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The map label for this gene is acpS

Identifier: 28377408

GI number: 28377408

Start: 467904

End: 468266

Strand: Direct

Name: acpS

Synonym: lp_0522

Alternate gene names: 28377408

Gene position: 467904-468266 (Clockwise)

Preceding gene: 28377407

Following gene: 28377409

Centisome position: 14.14

GC content: 45.45

Gene sequence:

>363_bases
GTGATTTATGGTACCGGCATTGATTTAACTGAGCTTAGTCGGATTGAAGCGATTCTAGCGAAGGGACTGAGATTGCCTGA
AAAGATCTTAACACCGGCTGAGTTGGCGGTGTTTTCACGTTACCCGGTTAAACGCCAGATCGAGTTTATGGCAGGGCGTT
TTTCAGCTAAGGAAGCATATAGTAAGGCATATGGCACGGGAATTGGTGCGGCAGTTGGATTTCAAGATATCGAAATTTTA
GACAACGCCCAGGGTAAACCGGAAGTTACGCGCCACCCGTTTGATGGTCCAGCGTGGATTTCAATTTCACACACGGATAC
GTTAGTAATGACACAAGTTATATTGGAAAGAGGCAATTTGTGA

Upstream 100 bases:

>100_bases
GATTGCGTGTATGGGCCCTTTTATCGCGGCGGTAGCTGTGGTAAATTGGAAACATCAGCCTAAGTTGACGTGATAATAAT
GAGATAGAGGGGGTCACAGC

Downstream 100 bases:

>100_bases
TGGTTGTAATTGGGGAGCACCGCCACACACAAGTCACAGTCGACTTGCAGGCAATTAAGACAAATATTAGTAATGAAATG
GCGCAAAAGGATGAGTTGAC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MIYGTGIDLTELSRIEAILAKGLRLPEKILTPAELAVFSRYPVKRQIEFMAGRFSAKEAYSKAYGTGIGAAVGFQDIEIL
DNAQGKPEVTRHPFDGPAWISISHTDTLVMTQVILERGNL

Sequences:

>Translated_120_residues
MIYGTGIDLTELSRIEAILAKGLRLPEKILTPAELAVFSRYPVKRQIEFMAGRFSAKEAYSKAYGTGIGAAVGFQDIEIL
DNAQGKPEVTRHPFDGPAWISISHTDTLVMTQVILERGNL
>Mature_120_residues
MIYGTGIDLTELSRIEAILAKGLRLPEKILTPAELAVFSRYPVKRQIEFMAGRFSAKEAYSKAYGTGIGAAVGFQDIEIL
DNAQGKPEVTRHPFDGPAWISISHTDTLVMTQVILERGNL

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=89, Percent_Identity=38.2022471910112, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_LACPL (Q88Z44)

Other databases:

- EMBL:   AL935253
- RefSeq:   NP_784300.1
- ProteinModelPortal:   Q88Z44
- SMR:   Q88Z44
- GeneID:   1061816
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0522
- NMPDR:   fig|220668.1.peg.434
- HOGENOM:   HBG734479
- OMA:   VHVSITH
- ProtClustDB:   PRK00070
- BioCyc:   LPLA220668:LP_0522-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13193; Mature: 13193

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGTGIDLTELSRIEAILAKGLRLPEKILTPAELAVFSRYPVKRQIEFMAGRFSAKEAY
CEECCCCCHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
SKAYGTGIGAAVGFQDIEILDNAQGKPEVTRHPFDGPAWISISHTDTLVMTQVILERGNL
HHHHCCCCCHHCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MIYGTGIDLTELSRIEAILAKGLRLPEKILTPAELAVFSRYPVKRQIEFMAGRFSAKEAY
CEECCCCCHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
SKAYGTGIGAAVGFQDIEILDNAQGKPEVTRHPFDGPAWISISHTDTLVMTQVILERGNL
HHHHCCCCCHHCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566