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The map label for this gene is ftsY [H]

Identifier: 28378331

GI number: 28378331

Start: 1488793

End: 1490340

Strand: Direct

Name: ftsY [H]

Synonym: lp_1633

Alternate gene names: 28378331

Gene position: 1488793-1490340 (Clockwise)

Preceding gene: 28378330

Following gene: 28378332

Centisome position: 45.0

GC content: 50.32

Gene sequence:

>1548_bases
GTGTTGAAGATGGGACTATTTAGTCGGTTAAAAAAAGCGTTTAGTTTACCAGAATCAGATGACGCTCAAACAACGTCAGC
TGCCAGTGAAGCACCTGCAACGACGAGTCAAGCTAACGCACCGGTCAGTGACGACCGGGCCCCTTCGTCACAACAGTTAG
CTCGCTCGGAGGGCGCAACAACTGAATCAACTGCGACACCGGTGTCCAGTACAGCCGTAAGCGAAGCGACAAGCACTGCG
GACGAACCAGCGACAGTAAAATCGGCAGCTACTAGTGAAGCCCCGGCCGATAGCACGGCGGCAGTGAGTGCACAGTCTGG
TTCACAAGCATCACTGCAATCGGCGACGGTGTCGGAAGCGCCACTCACAGCCAGTGCAATGGTTGCCCAGTCACTAGCTG
CATTAAGTGCGAGTGCGGCACAAGTTAGTCAAGCGGCCGCGAGCGACGTGGCGTTAGCGACTAAGTCTGATGCGGTAGTT
GAAGGCAATGCTATGTCAGAATCAGTAGCCAGTACGGCGCCAGCAGTCAAGTCATCAGCGACGACTGCGACTGAATCCGC
CGCACCGACTGTTAATGCGGCGGCTGATTCGGAATCGGCTGAGCCGGAGCCAACTGAGGCAGAACGTTATGATGAAGGAC
TGAAAAAGTCGCGGAAAACGTTTGGTGATCGTATCAATGCCTTCTTGGCTAATTTCCGCCATGTCGACGAAGCGTTCTTC
GATGATTTGGAAGATACGCTGATCGAATCTGATGTGGGTTATGAGACCGCGATGCGAATTAGTGACGAGCTACGTGACGA
AGTTAAATTAAAGAACGCGAAGAGCAAGAAAGAAATTTCAAGCGTCATCGTCGAAAAGCTCGTTGATATGTACGGTGAAG
CTGGTGAAGGCGAGGATAACTCGATTCACATGGCTAAGAGTGGTCCAACCGTTATTTTATTTGTCGGGGTCAATGGTGCT
GGTAAGACCACTACAATCGGTAAGATGGCGAACATGTACAAGCAGCAAGGCAAGAAGGTCTTGTTGGCGGCTTGTGATAC
GTTTAGAGCTGGTGCAATCCAGCAGTTGCAAGTCTGGGGGCAACGAGACGGGGTTGACGTGGTCGCTAAGGCCGAAAAAA
GTGATCCAGCGGCCGTTTGCTTTGACGCGGTTAAGAAGGCTAAGGCCGAAGATTATGACGTGCTCTTTGTGGACACTGCT
GGTCGGCTTCAAAACAAAGTCAACTTGATGAATGAATTGGAAAAGATCAAGCGGGTCATCACCCGTGAAATCCCTGATGC
ACCACACGAGGTCTTACTGGTGCTGGATGCCACGACTGGGCAAAACGCGCTGAACCAAGCCAAGTTGTTTAAACAGTCGA
CGGATGTCAGTGGGATTGTGTTAACTAAACTTGATGGTACGGCACGTGGTGGGATCGTCTTAGCTATTCGTAATGAATTG
CATCTTGCTGTAAAGTACGTTGGTTTAGGTGAAAAGGTGACTGATTTACGACCATTCAATGCCAATGACTTTGTCTACGG
GTTATTTAAAGATATTATCACGGGTTAA

