Click here to switch to the map view.

The map label for this gene is citG

Identifier: 28377885

GI number: 28377885

Start: 995052

End: 995894

Strand: Direct

Name: citG

Synonym: lp_1093

Alternate gene names: 28377885

Gene position: 995052-995894 (Clockwise)

Preceding gene: 28377879

Following gene: 28377886

Centisome position: 30.08

GC content: 50.42

Gene sequence:

>843_bases
GTGGATACGAAGATAATTGTCAATCATGCGCTACGAGCGCTTTTATACGAAGTGACGGTCAACCCTAAGCCCGGGCTGGT
CGACCCGTTGTCGGCGGGTCCCCATCCAGACATGAACGCTTTTATGTTTATTGATAGTGCTTTGAGTCTAGCCCCCTACT
TTAATGCTTGTGCAGCGGCGGGCGTCGCGTATACGGCTGTCGATTTGACGGGTTTGTTCAAGCAAATTCGGGGCATTGGT
GTTCAAGCGGAACAAACCATGTTTGCGGCGACCAAGGGCGTGAATACCCATAAAGGGGCGGTGTTCTCACTGGGCGTGCT
AGTGACAGCGGCGGCGTATCAGTTGCAGCACCCCGACGTCGACTTAGCAACGATTGTGCGCACGATGCTGGCGGGGTTAA
CGGCAAATGATTTTAATGATTTAAACACGAAGGATCCAACGACCTTAACTGCTGGAGAACGTCAATACTTAACATATGGC
ATCAAGGGAATTCGTGGTGAAGCCGAGGCGGGTTATCCGACCGTGATGCAAGTGGCACTACCCGCATTGAGACGTAGTCG
TGGCACGATTAATCAGCGGTTATTAGACACACTGATGGCGATTGTCCAGGCGACGGTCGATACCAATCTGGTAAAACGGG
CACACGACCCGCACGTCATTGACTGGGTCCACGACCAAGCACACCGCTACTTCGATTTAGGGGGAAGCCGCAGTGAAGCT
GGAATGGCGTTTTTACGCGAATTGAATCAGATTTTTGTCGACCATAACTATAGTTTAGGTGGCTCGGCCGATTTGTTGAT
TTTGACGATTTTTATTGGATTGCAGACAGATATATTAGCTTAA

Upstream 100 bases:

>100_bases
AATGGTAACTGAATGTTGGTTGTGGTCACGCTTAATCAAGACTGAAAGTGACCCAGGCACATCATCGTTGTTAGACTAAG
GATGAAATGGTGGAGAAATA

Downstream 100 bases:

>100_bases
TAATGAGTGTCGTGATTGTAGGTGACGACACTTTTTTAATACCAAATATTAATGGAAATTAAATGACGATTGCAATGCTT
AGTTGATGAGTGGTCAGTGC

Product: triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MDTKIIVNHALRALLYEVTVNPKPGLVDPLSAGPHPDMNAFMFIDSALSLAPYFNACAAAGVAYTAVDLTGLFKQIRGIG
VQAEQTMFAATKGVNTHKGAVFSLGVLVTAAAYQLQHPDVDLATIVRTMLAGLTANDFNDLNTKDPTTLTAGERQYLTYG
IKGIRGEAEAGYPTVMQVALPALRRSRGTINQRLLDTLMAIVQATVDTNLVKRAHDPHVIDWVHDQAHRYFDLGGSRSEA
GMAFLRELNQIFVDHNYSLGGSADLLILTIFIGLQTDILA

Sequences:

>Translated_280_residues
MDTKIIVNHALRALLYEVTVNPKPGLVDPLSAGPHPDMNAFMFIDSALSLAPYFNACAAAGVAYTAVDLTGLFKQIRGIG
VQAEQTMFAATKGVNTHKGAVFSLGVLVTAAAYQLQHPDVDLATIVRTMLAGLTANDFNDLNTKDPTTLTAGERQYLTYG
IKGIRGEAEAGYPTVMQVALPALRRSRGTINQRLLDTLMAIVQATVDTNLVKRAHDPHVIDWVHDQAHRYFDLGGSRSEA
GMAFLRELNQIFVDHNYSLGGSADLLILTIFIGLQTDILA
>Mature_280_residues
MDTKIIVNHALRALLYEVTVNPKPGLVDPLSAGPHPDMNAFMFIDSALSLAPYFNACAAAGVAYTAVDLTGLFKQIRGIG
VQAEQTMFAATKGVNTHKGAVFSLGVLVTAAAYQLQHPDVDLATIVRTMLAGLTANDFNDLNTKDPTTLTAGERQYLTYG
IKGIRGEAEAGYPTVMQVALPALRRSRGTINQRLLDTLMAIVQATVDTNLVKRAHDPHVIDWVHDQAHRYFDLGGSRSEA
GMAFLRELNQIFVDHNYSLGGSADLLILTIFIGLQTDILA

Specific function: Catalyzes The Formation Of 2-(5''-Triphosphoribosyl)-3'- Dephosphocoenzyme-A, The Precursor Of The Prosthetic Group Of The Holo-Acyl Carrier Protein (Gamma Chain) Of Citrate Lyase, From ATP And Dephospho-CoA. [C]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family

Homologues:

Organism=Escherichia coli, GI1786830, Length=293, Percent_Identity=39.2491467576792, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CITG_LACPL (Q88XT4)

Other databases:

- EMBL:   AL935255
- RefSeq:   NP_784777.1
- GeneID:   1063360
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_1093
- NMPDR:   fig|220668.1.peg.911
- HOGENOM:   HBG305005
- OMA:   LMHASAL
- ProtClustDB:   PRK01237
- BioCyc:   LPLA220668:LP_1093-MONOMER
- BRENDA:   2.7.8.25
- GO:   GO:0016310
- HAMAP:   MF_00397
- InterPro:   IPR002736
- InterPro:   IPR017551
- TIGRFAMs:   TIGR03125

Pfam domain/function: PF01874 CitG

EC number: =2.7.8.25

Molecular weight: Translated: 30279; Mature: 30279

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKIIVNHALRALLYEVTVNPKPGLVDPLSAGPHPDMNAFMFIDSALSLAPYFNACAAA
CCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
GVAYTAVDLTGLFKQIRGIGVQAEQTMFAATKGVNTHKGAVFSLGVLVTAAAYQLQHPDV
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
DLATIVRTMLAGLTANDFNDLNTKDPTTLTAGERQYLTYGIKGIRGEAEAGYPTVMQVAL
CHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHH
PALRRSRGTINQRLLDTLMAIVQATVDTNLVKRAHDPHVIDWVHDQAHRYFDLGGSRSEA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCHH
GMAFLRELNQIFVDHNYSLGGSADLLILTIFIGLQTDILA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTKIIVNHALRALLYEVTVNPKPGLVDPLSAGPHPDMNAFMFIDSALSLAPYFNACAAA
CCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
GVAYTAVDLTGLFKQIRGIGVQAEQTMFAATKGVNTHKGAVFSLGVLVTAAAYQLQHPDV
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
DLATIVRTMLAGLTANDFNDLNTKDPTTLTAGERQYLTYGIKGIRGEAEAGYPTVMQVAL
CHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHH
PALRRSRGTINQRLLDTLMAIVQATVDTNLVKRAHDPHVIDWVHDQAHRYFDLGGSRSEA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCHH
GMAFLRELNQIFVDHNYSLGGSADLLILTIFIGLQTDILA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566