Click here to switch to the map view.

The map label for this gene is sat

Identifier: 28378115

GI number: 28378115

Start: 1262554

End: 1263729

Strand: Direct

Name: sat

Synonym: lp_1378

Alternate gene names: 28378115

Gene position: 1262554-1263729 (Clockwise)

Preceding gene: 28378114

Following gene: 28378116

Centisome position: 38.16

GC content: 45.49

Gene sequence:

>1176_bases
ATGCAAACAGTGTACGGAATTAAAGCTCATGGTGGTAAGTTAGTTAATCTAGAAGATTTTAGTGAAGCAACGCGTCAGGC
TGCTGAGCAGCTGCCAAGTTTAACCATCAATAATTGGAATATCTCAGACTTGGAATTAATTGGGATTGGTGGTTTTAGCC
CCCTGACTGGCTTCATGGTCAGTGATGATTACCATTCAGTGGTCAACACGATGCACTTGAAGAGTGGCGTTATCTGGAGT
GTACCAATTACGCTGGGTGTGTCCCAAGCGGATGCTGATAAGATTGAATTGAATACTAAGATTGCTTTGAAGGGCGCTGA
CGGCGTCATTTATGGCACGATGCAAGTTGAAGATAAGTTTGTTCCGGACAAGCAATTGGAAGCCCAAAACGTCTACAAGA
CCACCGACGAAGCCCATCCAGGTGTTAAACGCTTGTATGCCAATGGTGACGTCTACTTGGGTGGCGCAATTAAATTGTTG
CATAAGCCAGATCATGGTGCTTTTAGTGATTATTATATGGAACCATTAGAAACTCGGAAGATGTTCCATGACCTCGGCTG
GAAGCGGATCGTTGGGTTCCAGACACGGAATCCAATTCATCGGGCGCATGAATATATTCAAAAATTAGCTTTGGAAAACG
TCGATGGGTTATTCTTAAATCCATTGGTTGGTGAGACCAAGGCGGATGATATTCCAGCAGACGTTCGGATGGAAAGCTAT
AAGACGATTCTGAAGTATTACTATCCAGAAGACCGTGTTCGGTTGGTCATTTATCCAGCCGCGATGCGGTATGCTGGTCC
TAAGGAAGCCATCTTACACGCAATCGTTCGTAAAAACTATGGTTGTACTGATTTTATCGTCGGTCGTGACCATGCTGGTG
TGGGTGACTATTACGGGACCTATGAAGCCCAAGAATTAATCACTTCGGTCGAAGATGAGATGGGCATGCACTTCTTCAAA
TTCGATAATTCCTTCTACTGCAAAAAGTGTGGTTCAATGGCAACGCAGAAGACTTGTCCACACGGTGCCGAAGATCACAT
CTCATTAAGCGGGACGAAGGTGCGTAAGATGCTGGCTGATGGTGTTGTACCACCAAAGGAAGTTTCACGTCCCGAAGTTG
CCCGGGTTCTCATCGACGGGTTGAAACGTAAACGTGAACAGCAACAGGAGGTCTAA

Upstream 100 bases:

>100_bases
TTGTGTCGACGTGCGAGTCAGGATGAGCAACAACAAGCCGCATTGAACCATTTTGTAAGTCTTAATTATGATGAAATTTT
AAACGTGAAAGGTGATCAAT

Downstream 100 bases:

>100_bases
GCATGGTAAAATCAGATAATATTACTTGGCATCAATCGCAAGTTAGCAAGGCCGAACGGCAAGCGCTGAACCATCATAAG
AGTGTGGTTTTATGGTTTAC

Product: sulfate adenylyltransferase

Products: NA

Alternate protein names: ATP-sulfurylase; Sulfate adenylate transferase; SAT

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MQTVYGIKAHGGKLVNLEDFSEATRQAAEQLPSLTINNWNISDLELIGIGGFSPLTGFMVSDDYHSVVNTMHLKSGVIWS
VPITLGVSQADADKIELNTKIALKGADGVIYGTMQVEDKFVPDKQLEAQNVYKTTDEAHPGVKRLYANGDVYLGGAIKLL
HKPDHGAFSDYYMEPLETRKMFHDLGWKRIVGFQTRNPIHRAHEYIQKLALENVDGLFLNPLVGETKADDIPADVRMESY
KTILKYYYPEDRVRLVIYPAAMRYAGPKEAILHAIVRKNYGCTDFIVGRDHAGVGDYYGTYEAQELITSVEDEMGMHFFK
FDNSFYCKKCGSMATQKTCPHGAEDHISLSGTKVRKMLADGVVPPKEVSRPEVARVLIDGLKRKREQQQEV

Sequences:

