Click here to switch to the map view.

The map label for this gene is citE [H]

Identifier: 28377896

GI number: 28377896

Start: 1005719

End: 1006633

Strand: Direct

Name: citE [H]

Synonym: lp_1108

Alternate gene names: 28377896

Gene position: 1005719-1006633 (Clockwise)

Preceding gene: 28377895

Following gene: 28377897

Centisome position: 30.4

GC content: 48.42

Gene sequence:

>915_bases
ATGGCTGAAAATGAAGAACGCTTACGGCGGACAATGATGTTTGTACCTGGTAATAATCCAGCCATGGTAAAGGATGCCGG
GATTTACGGTGCAGACTCGATCATGTTTGACTTGGAAGATGCCGTCTCAATGGCTGAAAAGGATGCGGCCCGGGTGCTGG
TTTACGAAGCGTTAAAAACGCAAGATTATGGCAACGCTGAATTGGTCGTTCGAATCAATGGTTTGGATACCAAGTATTAC
GCTGATGATGTCAAAGCAATGGTCAAGGCTGGCATTGATGTTATCCGTTTGCCAAAAGTCGAATCGGCTACCATGATCCA
AACGTTGGAAAAGGATGTCGCGGCAGCTGAAGCTGAATTTAAGATACCAGTTGGCACGACTCATTTGATGGCTGCAATTG
AAAGCGCTAAGGGCGTGCTTAATGCCCCGGCAATCGCGGCAGCCTCGGATCGAATGATTGGGATCGCCTTGTCAGCAGAA
GATTATACGACGGACATGAAGACCCACCGTTATCCTGATGGCGCGGAACTGGAATTTGCCCGTAACATGGTGCTTCATGC
TGCTCGTGCCGCTGGAATCGCCGCGTTCGATACGGTCTTTACAAACATGGCCGATCCCGATGGCTTCTACCGTGAGACGC
GGCATATTCATCAATTAGGATTTGACGGTAAATCATTGGTCAACCCTCGACAGATTGCAATGGTCAATTCAGTCTATGAA
CCAACCAAGGATGAAGTTATTAAGGCCCAAAAAGTCATCGCCGCGATTGAGGAAGCCCGGATCAAGGGTTCTGGTGTTAT
TTCCATGAATGGCCAAATGGTAGACCGGCCCGTTGTTTTGCGGGCTCAACGTGTGATGAGCTTAGCCAAAGTTTCCAACT
TACTCGACGAGGAGGGCAATTACATTGAAAAATAG

Upstream 100 bases:

>100_bases
CTGTTGATAAAGGGGCGTTGGACTGCGTCATTAAAGCGCGGACCATTACGGCAGCACAACGGGCGTTAGAAACCACGACA
CCAGCATGGGAGGTATTATA

Downstream 100 bases:

>100_bases
TGTAGACCGCGAATTACCAGCAGAATTAATGACGAAGTTAAATTACCAAGGTTTTGAGTCAACCGAAATCGGACATCCTG
AAATTCAACGGGTGGCCCCC

Product: citrate lyase, beta chain

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MAENEERLRRTMMFVPGNNPAMVKDAGIYGADSIMFDLEDAVSMAEKDAARVLVYEALKTQDYGNAELVVRINGLDTKYY
ADDVKAMVKAGIDVIRLPKVESATMIQTLEKDVAAAEAEFKIPVGTTHLMAAIESAKGVLNAPAIAAASDRMIGIALSAE
DYTTDMKTHRYPDGAELEFARNMVLHAARAAGIAAFDTVFTNMADPDGFYRETRHIHQLGFDGKSLVNPRQIAMVNSVYE
PTKDEVIKAQKVIAAIEEARIKGSGVISMNGQMVDRPVVLRAQRVMSLAKVSNLLDEEGNYIEK

Sequences:

>Translated_304_residues
MAENEERLRRTMMFVPGNNPAMVKDAGIYGADSIMFDLEDAVSMAEKDAARVLVYEALKTQDYGNAELVVRINGLDTKYY
ADDVKAMVKAGIDVIRLPKVESATMIQTLEKDVAAAEAEFKIPVGTTHLMAAIESAKGVLNAPAIAAASDRMIGIALSAE
DYTTDMKTHRYPDGAELEFARNMVLHAARAAGIAAFDTVFTNMADPDGFYRETRHIHQLGFDGKSLVNPRQIAMVNSVYE
PTKDEVIKAQKVIAAIEEARIKGSGVISMNGQMVDRPVVLRAQRVMSLAKVSNLLDEEGNYIEK
>Mature_303_residues
AENEERLRRTMMFVPGNNPAMVKDAGIYGADSIMFDLEDAVSMAEKDAARVLVYEALKTQDYGNAELVVRINGLDTKYYA
DDVKAMVKAGIDVIRLPKVESATMIQTLEKDVAAAEAEFKIPVGTTHLMAAIESAKGVLNAPAIAAASDRMIGIALSAED
YTTDMKTHRYPDGAELEFARNMVLHAARAAGIAAFDTVFTNMADPDGFYRETRHIHQLGFDGKSLVNPRQIAMVNSVYEP
TKDEVIKAQKVIAAIEEARIKGSGVISMNGQMVDRPVVLRAQRVMSLAKVSNLLDEEGNYIEK

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=291, Percent_Identity=27.8350515463918, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI87081764, Length=297, Percent_Identity=48.8215488215488, Blast_Score=282, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17557458, Length=305, Percent_Identity=28.5245901639344, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 33264; Mature: 33132

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENEERLRRTMMFVPGNNPAMVKDAGIYGADSIMFDLEDAVSMAEKDAARVLVYEALKT
CCCCHHHHHHEEEEECCCCCCEEEECCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHC
QDYGNAELVVRINGLDTKYYADDVKAMVKAGIDVIRLPKVESATMIQTLEKDVAAAEAEF
CCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCEE
KIPVGTTHLMAAIESAKGVLNAPAIAAASDRMIGIALSAEDYTTDMKTHRYPDGAELEFA
ECCCCHHHHHHHHHHHCCCCCCCCCEECCCCEEEEEEECCCHHCCCHHCCCCCCCHHHHH
RNMVLHAARAAGIAAFDTVFTNMADPDGFYRETRHIHQLGFDGKSLVNPRQIAMVNSVYE
HHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCC
PTKDEVIKAQKVIAAIEEARIKGSGVISMNGQMVDRPVVLRAQRVMSLAKVSNLLDEEGN
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHCCCC
YIEK
CCCC
>Mature Secondary Structure 
AENEERLRRTMMFVPGNNPAMVKDAGIYGADSIMFDLEDAVSMAEKDAARVLVYEALKT
CCCHHHHHHEEEEECCCCCCEEEECCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHC
QDYGNAELVVRINGLDTKYYADDVKAMVKAGIDVIRLPKVESATMIQTLEKDVAAAEAEF
CCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCEE
KIPVGTTHLMAAIESAKGVLNAPAIAAASDRMIGIALSAEDYTTDMKTHRYPDGAELEFA
ECCCCHHHHHHHHHHHCCCCCCCCCEECCCCEEEEEEECCCHHCCCHHCCCCCCCHHHHH
RNMVLHAARAAGIAAFDTVFTNMADPDGFYRETRHIHQLGFDGKSLVNPRQIAMVNSVYE
HHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCC
PTKDEVIKAQKVIAAIEEARIKGSGVISMNGQMVDRPVVLRAQRVMSLAKVSNLLDEEGN
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHCCCC
YIEK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457870 [H]