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The map label for this gene is zur [H]

Identifier: 28377707

GI number: 28377707

Start: 806124

End: 806567

Strand: Direct

Name: zur [H]

Synonym: lp_0868

Alternate gene names: 28377707

Gene position: 806124-806567 (Clockwise)

Preceding gene: 28377706

Following gene: 28377708

Centisome position: 24.37

GC content: 42.12

Gene sequence:

>444_bases
ATGGAAACACCAATTGAACAAGCCGTCGCAATTTTACGTCGCAATCAGTTTAAAATTACGAAGCAACGGCAGGCATTATT
AGATTATCTGGTGACCTATCAGGACCACTATGTGGCAATTTCGGCCGTTGATGAGCACATGCGGACCTTATTTGCAGGAA
TGAGTCACAATACCATTTATCGCAATATTAAAGAGTTTGAAACGTTAGGATTATTGGAATTGAAGGCCCAGGCTAATCAA
ACCCTGGTTAAATATCAATGTGATTTCAAGCATCAACACCATCACCATTTTGTTTGTTCAAACTGTGGTAAGGTGACGGA
ACTGCAAGCGTGTCCGTTAGACGAGTATGAAGCACAATTACCGGGTTGTACGATTACGGGTCACCGCATCGAGATTTACG
GTCTATGTGCCAATTGCACGAAAAAGCAGGCAATTAATAGCTGA

Upstream 100 bases:

>100_bases
TAGACGGTCAACGTAATTCACTTTTACACTTGAGTATGCTAAACTAAATAGTAATGATTATGATTTAGTGAAGTCCTGGT
CAGTAGGAGGCAGCAACATT

Downstream 100 bases:

>100_bases
CGGGGAGTCGGCTTTTTTGTTGGCCTTGTTTGAGTAAAGAGTTTCTTAATTTGTGATAGAATTAGTGCATTCCGAACACG
AGCATGGTTTAATTATAGAT

Product: metal uptake regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
METPIEQAVAILRRNQFKITKQRQALLDYLVTYQDHYVAISAVDEHMRTLFAGMSHNTIYRNIKEFETLGLLELKAQANQ
TLVKYQCDFKHQHHHHFVCSNCGKVTELQACPLDEYEAQLPGCTITGHRIEIYGLCANCTKKQAINS

Sequences:

>Translated_147_residues
METPIEQAVAILRRNQFKITKQRQALLDYLVTYQDHYVAISAVDEHMRTLFAGMSHNTIYRNIKEFETLGLLELKAQANQ
TLVKYQCDFKHQHHHHFVCSNCGKVTELQACPLDEYEAQLPGCTITGHRIEIYGLCANCTKKQAINS
>Mature_147_residues
METPIEQAVAILRRNQFKITKQRQALLDYLVTYQDHYVAISAVDEHMRTLFAGMSHNTIYRNIKEFETLGLLELKAQANQ
TLVKYQCDFKHQHHHHFVCSNCGKVTELQACPLDEYEAQLPGCTITGHRIEIYGLCANCTKKQAINS

Specific function: Required for the zinc-specific repression of two operons implicated in zinc uptake, yciC and ycdHIyceA. Also represses the expression of rpmE2, the gene for ribosomal protein L31B, which is expressed only after the end of exponential growth [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16897; Mature: 16897

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METPIEQAVAILRRNQFKITKQRQALLDYLVTYQDHYVAISAVDEHMRTLFAGMSHNTIY
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCHHH
RNIKEFETLGLLELKAQANQTLVKYQCDFKHQHHHHFVCSNCGKVTELQACPLDEYEAQL
HHHHHHHHHCHHEECCCCCCEEEEEEECCCCCCCCEEEECCCCCCCEECCCCCCHHHHCC
PGCTITGHRIEIYGLCANCTKKQAINS
CCEEEECCEEEEEEEECCCCCHHCCCC
>Mature Secondary Structure
METPIEQAVAILRRNQFKITKQRQALLDYLVTYQDHYVAISAVDEHMRTLFAGMSHNTIY
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCHHH
RNIKEFETLGLLELKAQANQTLVKYQCDFKHQHHHHFVCSNCGKVTELQACPLDEYEAQL
HHHHHHHHHCHHEECCCCCCEEEEEEECCCCCCCCEEEECCCCCCCEECCCCCCHHHHCC
PGCTITGHRIEIYGLCANCTKKQAINS
CCEEEECCEEEEEEEECCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9811636 [H]