>Translated_391_residues
MQTVYGIKAHGGKLVNLEDFSEATRQAAEQLPSLTINNWNISDLELIGIGGFSPLTGFMVSDDYHSVVNTMHLKSGVIWS
VPITLGVSQADADKIELNTKIALKGADGVIYGTMQVEDKFVPDKQLEAQNVYKTTDEAHPGVKRLYANGDVYLGGAIKLL
HKPDHGAFSDYYMEPLETRKMFHDLGWKRIVGFQTRNPIHRAHEYIQKLALENVDGLFLNPLVGETKADDIPADVRMESY
KTILKYYYPEDRVRLVIYPAAMRYAGPKEAILHAIVRKNYGCTDFIVGRDHAGVGDYYGTYEAQELITSVEDEMGMHFFK
FDNSFYCKKCGSMATQKTCPHGAEDHISLSGTKVRKMLADGVVPPKEVSRPEVARVLIDGLKRKREQQQEV
>Mature_391_residues
MQTVYGIKAHGGKLVNLEDFSEATRQAAEQLPSLTINNWNISDLELIGIGGFSPLTGFMVSDDYHSVVNTMHLKSGVIWS
VPITLGVSQADADKIELNTKIALKGADGVIYGTMQVEDKFVPDKQLEAQNVYKTTDEAHPGVKRLYANGDVYLGGAIKLL
HKPDHGAFSDYYMEPLETRKMFHDLGWKRIVGFQTRNPIHRAHEYIQKLALENVDGLFLNPLVGETKADDIPADVRMESY
KTILKYYYPEDRVRLVIYPAAMRYAGPKEAILHAIVRKNYGCTDFIVGRDHAGVGDYYGTYEAQELITSVEDEMGMHFFK
FDNSFYCKKCGSMATQKTCPHGAEDHISLSGTKVRKMLADGVVPPKEVSRPEVARVLIDGLKRKREQQQEV

Specific function: Unknown

COG id: COG2046

COG function: function code P; ATP sulfurylase (sulfate adenylyltransferase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfate adenylyltransferase family

Homologues:

Organism=Homo sapiens, GI62912492, Length=384, Percent_Identity=28.90625, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI34447231, Length=379, Percent_Identity=29.023746701847, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI46094058, Length=370, Percent_Identity=30, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17542422, Length=391, Percent_Identity=28.6445012787724, Blast_Score=138, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6322469, Length=352, Percent_Identity=38.9204545454545, Blast_Score=241, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24667032, Length=383, Percent_Identity=30.0261096605744, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24667028, Length=383, Percent_Identity=30.0261096605744, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24667036, Length=383, Percent_Identity=30.0261096605744, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI116007838, Length=383, Percent_Identity=30.0261096605744, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24667044, Length=383, Percent_Identity=30.0261096605744, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24667040, Length=383, Percent_Identity=30.0261096605744, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SAT_LACPL (Q88X61)

Other databases:

- EMBL:   AL935256
- RefSeq:   NP_785007.1
- HSSP:   Q12650
- ProteinModelPortal:   Q88X61
- SMR:   Q88X61
- GeneID:   1062563
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_1378
- NMPDR:   fig|220668.1.peg.1141
- HOGENOM:   HBG480761
- OMA:   RMESYEV
- ProtClustDB:   PRK04149
- BioCyc:   LPLA220668:LP_1378-MONOMER
- HAMAP:   MF_00066
- InterPro:   IPR015947
- InterPro:   IPR014729
- InterPro:   IPR020792
- InterPro:   IPR002650
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00339

Pfam domain/function: PF01747 ATP-sulfurylase; SSF88697 PUA-like

EC number: =2.7.7.4

Molecular weight: Translated: 43856; Mature: 43856

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVYGIKAHGGKLVNLEDFSEATRQAAEQLPSLTINNWNISDLELIGIGGFSPLTGFMV
CCCEEEEECCCCEEEEHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEECCCCCCCCEEE
SDDYHSVVNTMHLKSGVIWSVPITLGVSQADADKIELNTKIALKGADGVIYGTMQVEDKF
CCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEEEEEEECCCEEEEEEEEECCCC
VPDKQLEAQNVYKTTDEAHPGVKRLYANGDVYLGGAIKLLHKPDHGAFSDYYMEPLETRK
CCCCCCCHHHHHHCCCCCCCCHHHEEECCCEEECCEEEEEECCCCCCCHHHHHCHHHHHH
MFHDLGWKRIVGFQTRNPIHRAHEYIQKLALENVDGLFLNPLVGETKADDIPADVRMESY
HHHHCCHHEEECCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHH
KTILKYYYPEDRVRLVIYPAAMRYAGPKEAILHAIVRKNYGCTDFIVGRDHAGVGDYYGT
HHHHHHHCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
YEAQELITSVEDEMGMHFFKFDNSFYCKKCGSMATQKTCPHGAEDHISLSGTKVRKMLAD
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCHHHHCCCCCCCCCCEECCHHHHHHHHHH
GVVPPKEVSRPEVARVLIDGLKRKREQQQEV
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQTVYGIKAHGGKLVNLEDFSEATRQAAEQLPSLTINNWNISDLELIGIGGFSPLTGFMV
CCCEEEEECCCCEEEEHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEECCCCCCCCEEE
SDDYHSVVNTMHLKSGVIWSVPITLGVSQADADKIELNTKIALKGADGVIYGTMQVEDKF
CCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEEEEEEECCCEEEEEEEEECCCC
VPDKQLEAQNVYKTTDEAHPGVKRLYANGDVYLGGAIKLLHKPDHGAFSDYYMEPLETRK
CCCCCCCHHHHHHCCCCCCCCHHHEEECCCEEECCEEEEEECCCCCCCHHHHHCHHHHHH
MFHDLGWKRIVGFQTRNPIHRAHEYIQKLALENVDGLFLNPLVGETKADDIPADVRMESY
HHHHCCHHEEECCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHH
KTILKYYYPEDRVRLVIYPAAMRYAGPKEAILHAIVRKNYGCTDFIVGRDHAGVGDYYGT
HHHHHHHCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
YEAQELITSVEDEMGMHFFKFDNSFYCKKCGSMATQKTCPHGAEDHISLSGTKVRKMLAD
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCHHHHCCCCCCCCCCEECCHHHHHHHHHH
GVVPPKEVSRPEVARVLIDGLKRKREQQQEV
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12566566