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The map label for this gene is pts14C [H]

Identifier: 28377941

GI number: 28377941

Start: 1062473

End: 1063780

Strand: Direct

Name: pts14C [H]

Synonym: lp_1164

Alternate gene names: 28377941

Gene position: 1062473-1063780 (Clockwise)

Preceding gene: 28377939

Following gene: 28377942

Centisome position: 32.12

GC content: 48.78

Gene sequence:

>1308_bases
ATGTTAAAGCATGTACAGAACAGCCTATTGACCTTTGAACGGGTCGTTGAGCGGCAACGTTATTGGCGCGCCTTACGTGA
TACGTTGACGCTGCTTTTTCCATTCGCATTAGTTGGGGCGTACGTTAGTTTTATGAACCAGGCAATCTTTCAGCGCAATG
GTTTTTTGAATCATATTTATTATCTCAGTCACTGGCTGCCGGGGTTTAAACATTTGGCAACTTACACGACGATGCTTAAT
CTGAGTATCAACGGCATTCTTGCCGTGATTGCGGCTTTTTCAGCCGCTAATTTTGTCGCGCGGAGTGCCCAGCGTGATAA
TCTGTTAGCGGGATTGACGGCGGCAATTAGTTTTATCATGCTTAATATCAATTATAATTTTTTTAGTACCCAGGGTCAGC
CTGCTGGCAGTCGGTTTTTAGAAGATAATTTGGGAACTCAGGGCATCTTCCTCGCACTATTGGTGGGCCTGTTGACTGGT
TGGTTGTTCAGTCATTTGACACGGTATCCACACATCCACCAGGAGATCGAGACCCAGACGCACTTGCTAGCGCGGGCACA
CGCGAACTGGTTACCGATAGTCGCTGCTTTGCTGGTGTTCAGTGCCATCGGGTATGGTGTTAGTTTTGTCAGTAAAGGGG
GATTAAACGGCCTGTTTTACGCGGTCTTCACCTTACCATTCAGTAATCCGGGGGCGTCGCTACTAGCGATAATTGGCGTG
GCATCGCTCAGCAATTTATACTGGTTAATCGGGATTATCGGTCCGGTTGACTTTAGTGGTAACAGTACTACAAGTACGGT
TCAAAATTTGGAATATGCGTTGCAACACGGTTCGGCGTGGGGCGCGCCAAATCCAGTAACGCTCCATACGTTATTTGATG
CGTTTGCGAACGTAGGTGGTCCCGGAATGACGTTAGCGTTATTGATTGCAATTTTGTGGCGTTCACGTAACCGTAATTAT
CGAACGGTGGCCAAGACCAGTGCCTTGCCAGTACTGTTTAATATCAACCAACCGTTGCTCGTCGGCTTACCGATTGCTTA
TAGTCCGATTTTAGCGATTCCGTTTCTATTAGCGCCACTGGCTAGCATGGTCATCACGTGGTGCGCGTTGAAGCTTCAAT
GGATGCCACCGGTCGTTTATCCGGTTGGTAGAACGATGCCGGGCTTCTTGACCGGTTGGCTGGGAACTGGTGGCGACTGG
CGGGCCTTCATCGTTAGTCTGATCAATATAGCGGTAGCCACAGCAGTCTACTTGCCATTTGTCCTATTGGCAAACCAGGT
TGAGGAGGAGGCGCAGGCGGATGCTTAA

Upstream 100 bases:

>100_bases
TAATGGATTAGTGTCGGGCAATAAAATTAAACGCACCTAGTGGGCAAGGCCGATGAACTAGCGTATATTATAGACAGTAA
ATTTCTTTTGGGGGTTAGGT

Downstream 100 bases:

>100_bases
ACGATATTGGTGGCGGTGGCTTCTTGGAATCGGTTTGTTAGTCGGGATCTGTTGGCCGGCCTACACGTGGAGTCAAGCGA
ATATCAAGACGCTGAAAAAC

Product: cellobiose PTS, EIIC

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Chb; PTS system N,N'-diacetylchitobiose-specific EIIC component [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MLKHVQNSLLTFERVVERQRYWRALRDTLTLLFPFALVGAYVSFMNQAIFQRNGFLNHIYYLSHWLPGFKHLATYTTMLN
LSINGILAVIAAFSAANFVARSAQRDNLLAGLTAAISFIMLNINYNFFSTQGQPAGSRFLEDNLGTQGIFLALLVGLLTG
WLFSHLTRYPHIHQEIETQTHLLARAHANWLPIVAALLVFSAIGYGVSFVSKGGLNGLFYAVFTLPFSNPGASLLAIIGV
ASLSNLYWLIGIIGPVDFSGNSTTSTVQNLEYALQHGSAWGAPNPVTLHTLFDAFANVGGPGMTLALLIAILWRSRNRNY
RTVAKTSALPVLFNINQPLLVGLPIAYSPILAIPFLLAPLASMVITWCALKLQWMPPVVYPVGRTMPGFLTGWLGTGGDW
RAFIVSLINIAVATAVYLPFVLLANQVEEEAQADA

