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The map label for this gene is fucP [H]

Identifier: 28377389

GI number: 28377389

Start: 444805

End: 446169

Strand: Direct

Name: fucP [H]

Synonym: lp_0498

Alternate gene names: 28377389

Gene position: 444805-446169 (Clockwise)

Preceding gene: 28377388

Following gene: 28377390

Centisome position: 13.45

GC content: 43.96

Gene sequence:

>1365_bases
ATGCAAAAGTTATTTCGGGGTGTGATTAAGCTATCAGCCCATGAGCAAGATGATGGTTATTTGGATAAAACACCGATTTT
CCAGTTCATGCTATTGTCATTACTCATTCCTTTGTGGGCTGCGGCAGCCAGCTTAAATAACATCTTAATTACGCAATTTA
AGACTATTTTTGAATTGAATAATGCAACGAGTGCCTTAGTCAACAGTGCATTTTATCTGGGCTATTTCGTCATTGCGATT
CCAGCTAGTCGGGTTATCAAAAAGACGTCGTATAAGTTAGCAATCGTAATCGGACTGAGCTTATTTACGATTGGCTGCTT
GCTCTTTTTCCCAGCGTCTCACTTAGCCACATACGGGGTGTTCTTAATTGCATTATTTGCCATTGCATGTGGACTTAGCT
TTCTGGAGACGAGTGCGAATACGTTCAGTACGTTGATGGGACCTAAGTCGGCCTCAACCGTTCGACTAAATATTTCACAA
ATCTTTTATCCGATTGGTGCAGTCGTTGGAATCCTCCTGGGTAAGTATTTGATTTTCAACGATGGTGCCAGCCTGGCAAC
GACCATGGCAAAAATGCATGGTGCTGCTCGGTTAGCCTATGGACAGCGGATGTTACAGCAGACGCTGCTCCCGTATAAAT
ATCTGATTGTGGTATTACTTGTTGCAATTTTTATCTTTGTTTTGACACAGTTTCCAAGTGGCAAGCCTAAACAACGTTCA
GATCAAGCAGCCGCAAAATCAGCTGGTGTCGGTGAAACGCTACGTTATTTGATTCATAATAAGGACTTTATGAAGGGGAT
TGGTACGGAGTTTGTGTATATGGGCATGCAGACGGCGGTCTGGGCATACACAATCAACTTAGCGATGAGTTTTAGTAATC
GTATCAACGAGCGCGATGCCTCAACCTTTATGATTTATACCTATATTGCATTCTTCTGCGGCAAGCTATTGGCGACCGCG
TTAATGAAACGGTTTGCAACGGCGCAAGTTCTGTTTGGATTTTCAGTAGTGGGAACCCTCGCATTAGGCTATGTTACCTT
TGTCCCTAATGAGTCAGCGGTCTATCTGACGATTTTGGCGAGTGGCTTGTTCGGTCCGGGGTGGCCAACAATTTATTCAC
AAACGCTGGATACGGTTACTGATAAACGCTACACGGAAACTGCGGGAGCAATCGTTGTCATGTCGATTATTGGCGGTGCT
GTGACGCCGTTGATTCAAGGCTTGATTGCGGACATGACGGGGTCTGTTTCGTTGTCATTCATTATCGATGTTATTAGTTT
TGCAATTGTAGGTAGTTATGCACTTAGTTACTACAAGCGTCATCAGGCAGCGAGCGAAGTCACACATATGGAGGAGCTAT
TATGA

Upstream 100 bases:

>100_bases
TATCAGCAAGTATGGCAATTATTGGTAAGTAGTGATGGCTGAATGATTGCGCACCATTCCAGTTTAAAAAAAGAAAGCGC
TAACATCAAGGAGGGGAACC

Downstream 100 bases:

>100_bases
AAACAATTAAGTTATCGCATCAAATGTTTAGTCAATCAGAGTTTGAACTCTACAAAGATGATAATTTCAGTGCAAAAACA
TTTCTATATCCATCTGGAGT

Product: fucose transport protein

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: 6-deoxy-L-galactose permease; L-fucose permease [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MQKLFRGVIKLSAHEQDDGYLDKTPIFQFMLLSLLIPLWAAAASLNNILITQFKTIFELNNATSALVNSAFYLGYFVIAI
PASRVIKKTSYKLAIVIGLSLFTIGCLLFFPASHLATYGVFLIALFAIACGLSFLETSANTFSTLMGPKSASTVRLNISQ
IFYPIGAVVGILLGKYLIFNDGASLATTMAKMHGAARLAYGQRMLQQTLLPYKYLIVVLLVAIFIFVLTQFPSGKPKQRS
DQAAAKSAGVGETLRYLIHNKDFMKGIGTEFVYMGMQTAVWAYTINLAMSFSNRINERDASTFMIYTYIAFFCGKLLATA
LMKRFATAQVLFGFSVVGTLALGYVTFVPNESAVYLTILASGLFGPGWPTIYSQTLDTVTDKRYTETAGAIVVMSIIGGA
VTPLIQGLIADMTGSVSLSFIIDVISFAIVGSYALSYYKRHQAASEVTHMEELL

