364

Gene position: 1525467-1526195 (Clockwise)

Preceding gene: 28378363

Following gene: 28378365

Centisome position: 46.11

GC content: 47.6

Gene sequence:

>729_bases
GTGAGCGTGGATGAAGTGATTTTAGTCACTGGAGCTGCTAAGGGTATTGGTTTGGCAACAGTCAAACGGTTGGCAGCTCA
GGGGGCCAGCGTTATTTTAAACGTTCATCATGAAATTGAAGCGGCCGATTGGCAAGCATTAACGGCTGAATATCCAAGGT
TGACGCAATTAGTTGGTGATGTGAGCGATGATCAAACGGCGGCTGATTTAATTGAGACCGTGATGACAAATTTTGGTCGC
TTGGATGGACTCGTGAATAACGCTGGTGTGACCCATGATCAGTTATTAACGCGGCTACACGCGGAAGATTTCATGAGTGT
GATTCAAACAAATTTATTGGGCACATTTAATATGACCAAATACGCTTTAAAAGTCATGCAGCGACAGCGACAAGGCGCCA
TCGTTAATGTTGCTAGTGTGGTCGGGTTACATGGCAATATCGGCCAGGCGAACTATGCGGCTAGTAAGGCTGGAATTATT
GGTTTAACTAAAACGACGGCAAAGGAAGCGGCTCGGCGCCAAGTGCGGTGTAATGCGGTGGCCCCAGGAATGATTACGAC
GGCCATGACGGCACAATTGAATGACCGTGTAACGGCGGCTGCCTTAAGTGATATTCCACTCAAACGCTTTGGGACGCCCG
ACGAAATTGCCCAAGCAATTGACTTTTTATTGCACCAACCGTACTTAACGGGACAAGTGCTAACAGTTGACGGTGGCATG
ACGATATAA

Upstream 100 bases:

>100_bases
TTAGCAACTTTTGCCAAACAAACATTGCCAGGGGTAAGGGTTTGGTCAATTGAAGATGTGACAGATTGGCAGAATTATTG
TCAGGATACTGAGGAGGTAC

Downstream 100 bases:

>100_bases
GATATGGGAGGTTATCCAATGACAGAACGAGTAGTTGTGACTGGAATGGGTGCGGTGACGCCCCTCGGTAATAGTGTTGA
TGAATTTTTAACGGGGTTAT

Product: 3-oxoacyl-[acyl-carrier protein] reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSVDEVILVTGAAKGIGLATVKRLAAQGASVILNVHHEIEAADWQALTAEYPRLTQLVGDVSDDQTAADLIETVMTNFGR
LDGLVNNAGVTHDQLLTRLHAEDFMSVIQTNLLGTFNMTKYALKVMQRQRQGAIVNVASVVGLHGNIGQANYAASKAGII
GLTKTTAKEAARRQVRCNAVAPGMITTAMTAQLNDRVTAAALSDIPLKRFGTPDEIAQAIDFLLHQPYLTGQVLTVDGGM
TI

Sequences:

>Translated_242_residues
MSVDEVILVTGAAKGIGLATVKRLAAQGASVILNVHHEIEAADWQALTAEYPRLTQLVGDVSDDQTAADLIETVMTNFGR
LDGLVNNAGVTHDQLLTRLHAEDFMSVIQTNLLGTFNMTKYALKVMQRQRQGAIVNVASVVGLHGNIGQANYAASKAGII
GLTKTTAKEAARRQVRCNAVAPGMITTAMTAQLNDRVTAAALSDIPLKRFGTPDEIAQAIDFLLHQPYLTGQVLTVDGGM
TI
>Mature_241_residues
SVDEVILVTGAAKGIGLATVKRLAAQGASVILNVHHEIEAADWQALTAEYPRLTQLVGDVSDDQTAADLIETVMTNFGRL
DGLVNNAGVTHDQLLTRLHAEDFMSVIQTNLLGTFNMTKYALKVMQRQRQGAIVNVASVVGLHGNIGQANYAASKAGIIG
LTKTTAKEAARRQVRCNAVAPGMITTAMTAQLNDRVTAAALSDIPLKRFGTPDEIAQAIDFLLHQPYLTGQVLTVDGGMT
I

