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The map label for this gene is mtsA [H]

Identifier: 28377888

GI number: 28377888

Start: 997831

End: 998772

Strand: Direct

Name: mtsA [H]

Synonym: lp_1097

Alternate gene names: 28377888

Gene position: 997831-998772 (Clockwise)

Preceding gene: 28377887

Following gene: 28377890

Centisome position: 30.16

GC content: 46.92

Gene sequence:

>942_bases
ATGAAAACGAAATTAATTGCACTGATTGGAGTCATCGCGATGGTTACCGGGATGGCAGTATTTCTGAATCAACGCCAGCA
AAGTGCCAAAGCGACGACCACTAGTGCCAAAATCCGGGTCGTAAGTACGAACTCGATTCTAGATGATATGGTGAAAAATG
TGGGTGGGCAGTACGTCCAAAATTACAGTATTGTGAAGCGCGGCACTGACCCGCATGAGTATGAACCACGGCCCACTGAT
ATTGCGGCAACTGCCGAAGCTGACGTGATTTTTTATAATGGCTTAAACCTTGAAACTGGCGGTAATGGCTGGTTTAAAAA
GTTAGTGACGGCTTCCAAAAAGGACTTTGACCACGATGTTTTTGCGGCCAGTAAGGGAATTAAGGTCAAATATTTAACGA
CGAACGTTAATGAGCCGGACCCCCATGCTTGGTTAGATCTCGCCAACGGGATTCAATATGTCAAGAACATCAACCGGACG
TTGCAGGCCAAGGATCCTAAGCACGCCGCTGTTTATCAAAAGAATACGGATCGCTACGTGGCAAAACTAACAAAACTGCA
TGAGAGCGCTCAAACCAAATTCAAGCAGATCCCGACGAGTCAACGATTATTAGTGACATCCGAAGGCGCCTTTAAGTATT
TCTCGGCGGCCTACCATGTGCCCGCTGCTTATATTTGGGAAGTGAATACGGAATCGCAAGGCACGCCAGCTCAGATGCGG
ACGGCGTTGAAGAAAATTGAAGGAACCCAGGTTCGAAGTTTGTTTGTCGAATCATCCGTATCACCGAAATCGATGAATAA
GCTTTCACAGGAGACGGGAATCCCCGTTGCTAGTACGATTTTTACCGATTCGCTGGCAGCTAAAGGCAAGCCGGGTGATA
CGTACTACTCAATGTTGAAGTGGAATCTTGATAAGATTTATGCTGGGCTGACTCGGTCGTAG

Upstream 100 bases:

>100_bases
TAGCGGCTATTTTCTTCGGTATTTCTTTCATCATCTCACCTAAGCAGGCCTTGTTGCCGACGCTTTGGAAAGGGCAAGCA
GCAGCGCGACGGGTGACAGC

Downstream 100 bases:

>100_bases
TACTTGGGCCTATAATTCGGTTGTGTTGATGTCATGTGATATAAGTTTGTTCTAAAAAGGACCGTGGAAGTTAAATCTTC
CACGGTCCTTTCTTTATTTT

Product: manganese ABC transporter, substrate binding protein

Products: NA

Alternate protein names: Pneumococcal surface adhesin A [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKTKLIALIGVIAMVTGMAVFLNQRQQSAKATTTSAKIRVVSTNSILDDMVKNVGGQYVQNYSIVKRGTDPHEYEPRPTD
IAATAEADVIFYNGLNLETGGNGWFKKLVTASKKDFDHDVFAASKGIKVKYLTTNVNEPDPHAWLDLANGIQYVKNINRT
LQAKDPKHAAVYQKNTDRYVAKLTKLHESAQTKFKQIPTSQRLLVTSEGAFKYFSAAYHVPAAYIWEVNTESQGTPAQMR
TALKKIEGTQVRSLFVESSVSPKSMNKLSQETGIPVASTIFTDSLAAKGKPGDTYYSMLKWNLDKIYAGLTRS

Sequences:

>Translated_313_residues
MKTKLIALIGVIAMVTGMAVFLNQRQQSAKATTTSAKIRVVSTNSILDDMVKNVGGQYVQNYSIVKRGTDPHEYEPRPTD
IAATAEADVIFYNGLNLETGGNGWFKKLVTASKKDFDHDVFAASKGIKVKYLTTNVNEPDPHAWLDLANGIQYVKNINRT
LQAKDPKHAAVYQKNTDRYVAKLTKLHESAQTKFKQIPTSQRLLVTSEGAFKYFSAAYHVPAAYIWEVNTESQGTPAQMR
TALKKIEGTQVRSLFVESSVSPKSMNKLSQETGIPVASTIFTDSLAAKGKPGDTYYSMLKWNLDKIYAGLTRS
>Mature_313_residues
MKTKLIALIGVIAMVTGMAVFLNQRQQSAKATTTSAKIRVVSTNSILDDMVKNVGGQYVQNYSIVKRGTDPHEYEPRPTD
IAATAEADVIFYNGLNLETGGNGWFKKLVTASKKDFDHDVFAASKGIKVKYLTTNVNEPDPHAWLDLANGIQYVKNINRT
LQAKDPKHAAVYQKNTDRYVAKLTKLHESAQTKFKQIPTSQRLLVTSEGAFKYFSAAYHVPAAYIWEVNTESQGTPAQMR
TALKKIEGTQVRSLFVESSVSPKSMNKLSQETGIPVASTIFTDSLAAKGKPGDTYYSMLKWNLDKIYAGLTRS

Specific function: Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 34626; Mature: 34626

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKLIALIGVIAMVTGMAVFLNQRQQSAKATTTSAKIRVVSTNSILDDMVKNVGGQYVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHCCHHHHH
NYSIVKRGTDPHEYEPRPTDIAATAEADVIFYNGLNLETGGNGWFKKLVTASKKDFDHDV
CCHHEECCCCCCCCCCCCCCEEEECCCCEEEEECEEECCCCCHHHHHHHHHCCCCCCCHH
FAASKGIKVKYLTTNVNEPDPHAWLDLANGIQYVKNINRTLQAKDPKHAAVYQKNTDRYV
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHH
AKLTKLHESAQTKFKQIPTSQRLLVTSEGAFKYFSAAYHVPAAYIWEVNTESQGTPAQMR
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHH
TALKKIEGTQVRSLFVESSVSPKSMNKLSQETGIPVASTIFTDSLAAKGKPGDTYYSMLK
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
WNLDKIYAGLTRS
HCHHHHHHCCCCC
>Mature Secondary Structure
MKTKLIALIGVIAMVTGMAVFLNQRQQSAKATTTSAKIRVVSTNSILDDMVKNVGGQYVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHCCHHHHH
NYSIVKRGTDPHEYEPRPTDIAATAEADVIFYNGLNLETGGNGWFKKLVTASKKDFDHDV
CCHHEECCCCCCCCCCCCCCEEEECCCCEEEEECEEECCCCCHHHHHHHHHCCCCCCCHH
FAASKGIKVKYLTTNVNEPDPHAWLDLANGIQYVKNINRTLQAKDPKHAAVYQKNTDRYV
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHH
AKLTKLHESAQTKFKQIPTSQRLLVTSEGAFKYFSAAYHVPAAYIWEVNTESQGTPAQMR
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHH
TALKKIEGTQVRSLFVESSVSPKSMNKLSQETGIPVASTIFTDSLAAKGKPGDTYYSMLK
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
WNLDKIYAGLTRS
HCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8945574; 9767595; 11463916; 9379902 [H]