Sequences:

>Translated_454_residues
MQKLFRGVIKLSAHEQDDGYLDKTPIFQFMLLSLLIPLWAAAASLNNILITQFKTIFELNNATSALVNSAFYLGYFVIAI
PASRVIKKTSYKLAIVIGLSLFTIGCLLFFPASHLATYGVFLIALFAIACGLSFLETSANTFSTLMGPKSASTVRLNISQ
IFYPIGAVVGILLGKYLIFNDGASLATTMAKMHGAARLAYGQRMLQQTLLPYKYLIVVLLVAIFIFVLTQFPSGKPKQRS
DQAAAKSAGVGETLRYLIHNKDFMKGIGTEFVYMGMQTAVWAYTINLAMSFSNRINERDASTFMIYTYIAFFCGKLLATA
LMKRFATAQVLFGFSVVGTLALGYVTFVPNESAVYLTILASGLFGPGWPTIYSQTLDTVTDKRYTETAGAIVVMSIIGGA
VTPLIQGLIADMTGSVSLSFIIDVISFAIVGSYALSYYKRHQAASEVTHMEELL
>Mature_454_residues
MQKLFRGVIKLSAHEQDDGYLDKTPIFQFMLLSLLIPLWAAAASLNNILITQFKTIFELNNATSALVNSAFYLGYFVIAI
PASRVIKKTSYKLAIVIGLSLFTIGCLLFFPASHLATYGVFLIALFAIACGLSFLETSANTFSTLMGPKSASTVRLNISQ
IFYPIGAVVGILLGKYLIFNDGASLATTMAKMHGAARLAYGQRMLQQTLLPYKYLIVVLLVAIFIFVLTQFPSGKPKQRS
DQAAAKSAGVGETLRYLIHNKDFMKGIGTEFVYMGMQTAVWAYTINLAMSFSNRINERDASTFMIYTYIAFFCGKLLATA
LMKRFATAQVLFGFSVVGTLALGYVTFVPNESAVYLTILASGLFGPGWPTIYSQTLDTVTDKRYTETAGAIVVMSIIGGA
VTPLIQGLIADMTGSVSLSFIIDVISFAIVGSYALSYYKRHQAASEVTHMEELL

Specific function: Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=420, Percent_Identity=32.6190476190476, Blast_Score=227, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49557; Mature: 49557

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLFRGVIKLSAHEQDDGYLDKTPIFQFMLLSLLIPLWAAAASLNNILITQFKTIFELN
CHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NATSALVNSAFYLGYFVIAIPASRVIKKTSYKLAIVIGLSLFTIGCLLFFPASHLATYGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLIALFAIACGLSFLETSANTFSTLMGPKSASTVRLNISQIFYPIGAVVGILLGKYLIFN
HHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEC
DGASLATTMAKMHGAARLAYGQRMLQQTLLPYKYLIVVLLVAIFIFVLTQFPSGKPKQRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DQAAAKSAGVGETLRYLIHNKDFMKGIGTEFVYMGMQTAVWAYTINLAMSFSNRINERDA
HHHHHHHCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
STFMIYTYIAFFCGKLLATALMKRFATAQVLFGFSVVGTLALGYVTFVPNESAVYLTILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEHHHHH
SGLFGPGWPTIYSQTLDTVTDKRYTETAGAIVVMSIIGGAVTPLIQGLIADMTGSVSLSF
HCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
IIDVISFAIVGSYALSYYKRHQAASEVTHMEELL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQKLFRGVIKLSAHEQDDGYLDKTPIFQFMLLSLLIPLWAAAASLNNILITQFKTIFELN
CHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NATSALVNSAFYLGYFVIAIPASRVIKKTSYKLAIVIGLSLFTIGCLLFFPASHLATYGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLIALFAIACGLSFLETSANTFSTLMGPKSASTVRLNISQIFYPIGAVVGILLGKYLIFN
HHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEC
DGASLATTMAKMHGAARLAYGQRMLQQTLLPYKYLIVVLLVAIFIFVLTQFPSGKPKQRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DQAAAKSAGVGETLRYLIHNKDFMKGIGTEFVYMGMQTAVWAYTINLAMSFSNRINERDA
HHHHHHHCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
STFMIYTYIAFFCGKLLATALMKRFATAQVLFGFSVVGTLALGYVTFVPNESAVYLTILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEHHHHH
SGLFGPGWPTIYSQTLDTVTDKRYTETAGAIVVMSIIGGAVTPLIQGLIADMTGSVSLSF
HCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
IIDVISFAIVGSYALSYYKRHQAASEVTHMEELL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503; 2553671; 8052131; 2829831; 7783647 [H]