Click here to switch to the map view.

The map label for this gene is tagD2 [H]

Identifier: 28378016

GI number: 28378016

Start: 1132563

End: 1132961

Strand: Direct

Name: tagD2 [H]

Synonym: lp_1248

Alternate gene names: 28378016

Gene position: 1132563-1132961 (Clockwise)

Preceding gene: 28378015

Following gene: 28378021

Centisome position: 34.23

GC content: 44.86

Gene sequence:

>399_bases
TTGAAGAAAGTAATTACGTATGGGACATTCGATTTGTTGCATAAAGGCCATATTCGGTTGCTTAAGCGTGCACGGGCCTT
GGGCGATCATTTGACCGTTTGCGTCTCGACCGACGAATTCAATGCTGAGAAGGGTAAGCATGCGTACACCTCGTATGAGG
ATCGTAAGTATATTTTGCAAGCCATTCGCTATGTCGATGAAGTGTTACCTGAGAAAAGCTGGGATCAAAAAATCCGGGAT
GTCGTTGATAACGATATTGATATTTTCGTGATGGGTGACGATTGGCGCGGCAAGTTTGATTTTCTAAAAGACTACTGCGA
GGTGGTCTATTTGCCCCGTACTGAAGGCATCTCATCGACGCGTATCAAGCACGATTTAGGGATGCAATCCAAGGATTAA

Upstream 100 bases:

>100_bases
AAGGCGACTAAAGCAGACTTGACGACGACCACTAAATCAAAAAAGTAGTCTGTGCTATAATTGGTGAATTAAGCTTGAAC
GTGGCATAAGGAGTGATTTT

Downstream 100 bases:

>100_bases
CCACTAAGCTAGATGATTTATCAGTCACAAAACACCGCCGTTACCCGCAACTTCAAGCTGCGTAACAGCGGTGTTTTAAT
TAACAGTTATTAGTAAGTCA

Product: glycerol-3-phosphate cytidylyltransferase

Products: NA

Alternate protein names: GCT; Gro-PCT; CDP-glycerol pyrophosphorylase; Teichoic acid biosynthesis protein D [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MKKVITYGTFDLLHKGHIRLLKRARALGDHLTVCVSTDEFNAEKGKHAYTSYEDRKYILQAIRYVDEVLPEKSWDQKIRD
VVDNDIDIFVMGDDWRGKFDFLKDYCEVVYLPRTEGISSTRIKHDLGMQSKD

Sequences:

>Translated_132_residues
MKKVITYGTFDLLHKGHIRLLKRARALGDHLTVCVSTDEFNAEKGKHAYTSYEDRKYILQAIRYVDEVLPEKSWDQKIRD
VVDNDIDIFVMGDDWRGKFDFLKDYCEVVYLPRTEGISSTRIKHDLGMQSKD
>Mature_132_residues
MKKVITYGTFDLLHKGHIRLLKRARALGDHLTVCVSTDEFNAEKGKHAYTSYEDRKYILQAIRYVDEVLPEKSWDQKIRD
VVDNDIDIFVMGDDWRGKFDFLKDYCEVVYLPRTEGISSTRIKHDLGMQSKD

Specific function: Provides activated glycerol phosphate for teichoic acid synthesis, via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF [H]

COG id: COG0615

COG function: function code MI; Cytidylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI296841136, Length=120, Percent_Identity=36.6666666666667, Blast_Score=66, Evalue=7e-12,
Organism=Homo sapiens, GI4505651, Length=120, Percent_Identity=35, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR006409
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.39 [H]

Molecular weight: Translated: 15475; Mature: 15475

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVITYGTFDLLHKGHIRLLKRARALGDHLTVCVSTDEFNAEKGKHAYTSYEDRKYILQ
CCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
AIRYVDEVLPEKSWDQKIRDVVDNDIDIFVMGDDWRGKFDFLKDYCEVVYLPRTEGISST
HHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCHH
RIKHDLGMQSKD
HHHHHCCCCCCC
>Mature Secondary Structure
MKKVITYGTFDLLHKGHIRLLKRARALGDHLTVCVSTDEFNAEKGKHAYTSYEDRKYILQ
CCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
AIRYVDEVLPEKSWDQKIRDVVDNDIDIFVMGDDWRGKFDFLKDYCEVVYLPRTEGISST
HHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCHH
RIKHDLGMQSKD
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 8393871; 9384377; 9182537; 11487587; 10508782 [H]