Sequences:

>Translated_435_residues
MLKHVQNSLLTFERVVERQRYWRALRDTLTLLFPFALVGAYVSFMNQAIFQRNGFLNHIYYLSHWLPGFKHLATYTTMLN
LSINGILAVIAAFSAANFVARSAQRDNLLAGLTAAISFIMLNINYNFFSTQGQPAGSRFLEDNLGTQGIFLALLVGLLTG
WLFSHLTRYPHIHQEIETQTHLLARAHANWLPIVAALLVFSAIGYGVSFVSKGGLNGLFYAVFTLPFSNPGASLLAIIGV
ASLSNLYWLIGIIGPVDFSGNSTTSTVQNLEYALQHGSAWGAPNPVTLHTLFDAFANVGGPGMTLALLIAILWRSRNRNY
RTVAKTSALPVLFNINQPLLVGLPIAYSPILAIPFLLAPLASMVITWCALKLQWMPPVVYPVGRTMPGFLTGWLGTGGDW
RAFIVSLINIAVATAVYLPFVLLANQVEEEAQADA
>Mature_435_residues
MLKHVQNSLLTFERVVERQRYWRALRDTLTLLFPFALVGAYVSFMNQAIFQRNGFLNHIYYLSHWLPGFKHLATYTTMLN
LSINGILAVIAAFSAANFVARSAQRDNLLAGLTAAISFIMLNINYNFFSTQGQPAGSRFLEDNLGTQGIFLALLVGLLTG
WLFSHLTRYPHIHQEIETQTHLLARAHANWLPIVAALLVFSAIGYGVSFVSKGGLNGLFYAVFTLPFSNPGASLLAIIGV
ASLSNLYWLIGIIGPVDFSGNSTTSTVQNLEYALQHGSAWGAPNPVTLHTLFDAFANVGGPGMTLALLIAILWRSRNRNY
RTVAKTSALPVLFNINQPLLVGLPIAYSPILAIPFLLAPLASMVITWCALKLQWMPPVVYPVGRTMPGFLTGWLGTGGDW
RAFIVSLINIAVATAVYLPFVLLANQVEEEAQADA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=456, Percent_Identity=26.9736842105263, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 47684; Mature: 47684

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKHVQNSLLTFERVVERQRYWRALRDTLTLLFPFALVGAYVSFMNQAIFQRNGFLNHIY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YLSHWLPGFKHLATYTTMLNLSINGILAVIAAFSAANFVARSAQRDNLLAGLTAAISFIM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LNINYNFFSTQGQPAGSRFLEDNLGTQGIFLALLVGLLTGWLFSHLTRYPHIHQEIETQT
EEECCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HLLARAHANWLPIVAALLVFSAIGYGVSFVSKGGLNGLFYAVFTLPFSNPGASLLAIIGV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHEEECCCCCCHHHHHHHHH
ASLSNLYWLIGIIGPVDFSGNSTTSTVQNLEYALQHGSAWGAPNPVTLHTLFDAFANVGG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
PGMTLALLIAILWRSRNRNYRTVAKTSALPVLFNINQPLLVGLPIAYSPILAIPFLLAPL
CHHHHHHHHHHHHHCCCCCEEEHHHCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHH
ASMVITWCALKLQWMPPVVYPVGRTMPGFLTGWLGTGGDWRAFIVSLINIAVATAVYLPF
HHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VLLANQVEEEAQADA
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKHVQNSLLTFERVVERQRYWRALRDTLTLLFPFALVGAYVSFMNQAIFQRNGFLNHIY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YLSHWLPGFKHLATYTTMLNLSINGILAVIAAFSAANFVARSAQRDNLLAGLTAAISFIM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LNINYNFFSTQGQPAGSRFLEDNLGTQGIFLALLVGLLTGWLFSHLTRYPHIHQEIETQT
EEECCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HLLARAHANWLPIVAALLVFSAIGYGVSFVSKGGLNGLFYAVFTLPFSNPGASLLAIIGV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHEEECCCCCCHHHHHHHHH
ASLSNLYWLIGIIGPVDFSGNSTTSTVQNLEYALQHGSAWGAPNPVTLHTLFDAFANVGG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
PGMTLALLIAILWRSRNRNYRTVAKTSALPVLFNINQPLLVGLPIAYSPILAIPFLLAPL
CHHHHHHHHHHHHHCCCCCEEEHHHCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHH
ASMVITWCALKLQWMPPVVYPVGRTMPGFLTGWLGTGGDWRAFIVSLINIAVATAVYLPF
HHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VLLANQVEEEAQADA
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 2092358; 9405618; 10913117 [H]