Upstream 100 bases:

>100_bases
TGACGTACTTTATGGGGTAACCATGGAAGAGTCAGGTGTCTCCAAGATGGTCTCAGTCTCCTTGGCAGATTTAAAAGATG
AACAAAAATAATTAAAGGAA

Downstream 100 bases:

>100_bases
ATCAGTTGATGATGGTCTTAAATTGAAAGCCAGTTAACGAAATGGTAATTGTTCTCAGCACGAGGACGATTACCATTTAT
TTTTACCACAAATGGCGACT

Product: signal recognition particle receptor FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MLKMGLFSRLKKAFSLPESDDAQTTSAASEAPATTSQANAPVSDDRAPSSQQLARSEGATTESTATPVSSTAVSEATSTA
DEPATVKSAATSEAPADSTAAVSAQSGSQASLQSATVSEAPLTASAMVAQSLAALSASAAQVSQAAASDVALATKSDAVV
EGNAMSESVASTAPAVKSSATTATESAAPTVNAAADSESAEPEPTEAERYDEGLKKSRKTFGDRINAFLANFRHVDEAFF
DDLEDTLIESDVGYETAMRISDELRDEVKLKNAKSKKEISSVIVEKLVDMYGEAGEGEDNSIHMAKSGPTVILFVGVNGA
GKTTTIGKMANMYKQQGKKVLLAACDTFRAGAIQQLQVWGQRDGVDVVAKAEKSDPAAVCFDAVKKAKAEDYDVLFVDTA
GRLQNKVNLMNELEKIKRVITREIPDAPHEVLLVLDATTGQNALNQAKLFKQSTDVSGIVLTKLDGTARGGIVLAIRNEL
HLAVKYVGLGEKVTDLRPFNANDFVYGLFKDIITG

Sequences:

>Translated_515_residues
MLKMGLFSRLKKAFSLPESDDAQTTSAASEAPATTSQANAPVSDDRAPSSQQLARSEGATTESTATPVSSTAVSEATSTA
DEPATVKSAATSEAPADSTAAVSAQSGSQASLQSATVSEAPLTASAMVAQSLAALSASAAQVSQAAASDVALATKSDAVV
EGNAMSESVASTAPAVKSSATTATESAAPTVNAAADSESAEPEPTEAERYDEGLKKSRKTFGDRINAFLANFRHVDEAFF
DDLEDTLIESDVGYETAMRISDELRDEVKLKNAKSKKEISSVIVEKLVDMYGEAGEGEDNSIHMAKSGPTVILFVGVNGA
GKTTTIGKMANMYKQQGKKVLLAACDTFRAGAIQQLQVWGQRDGVDVVAKAEKSDPAAVCFDAVKKAKAEDYDVLFVDTA
GRLQNKVNLMNELEKIKRVITREIPDAPHEVLLVLDATTGQNALNQAKLFKQSTDVSGIVLTKLDGTARGGIVLAIRNEL
HLAVKYVGLGEKVTDLRPFNANDFVYGLFKDIITG
>Mature_515_residues
MLKMGLFSRLKKAFSLPESDDAQTTSAASEAPATTSQANAPVSDDRAPSSQQLARSEGATTESTATPVSSTAVSEATSTA
DEPATVKSAATSEAPADSTAAVSAQSGSQASLQSATVSEAPLTASAMVAQSLAALSASAAQVSQAAASDVALATKSDAVV
EGNAMSESVASTAPAVKSSATTATESAAPTVNAAADSESAEPEPTEAERYDEGLKKSRKTFGDRINAFLANFRHVDEAFF
DDLEDTLIESDVGYETAMRISDELRDEVKLKNAKSKKEISSVIVEKLVDMYGEAGEGEDNSIHMAKSGPTVILFVGVNGA
GKTTTIGKMANMYKQQGKKVLLAACDTFRAGAIQQLQVWGQRDGVDVVAKAEKSDPAAVCFDAVKKAKAEDYDVLFVDTA
GRLQNKVNLMNELEKIKRVITREIPDAPHEVLLVLDATTGQNALNQAKLFKQSTDVSGIVLTKLDGTARGGIVLAIRNEL
HLAVKYVGLGEKVTDLRPFNANDFVYGLFKDIITG

