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The map label for this gene is kup1

Identifier: 28377411

GI number: 28377411

Start: 470486

End: 472468

Strand: Direct

Name: kup1

Synonym: lp_0525

Alternate gene names: 28377411

Gene position: 470486-472468 (Clockwise)

Preceding gene: 28377410

Following gene: 28377414

Centisome position: 14.22

GC content: 48.92

Gene sequence:

>1983_bases
ATGAGTAAACAGGCTCAGTTCAATAAGCATCGGGTGGCAGGATTGTTAGTCGCGATGGGTGTTGTATATGGTGATATTGG
AACCAGTCCGTTATACGTGATGAAGGCCATCATTACCGGTCAAGGTGGGATGCAGGCCGTTGATGAGAAGTTTATGTTGG
GGGCCGTCTCGCTAGTTTTTTGGACAATGACGCTGCTCACGACCGTTAAGTACGTTTTGATCGCGTTAAACGCGGATAAT
CATGGCGAAGGCGGTATCTTTTCACTATTCGCATTGGTGCGTCATCGTGCGCGCTGGTTAGTCATTCCTGCCATGATTGG
TGGGGCTGCGTTACTGGCGGATGGGGCGCTAACCCCCGCAGTGACAGTTACGACTGCCATCGAAGGCTTACGCGATGTAC
CAGCATACGTTCAACTGTTTGGTGCCAGCCAAAATACGATTATACTGATTACGCTTGGAATTATCACCCTATTATTTATG
CTGCAACGTTTTGGAACGAACACGATTGGCAAGTTATTTGGCCCCATCATGTTGGGCTGGTTCACGTTTTTGGGAGTCAG
TGGCTTCGTTAATCTGGTGCAGGATTGGACGATCCTGCGTGCACTGAATCCCTATTATGCGTGGTTACTCTTGATCAGCC
CGGCGAACAAAGTGGGAATCTTGATTCTAGGGAGCGTCTTTCTGGCAACGACCGGTGCTGAGGCCCTATACAGTGACCTT
GGGCACGTCGGCAAAACGAATATTCGGTTGAGCTGGCCGTATGTCAAAGTTTGTCTACTACTCAGCTATTTCGGTCAGGC
CGCATGGATTTTAGGTCCCGGCCAAGCGATTCAGGGACATGTGAATCCCTTTTTTGCAATGTTACCTGCTAGCCTGACGA
TGGCGGCAGTGATTTTTGCGACGCTCGCGGCCATTATCGCGTCACAGTCGCTGATCAGTGGGTCGTTTACGTTAGTTAGT
GAAGCGATTCGACTGAAACTATTCCCCCGATTACTGACTACTTACCCCGGTAAAGCAGTGGGCCAAATGTATTTACCGGT
CGTTAACTGGGGGCTGTGGGGCGTGACGAGTATGCTGGTGATTTTCTTTCAAACTAGTGAAAGAATGGAAGCTGCATACG
GGTTAGCCATCACACTGACAATGCTGATGACGACCACTTTGATCTACGCGTTTTTACGGCAAAAGCGCTTACCATTAATC
GGTGCGGGACTACTGACCGGTTTCTTCGCGACCATCGAAGTGATTTTCCTGATTGCCAGCGCAGCCAAGTTCTGGCACGG
CGGCTACGTAGCGGTCGGACTTGCTTTACTAATTTTCCTAGTGATGGCCGTGTGGTATCGTGGCGAACAAATTGTCCGAC
AACATAACCACCCGCTTAGTTTACGACAATATCAGGACCAGCTTGCTAAGTTACGCGACGATCAGACGGTGGACAAGTTC
CAGACGAACGTCGTCTTCCTAACAAGCCGAATGGATGGCGACCAAGTGGAGCGAAAGGTATTATATTCGATTTTAGACAA
GTGGCCGAAACGTGCCGACGTCTACTGGTTTGTTAATGTGACAATCACGGATGAACCGTATACCGCGGAGTATACTGTCG
ACACGTTAGCAACGGACTATTTGGTAACTGTTAAGTTATACCTGGGCTTTCGTGTCCGCCAAGATATTAACCGCTATTTA
CGGACGATTGTCCGCGACTTAATGGCTACTGGACGTTTAGCGGCGCAAAAGCAGACATATTCAGTCACTTCTGGCCGCGA
TGTCGGTGACTTCCGCTTCGTTATCATCGAGGAGAAGTTAGAAAATGGTAGTCGGTTATCCCGCTTGGATCGATTAGTGA
TCGAGACGAAATTAATGATTAAAAAATACGCGACAACGCCTGCCAAATGGTTCGGCCTAGAATTCTCCGAGGTGACTCTT
GAAACCGTTCCAATTCTATTCAATGAGATCCCGGCGTTACCGATCACTGAAAGACAACGTTAA

Upstream 100 bases:

>100_bases
GATTGTCTTTCTGACGACGATTAGGTAAGCTAGTTGAACCCATTATAACGAGGGACGATTGGCTGTAAATCGTGAATATC
GCTGAAAGGATGGGGGCATA

Downstream 100 bases:

>100_bases
CGACATTATCAGTATTTGGAGATTTCGCTCAAATGAAATGGCTAAGGCCAAAATAAAGCACCTATCGAAAATTGATAGGT
GCTTTATTTTAGTGCTGCCA

Product: potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MSKQAQFNKHRVAGLLVAMGVVYGDIGTSPLYVMKAIITGQGGMQAVDEKFMLGAVSLVFWTMTLLTTVKYVLIALNADN
HGEGGIFSLFALVRHRARWLVIPAMIGGAALLADGALTPAVTVTTAIEGLRDVPAYVQLFGASQNTIILITLGIITLLFM
LQRFGTNTIGKLFGPIMLGWFTFLGVSGFVNLVQDWTILRALNPYYAWLLLISPANKVGILILGSVFLATTGAEALYSDL
GHVGKTNIRLSWPYVKVCLLLSYFGQAAWILGPGQAIQGHVNPFFAMLPASLTMAAVIFATLAAIIASQSLISGSFTLVS
EAIRLKLFPRLLTTYPGKAVGQMYLPVVNWGLWGVTSMLVIFFQTSERMEAAYGLAITLTMLMTTTLIYAFLRQKRLPLI
GAGLLTGFFATIEVIFLIASAAKFWHGGYVAVGLALLIFLVMAVWYRGEQIVRQHNHPLSLRQYQDQLAKLRDDQTVDKF
QTNVVFLTSRMDGDQVERKVLYSILDKWPKRADVYWFVNVTITDEPYTAEYTVDTLATDYLVTVKLYLGFRVRQDINRYL
RTIVRDLMATGRLAAQKQTYSVTSGRDVGDFRFVIIEEKLENGSRLSRLDRLVIETKLMIKKYATTPAKWFGLEFSEVTL
ETVPILFNEIPALPITERQR

Sequences:

>Translated_660_residues
MSKQAQFNKHRVAGLLVAMGVVYGDIGTSPLYVMKAIITGQGGMQAVDEKFMLGAVSLVFWTMTLLTTVKYVLIALNADN
HGEGGIFSLFALVRHRARWLVIPAMIGGAALLADGALTPAVTVTTAIEGLRDVPAYVQLFGASQNTIILITLGIITLLFM
LQRFGTNTIGKLFGPIMLGWFTFLGVSGFVNLVQDWTILRALNPYYAWLLLISPANKVGILILGSVFLATTGAEALYSDL
GHVGKTNIRLSWPYVKVCLLLSYFGQAAWILGPGQAIQGHVNPFFAMLPASLTMAAVIFATLAAIIASQSLISGSFTLVS
EAIRLKLFPRLLTTYPGKAVGQMYLPVVNWGLWGVTSMLVIFFQTSERMEAAYGLAITLTMLMTTTLIYAFLRQKRLPLI
GAGLLTGFFATIEVIFLIASAAKFWHGGYVAVGLALLIFLVMAVWYRGEQIVRQHNHPLSLRQYQDQLAKLRDDQTVDKF
QTNVVFLTSRMDGDQVERKVLYSILDKWPKRADVYWFVNVTITDEPYTAEYTVDTLATDYLVTVKLYLGFRVRQDINRYL
RTIVRDLMATGRLAAQKQTYSVTSGRDVGDFRFVIIEEKLENGSRLSRLDRLVIETKLMIKKYATTPAKWFGLEFSEVTL
ETVPILFNEIPALPITERQR
>Mature_659_residues
SKQAQFNKHRVAGLLVAMGVVYGDIGTSPLYVMKAIITGQGGMQAVDEKFMLGAVSLVFWTMTLLTTVKYVLIALNADNH
GEGGIFSLFALVRHRARWLVIPAMIGGAALLADGALTPAVTVTTAIEGLRDVPAYVQLFGASQNTIILITLGIITLLFML
QRFGTNTIGKLFGPIMLGWFTFLGVSGFVNLVQDWTILRALNPYYAWLLLISPANKVGILILGSVFLATTGAEALYSDLG
HVGKTNIRLSWPYVKVCLLLSYFGQAAWILGPGQAIQGHVNPFFAMLPASLTMAAVIFATLAAIIASQSLISGSFTLVSE
AIRLKLFPRLLTTYPGKAVGQMYLPVVNWGLWGVTSMLVIFFQTSERMEAAYGLAITLTMLMTTTLIYAFLRQKRLPLIG
AGLLTGFFATIEVIFLIASAAKFWHGGYVAVGLALLIFLVMAVWYRGEQIVRQHNHPLSLRQYQDQLAKLRDDQTVDKFQ
TNVVFLTSRMDGDQVERKVLYSILDKWPKRADVYWFVNVTITDEPYTAEYTVDTLATDYLVTVKLYLGFRVRQDINRYLR
TIVRDLMATGRLAAQKQTYSVTSGRDVGDFRFVIIEEKLENGSRLSRLDRLVIETKLMIKKYATTPAKWFGLEFSEVTLE
TVPILFNEIPALPITERQR