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=39.6694214876033, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI15277342, Length=245, Percent_Identity=38.3673469387755, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=32.4110671936759, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=30.4347826086957, Blast_Score=114, Evalue=5e-26,
Organism=Homo sapiens, GI4504505, Length=199, Percent_Identity=32.6633165829146, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=31.8965517241379, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=30.1652892561983, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=37.6288659793814, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=32.6359832635983, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=30.7359307359307, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=27.4193548387097, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=37.6470588235294, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI150247226, Length=196, Percent_Identity=30.1020408163265, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI7657478, Length=204, Percent_Identity=31.3725490196078, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4557649, Length=201, Percent_Identity=30.8457711442786, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=30.5220883534137, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=26.1044176706827, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI19743808, Length=190, Percent_Identity=31.0526315789474, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI109715829, Length=234, Percent_Identity=24.7863247863248, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=207, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=42.9166666666667, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=35.8870967741936, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=31.1203319502075, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=35.3413654618474, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=35.8870967741936, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=32.3770491803279, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=29.4605809128631, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082160, Length=239, Percent_Identity=26.3598326359833, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=28.6885245901639, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=30.9236947791165, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787526, Length=193, Percent_Identity=31.6062176165803, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=29.2887029288703, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=25.968992248062, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=38.5892116182573, Blast_Score=143, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=36.734693877551, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=33.8709677419355, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=30.4, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17568967, Length=255, Percent_Identity=29.8039215686275, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=29.8449612403101, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=30.1960784313725, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=29.6153846153846, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=27.8195488721804, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=30.1960784313725, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=30.6513409961686, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=27.4809160305344, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=27.9693486590038, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=29.3436293436293, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=30.1960784313725, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=31.3492063492063, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=28.735632183908, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=28.0769230769231, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=29.0076335877863, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=27.6923076923077, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=26.8199233716475, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=27.8884462151394, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=28.1853281853282, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=28.8461538461538, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=27.843137254902, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=28.7878787878788, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=30, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=28.7958115183246, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=28.7958115183246, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=25.1282051282051, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=231, Percent_Identity=32.4675324675325, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6324126, Length=185, Percent_Identity=31.3513513513514, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6322227, Length=214, Percent_Identity=26.6355140186916, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=219, Percent_Identity=28.310502283105, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320089, Length=200, Percent_Identity=26.5, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=39.0946502057613, Blast_Score=143, Evalue=9e-35,
Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=35.546875, Blast_Score=137, Evalue=6e-33,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=32.7935222672065, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI18859837, Length=228, Percent_Identity=34.6491228070175, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=33.8709677419355, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=35.655737704918, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=31.8548387096774, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=32.3886639676113, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=31.9838056680162, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24665243, Length=205, Percent_Identity=31.7073170731707, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221331218, Length=205, Percent_Identity=31.7073170731707, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24665247, Length=204, Percent_Identity=30.3921568627451, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI116007236, Length=242, Percent_Identity=29.3388429752066, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221331216, Length=204, Percent_Identity=30.3921568627451, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641388, Length=245, Percent_Identity=27.7551020408163, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644337, Length=172, Percent_Identity=33.7209302325581, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356301, Length=193, Percent_Identity=29.0155440414508, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24656154, Length=254, Percent_Identity=26.7716535433071, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19922628, Length=254, Percent_Identity=26.7716535433071, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28571387, Length=235, Percent_Identity=27.2340425531915, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581726, Length=143, Percent_Identity=29.3706293706294, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007238, Length=178, Percent_Identity=32.5842696629214, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24648693, Length=240, Percent_Identity=26.25, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21355889, Length=240, Percent_Identity=26.25, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=26.5625, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25748; Mature: 25617

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDEVILVTGAAKGIGLATVKRLAAQGASVILNVHHEIEAADWQALTAEYPRLTQLVGD
CCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECHHHCHHHHHHHHHCCHHHHHHHCC
VSDDQTAADLIETVMTNFGRLDGLVNNAGVTHDQLLTRLHAEDFMSVIQTNLLGTFNMTK
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YALKVMQRQRQGAIVNVASVVGLHGNIGQANYAASKAGIIGLTKTTAKEAARRQVRCNAV
HHHHHHHHHHCCCEEEHHHHHHCCCCCCCCHHHHCCCCEEEECHHHHHHHHHHHHHCCCC
APGMITTAMTAQLNDRVTAAALSDIPLKRFGTPDEIAQAIDFLLHQPYLTGQVLTVDGGM
CCCHHHHHHHHHHCCHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCC
TI
CC
>Mature Secondary Structure 
SVDEVILVTGAAKGIGLATVKRLAAQGASVILNVHHEIEAADWQALTAEYPRLTQLVGD
CCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECHHHCHHHHHHHHHCCHHHHHHHCC
VSDDQTAADLIETVMTNFGRLDGLVNNAGVTHDQLLTRLHAEDFMSVIQTNLLGTFNMTK
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YALKVMQRQRQGAIVNVASVVGLHGNIGQANYAASKAGIIGLTKTTAKEAARRQVRCNAV
HHHHHHHHHHCCCEEEHHHHHHCCCCCCCCHHHHCCCCEEEECHHHHHHHHHHHHHCCCC
APGMITTAMTAQLNDRVTAAALSDIPLKRFGTPDEIAQAIDFLLHQPYLTGQVLTVDGGM
CCCHHHHHHHHHHCCHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCC
TI
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]