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The map label for this gene is xseB

Identifier: 28378302

GI number: 28378302

Start: 1456774

End: 1457004

Strand: Direct

Name: xseB

Synonym: lp_1601

Alternate gene names: 28378302

Gene position: 1456774-1457004 (Clockwise)

Preceding gene: 28378301

Following gene: 28378303

Centisome position: 44.03

GC content: 41.99

Gene sequence:

>231_bases
ATGGCTGAACAACCAACTTTTGAACAGAATTTATCACAATTAGAGACGATCGTAAACCAATTAGAGCAGGGTGATGTTCC
TTTAGAACAAGCCTTGGATCAATTTCAAAAGGGCGTGGCACTTAGCAAGCAGTTGCAAGCAACCCTTGAAGGTGCTGAAA
AGACGCTCACTAAGATGATGAATGAAAATGGCGACGAAGTTCCATTTGAGCAAGCTGACGCCAATGAATAA

Upstream 100 bases:

>100_bases
TTCACGGGGTCAAACAATTGCAGCCAGAACAAACGGTTGCAATTCACATGGCTGATGGTGAGGCTCAGGCACAGATTACG
AAGATTGATGGAGGAAAATA

Downstream 100 bases:

>100_bases
GCAATTATTAACTGAATTTGAATCCAAGTGGCGTCCTCAGATTAATCAGTATTTAGATGAGCAGCTTCAAGCGTGTTCTG
ACCAATCAACCCTGACTGAC

Product: exodeoxyribonuclease VII small subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII small subunit; Exonuclease VII small subunit

Number of amino acids: Translated: 76; Mature: 75

Protein sequence:

>76_residues
MAEQPTFEQNLSQLETIVNQLEQGDVPLEQALDQFQKGVALSKQLQATLEGAEKTLTKMMNENGDEVPFEQADANE

Sequences:

>Translated_76_residues
MAEQPTFEQNLSQLETIVNQLEQGDVPLEQALDQFQKGVALSKQLQATLEGAEKTLTKMMNENGDEVPFEQADANE
>Mature_75_residues
AEQPTFEQNLSQLETIVNQLEQGDVPLEQALDQFQKGVALSKQLQATLEGAEKTLTKMMNENGDEVPFEQADANE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1722

COG function: function code L; Exonuclease VII small subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseB family

Homologues:

Organism=Escherichia coli, GI1786624, Length=66, Percent_Identity=46.969696969697, Blast_Score=61, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7S_LACPL (Q88WM6)

Other databases:

- EMBL:   AL935256
- RefSeq:   NP_785194.1
- ProteinModelPortal:   Q88WM6
- SMR:   Q88WM6
- GeneID:   1063615
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_1601
- NMPDR:   fig|220668.1.peg.1328
- HOGENOM:   HBG728416
- OMA:   GMKISET
- ProtClustDB:   PRK00977
- BioCyc:   LPLA220668:LP_1601-MONOMER
- BRENDA:   3.1.11.6
- GO:   GO:0005737
- HAMAP:   MF_00337
- InterPro:   IPR003761
- PIRSF:   PIRSF006488
- ProDom:   PD028235
- TIGRFAMs:   TIGR01280

Pfam domain/function: PF02609 Exonuc_VII_S

EC number: =3.1.11.6

Molecular weight: Translated: 8451; Mature: 8320

Theoretical pI: Translated: 3.67; Mature: 3.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQPTFEQNLSQLETIVNQLEQGDVPLEQALDQFQKGVALSKQLQATLEGAEKTLTKMM
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NENGDEVPFEQADANE
HCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEQPTFEQNLSQLETIVNQLEQGDVPLEQALDQFQKGVALSKQLQATLEGAEKTLTKMM
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NENGDEVPFEQADANE
HCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566