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=474, Percent_Identity=37.5527426160338, Blast_Score=274, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP1_LACPL (Q88Z42)

Other databases:

- EMBL:   AL935253
- RefSeq:   NP_784303.1
- GeneID:   1061850
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0525
- NMPDR:   fig|220668.1.peg.437
- HOGENOM:   HBG351154
- OMA:   IASAWSK
- ProtClustDB:   CLSK433337
- BioCyc:   LPLA220668:LP_0525-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 73364; Mature: 73232

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xce6f364)-; HASH(0xca33ea0)-; HASH(0xc4e43ec)-; HASH(0xcaaa144)-; HASH(0xcac6c48)-; HASH(0xcd1e7b8)-; HASH(0xc208568)-; HASH(0xbf054a8)-; HASH(0xcd1e8d8)-; HASH(0xcac939c)-; HASH(0xc3407ac)-; HASH(0xca6ac60)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQAQFNKHRVAGLLVAMGVVYGDIGTSPLYVMKAIITGQGGMQAVDEKFMLGAVSLVF
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
WTMTLLTTVKYVLIALNADNHGEGGIFSLFALVRHRARWLVIPAMIGGAALLADGALTPA
HHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCCEEEEHHHHCCHHHHCCCCCCCH
VTVTTAIEGLRDVPAYVQLFGASQNTIILITLGIITLLFMLQRFGTNTIGKLFGPIMLGW
HHHHHHHHHHHCCHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FTFLGVSGFVNLVQDWTILRALNPYYAWLLLISPANKVGILILGSVFLATTGAEALYSDL
HHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCHHEEHHHHHHHCCHHHHHHHH
GHVGKTNIRLSWPYVKVCLLLSYFGQAAWILGPGQAIQGHVNPFFAMLPASLTMAAVIFA
CCCCCCCEEEECHHHHHHHHHHHHCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHH
TLAAIIASQSLISGSFTLVSEAIRLKLFPRLLTTYPGKAVGQMYLPVVNWGLWGVTSMLV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHH
IFFQTSERMEAAYGLAITLTMLMTTTLIYAFLRQKRLPLIGAGLLTGFFATIEVIFLIAS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
AAKFWHGGYVAVGLALLIFLVMAVWYRGEQIVRQHNHPLSLRQYQDQLAKLRDDQTVDKF
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHH
QTNVVFLTSRMDGDQVERKVLYSILDKWPKRADVYWFVNVTITDEPYTAEYTVDTLATDY
HCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEEEHHHHHHHH
LVTVKLYLGFRVRQDINRYLRTIVRDLMATGRLAAQKQTYSVTSGRDVGDFRFVIIEEKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEECCCCCCCCEEEEEEEHHH
ENGSRLSRLDRLVIETKLMIKKYATTPAKWFGLEFSEVTLETVPILFNEIPALPITERQR
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
SKQAQFNKHRVAGLLVAMGVVYGDIGTSPLYVMKAIITGQGGMQAVDEKFMLGAVSLVF
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
WTMTLLTTVKYVLIALNADNHGEGGIFSLFALVRHRARWLVIPAMIGGAALLADGALTPA
HHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCCEEEEHHHHCCHHHHCCCCCCCH
VTVTTAIEGLRDVPAYVQLFGASQNTIILITLGIITLLFMLQRFGTNTIGKLFGPIMLGW
HHHHHHHHHHHCCHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FTFLGVSGFVNLVQDWTILRALNPYYAWLLLISPANKVGILILGSVFLATTGAEALYSDL
HHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCHHEEHHHHHHHCCHHHHHHHH
GHVGKTNIRLSWPYVKVCLLLSYFGQAAWILGPGQAIQGHVNPFFAMLPASLTMAAVIFA
CCCCCCCEEEECHHHHHHHHHHHHCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHH
TLAAIIASQSLISGSFTLVSEAIRLKLFPRLLTTYPGKAVGQMYLPVVNWGLWGVTSMLV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHH
IFFQTSERMEAAYGLAITLTMLMTTTLIYAFLRQKRLPLIGAGLLTGFFATIEVIFLIAS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
AAKFWHGGYVAVGLALLIFLVMAVWYRGEQIVRQHNHPLSLRQYQDQLAKLRDDQTVDKF
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHH
QTNVVFLTSRMDGDQVERKVLYSILDKWPKRADVYWFVNVTITDEPYTAEYTVDTLATDY
HCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEEEHHHHHHHH
LVTVKLYLGFRVRQDINRYLRTIVRDLMATGRLAAQKQTYSVTSGRDVGDFRFVIIEEKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEECCCCCCCCEEEEEEEHHH
ENGSRLSRLDRLVIETKLMIKKYATTPAKWFGLEFSEVTLETVPILFNEIPALPITERQR
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12566566