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=288, Percent_Identity=29.8611111111111, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226371618, Length=200, Percent_Identity=35, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI295424842, Length=311, Percent_Identity=29.2604501607717, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI23308697, Length=311, Percent_Identity=29.2604501607717, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI89061728, Length=135, Percent_Identity=32.5925925925926, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1789874, Length=303, Percent_Identity=45.2145214521452, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1788963, Length=292, Percent_Identity=34.5890410958904, Blast_Score=157, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17539958, Length=271, Percent_Identity=30.9963099630996, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI193206261, Length=296, Percent_Identity=31.0810810810811, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325345, Length=305, Percent_Identity=31.8032786885246, Blast_Score=156, Evalue=6e-39,
Organism=Drosophila melanogaster, GI17647949, Length=271, Percent_Identity=30.6273062730627, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641198, Length=308, Percent_Identity=30.5194805194805, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 53960; Mature: 53960

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKMGLFSRLKKAFSLPESDDAQTTSAASEAPATTSQANAPVSDDRAPSSQQLARSEGAT
CCCHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
TESTATPVSSTAVSEATSTADEPATVKSAATSEAPADSTAAVSAQSGSQASLQSATVSEA
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHCCCC
PLTASAMVAQSLAALSASAAQVSQAAASDVALATKSDAVVEGNAMSESVASTAPAVKSSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCHHHHHHHHCCHHHCCC
TTATESAAPTVNAAADSESAEPEPTEAERYDEGLKKSRKTFGDRINAFLANFRHVDEAFF
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDLEDTLIESDVGYETAMRISDELRDEVKLKNAKSKKEISSVIVEKLVDMYGEAGEGEDN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
SIHMAKSGPTVILFVGVNGAGKTTTIGKMANMYKQQGKKVLLAACDTFRAGAIQQLQVWG
CEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHHHHC
QRDGVDVVAKAEKSDPAAVCFDAVKKAKAEDYDVLFVDTAGRLQNKVNLMNELEKIKRVI
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
TREIPDAPHEVLLVLDATTGQNALNQAKLFKQSTDVSGIVLTKLDGTARGGIVLAIRNEL
HHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCE
HLAVKYVGLGEKVTDLRPFNANDFVYGLFKDIITG
EEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLKMGLFSRLKKAFSLPESDDAQTTSAASEAPATTSQANAPVSDDRAPSSQQLARSEGAT
CCCHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
TESTATPVSSTAVSEATSTADEPATVKSAATSEAPADSTAAVSAQSGSQASLQSATVSEA
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHCCCC
PLTASAMVAQSLAALSASAAQVSQAAASDVALATKSDAVVEGNAMSESVASTAPAVKSSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCHHHHHHHHCCHHHCCC
TTATESAAPTVNAAADSESAEPEPTEAERYDEGLKKSRKTFGDRINAFLANFRHVDEAFF
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDLEDTLIESDVGYETAMRISDELRDEVKLKNAKSKKEISSVIVEKLVDMYGEAGEGEDN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
SIHMAKSGPTVILFVGVNGAGKTTTIGKMANMYKQQGKKVLLAACDTFRAGAIQQLQVWG
CEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHHHHC
QRDGVDVVAKAEKSDPAAVCFDAVKKAKAEDYDVLFVDTAGRLQNKVNLMNELEKIKRVI
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
TREIPDAPHEVLLVLDATTGQNALNQAKLFKQSTDVSGIVLTKLDGTARGGIVLAIRNEL
HHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCE
HLAVKYVGLGEKVTDLRPFNANDFVYGLFKDIITG
EEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]