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The map label for this gene is pts11BC [H]

Identifier: 28377719

GI number: 28377719

Start: 816429

End: 817880

Strand: Direct

Name: pts11BC [H]

Synonym: lp_0886

Alternate gene names: 28377719

Gene position: 816429-817880 (Clockwise)

Preceding gene: 28377718

Following gene: 28377720

Centisome position: 24.68

GC content: 39.53

Gene sequence:

>1452_bases
ATGAAAAATAAGGATAAACAGTATGAAAAAGTGGCGAATGGTGTACTGGAAGCAGTTGGTGGTAGTGCGAATATTTCTTC
GGTGACACATTGTATGACCCGATTACGTTTTAATTTGAAGGATGAAAGTATTCCTAATGATGGTGAGGTACAGAATATTC
CAGGTGTGATTGGTGTCAATCGCGCTGGTGGCCAGTATCAAATCATTATTGGACAAGCAGTTAGCAAAGTTTATGATGCG
TTACTTACGGTGGGGAATTTAACTAGAAACGCGCCAATTAATGAAGATTTAGATAATCGACCTAAAGAAAAGTTAACGTT
TAAGTCTGCGGGAAATATGATTCTAAATAAATTGGCTGGATGTTTAACACCATTGATTCCGATGTTGATTGCTGCATCAA
TGTTTAAAATGTTTGCGGCCATTTTAGGACCAAGCATGTTCAATGTTCTTGGTACTAAAACATCGTTGTATCAGTTATTT
ACGTTGGTTGGTGATGCTGGATTCTACTTTTTTCCAATCATCTTAGGATATACAGCTGCTAAGCAATTTAATACGTCACG
GATTATTTCAATGTTTTTAGGTGCAATTTTGATTGATCCTAATTTAATTAAAATTGTGACTGCTGGCAAGGCATTTAATA
TCTTCGGTATCGCAATGCCATTAGTTAATTATTCAAGTACGGTCATTCCAATTATTTTGTCGGTTTGGGTAATGTCGTAT
ATTGAACGGTTCTTTAAGCGTTATGTACCAGAGTCGATTAGTACGATTGTTATCCCAACGTTGACGATTGCAATCATGTT
GCCGATTTCGTTATGTATTTTAGGCCCAGCAGGAAACTTTATCGGCAATTACATTTGTACAGGAATATTGGCTTTTGGAA
AATTAGGTGGCTTGCCAACGATTATCGCGGTTGGAGTGGTTGGTGCCTTATGGGAAATCTTGGTTATGACCGGGATGCAT
CTCTTAATGCTTACGACGATGATGATGATTTTTGCGCAATCGGGTCATGAAAACTTTGTCACACTTGGCGCAGTTGCCGC
TAGTATGTCGGTCGCGGGCATGTGTTTGGGTGCGGCCTTACGAATTAAGGACCAAGATCAAAAGACACTTGCTTGGGGTT
ATTTAATCGCTAGTATTATCGGAGGTGTGACTGAACCAGGATTATATGGACTAGCAATTCGTTATAAACGACCGTTTATT
GGCATGATGATTGGTGGATTTTGCGGTGGCTTATATGCTGGCCTGACAACAGTTACAGCTTATGTCATGGTACCTGTTGC
AAACTTTTTATCTTTAACTGCGTATGTTGGCGGGCAAACATCTAATGTGATTAACGGTGTGGTTAGTGGCGTGATTGCGT
TTGTAGCAGCTGCTATTGCAACTTATGCGATTGGTGTTGAAGCCAATACAAACAAACAGGGGACTAAAGAATTTAAACTA
GTGGAGGCTTAA

Upstream 100 bases:

>100_bases
TAATGATGATGAACTTTTCTATCTAATGATATATGTTAAAAGAATCGTTAATAAAATAAATACTCAAGCGTAACCGTTAA
TTAATGGAGGTGTATGCGAC

Downstream 100 bases:

>100_bases
AAGCTAATGGAAAGAAAAGTAATCGTTCGAGCTGATGATTTAGGTTATTCCGATGCAGTTAATGTTGGGATTGCACGAAC
AGTTCACAACGGGTTAATTA

Product: beta-glucosides PTS, EIIBC

Products: NA

Alternate protein names: EIIBCA-Bgl; EII-Bgl; Beta-glucoside-specific phosphotransferase enzyme IIB component; PTS system beta-glucoside-specific EIIB component; Beta-glucoside permease IIC component; PTS system beta-glucoside-specific EIIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component; PTS system beta-glucoside-specific EIIA component [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MKNKDKQYEKVANGVLEAVGGSANISSVTHCMTRLRFNLKDESIPNDGEVQNIPGVIGVNRAGGQYQIIIGQAVSKVYDA
LLTVGNLTRNAPINEDLDNRPKEKLTFKSAGNMILNKLAGCLTPLIPMLIAASMFKMFAAILGPSMFNVLGTKTSLYQLF
TLVGDAGFYFFPIILGYTAAKQFNTSRIISMFLGAILIDPNLIKIVTAGKAFNIFGIAMPLVNYSSTVIPIILSVWVMSY
IERFFKRYVPESISTIVIPTLTIAIMLPISLCILGPAGNFIGNYICTGILAFGKLGGLPTIIAVGVVGALWEILVMTGMH
LLMLTTMMMIFAQSGHENFVTLGAVAASMSVAGMCLGAALRIKDQDQKTLAWGYLIASIIGGVTEPGLYGLAIRYKRPFI
GMMIGGFCGGLYAGLTTVTAYVMVPVANFLSLTAYVGGQTSNVINGVVSGVIAFVAAAIATYAIGVEANTNKQGTKEFKL
VEA

