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The map label for this gene is aroA [H]

Identifier: 28377878

GI number: 28377878

Start: 987562

End: 988557

Strand: Direct

Name: aroA [H]

Synonym: lp_1085

Alternate gene names: 28377878

Gene position: 987562-988557 (Clockwise)

Preceding gene: 28377877

Following gene: 28377879

Centisome position: 29.85

GC content: 50.3

Gene sequence:

>996_bases
ATGATTATTATATTAAAACCAGCAACCGCTACGGCTATGCAGGCAAAGTTAGTGAGTCAATTTGGTGCGGATCACGAGAT
CTTCACGCACAATAATCGAATTGCAATTCAAGGATTGCGTCCAGAAGCACTTCCCGCGGATGTGCAAGCAGCCAGTGAAT
CAATCTTGACGGCAGTTCCCGCAGCGGTCCAAAGCAGCCGTCTCTTTCACCCAGAAGATACGATTATTAAGACGCCACAC
AGTGTGATTGGCGGTAATCAATTCGTCATGATGGCTGGCCCGTGTTCAGTCGAAAGCGCTGAACACGTGGACCAGATGGC
CGCGGTTGCCAAGCAGGGTGGTGCGACGATTGTTCGTGGCGGAGCATTCAAGCCACGGACGTCACCTTACAGCTTCCAAG
GCCTCGGGGAGACGGGACTCCAATACTTACGGACGGCGGCTGATAAACATGGCCTTGATATGATTACCGAAGTGATGGAT
GATGAACACGTGGCGATGGTGGCGAAATACACGGATATTTTTCAAATTGGTGCACGCAATATGCAAAATTTCTCGTTGCT
TAAAGCCGTTGGACAGACCCAAATTCCGGTTGCATTAAAGCGAGGAATGTCGGCAACAATCGACGATGTGCTCAATGCAG
CTGAATACATTGCAGCTGGTGGTAATCATCAGATCATGCTTTTGGAGCGGGGAATTCGAACGTTTGATAATAAGTACACA
CGCAACACGTTTGACTTAGGTGCAGTGCCAGTCTTGCAATCGTTGACACATTACCCAGTCATCGTTGATCCGAGTCACGC
GGTCGGTACCTGGGAACTCGTGACCCCGATGGCGATGGCAGGTGTAGCAGCTGGCGCCAGTGGCATGATCGTTGAAATTC
ATGACCAGCCAACGCAAGCTTTATCCGATGGGCCGCAAGCGTTAAAACCCGCGACGTACTTAAAAATGGCGCAACAGGCT
TTCCAGTTACATGATCTGATGCAAACGTGGGCGTAG

Upstream 100 bases:

>100_bases
GTCCGCCAAGATATGTTAGCCAGTATTCAAGCGACTCCGCCGATTACGGCGCAGGCTTAGGCCTTAACTTTTGAGAATTG
ATTAGTAGGAGGAAATTATT

Downstream 100 bases:

>100_bases
GATGTGCCTATGACAAACATTGAAGTCAAGACGCGAGTTAAACAGTATCAGATCAAGATCATGATTAACAGTTTACATCA
CCTAGGAACATTGGTAACTA

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MIIILKPATATAMQAKLVSQFGADHEIFTHNNRIAIQGLRPEALPADVQAASESILTAVPAAVQSSRLFHPEDTIIKTPH
SVIGGNQFVMMAGPCSVESAEHVDQMAAVAKQGGATIVRGGAFKPRTSPYSFQGLGETGLQYLRTAADKHGLDMITEVMD
DEHVAMVAKYTDIFQIGARNMQNFSLLKAVGQTQIPVALKRGMSATIDDVLNAAEYIAAGGNHQIMLLERGIRTFDNKYT
RNTFDLGAVPVLQSLTHYPVIVDPSHAVGTWELVTPMAMAGVAAGASGMIVEIHDQPTQALSDGPQALKPATYLKMAQQA
FQLHDLMQTWA

Sequences:

>Translated_331_residues
MIIILKPATATAMQAKLVSQFGADHEIFTHNNRIAIQGLRPEALPADVQAASESILTAVPAAVQSSRLFHPEDTIIKTPH
SVIGGNQFVMMAGPCSVESAEHVDQMAAVAKQGGATIVRGGAFKPRTSPYSFQGLGETGLQYLRTAADKHGLDMITEVMD
DEHVAMVAKYTDIFQIGARNMQNFSLLKAVGQTQIPVALKRGMSATIDDVLNAAEYIAAGGNHQIMLLERGIRTFDNKYT
RNTFDLGAVPVLQSLTHYPVIVDPSHAVGTWELVTPMAMAGVAAGASGMIVEIHDQPTQALSDGPQALKPATYLKMAQQA
FQLHDLMQTWA
>Mature_331_residues
MIIILKPATATAMQAKLVSQFGADHEIFTHNNRIAIQGLRPEALPADVQAASESILTAVPAAVQSSRLFHPEDTIIKTPH
SVIGGNQFVMMAGPCSVESAEHVDQMAAVAKQGGATIVRGGAFKPRTSPYSFQGLGETGLQYLRTAADKHGLDMITEVMD
DEHVAMVAKYTDIFQIGARNMQNFSLLKAVGQTQIPVALKRGMSATIDDVLNAAEYIAAGGNHQIMLLERGIRTFDNKYT
RNTFDLGAVPVLQSLTHYPVIVDPSHAVGTWELVTPMAMAGVAAGASGMIVEIHDQPTQALSDGPQALKPATYLKMAQQA
FQLHDLMQTWA

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=262, Percent_Identity=24.8091603053435, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 35557; Mature: 35557

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIILKPATATAMQAKLVSQFGADHEIFTHNNRIAIQGLRPEALPADVQAASESILTAVP
CEEEEECCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
AAVQSSRLFHPEDTIIKTPHSVIGGNQFVMMAGPCSVESAEHVDQMAAVAKQGGATIVRG
HHHHHCCCCCCCCCEEECCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEC
GAFKPRTSPYSFQGLGETGLQYLRTAADKHGLDMITEVMDDEHVAMVAKYTDIFQIGARN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
MQNFSLLKAVGQTQIPVALKRGMSATIDDVLNAAEYIAAGGNHQIMLLERGIRTFDNKYT
CHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHCCCCC
RNTFDLGAVPVLQSLTHYPVIVDPSHAVGTWELVTPMAMAGVAAGASGMIVEIHDQPTQA
CCCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHH
LSDGPQALKPATYLKMAQQAFQLHDLMQTWA
HCCCCHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIILKPATATAMQAKLVSQFGADHEIFTHNNRIAIQGLRPEALPADVQAASESILTAVP
CEEEEECCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
AAVQSSRLFHPEDTIIKTPHSVIGGNQFVMMAGPCSVESAEHVDQMAAVAKQGGATIVRG
HHHHHCCCCCCCCCEEECCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEC
GAFKPRTSPYSFQGLGETGLQYLRTAADKHGLDMITEVMDDEHVAMVAKYTDIFQIGARN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
MQNFSLLKAVGQTQIPVALKRGMSATIDDVLNAAEYIAAGGNHQIMLLERGIRTFDNKYT
CHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHCCCCC
RNTFDLGAVPVLQSLTHYPVIVDPSHAVGTWELVTPMAMAGVAAGASGMIVEIHDQPTQA
CCCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHH
LSDGPQALKPATYLKMAQQAFQLHDLMQTWA
HCCCCHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]