Sequences:

>Translated_483_residues
MKNKDKQYEKVANGVLEAVGGSANISSVTHCMTRLRFNLKDESIPNDGEVQNIPGVIGVNRAGGQYQIIIGQAVSKVYDA
LLTVGNLTRNAPINEDLDNRPKEKLTFKSAGNMILNKLAGCLTPLIPMLIAASMFKMFAAILGPSMFNVLGTKTSLYQLF
TLVGDAGFYFFPIILGYTAAKQFNTSRIISMFLGAILIDPNLIKIVTAGKAFNIFGIAMPLVNYSSTVIPIILSVWVMSY
IERFFKRYVPESISTIVIPTLTIAIMLPISLCILGPAGNFIGNYICTGILAFGKLGGLPTIIAVGVVGALWEILVMTGMH
LLMLTTMMMIFAQSGHENFVTLGAVAASMSVAGMCLGAALRIKDQDQKTLAWGYLIASIIGGVTEPGLYGLAIRYKRPFI
GMMIGGFCGGLYAGLTTVTAYVMVPVANFLSLTAYVGGQTSNVINGVVSGVIAFVAAAIATYAIGVEANTNKQGTKEFKL
VEA
>Mature_483_residues
MKNKDKQYEKVANGVLEAVGGSANISSVTHCMTRLRFNLKDESIPNDGEVQNIPGVIGVNRAGGQYQIIIGQAVSKVYDA
LLTVGNLTRNAPINEDLDNRPKEKLTFKSAGNMILNKLAGCLTPLIPMLIAASMFKMFAAILGPSMFNVLGTKTSLYQLF
TLVGDAGFYFFPIILGYTAAKQFNTSRIISMFLGAILIDPNLIKIVTAGKAFNIFGIAMPLVNYSSTVIPIILSVWVMSY
IERFFKRYVPESISTIVIPTLTIAIMLPISLCILGPAGNFIGNYICTGILAFGKLGGLPTIIAVGVVGALWEILVMTGMH
LLMLTTMMMIFAQSGHENFVTLGAVAASMSVAGMCLGAALRIKDQDQKTLAWGYLIASIIGGVTEPGLYGLAIRYKRPFI
GMMIGGFCGGLYAGLTTVTAYVMVPVANFLSLTAYVGGQTSNVINGVVSGVIAFVAAAIATYAIGVEANTNKQGTKEFKL
VEA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994906, Length=468, Percent_Identity=33.1196581196581, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790159, Length=467, Percent_Identity=32.1199143468951, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI2367362, Length=425, Percent_Identity=26.5882352941176, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788769, Length=423, Percent_Identity=25.7683215130024, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011297 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 51506; Mature: 51506

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKDKQYEKVANGVLEAVGGSANISSVTHCMTRLRFNLKDESIPNDGEVQNIPGVIGVN
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEC
RAGGQYQIIIGQAVSKVYDALLTVGNLTRNAPINEDLDNRPKEKLTFKSAGNMILNKLAG
CCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHH
CLTPLIPMLIAASMFKMFAAILGPSMFNVLGTKTSLYQLFTLVGDAGFYFFPIILGYTAA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KQFNTSRIISMFLGAILIDPNLIKIVTAGKAFNIFGIAMPLVNYSSTVIPIILSVWVMSY
HHCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IERFFKRYVPESISTIVIPTLTIAIMLPISLCILGPAGNFIGNYICTGILAFGKLGGLPT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
IIAVGVVGALWEILVMTGMHLLMLTTMMMIFAQSGHENFVTLGAVAASMSVAGMCLGAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHE
RIKDQDQKTLAWGYLIASIIGGVTEPGLYGLAIRYKRPFIGMMIGGFCGGLYAGLTTVTA
EECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
YVMVPVANFLSLTAYVGGQTSNVINGVVSGVIAFVAAAIATYAIGVEANTNKQGTKEFKL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
VEA
ECC
>Mature Secondary Structure
MKNKDKQYEKVANGVLEAVGGSANISSVTHCMTRLRFNLKDESIPNDGEVQNIPGVIGVN
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEC
RAGGQYQIIIGQAVSKVYDALLTVGNLTRNAPINEDLDNRPKEKLTFKSAGNMILNKLAG
CCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHH
CLTPLIPMLIAASMFKMFAAILGPSMFNVLGTKTSLYQLFTLVGDAGFYFFPIILGYTAA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KQFNTSRIISMFLGAILIDPNLIKIVTAGKAFNIFGIAMPLVNYSSTVIPIILSVWVMSY
HHCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IERFFKRYVPESISTIVIPTLTIAIMLPISLCILGPAGNFIGNYICTGILAFGKLGGLPT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
IIAVGVVGALWEILVMTGMHLLMLTTMMMIFAQSGHENFVTLGAVAASMSVAGMCLGAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHE
RIKDQDQKTLAWGYLIASIIGGVTEPGLYGLAIRYKRPFIGMMIGGFCGGLYAGLTTVTA
EECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
YVMVPVANFLSLTAYVGGQTSNVINGVVSGVIAFVAAAIATYAIGVEANTNKQGTKEFKL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
VEA
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377; 8628237 [H]